The DOI matches its Crossref record; 76 of the 76 references it cites were found in a registry or an index.
Extracorporeal Membrane Oxygenation for ARDS in Adults
Abstract
A 41-year-old woman presents with severe community-acquired pneumococcal pneumonia. Chest radiography reveals diffuse bilateral infiltrates, and hypoxemic respiratory failure develops despite appropriate antibiotic therapy. She is intubated and mechanical ventilation is initiated with a volume- and pressure-limited approach for the acute respiratory distress syndrome (ARDS). Over the ensuing 24 hours, her partial pressure of arterial oxygen (Pao2) decreases to 40 mm Hg, despite ventilatory support with a fraction of inspired oxygen (Fio2) of 1.0 and a positive end-expiratory pressure (PEEP) of 20 cm of water. She is placed in the prone position and a neuromuscular blocking agent is administered, without improvement in her Pao2. An intensive care specialist recommends the initiation of extracorporeal membrane oxygenation (ECMO).
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“In critical care, where life-altering decisions must be made rapidly, decisional conflict may be particularly pronounced4.”
From Decisional conflict among Chinese family caregivers prior to ECMO initiation: a cross-sectional study (2025) · cites this paper as [4]
Citations
Cites
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A Multicenter, Randomized, Controlled Clinical Trial of Transfusion Requirements in Critical Care
Hébert, P. C., Wells, G., Blajchman, M. A., Marshall, J., Martin, C., Pagliarello, G., Tweeddale, M., Schweitzer, I., & Yetisir, E. (1999) · New England Journal of Medicine · doi:10.1056/nejm199902113400601 · Cited by 5,187
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Comparison of Two Fluid-Management Strategies in Acute Lung Injury
(2006) · New England Journal of Medicine · doi:10.1056/nejmoa062200 · Cited by 3,538
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Functional Disability 5 Years after Acute Respiratory Distress Syndrome
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Neuromuscular Blockers in Early Acute Respiratory Distress Syndrome
Papazian, L., Forel, J.-M., Gacouin, A., Penot-Ragon, C., Perrin, G., Loundou, A., Jaber, S., Arnal, J.-M., Perez, D., Seghboyan, J.-M., et al. (2010) · New England Journal of Medicine · doi:10.1056/nejmoa1005372 · Cited by 2,432
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Cited by
Sorted by citations
Extracorporeal Membrane Oxygenation for Severe Acute Respiratory Distress Syndrome
Combes, A., Hajage, D., Capellier, G., Demoule, A., Lavoué, S., Guervilly, C., Da Silva, D., Zafrani, L., Tirot, P., Veber, B., et al. (2018) · New England Journal of Medicine · doi:10.1056/nejmoa1800385 · Cited by 2,380
Self-citationVentilator-Induced Lung Injury
Slutsky, A. S., & Ranieri, V. M. (2013) · New England Journal of Medicine · doi:10.1056/nejmra1208707 · Cited by 2,330
The acute respiratory distress syndrome
Matthay, M. A., Ware, L. B., & Zimmerman, G. A. (2012) · Journal of Clinical Investigation · doi:10.1172/jci60331 · Cited by 1,706
Schmidt, M., Bailey, M., Sheldrake, J., Hodgson, C. L., Aubron, C., Rycus, P. T., Scheinkestel, C. D., Cooper, D. J., Brodie, D., Pellegrino, V. A., et al. (2014) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/rccm.201311-2023oc · Cited by 830
Self-citationBarbaro, R. P., Odetola, F. O., Kidwell, K., Paden, M. L., Bartlett, R. H., Davis, M. M., & Annich, G. M. (2015) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/rccm.201409-1634oc · Cited by 752
Metadata
- Authors
- Brodie, D., & Bacchetta, M.
- Affiliations
- NewYork–Presbyterian Hospital (US)
- Venue
- New England Journal of Medicine
- Publisher
- Massachusetts Medical Society
- Published
- 2011-11-17
- Volume
- 365
- Issue
- 20
- Pages
- 1905-1914
- ISSN
- 0028-4793 (ISSN-L)
- 1533-4406
- OpenAlex
- W2037145800
- Cited by
- 836
- References
- 76
- Citations by year
- 2026: 19 · 2025: 33 · 2024: 36 · 2023: 36 · 2022: 42 · 2021: 64 · 2020: 65 · 2019: 67 · 2018: 58 · 2017: 81 · 2016: 89 · 2015: 61 · 2014: 83 · 2013: 56 · 2012: 40
- FWCI
- 9.50
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- New England Journal of Medicine (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Pulmonary and Respiratory Medicine › Respiratory Support and Mechanisms
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Mechanical Circulatory Support Devices
- Health Sciences › Medicine › Pulmonary and Respiratory Medicine › Neonatal Respiratory Health Research
- Keywords
- extracorporeal membrane oxygenation, acute respiratory distress syndrome, community-acquired pneumonia, pneumococcal pneumonia, hypoxemic respiratory failure, mechanical ventilation, prone positioning, neuromuscular blockade, adult patients
- MeSH terms
- Adult, Hypoxia, Female, Humans, Pneumonia, Pneumococcal, Respiratory Distress Syndrome, Extracorporeal Membrane Oxygenation, Practice Guidelines as Topic, Community-Acquired Infections
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