Cited by 23Food Allergy and Anaphylaxis ResearchDrug-Induced Adverse ReactionsEosinophilic Esophagitis

Preventing peanut allergy through early consumption–ready for prime time?

Gruchalla, Rebecca S., Sampson, Hugh A.·2015·New England Journal of Medicine

Abstract

Kids can't take peanut butter to school. Some airlines no longer serve peanuts because of fear of anaphylaxis among passengers. These developments are just the tip of the iceberg as the prevalence of peanut allergy among children continues to increase worldwide, especially in westernized countries. In the United States alone, the prevalence has more than quadrupled in the past 13 years, growing from 0.4% in 1997 to 1.4% in 20081 to more than 2% in 2010.2 Peanut allergy has become the leading cause of anaphylaxis and death related to food allergy in the United States.3 In 2000, largely in response . . .

Integrity signals

Registry

Crossref · 10.1056/nejme1500186

Cites

9 of 9 references verified0 citation errors · 0 not checkable

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  • There is increasing evidence on the tolerance hypothesis in the etiology of food allergy, in which a clinical trial has shown that early consumption of peanuts can reduce the development of peanut allergy.

    “Interestingly, there is increasing evidence on this tolerance hypothesis in the etiology of food allergy in which a clinical trial has shown that early consumption of peanuts can reduce the development of peanut allergy (138, 139).”

    From Epidemiology of Asthma in Children and Adults (2019) · cites this paper as [139]

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Authors
Gruchalla, R. S., & Sampson, H. A.
Affiliations
  • The University of Texas Southwestern Medical Center (US)
  • Icahn School of Medicine at Mount Sinai (US)
Venue
New England Journal of Medicine
Published
2015-02-26
Volume
372
Issue
9
Pages
875-877
ISSN
  • 0028-4793 (ISSN-L)
  • 1533-4406
OpenAlex
W1994238541
Cited by
23
References
9
Citations by year
2026: 1 · 2020: 1 · 2019: 1 · 2017: 6 · 2016: 6 · 2015: 8
Type
journal article
Language
en
Open access
closed
Locations
  • New England Journal of Medicine (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Health Sciences › Medicine › Immunology and Allergy › Food Allergy and Anaphylaxis Research
  • Health Sciences › Medicine › Pharmacology › Drug-Induced Adverse Reactions
  • Health Sciences › Medicine › Surgery › Eosinophilic Esophagitis
Keywords
peanut allergy, early peanut introduction, peanut butter, food allergy prevention, anaphylaxis, allergy prevalence, children, allergen avoidance
MeSH terms
Diet, Female, Humans, Male, Arachis, Peanut Hypersensitivity

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