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The DOI matches its Crossref record; 39 of the 39 references it cites were found in a registry or an index.

Catheter Ablation for Atrial Fibrillation in Congestive Heart Failure

Open access
Hsu, Li-Fern, Jaïs, Pierre, Sanders, Prashanthan, Garrigue, Stéphane, Hocini, Mélèze, Sacher, Fréderic, Takahashi, Yoshihide, Rotter, Martin, Pasquié, Jean-Luc, Scavée, Christophe, Bordachar, Pierre, Clémenty, Jacques, Haïssaguerre, Michel·2004·New England Journal of Medicine

Abstract

BACKGROUND: Congestive heart failure and atrial fibrillation often coexist, and each adversely affects the other with respect to management and prognosis. We prospectively evaluated the effect of catheter ablation for atrial fibrillation on left ventricular function in patients with heart failure. METHODS: We studied 58 consecutive patients with congestive heart failure and a left ventricular ejection fraction of less than 45 percent who were undergoing catheter ablation for atrial fibrillation. We selected as controls 58 patients without congestive heart failure who were undergoing ablation for atrial fibrillation, matched according to age, sex, and classification of atrial fibrillation. We evaluated the patients' left ventricular function and dimensions, symptom score, exercise capacity, and quality of life at baseline and at months 1, 3, 6, and 12. RESULTS: After a mean (+/-SD) of 12+/-7 months, 78 percent of the patients with congestive heart failure and 84 percent of the controls remained in sinus rhythm (P=0.34) (69 percent and 71 percent, respectively, were in sinus rhythm without the administration of antiarrhythmic drugs). The patients with congestive heart failure had significant improvement in left ventricular function (increases in the ejection fraction and fractional shortening of 21+/-13 percent and 11+/-7 percent, respectively; P<0.001 for both comparisons), left ventricular dimensions (decreases in the diastolic and systolic diameters of 6+/-6 mm and 8+/-7 mm, respectively; P=0.03 and P<0.001, respectively), exercise capacity, symptoms, and quality of life. The ejection fraction improved significantly not only in patients without concurrent structural heart disease (24+/-10 percent, P<0.001) and those with inadequate rate control before ablation (23+/-10 percent, P<0.001), but also in those with coexisting heart disease (16+/-14 percent, P<0.001) and adequate rate control before ablation (17+/-15 percent, P<0.001). CONCLUSIONS: Restoration and maintenance of sinus rhythm by catheter ablation without the use of drugs in patients with congestive heart failure and atrial fibrillation significantly improve cardiac function, symptoms, exercise capacity, and quality of life.

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Metadata

Authors
Hsu, L.-F., Jaïs, P., Sanders, P., Garrigue, S., Hocini, M., Sacher, F., Takahashi, Y., Rotter, M., Pasquié, J.-L., Scavée, C., Bordachar, P., Clémenty, J., & Haïssaguerre, M.
Venue
New England Journal of Medicine
Published
2004-12-02
Volume
351
Issue
23
Pages
2373-2383
ISSN
  • 0028-4793 (ISSN-L)
  • 1533-4406
OpenAlex
W2348720246
Cited by
892
References
39
FWCI
42.96
Type
journal article
Language
en
Open access
bronze

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CoChat. (2026). Citation check: Catheter Ablation for Atrial Fibrillation in Congestive Heart Failure. https://app.cochat.ai/papers/10.1056/nejmoa041018
The paper
Hsu, L.-F., Jaïs, P., Sanders, P., Garrigue, S., Hocini, M., Sacher, F., Takahashi, Y., Rotter, M., Pasquié, J.-L., Scavée, C., Bordachar, P., Clémenty, J., & Haïssaguerre, M. (2004). Catheter Ablation for Atrial Fibrillation in Congestive Heart Failure. New England Journal of Medicine. https://doi.org/10.1056/nejmoa041018

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

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