The DOI matches its Crossref record; 26 of the 26 references it cites were found in a registry or an index.
Alpha1-Antitrypsin Deficiency
Abstract
A 60-year-old white man presents for evaluation of progressive dyspnea. He is a former smoker with a 20-pack-year smoking history and a 10-year history of chronic obstructive pulmonary disease (COPD). There is no family history of COPD. Severe airflow obstruction is seen on spirometry, with a forced expiratory volume in 1 second that is 40% of the predicted value. Should he be evaluated for alpha1-antitrypsin (AAT) deficiency? If AAT deficiency is documented, how should his case be managed?
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Cites
PAUWELS, R. A., BUIST, A. S., CALVERLEY, P. M. A., JENKINS, C. R., & HURD, S. S. (2001) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/ajrccm.163.5.2101039 · Cited by 6,587
A randomized trial comparing lung-volume-reduction surgery with medical therapy for severe emphysema
(2003) · New England Journal of Medicine · doi:10.1056/nejmoa030287 · Cited by 2,071
(2003) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/rccm.168.7.818 · Cited by 911
Liver Disease in Alpha1-Antitrypsin Deficiency Detected by Screening of 200,000 Infants
Sveger, T. (1976) · New England Journal of Medicine · doi:10.1056/nejm197606102942404 · Cited by 796
Replacement Therapy for Alpha1-Antitrypsin Deficiency Associated with Emphysema
Wewers, M. D., Casolaro, M. A., Sellers, S. E., Swayze, S. C., McPhaul, K. M., Wittes, J. T., & Crystal, R. G. (1987) · New England Journal of Medicine · doi:10.1056/nejm198704233161704 · Cited by 641
A Randomized Clinical Trial of α 1 -Antitrypsin Augmentation Therapy
DIRKSEN, A., DIJKMAN, J. H., MADSEN, F., STOEL, B., HUTCHISON, D. C. S., ULRIK, C. S., SKOVGAARD, L. T., KOK-JENSEN, A., RUDOLPHUS, A., SEERSHOLM, N., et al. (1999) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/ajrccm.160.5.9901055 · Cited by 498
Alpha1-Antitrypsin Deficiency — A Model for Conformational Diseases
Carrell, R. W., & Lomas, D. A. (2002) · New England Journal of Medicine · doi:10.1056/nejmra010772 · Cited by 448
Survival and FEV 1 Decline in Individuals with Severe Deficiency of α 1 -Antitrypsin
The Alpha-1-Antitrypsin Deficiency Registry Study Group (1998) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/ajrccm.158.1.9712017 · Cited by 435
Worldwide Racial and Ethnic Distribution of α1-Antitrypsin Deficiency
de Serres, F. J. (2002) · Chest · doi:10.1378/chest.122.5.1818 · Cited by 394
Seersholm, N., Wencker, M., Banik, N., Viskum, K., Dirksen, A., Kok-Jensen, A., & Konietzko, N. (1997) · European Respiratory Journal · doi:10.1183/09031936.97.10102260 · Cited by 308
Cited by
Martin, P., DiMartini, A., Feng, S., Brown, R., & Fallon, M. (2014) · Hepatology · doi:10.1002/hep.26972 · Cited by 1,045
Neutrophil Elastase, Proteinase 3, and Cathepsin G as Therapeutic Targets in Human Diseases
Korkmaz, B., Horwitz, M. S., Jenne, D. E., & Gauthier, F. (2010) · Pharmacological Reviews · doi:10.1124/pr.110.002733 · Cited by 870
Chronic obstructive pulmonary disease
Barnes, P. J., Burney, P. G. J., Silverman, E. K., Celli, B. R., Vestbo, J., Wedzicha, J. A., & Wouters, E. F. M. (2015) · Nature Reviews Disease Primers · doi:10.1038/nrdp.2015.76 · Cited by 734
Self-citationHancock, D. B., Eijgelsheim, M., Wilk, J. B., Gharib, S. A., Loehr, L. R., Marciante, K. D., Franceschini, N., van Durme, Y. M. T. A., Chen, T.-H., Barr, R. G., et al. (2010) · Nature Genetics · doi:10.1038/ng.500 · Cited by 632
Definition and Nomenclature of Chronic Obstructive Pulmonary Disease: Time for Its Revision
Celli, B., Fabbri, L., Criner, G., Martinez, F. J., Mannino, D., Vogelmeier, C., Montes de Oca, M., Papi, A., Sin, D. D., Han, M. K., et al. (2022) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/rccm.202204-0671pp · Cited by 518
Metadata
- Authors
- Silverman, E. K., & Sandhaus, R. A.
- Venue
- New England Journal of Medicine
- Publisher
- Massachusetts Medical Society
- Published
- 2009-06-25
- Volume
- 360
- Issue
- 26
- Pages
- 2749-2757
- ISSN
- 0028-4793 (ISSN-L)
- 1533-4406
- OpenAlex
- W168858771
- Cited by
- 416
- References
- 26
- FWCI
- 20.07
- Type
- journal article
- Language
- en
- Open access
- closed
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Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
