Screening for Osteoporosis
Abstract
At her annual visit, a 60-year-old woman asks her physician whether she should have a bone-density test to screen for osteoporosis. The patient went through menopause at the age of 52 years and received postmenopausal hormone therapy for four years. She takes 500 mg of calcium twice daily and exercises regularly. She has no personal history of fractures, but her mother had a hip fracture at the age of 82. Her height is 63 in. and her weight is 120 lb. What should her physician advise?
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
CT has a clear advantage over DXA BMD screening in its ability to accurately identify unsuspected osteoporotic compression fractures, which clearly diagnose osteoporosis independent of the patient's DXA T-score.
“One clear advantage of CT over DXA BMD screening is its ability to accurately identify unsuspected osteoporotic compression fractures, which clearly diagnose osteoporosis independent of the patient’s DXA T-score (1).”
From Opportunistic screening for osteoporosis using abdominal computed tomography scans obtained for other indications (2013) · cites this paper as [1]
This finding highlights the limitations of DXA, particularly in terms of BMD overestimation related to degenerative changes.
“this finding highlights the limitations of DXA, particularly in terms of BMD overestimation related to degenerative changes (1, 24).”
From Opportunistic screening for osteoporosis using abdominal computed tomography scans obtained for other indications (2013) · cites this paper as [1]
Osteoporosis remains substantially underdiagnosed and undertreated.
“Osteoporosis is prevalent and treatable and conveys a considerable lifetime fracture risk, yet it remains substantially underdiagnosed and undertreated (1-4).”
From Opportunistic screening for osteoporosis using abdominal computed tomography scans obtained for other indications (2013) · cites this paper as [1]
Cites
Osteoporosis Prevention, Diagnosis, and Therapy
NIH Consensus Development Panel on Osteoporosis Prevention, D. (2001) · JAMA: The Journal of the American Medical Association · doi:10.1001/jama.285.6.785 · Cited by 5,529 · see citing works
Risk Factors for Hip Fracture in White Women
Cummings, S. R., Nevitt, M. C., Browner, W. S., Stone, K., Fox, K. M., Ensrud, K. E., Cauley, J., Black, D., & Vogt, T. M. (1995) · New England Journal of Medicine · doi:10.1056/nejm199503233321202 · Cited by 3,595 · see citing works
Preventing Falls in Elderly Persons
Tinetti, M. E. (2003) · New England Journal of Medicine · doi:10.1056/nejmcp020719 · Cited by 1,660 · see citing works
Intentional and Unintentional Weight Loss Increase Bone Loss and Hip Fracture Risk in Older Women
Ensrud, K. E., Ewing, S. K., Stone, K. L., Cauley, J. A., Bowman, P. J., Cummings, S. R., & for the Study of Osteoporotic Fractures Research Group (2003) · Journal of the American Geriatrics Society · doi:10.1046/j.1532-5415.2003.51558.x · Cited by 336 · see citing works
Flagged first, then by citations
Cited by
Sorted by citations
Pathogenesis of osteoporosis: concepts, conflicts, and prospects
Raisz, L. G. (2005) · Journal of Clinical Investigation · doi:10.1172/jci27071 · Cited by 1,779 · see citing works
Self-citationPickhardt, P. J., Pooler, B. D., Lauder, T., del Rio, A. M., Bruce, R. J., & Binkley, N. (2013) · Annals of Internal Medicine · doi:10.7326/0003-4819-158-8-201304160-00003 · Cited by 954 · see citing works
Reciprocal regulation of bone and energy metabolism
Lee, N. K., & Karsenty, G. (2008) · Trends in Endocrinology & Metabolism · doi:10.1016/j.tem.2008.02.006 · Cited by 190 · see citing works
Hepatitis C virus infection and risk of osteoporosis: a meta-analysis
Wijarnpreecha, K., Thongprayoon, C., Panjawatanan, P., Phatharacharukul, P., & Ungprasert, P. (2017) · Saudi Journal of Gastroenterology · doi:10.4103/sjg.sjg_452_16 · Cited by 29 · see citing works
Utility of C-terminal Telopeptide in Evaluating Levothyroxine Replacement Therapy-Induced Bone Loss
Christy, A. L., D'Souza, V., Babu, R. P., Takodara, S., Manjrekar, P., Hegde, A., & Rukmini, M. S. (2014) · Biomarker Insights · doi:10.4137/bmi.s13965 · Cited by 14 · see citing works
- Authors
- Raisz, L. G.
- Affiliations
- UConn Health (US)
- Corresponding author
- Raisz, Lawrence G.
- Venue
- New England Journal of Medicine
- Publisher
- Massachusetts Medical Society
- Published
- 2005-07-14
- Volume
- 353
- Issue
- 2
- Pages
- 164-171
- ISSN
- 0028-4793 (ISSN-L)
- 1533-4406
- OpenAlex
- W2072662858
- Cited by
- 262
- References
- 4
- Citations by year
- 2026: 4 · 2025: 6 · 2024: 5 · 2023: 7 · 2022: 7 · 2021: 7 · 2020: 10 · 2019: 6 · 2018: 6 · 2017: 4 · 2016: 9 · 2015: 12 · 2014: 9 · 2013: 14 · 2012: 13
- FWCI
- 5.23
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- New England Journal of Medicine (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Orthopedics and Sports Medicine › Bone health and osteoporosis research
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Menopause: Health Impacts and Treatments
- Health Sciences › Medicine › Pathology and Forensic Medicine › Vitamin D Research Studies
- Keywords
- osteoporosis screening, bone densitometry, postmenopausal women, menopause, hormone replacement therapy, calcium supplementation, fracture risk, physician counseling
- MeSH terms
- Female, Fractures, Spontaneous, Humans, Middle Aged, Risk Factors, Tomography, X-Ray Computed, Absorptiometry, Photon, Bone Density, Osteoporosis, Postmenopausal, Practice Guidelines as Topic, Patient Selection, Fractures, Bone
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
