Cited by 270Diabetes Management and ResearchDiabetes Management and EducationDiabetes Treatment and Management

The DOI matches its Crossref record; 49 of the 50 references it cites were found in a registry or an index.

Insulin-Pump Therapy for Type 1 Diabetes Mellitus

Pickup, John C.·2012·New England Journal of Medicine

Open this paper in CoChat — free account

Abstract

A 39-year-old man with type 1 diabetes mellitus is referred for consideration of insulin-pump therapy because of poor glycemic control and episodes of severe hypoglycemia. Insulin-pump therapy can improve blood glucose control but requires a willing and motivated patient.

Integrity signals

Registry

Crossref · 10.1056/nejmct1113948

Cites

49 of 49 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Claims the paper makes

This paper’s full text isn’t openly available, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

The Effect of Intensive Treatment of Diabetes on the Development and Progression of Long-Term Complications in Insulin-Dependent Diabetes Mellitus
(1993) · New England Journal of Medicine · doi:10.1056/nejm199309303291401 · Cited by 24,667
Standards of Medical Care in Diabetes—2012
(2012) · Diabetes Care · doi:10.2337/dc12-s011 · Cited by 2,240
Hypoglycemia in Diabetes
Cryer, P. E., Davis, S. N., & Shamoon, H. (2003) · Diabetes Care · doi:10.2337/diacare.26.6.1902 · Cited by 1,160
Training in flexible, intensive insulin management to enable dietary freedom in people with type 1 diabetes: dose adjustment for normal eating (DAFNE) randomised controlled trial
(2002) · BMJ · doi:10.1136/bmj.325.7367.746 · Cited by 916
Severe hypoglycaemia and glycaemic control in Type 1 diabetes: meta‐analysis of multiple daily insulin injections compared with continuous subcutaneous insulin infusion
Pickup, J. C., & Sutton, A. J. (2008) · Diabetic Medicine · doi:10.1111/j.1464-5491.2008.02486.x · Cited by 630
Self-citation
Continuous subcutaneous insulin infusion: an approach to achieving normoglycaemia.
Pickup, J. C., KEEN, H., PARSONS, J. A., & Alberti, K. G. M. M. (1978) · BMJ · doi:10.1136/bmj.1.6107.204 · Cited by 563
Self-citation
Insulin Pump Therapy
Weissberg-Benchell, J. A., Antisdel, J. E., & SESHADRI, R. M. (2003) · Diabetes Care · doi:10.2337/diacare.26.4.1079 · Cited by 549
Glycaemic control in type 1 diabetes during real time continuous glucose monitoring compared with self monitoring of blood glucose: meta-analysis of randomised controlled trials using individual patient data
Pickup, J. C., Freeman, S. C., & Sutton, A. J. (2011) · BMJ · doi:10.1136/bmj.d3805 · Cited by 541
Self-citation
Outpatient Insulin Therapy in Type 1 and Type 2 Diabetes Mellitus: Scientific Review
DeWitt, D. E., & Hirsch, I. B. (2003) · JAMA · doi:10.1001/jama.289.17.2254 · Cited by 502
Glycaemic control with continuous subcutaneous insulin infusion compared with intensive insulin injections in patients with type 1 diabetes: meta-analysis of randomised controlled trials
Pickup, J. C., Mattock, M., & Kerry, S. (2002) · BMJ · doi:10.1136/bmj.324.7339.705 · Cited by 481
Self-citation

Show all 50 references

Research works printed but not linked: 1

Misso ML, 2010, Cochrane Database Syst Rev, 1, CD005103

Sorted by citations

Items 201–270 of 270

Cutting-edge nanotechnology in diabetes care: metamorphosing diagnostics and treatment strategies
Sarkhel, S., Shuvo, S. M., Sarkar, T., GHOSH, A., Kapat, P., & Biswas, R. (2026) · Future Journal of Pharmaceutical Sciences · doi:10.1186/s43094-026-00941-8 · Cited by 2
Auf dem Weg zum „Closed-loop“-System
Thomas, A., Heinemann, L., & Freckmann, G. (2014) · Der Diabetologe · doi:10.1007/s11428-013-1127-y · Cited by 1
Real-Time Continuous Glucose Monitoring in Children and Adolescents
Battelino, T., Dovč, K., & Bratina, N. (2014) · Frontiers in diabetes · doi:10.1159/000363481 · Cited by 1
Launch of the ABCD Insulin Pump Network UK
Wilmot, E. G., Hammond, P. J., & Gregory, R. (2016) · British Journal of Diabetes · doi:10.15277/bjd.2016.061 · Cited by 1
How insulin analogues can benefit patients
Dokken, B. B. (2013) · The Nurse Practitioner · doi:10.1097/01.npr.0000425828.67564.10 · Cited by 1
Anlage einer Insulinpumpe
Biester, T., Biester, S., Kordonouri, O., & Danne, T. (2017) · DMW - Deutsche Medizinische Wochenschrift · doi:10.1055/s-0042-119235 · Cited by 1
Continuous subcutaneous insulin infusion in patients with type 1 disease
Meetoo, D. D., Wong, L., & Fatani, T. (2017) · British Journal of Healthcare Management · doi:10.12968/bjhc.2017.23.7.313 · Cited by 1
A Retrospective Review of the Clinical Characteristics and Blood Glucose Data from Cellnovo System Users using Data Collected from the Cellnovo Online Platform
Hautier-Suply, O., Friedmann, Y., & Shapley, J. (2018) · touchREVIEWS in Endocrinology · doi:10.17925/ee.2018.14.1.30 · Cited by 1
Machine Learning Based Automated Blood Sugar Regulatory System
Suhas, K. K., Kalyani, G., & Surya, M. V. S. S. (2024) · International Conference on Sustainable Computing and Smart Systems (ICSCSS) · doi:10.1109/icscss60660.2024.10625421 · Cited by 1
The Importance of the Bolus Calculator Use for Improving Glycemic Control in Patients on the Insulin Pump Therapy
Carić, B., Lalic, K. S., Marin, S., Stošić, L., & Popović‐Pejičić, S. (2017) · Scripta Medica · doi:10.18575/msrs.sm.e.17.07 · Cited by 1
Comparing Lifestyle Convenience of Multiple Daily Injection and Continuous Subcutaneous Insulin Infusion
Nishio, I. (2017) · Open Journal of Nursing · doi:10.4236/ojn.2017.712098 · Cited by 1
Development of physiological metabolic models in diabetes based on data mining techniques
Georga, E. I. (2019) · University of Ioannina · doi:10.26268/heal.uoi.1420 · Cited by 1
Insulin Pumps
Pickup, J. C. (2018) · Endocrinology · doi:10.1007/978-3-319-27317-4_22-1 · Cited by 1
Self-citation
Advances in Insulin Therapy
Canciani, G. N., Stewart, Z. A., & Murphy, H. R. (2017) · Wiley eBooks · doi:10.1002/9781119043805.ch16 · Cited by 1
Inseltransplantation als Therapieoption bei Diabetes mellitus Typ 1: Für wen, mit welchem Ziel, mit welchem Erfolg?
Ludwig, B. (2014) · Journal für Kardiologie (Krause & Pachernegg GmbH)
Modern technologies for glucose monitoring and insulin replacement
Leong, C. H. M., Velusamy, A., & Choudhary, P. (2014) · Medicine · doi:10.1016/j.mpmed.2014.09.004
Continuous subcutaneous insulin infusion versus multiple dose insulin
Gupta, Y., & Kalra, S. (2014) · Sri Lanka Journal of Diabetes Endocrinology and Metabolism · doi:10.4038/sjdem.v4i1.7249
In search of improved glucose control: helping the patient decide between insulin injections and infusion pump therapy
Roe, E. D., Woo, J. S., & Raskin, P. (2012) · Diabetes Management · doi:10.2217/dmt.12.49
Insulin, Other Hypoglycaemic Drugs, and Glucagon
Bavec, A. (2014) · Side effects of drugs annual · doi:10.1016/b978-0-444-63407-8.00042-3
Self-Monitoring in Diabetes: When and How Much?
Pintaudi, B., & Nicolucci, A. (2014) · Frontiers in diabetes · doi:10.1159/000363474
Clinical management of type 1 diabetes
Iqbal, A., & Heller, S. R. (2015) · doi:10.1002/9781119121725.ch8
Avaliação de diabeticos após três meses de uso de sistema de infusão contínua de insulina, dispensado de forma protocolada pelo ambulatório de referência do Hospital Regional de Taguatinga
Miranda, L. G. (2013) · Americanae (AECID Library)
Insulin Pump Therapy in Non-Pregnant Hospitalized Adults: A Review of the Literature
Gibson, J. M. (2014) · Journal of Nursing & Care · doi:10.4172/2167-1168.1000199
Comparing the Self-care of Type 1 Diabetes Patients who experienced both Multiple Dose Injection and Insulin Pump Therapies; A case study and Recommendation for Practice
Nishio, I., Chujo, M., & Yamao, M. (2015) · International Journal of Nursing & Clinical Practices · doi:10.15344/2394-4978/2015/151
Intensive insulin therapy
Trujillo, J. M. (2013) · Elsevier eBooks · doi:10.1016/b978-1-4557-4975-1.00012-7
Recommendation System: A Contribution to Glycaemia Excursion Identification
Lhotská, L., Burša, M., Huptych, M., & Štechová, K. (2016) · World Congress on Medical Physics and Biomedical Engineering, September 7 - 12, 2009, Munich, Germany · doi:10.1007/978-3-319-32703-7_226
Insulin Pump Termination in Adult Patients
Cesakova, V. C. H., & Jankovec, J. B. Z. (2015) · Journal of Diabetes & Metabolism · doi:10.4172/2155-6156.1000606
Basal rate tests (24‐hour fasts) performed in type‐1 diabetic subjects with either absolute fasting or snacks containing negligible carbohydrate amounts result in similar glucose profiles: A randomized controlled prospective trial
Haase, M., Kahle, M., Janert, M., Meier, J. J., & Nauck, M. A. (2017) · Diabetes Obesity and Metabolism · doi:10.1111/dom.12868
Supporting patients with type 1 diabetes
Phillips, A. (2017) · Practice Nursing · doi:10.12968/pnur.2017.28.1.28
Neuropsychological Functioning And Stress Reactivity In Type 1 Diabetes Mellitus
Purdom, C. L. (2013)
Epidemiological characterization of diabetic patients on therapy with continuous subcutaneous insulin infusion and continuous glucose monitoring in real time
Aristizábal, N., Ramírez, Á., Hincapié-García, J. A., Laiton, E., Aristizábal, C., Cuesta, D., Monsalve, C., Hincapié, G., Zapata, E., Abad, V., et al. (2015) · Endocrinología y Nutrición (English Edition) · doi:10.1016/j.endoen.2015.11.006
Spatiotemporal and Mechanistic Analysis of Nkx2.2 Function in the Pancreatic Islet
Churchill, A. J. (2016) · doi:10.7916/d84m94n2
Localized Tolerance and Development of an Alternative Transplant Site to Treat Type 1 Diabetes
Skoumal, M. (2017) · Deep Blue (University of Michigan)
Development of a boronic acid sensor-based glucose-responsive nanoparticulate insulin delivery system
Siddiqui, N. A. (2017) · Nottingham ePrints (University of Nottingham)
Optimizing Insulin Pump Therapy: Advanced Bolus Options
Carić, B., Vuković, B., & Lalic, K. S. (2019) · World Congress on Medical Physics and Biomedical Engineering, September 7 - 12, 2009, Munich, Germany · doi:10.1007/978-3-030-17971-7_50
Anlage einer Insulinpumpe
Biester, T., Biester, S., Kordonouri, O., & Danne, T. (2019) · Diabetologie und Stoffwechsel · doi:10.1055/a-0895-7894
Vergleich von zwei Protokollen zur Durchführung eines Fastentages zur Überprüfung der basalen Insulinsubstitution bei Typ-1-Diabetes: Konsequentes Fasten im Vergleich zur Erlaubnis einer Kost mit vernachlässigbarem Kohlenhydrat- und Kaloriengehalt
Haase, M. (2018) · doi:10.53846/goediss-6772
小児1型糖尿病治療～30年で変わったこと・変わらないこと～
具純, 高. (2020) · doi:10.24616/jaden.24.1_57
A comparison of pathogenesis of Diabetes in China and the United States
Wen, H. (2021) · E3S Web of Conferences · doi:10.1051/e3sconf/202123302018
Using the Novel Approach of an Artificial Pancreas to Manage Type 1 Diabetes Mellitus in Pregnancy
Lefkovits, Y. R., Stewart, Z., & Murphy, H. R. (2019) · European Medical Journal · doi:10.33590/emj/10312967
“Closed Loop” Insulin Delivery
Hovorka, R., & Boughton, C. K. (2022) · doi:10.1093/med/9780198870197.003.0264
Insulin Delivery Hardware: Pumps and Pens
Lal, R., & Leelarathna, L. (2022) · Diabetes Technology & Therapeutics · doi:10.1089/dia.2022.2502
Insulin Pumps
Pickup, J. C. (2018) · Endocrinology · doi:10.1007/978-3-319-45015-5_22
Self-citation
Antiglycemic Agents
Chang, L., & Kim, M. I. (2016) · Hospital Medicine Clinics · doi:10.1016/j.ehmc.2016.05.004
Comparison between a multiple daily insulin injection regimen (basal once-daily glargine plus mealtime lispro) and continuous subcutaneous insulin infusion (lispro) using continuous glucose monitoring in metabolically optimized type 1 diabetes patients: A randomized open-labelled parallel study
Ruiz-de-Adana, M. S., Dominguez-Lopez, M.-E., González-Molero, I., Machado, A., Martin, V., Cardona, I., de la Higuera, M., Tapia, M. J., Soriguer, F., Ortiz, M. T. A., et al. (2016) · Medicina Clínica (English Edition) · doi:10.1016/j.medcle.2015.09.006
Endocrine Summary
McMahon, G. T. (2014) · doi:10.1093/med/9780199358274.003.0056
Type 1 diabetes: technology and transplants
FRCP, D. L. M. (2017) · Wiley eBooks · doi:10.1002/9781119052210.ch8
Devices
Carty, D. (2022) · Wiley eBooks · doi:10.1002/9781119785033.ch10
Insulin
Slater, L., STUCKEY, S. L., & Chandra, R. V. (2022) · Springer eBooks · doi:10.1007/978-3-031-08774-5_60
The Role of Synthetic and Natural Biomaterials in Modulating the Autoimmune Response
Pal, S., Sofi, H. S., Azmi, L., Khan, N. A., Majeed, S., Beigh, M. A., & Sheikh, F. A. (2023) · Springer eBooks · doi:10.1007/978-981-99-2119-5_1
Einstellung zur Insulinpumpentherapie bei Menschen mit Typ-1-Diabetes sechs Monate nach Umstellung im Vergleich zu mehrfach täglichen Insulininjektionen – Eine Beobachtungstudie
Hermanns, N., Ehrmann, D., Kulzer, B., Kalt, L., & Seufert, J. (2024) · Diabetologie und Stoffwechsel · doi:10.1055/a-2280-8966
Insulin Pumps
Cengiz, E. (2019) · doi:10.2337/9781580406932.part1_ch03
Engineered promoter-free insulin-secreting cells provide closed-loop glycemic control
Li, Y., He, C., Younis, D. A., Ni, C., Liu, R., Sun, Z., Lin, H., Wang, Y., Zhu, P., Xiao, Z., et al. (2025) · Life Sciences · doi:10.1016/j.lfs.2025.123587
No evidence from euglycaemic–hyperinsulinaemic clamp studies for greater insulin sensitivity in adults with type 1 diabetes using insulin pump versus multiple daily insulin injections—Post hoc meta‐analysis
Januszewski, A. S., SNAITH, J. R., Grzelka‐Woźniak, A., Simonsen, J. R., Sachithanandan, N., Ward, G. M., O'Neal, D. N., Gordin, D., Thorn, L. M., Groop, P., et al. (2025) · Diabetes Obesity and Metabolism · doi:10.1111/dom.16487
A Developed Design of Low-Cost Insulin Pump for Automated Insulin Delivery (Aid) System
Elshorbagy, K. A., Abuouf, Y., & Sharaf, M. Z. (2025) · International Telecommunications Conference (ITC-Egypt) · doi:10.1109/itc-egypt66095.2025.11186693
Technological innovations in the treatment of diabetes over the last decade
Sonia, T. A., & Sharma, C. P. (2025) · Elsevier eBooks · doi:10.1016/b978-0-443-30272-5.00011-1
Comparative Study of Glycemic Control and Treatment Satisfaction in Patients With Type 1 Diabetes on Sensor-Augmented Insulin Pump, Insulin Pump, and Multiple Daily Insulin Injections: A Cross-Sectional Study
Alshahrani, A. A., & Mutairi, F. (2025) · Cureus · doi:10.7759/cureus.94771
Age-Specific Basal Rate Profile Characteristics at Initiation of Insulin Pump Therapy
GHIMPEŢEANU, G., Román, G., Ciobanu, D. M., & Alionescu, A. (2014) · World Congress on Medical Physics and Biomedical Engineering, September 7 - 12, 2009, Munich, Germany · doi:10.1007/978-3-319-07653-9_14
Survival of patients with type 1 diabetes on renal replacement therapy
Helve, J. (2014) · Työväentutkimus Vuosikirja
Additional file 4 of Humanistic burden of pediatric type 1 diabetes on children and informal caregivers: systematic literature reviews
Allen, V. D., Mahieu, A., Kasireddy, E., Shouman, W., Pourrahmat, M.-M., Collet, J.-P., & Cherkas, A. (2024) · Figshare · doi:10.6084/m9.figshare.26696133
Additional file 3 of Humanistic burden of pediatric type 1 diabetes on children and informal caregivers: systematic literature reviews
Allen, V. D., Mahieu, A., Kasireddy, E., Shouman, W., Pourrahmat, M.-M., Collet, J.-P., & Cherkas, A. (2024) · Figshare · doi:10.6084/m9.figshare.26696130
Additional file 1 of Humanistic burden of pediatric type 1 diabetes on children and informal caregivers: systematic literature reviews
Allen, V. D., Mahieu, A., Kasireddy, E., Shouman, W., Pourrahmat, M.-M., Collet, J.-P., & Cherkas, A. (2024) · Figshare · doi:10.6084/m9.figshare.25459478
Additional file 2 of Humanistic burden of pediatric type 1 diabetes on children and informal caregivers: systematic literature reviews
Allen, V. D., Mahieu, A., Kasireddy, E., Shouman, W., Pourrahmat, M.-M., Collet, J.-P., & Cherkas, A. (2024) · Figshare · doi:10.6084/m9.figshare.25459646
Bombas de insulina (BI)
Proietti, A., & Grosembacher, L. (2015) · Revista del Hospital Italiano de Buenos Aires · doi:10.51987/rev.hosp.ital.b.aires.v35i2.731
Protective IFIH1 variant reduces immune-mediated islet stress and dysfunction in a type 1 diabetes genetic backgroundPreprint
Veronese-Paniagua, D., Banks, C. E., Bradley, K., Mukherjee, N., Gale, S. E., Hinshaw, K. E., Meacham, A. M., Iwaloye, O. F., Tse, H. M., Mathews, C. E., et al. (2025) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.64898/2025.12.30.697107
Causal mediation pathways in continuous postprandial glucose monitoring for type 1 diabetes patients
Hilligoss, S., & Qu, A. (2026) · npj Metabolic Health and Disease · doi:10.1038/s44324-026-00127-z
Mitochondrial development and remodeling occur at pancreatic progenitor stage during induction of stem cell-derived islet organoids
Diané, A., Mu-u-min, R., Al-Shukri, N. A., Nour‐Eldine, W., & Al-Siddiqi, H. (2026) · Frontiers in Endocrinology · doi:10.3389/fendo.2026.1795738 · Cited by 1
Microfluidic transistor as a pressure-tunable flow regulatorPreprint
Musharaf, H. M., Zhang, J., & Nguyen, N. (2026) · SSRN Electronic Journal · doi:10.2139/ssrn.7151903
Role of vasular endothelial growth factor (VEGF) in diabetic complication
Kumar, N., Kumar, S., Sharma, R. K., Kumar, B., Sharma, P., Jain, A., Debnath, A., Sharma, P., & Verma, S. (2026) · AIP conference proceedings · doi:10.1063/5.0286245
Interpretation of Long-Term Clinical Diabetes Data and Prediction of Glycemic Control Based on Data Mining Techniques
Georga, E. I., Protopappas, V. C., Bellos, C. V., Makriyiannis, D., & Fotiadis, D. I. (2013) · World Congress on Medical Physics and Biomedical Engineering, September 7 - 12, 2009, Munich, Germany · doi:10.1007/978-3-319-03005-0_80

Authors: Pickup, J. C.
Affiliations: Guy's Hospital (GB)
Corresponding author: Pickup, John C.
ORCID: Pickup, John C.
Venue: New England Journal of Medicine
Publisher: Massachusetts Medical Society
Published: 2012-04-26
Volume: 366
Issue: 17
Pages: 1616-1624
ISSN: 0028-4793 (ISSN-L)
1533-4406
DOI: 10.1056/nejmct1113948
OpenAlex: W1973697640
Cited by: 270
References: 50
Citations by year: 2026: 5 · 2025: 9 · 2024: 12 · 2023: 11 · 2022: 15 · 2021: 15 · 2020: 13 · 2019: 21 · 2018: 21 · 2017: 34 · 2016: 25 · 2015: 32 · 2014: 29 · 2013: 20 · 2012: 8
FWCI: 3.91
Type: journal article
Language: en
Open access: closed
Locations: New England Journal of Medicine (publishedVersion)
PubMed (publishedVersion)
Research Portal (King's College London) (submittedVersion)
Topics: Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes Management and Research
Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes Management and Education
Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes Treatment and Management
Keywords: insulin pump therapy, type 1 diabetes, glycemic control, hypoglycemia, patient motivation
MeSH terms: Adult, Blood Glucose, Diabetes Mellitus, Type 1, Humans, Hypoglycemic Agents, Insulin, Insulin Infusion Systems, Male, Practice Guidelines as Topic, Overweight

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

Insulin-Pump Therapy for Type 1 Diabetes Mellitus

Abstract

Overview

Integrity signals

Verification

Claims the paper makes

Claims other papers make about this one

Citations

Cites

Cited by

Related

Metadata

Record

About these checks