Radiotherapy plus Concomitant and Adjuvant Temozolomide for Glioblastoma

Stupp, Roger, Mason, Warren P., van den Bent, Martin J., Weller, Michael, Fisher, Barbara, Taphoorn, Martin J.B., Belanger, Karl, Brandes, Alba A., Marosi, Christine, Bogdahn, Ulrich, Curschmann, Jürgen, Janzer, Robert C., Ludwin, Samuel K., Gorlia, Thierry, Allgeier, Anouk, Lacombe, Denis, Cairncross, J. Gregory, Eisenhauer, Elizabeth, Mirimanoff, René O.·2005·New England Journal of Medicine

DOI 10.1056/nejmoa043330

Cited by (1,070)

Items 801–900 of 1,070

Genome-wide CRISPR-Cas9 Screens Reveal Loss of Redundancy between PKMYT1 and WEE1 in Glioblastoma Stem-like Cells
Chad M. Toledo, Yu Ding, Pia Hoellerbauer, Ryan J. Davis, Ryan Basom, Emily J. Girard, Eunjee Lee, Philip D. Corrin, Traver Hart, Hamid Bolouri et al. · 2015 · Cell Reports
Glioma Stem Cells: Signaling, Microenvironment, and Therapy
Brandon D. Liebelt, Takashi Shingu, Xin Zhou, Jiangong Ren, Seula Shin, JIAN LI HU · 2016 · Stem Cells International
Dual targeting of glioblastoma with chimeric antigen receptor-engineered natural killer cells overcomes heterogeneity of target antigen expression and enhances antitumor activity and survival
Sabrina Genßler, Michael C. Burger, Congcong Zhang, Sarah Oelsner, Iris C. Mildenberger, Marlies Wagner, Jörg Steinbach, Winfried S. Wels · 2015 · OncoImmunology
STAT3-EMT axis in tumors: Modulation of cancer metastasis, stemness and therapy response
Mehrdokht Sadrkhanloo, Maliheh Entezari, Sima Orouei, Marzieh Ghollasi, Nikoo Fathi, Shamin Rezaei, Elahe Sadat Hejazi, Amirabbas Kakavand, Hamidreza Saebfar, Mehrdad Hashemi et al. · 2022 · Pharmacological Research
Irinotecan and temozolomide for Ewing sarcoma: The Memorial Sloan‐Kettering experience
Denise A. Casey, Leonard H. Wexler, Melinda S. Merchant, Alexander J. Chou, Pamela R. Merola, Anita P. Price, Paul A. Meyers · 2009 · Pediatric Blood & Cancer
Cytoreductive surgery of glioblastoma as the key to successful adjuvant therapies: new arguments in an old discussion
Walter Stummer, Martin J. van den Bent, Manfred Westphal · 2011 · Acta Neurochirurgica
Prognostic value of O6-methylguanine-DNA methyltransferase status in glioblastoma patients, assessed by five different methods
Lucie Karayan, Véronique Quillien, Joëlle Guilhot, Michel Wager, Gaëlle Fromont, Stéphan Saïkali, Amandine Etcheverry, Abderrahmane Hamlat, Delphine Loussouarn, L. Campion et al. · 2009 · Journal of Neuro-Oncology
Temozolomide: therapeutic limitations in the treatment of adult high-grade gliomas
Marc Charles Chamberlain · 2010 · Expert Review of Neurotherapeutics
Constitutive and TNFα-inducible expression of chondroitin sulfate proteoglycan 4 in glioblastoma and neurospheres: Implications for CAR-T cell therapy
Serena Pellegatta, Barbara Savoldo, Natalia Di Ianni, Cristina Corbetta, Yuhui Chen, Monica Patanè, Chuang Sun, Bianca Pollo, Soldano Ferrone, Francesco DiMeco et al. · 2018 · Science Translational Medicine
Loss of CX3CR1 increases accumulation of inflammatory monocytes and promotes gliomagenesis
Xi Feng, Frank Szulzewsky, Alexan I. Yerevanian, Zhihong Chen, David Heinzmann, Rikke Darling Rasmussen, Virginia Alvarez Garcia, Yeonghwan Kim, Bingcheng Wang, Ilaria Tamagno et al. · 2015 · Oncotarget
DNA damage response – A double-edged sword in cancer prevention and cancer therapy
Hui Tian, Zhen Gao, Huizhong Li, Baofu Zhang, Gang Wang, Qing Zhang, Dong‐Sheng Pei, Junnian Zheng · 2014 · Cancer Letters
Dual Targeting of the Autophagic Regulatory Circuitry in Gliomas with Repurposed Drugs Elicits Cell-Lethal Autophagy and Therapeutic Benefit
Ksenya Shchors, Aristea Massaras, Douglas Hanahan · 2015 · Cancer Cell
Oncological patterns of care and outcome for 952 patients with newly diagnosed glioblastoma in 2004
Luc Bauchet, Hélène Mathieu‐Daudé, Pascale Fabbro-Péray, Valérie Rigau, Michel Fabbro, Olivier Louis Chinot, L. Pallusseau, Charlotte Carnin, Karl Lainé, Aline Schlama et al. · 2010 · Neuro-Oncology
Systemic delivery of neutralizing antibody targeting CCL2 for glioma therapy
Xinmei Zhu, Mitsugu Fujita, Linda A. Snyder, Hideho Okada · 2010 · Journal of Neuro-Oncology
The Pan-Bcl-2 Inhibitor (−)-Gossypol Triggers Autophagic Cell Death in Malignant Glioma
Valerie Voss, Christian Senft, Verena Lang, Michael W. Ronellenfitsch, Joachim Peter Steinbach, Volker Seifert, Donat Kögel · 2010 · Molecular Cancer Research
Pediatric High Grade Glioma: a Review and Update on Tumor Clinical Characteristics and Biology
Jason Fangusaro · 2012 · Frontiers in Oncology
Radiation Therapy for Glioblastoma: American Society of Clinical Oncology Clinical Practice Guideline Endorsement of the American Society for Radiation Oncology Guideline
Erik P. Sulman, Nofisat Ismaila, Terri S. Armstrong, Christina I. Tsien, Tracy T. Batchelor, Tim F. Cloughesy, Evanthia Galanis, Mark R. Gilbert, Vinai Gondi, Mary Lovely et al. · 2017 · Journal of Clinical Oncology
Immunotherapy for Glioblastoma: Current Progress and Challenges
Miranda W. Yu, Daniela F. Quail · 2021 · Frontiers in Immunology
Early termination of ISRCTN45828668, a phase 1/2 prospective, randomized study of Sulfasalazine for the treatment of progressing malignant gliomas in adults
Pierre A. J. T. Robe, Didier Martin, Minh Nguyen-Khac, Maria Artesi, Manuel Deprez, Adelin Albert, Sophie Vanbelle, Stèphane Califice, Markus Bredel, Vincent Bours · 2009 · BMC Cancer
Ionizing radiations sustain glioblastoma cell dedifferentiation to a stem-like phenotype through survivin: possible involvement in radioresistance
Perrine Dahan, Judith Martinez-Gala, Caroline Delmas, Sylvie Monferran, Laure Malric, David Zentkowski, V. Lubrano, Christine Toulas, Elizabeth Cohen‐Jonathan Moyal, Anthony Lemarié · 2014 · Cell Death and Disease
In vivo assessment of high-grade glioma biochemistry using microdialysis: a study of energy-related molecules, growth factors and cytokines
Hani Joseph Marcus, Keri L.H. Carpenter, Stephen John Price, Peter J. Hutchinson · 2009 · Journal of Neuro-Oncology
Glioma-Initiating Cell Elimination by Metformin Activation of FOXO3 via AMPK
Atsushi Sato, Jun Sunayama, Masashi Okada, Eriko Watanabe, Shizuka Seino, Keita Shibuya, Kaori Suzuki, Yoshitaka Narita, Soichiro Shibui, Takamasa Kayama et al. · 2012 · Stem Cells Translational Medicine
Response Assessment in Neuro-Oncology Criteria for Gliomas: Practical Approach Using Conventional and Advanced Techniques
D.J. Leao, Patrick G Craig, Luís Filipe de Souza Godoy, Cláudia da Costa Leite, Bruno A. Policeni · 2019 · American Journal of Neuroradiology
Zika Virus Targets Glioblastoma Stem Cells through a SOX2-Integrin αvβ5 Axis
Zhe Zhu, Pinar Mesci, Jean A. Bernatchez, Ryan C. Gimple, Xiuxing Wang, Simon T. Schafer, Hiromi Inoue Wettersten, Sungjun Beck, Alex E. Clark, Qiulian Wu et al. · 2020 · Cell stem cell
Survival and quality of life analysis in glioblastoma multiforme with adjuvant chemoradiotherapy: a retrospective study
Soniya Mohammed, Dinesan Mathath, T Ajayakumar · 2022 · Reports of Practical Oncology & Radiotherapy
TGF-β signaling and its targeting for glioma treatment.
Jianfeng Han, Christopher A Alvarez-Breckenridge, Qi‐En Wang, Jianhua Yu · 2015 · PubMed Central
Management and survival rates in patients with glioma in China (2004–2010): a retrospective study from a single-institution
Pei Yang, Yongzhi Wang, Xiaoxia Peng, Gan You, Wei Zhang, Wei Yan, Zhaoshi Bao, Yinyan Wang, Xiaoguang Qiu, Tao Jiang · 2013 · Journal of Neuro-Oncology
Phase 2 study of concurrent radiotherapy and temozolomide followed by temozolomide and lomustine in the treatment of children with high-grade glioma: a report of the Children's Oncology Group ACNS0423 study
Regina I. Jakacki, Kenneth J. Cohen, Allen B. Buxton, Mark Krailo, Peter C. Burger, Marc K. Rosenblum, Daniel Jay Brat, Ronald L. Hamilton, Sandrah Proctor Eckel, Tianni Zhou et al. · 2016 · Neuro-Oncology
Targeted Delivery of Functionalized Upconversion Nanoparticles for Externally Triggered Photothermal/Photodynamic Therapies of Brain Glioblastoma
Yuan-Chung Tsai, Priya Vijayaraghavan, Wen‐Hsuan Chiang, Hsin‐Hung Chen, Te‐I Liu, Ming‐Yin Shen, Ayumu Omoto, Masao Kamimura, Kohei Soga, Hsin‐Cheng Chiu · 2018 · Theranostics
Increased compliance with tumor treating fields therapy is prognostic for improved survival in the treatment of glioblastoma: a subgroup analysis of the EF-14 phase III trial
Steven A. Toms, Chae‐Yong Kim, Garth Andrew Nicholas, Zvi Ram · 2018 · Journal of Neuro-Oncology
Drug Resistance in Glioblastoma: The Two Faces of Oxidative Stress
Christophe Olivier, Lisa Oliver, Lisenn Lalier-Bretaudeau, François M. Vallette · 2021 · Frontiers in Molecular Biosciences
Metabolic therapy: A new paradigm for managing malignant brain cancer
Thomas N. Seyfried, Roberto E. Flores, Angela M. Poff, Dominic P. D’Agostino, Purna Mukherjee · 2014 · Cancer Letters
Temozolomide: a novel treatment for pituitary carcinoma
Stephen Wong Lim, Hrayr K. Shahinian, Menahem M. Maya, William H. Yong, Anthony P. Heaney · 2006 · The Lancet Oncology
B7-H3-redirected chimeric antigen receptor T cells target glioblastoma and neurospheres
Dean Nehama, Natalia Di Ianni, Silvia Musio, Hongwei Du, Monica Patanè, Bianca Pollo, Gaetano Finocchiaro, James J.H. Park, Denise Dunn, Drake S. Edwards et al. · 2019 · EBioMedicine
Hypoxia: The Cornerstone of Glioblastoma
Marta Doménech, Ainhoa Hernández, Andrea Plaja, Eva Martinez‐Balibrea, Carmen Balañá · 2021 · International Journal of Molecular Sciences
Phase II Pilot Study of Bevacizumab in Combination with Temozolomide and Regional Radiation Therapy for Up-Front Treatment of Patients With Newly Diagnosed Glioblastoma Multiforme: Interim Analysis of Safety and Tolerability
Albert Lai, Emese Filka, B. McGibbon, Phioanh Leia Nghiemphu, Carrie Graham, William H. Yong, Paul S. Mischel, Linda M. Liau, Marvin Bergsneider, Whitney B. Pope et al. · 2008 · International Journal of Radiation Oncology*Biology*Physics
Resident microglia, and not peripheral macrophages, are the main source of brain tumor mononuclear cells
Annett Müller, Susan Brandenburg, Kati Turkowski, Susanne Müller, Peter Vajkoczy · 2014 · International Journal of Cancer
Autophagy Interplay with Apoptosis and Cell Cycle Regulation in the Growth Inhibiting Effect of Resveratrol in Glioma Cells
Eduardo Cremonese Filippi‐Chiela, Emilly S. Villodre, Lauren Lúcia Zamin, Guido Lenz · 2011 · PLoS ONE
Glioma and glioblastoma - how much do we (not) know?
Ivana Jovčevska, Nina Kočevar Britovšek, Radovan Komel · 2013 · Molecular and Clinical Oncology
Autologous T-cell Therapy for Cytomegalovirus as a Consolidative Treatment for Recurrent Glioblastoma
Andrea Schuessler, Corey Smith, Leone Beagley, Glen M. Boyle, Sweera Rehan, Katherine K. Matthews, Linda Jones, Tania Crough, Vijayendra Dasari, Kerenaftali Klein et al. · 2014 · Cancer Research
The driver and passenger effects of isocitrate dehydrogenase 1 and 2 mutations in oncogenesis and survival prolongation
Remco Jurriaan Molenaar, Tomas Radivoyevitch, Jaroslaw Pawel Maciejewski, Cornelis J.F. Van Noorden, Fonnet E. Bleeker · 2014 · Biochimica et Biophysica Acta (BBA) - Reviews on Cancer
The Risk of Getting Worse: Surgically Acquired Deficits, Perioperative Complications, and Functional Outcomes After Primary Resection of Glioblastoma
Sasha Gulati, Asgeir Store Jakola, Ulf S. Nerland, Clemens Weber, Ole Skeidsvoll Solheim · 2011 · World Neurosurgery
Changes in the EGFR amplification and EGFRvIII expression between paired primary and recurrent glioblastomas
Martin J. van den Bent, Ya Gao, Melissa Kerkhof, Johan M. Kros, Thierry Gorlia, Kitty van Zwieten, Jory Prince, Sjoerd G. van Duinen, Peter A.E. Sillevis Smitt, MARTIN J.B. TAPHOORN et al. · 2015 · Neuro-Oncology
The course of neurocognitive functioning in high-grade glioma patients1
Ingeborg Bosma, Maaike J. Vos, J.J. Heimans, MARTIN J.B. TAPHOORN, Neil K. Aaronson, Tjeerd J. Postma, Henk M. van der Ploeg, Martin Muller, William Peter Vandertop, Ben J. Slotman et al. · 2006 · Neuro-Oncology
Infiltrative and drug‐resistant slow‐cycling cells support metabolic heterogeneity in glioblastoma
Lan Hoang-Minh, Florian A. Siebzehnrübl, Changlin Yang, Silveli Suzuki‐Hatano, Kyle Dajac, Tyler Loche, Nicholas Andrews, Michael Schmoll Massari, Jaimin Patel, Krisha Amin et al. · 2018 · The EMBO Journal
Lnc-TALC promotes O6-methylguanine-DNA methyltransferase expression via regulating the c-Met pathway by competitively binding with miR-20b-3p
Pengfei Wu, Jinquan Cai, Qun Chen, Bo Han, Xiangqi Meng, Yansheng Li, Ziwei Li, Ruijia Wang, Lin Lin, Chunbin Duan et al. · 2019 · Nature Communications
An Electrochemical Biosensor Designed by Using Zr-Based Metal–Organic Frameworks for the Detection of Glioblastoma-Derived Exosomes with Practical Application
Zhaowei Sun, Lei Wang, Shuai Wu, Yanhong Pan, Yu Dong, Sha Zhu, Jie An Yang, Yongmei Yin, Genxi Li · 2020 · Analytical Chemistry
Glioma-derived IL-33 orchestrates an inflammatory brain tumor microenvironment that accelerates glioma progression
Astrid De Boeck, Bo Young Ahn, Charlotte D’Mello, Xueqing Q. Lun, Shyam V. Menon, Mana M. Alshehri, Frank Szulzewsky, Yaoqing Shen, Lubaba Khan, Ngoc Ha Dang et al. · 2020 · Nature Communications
Chlorogenic acid inhibits glioblastoma growth through repolarizating macrophage from M2 to M1 phenotype
Xue, Nina, Zhou, Qin, Ji, Ming, Jin, Jing, Lai, Fangfang, Chen, Ju, Zhang, Mengtian, Jia, Jing, Yang, Huarong, Zhang, Jie et al. · 2017 · Scientific Reports
Biopsy versus partial versus gross total resection in older patients with high-grade glioma: a systematic review and meta-analysis
Saleh A. Almenawer, Jetan H. Badhiwala, Waleed A. Alhazzani, Jeffrey Noah Greenspoon, Forough Farrokhyar, Blake A. Yarascavitch, Almunder R. Algird, Edward Kachur, Aleksa Cenic, Waseem Sharieff et al. · 2015 · Neuro-Oncology
Replication Stress Drives Constitutive Activation of the DNA Damage Response and Radioresistance in Glioblastoma Stem-like Cells
Ross Carruthers, Shafiq Uddin Ahmed, Shaliny Ramachandran, Karen E. Strathdee, Kathreena Mary Kurian, Ann Hedley, Natividad Gomez-Roman, Gabriela Kalna, Mathew Neilson, Lesley Gilmour et al. · 2018 · Cancer Research
Hypoxic Glioma Cell-Secreted Exosomal miR-301a Activates Wnt/β-catenin Signaling and Promotes Radiation Resistance by Targeting TCEAL7
Xiao Yue, Fengming Lan, Tingyi Xia · 2019 · Molecular Therapy
Lessons From Anti–Vascular Endothelial Growth Factor and Anti–Vascular Endothelial Growth Factor Receptor Trials in Patients With Glioblastoma
Lu-Emerson, Christine, Duda, Dan G., Emblem, Kyrre E., Taylor, Jennie W., Gerstner, Elizabeth R., Loeffler, Jay S., Batchelor, Tracy T., Jain, Rakesh K. · 2015 · Journal of Clinical Oncology
Circulating biomarkers for gliomas
Manfred Westphal, Katrin Lamszus · 2015 · Nature Reviews Neurology
TGF-β is an inducer of ZEB1-dependent mesenchymal transdifferentiation in glioblastoma that is associated with tumor invasion
Justin Vareecal Joseph, S Conroy, Tushar Tomar, Ellie Eggens‐Meijer, Krishna Bhat, Sjef C.V.M. Copray, Annemiek Walenkamp, Erik Boddeke, Veerakumar Balasubramaniyan, Michiel Wagemakers et al. · 2014 · Cell Death and Disease
Doxorubicin-loaded nanoparticles consisted of cationic- and mannose-modified-albumins for dual-targeting in brain tumors
Hyeong Jun Byeon, Le Quang Thao, Seung Hyun Lee, Sun Young Min, Eun Seong Lee, Beom Soo Shin, Han‐Gon Choi, Yu Seok Youn · 2016 · Journal of Controlled Release
Glioma through the looking GLASS: molecular evolution of diffuse gliomas and the Glioma Longitudinal Analysis Consortium
Kenneth Aldape, Samirkumar B. Amin, David M. Ashley, Jill S. Barnholtz‐Sloan, Amanda J Bates, Rameen Beroukhim, Christoph Bock, Daniel Jay Brat, Elizabeth B. Claus, J Costello et al. · 2018 · Neuro-Oncology
Magnetic Hyperthermia and Radiation Therapy: Radiobiological Principles and Current Practice †
Spiridon V. Spirou, Martina Basini, A. Lascialfari, Claudio Sangregorio, Claudia Innocenti · 2018 · Nanomaterials
Connexin Hemichannels in Astrocytes: Role in CNS Disorders
Lingyan Xing, Tuo Yang, Shusen Cui, Gang Chen · 2019 · Frontiers in Molecular Neuroscience
Gene Therapy for Drug-Resistant Glioblastoma via Lipid-Polymer Hybrid Nanoparticles Combined with Focused Ultrasound
Qiang Yang, Yanghao Zhou, Jin Chen, Ning Huang, Zhigang Wang, Yuan Zeng Cheng · 2021 · International Journal of Nanomedicine
STING activation promotes robust immune response and NK cell–mediated tumor regression in glioblastoma models
Berger, Gilles, Knelson, Erik H., Jimenez-Macias, Jorge L., Nowicki, Michal O., Han, Saemi, Panagioti, Eleni, Lizotte, Patrick H., Adu-Berchie, Kwasi, Stafford, Alexander, Dimitrakakis, Nikolaos et al. · 2022 · Proceedings of the National Academy of Sciences
A neuropathology-based approach to epilepsy surgery in brain tumors and proposal for a new terminology use for long-term epilepsy-associated brain tumors
Ingmar Blümcke, Eleonora Aronica, Horst Urbach, Andreas V. Alexopoulos, Jorge Alvaro Gonzalez-Martinez · 2014 · Acta Neuropathologica
Umbilical Cord Blood-Derived Mesenchymal Stem Cells Inhibit, But Adipose Tissue-Derived Mesenchymal Stem Cells Promote, Glioblastoma Multiforme Proliferation
Keiko Akimoto, Kenichi Kimura, Masumi Nagano, Shingo Takano, Georgina To’a Salazar, Toshiharu Yamashita, Osamu Ohneda · 2012 · Stem Cells and Development
Experience with irinotecan for the treatment of malignant glioma
James J. Vredenburgh, Annick Desjardins, David A. Reardon, Henry S. Friedman · 2008 · Neuro-Oncology
The miR 302-367 cluster drastically affects self-renewal and infiltration properties of glioma-initiating cells through CXCR4 repression and consequent disruption of the SHH-GLI-NANOG network
Mohamed Fareh, Laurent Turchi, Virginie Virolle, D Debruyne, Fabien Almairac, Stéphanie Beghelli-de la Forest Divonne, Philippe Paquis, Olivier Preynat‐Seauve, K-H Krause, Hervé Chneiweiss et al. · 2011 · Cell Death and Differentiation
Randomized Phase II Trial of Chemoradiotherapy Followed by Either Dose-Dense or Metronomic Temozolomide for Newly Diagnosed Glioblastoma
Jennifer Leigh Clarke, FABIO MASSAITI IWAMOTO, Joohee Sul, Katherine S. Panageas, Andrew B. Lassman, Lisa Marie DeAngelis, Adı́lia Hormigo, Craig P. Nolan, Igor T. Gavrilovic, Sasan Karimi et al. · 2009 · Journal of Clinical Oncology
A Distinct DNA Methylation Shift in a Subset of Glioma CpG Island Methylator Phenotypes during Tumor Recurrence
Camila Ferreira de Souza, Thaís S. Sabedot, Tathiane Maistro Malta, Lindsay C. Stetson, Olena Morozova, Artem Sokolov, Peter W. Laird, Maciej Wiznerowicz, Antonio Iavarone, James Snyder et al. · 2018 · Cell Reports
Temozolomide: An Updated Overview of Resistance Mechanisms, Nanotechnology Advances and Clinical Applications
Raúl Ortíz, Gloria Perazzoli, Laura Cabeza, Cristina Jiménez‐Luna, Raquel Luque, Jose Carlos Prados, Consolación Melguizo · 2020 · Current Neuropharmacology
Tumor treating fields: A novel treatment modality and its use in brain tumors
Hottinger, Andreas F., Pacheco, Patricia, Stupp, Roger · 2016 · Neuro-Oncology
Glioblastoma therapy in the elderly and the importance of the extent of resection regardless of age
Ági Oszvald, Erdem Güresir, Matthias Setzer, Hartmut Vatter, Christian Senft, Volker Seifert, Kea Franz · 2011 · Journal of neurosurgery
Drug repurposing: sulfasalazine sensitizes gliomas to gamma knife radiosurgery by blocking cystine uptake through system Xc−, leading to glutathione depletion
Linda Sleire, Bente Sandvei Skeie, Inger Anne Netland, Hilde Elise Førde, Ernest Dodoo, Frode Selheim, Lina Wik Leiss, Jan Heggdal, Pedersen Ph, Jian Wang et al. · 2015 · Oncogene
Potential Value of miR-221/222 as Diagnostic, Prognostic, and Therapeutic Biomarkers for Diseases
Jialin Song, Yuanming Ouyang, Junyi Che, Xiaoming Li, Yi Zhao, Kejia Yang, Xiaotian Zhao, Yinghui Chen, Cunyi Fan, Weien Yuan · 2017 · Frontiers in Immunology
The Endogenous Tryptophan Metabolite and NAD+ Precursor Quinolinic Acid Confers Resistance of Gliomas to Oxidative Stress
Felix Sahm, Iris Oezen, Christiane A. Opitz, Bernhard Radlwimmer, Andreas von Deimling, Tilman Ahrendt, Seray Adams, Helge B. Bode, Gilles J. Guillemin, Wolfgang Wick et al. · 2013 · Cancer Research
Glycoprotein Nonmetastatic Melanoma Protein B, a Potential Molecular Therapeutic Target in Patients with Glioblastoma Multiforme
Chien-Tsun Kuan, Kenji Wakiya, Jeannette M. Dowell, James E. Herndon, David A. Reardon, Michael W. Graner, Gregory Joseph Riggins, Carol J. Wikstrand, Darell D. Bigner · 2006 · Clinical Cancer Research
A pilot study of everolimus and gefitinib in the treatment of recurrent glioblastoma (GBM)
Teri Nguyen Kreisl, Andrew B. Lassman, Paul S. Mischel, Neal X. Rosen, Howard I. Scher, Julie Teruya‐Feldstein, David R. Shaffer, Eric Lis, Lauren E. Abrey · 2008 · Journal of Neuro-Oncology
How tissue fluidity influences brain tumor progression
Kaspar‐Josche Streitberger, Ledia Lilaj, Felix Schrank, Jürgen Braun, Karl‐Titus Hoffmann, M Reiss-Zimmermann, Josef Alfons Käs, Ingolf Sack · 2019 · Proceedings of the National Academy of Sciences
Photodynamic Therapy for the Treatment of Glioblastoma
Samuel W. Cramer, Clark C. Chen · 2020 · Frontiers in Surgery
DNA binding, nucleotide flipping, and the helix-turn-helix motif in base repair by O6-alkylguanine-DNA alkyltransferase and its implications for cancer chemotherapy
Julie L. Tubbs, Anthony E. Pegg, John A. Tainer · 2007 · DNA repair
Dicer-regulated microRNAs 222 and 339 promote resistance of cancer cells to cytotoxic T-lymphocytes by down-regulation of ICAM-1
Ryo Ueda, Gary Kohanbash, Kotaro Sasaki, Mitsugu Fujita, Xinmei Zhu, Edward R. Kastenhuber, Heather A. McDonald, Douglas M. Potter, Ronald L. Hamilton, Michael T. Lotze et al. · 2009 · Proceedings of the National Academy of Sciences
Cancer stem cells: Cell culture, markers, and targets for new therapies
Candace A. Gilbert, Alonzo H. Ross · 2009 · Journal of Cellular Biochemistry
Perifosine Inhibits Multiple Signaling Pathways in Glial Progenitors and Cooperates With Temozolomide to Arrest Cell Proliferation in Gliomas In vivo
Hiroyuki Momota, Edward Nerio, Eric C. Holland · 2005 · Cancer Research
Microglia and Macrophages in Malignant Gliomas: Recent Discoveries and Implications for Promising Therapies
Anna Carolina Carvalho da Fonseca, Behnam Badie · 2013 · Clinical and Developmental Immunology
International retrospective study of over 1000 adults with anaplastic oligodendroglial tumors
Andrew B. Lassman, FABIO MASSAITI IWAMOTO, Timothy Francis Cloughesy, Kenneth Aldape, Andreana Laura Rivera, April F. Eichler, David N. Louis, Nina A. Paleologos, B. J. Fisher, Landon Ashby et al. · 2011 · Neuro-Oncology
The Next Generation of Glioma Biomarkers: MGMT Methylation, BRAF Fusions and IDH1 Mutations
Andreas von Deimling, Andrey Korshunov, Christian Johannes Hartmann · 2010 · Brain Pathology
Correlation of hypoxic cell fraction and angiogenesis with glucose metabolic rate in gliomas using 18F-fluoromisonidazole, 18F-FDG PET, and immunohistochemical studies.
Lawrence Cher, Carmel Murone, Nathan Lawrentschuk, S. Ramdave, Anthony T. Papenfuss, Anthony Hannah, Graeme Joseph O'Keefe, John I. Sachinidis, Salvatore U. Berlangieri, Gavin Fabinyi et al. · 2006 · PubMed
Dual IRE1 RNase functions dictate glioblastoma development
Stéphanie Lhomond, Tony Avril, Nicolas Dejeans, Konstantinos Voutetakis, Dimitrios Doultsinos, Mari McMahon, Raphaël Pineau, Joanna Obacz, Olga Papadodima, Florence Jouan et al. · 2018 · EMBO Molecular Medicine
Glioblastoma Therapy Using Codelivery of Cisplatin and Glutathione Peroxidase Targeting siRNA from Iron Oxide Nanoparticles
Yulin Zhang, Xiao Fu, Junsheng Jia, Tobias Wikerholmen, Kaiyan Xi, Yang Kong, Junpeng Wang, Haijun Chen, Yuan Ma, Zhiwei Li et al. · 2020 · ACS Applied Materials & Interfaces
Glioblastoma in adults
Alba Ariela Brandes, Alicia Tosoni, Enrico Franceschi, Michele Reni, Gemma Gatta, Charles J. Vecht · 2008 · Critical Reviews in Oncology/Hematology
Constitutive Activation of Signal Transducer and Activator of Transcription 3 (STAT3) and Nuclear Factor κB Signaling in Glioblastoma Cancer Stem Cells Regulates the Notch Pathway
Jo Meagan Garner, Meiyun Fan, Chuan He Yang, Ziyun Du, Michelle M. Sims, Andrew M. Davidoff, Lawrence M. Pfeffer · 2013 · Journal of Biological Chemistry
Challenges in the Treatment of Glioblastoma: Multisystem Mechanisms of Therapeutic Resistance
Evan Noch, Rohan R. Ramakrishna, Rajiv Magge · 2018 · World Neurosurgery
Current Immunotherapies for Glioblastoma Multiforme
Boyuan Huang, Xuesong Li, Yuntao Li, Jin Zhang, Zhitao Zong, Hongbo Zhang · 2021 · Frontiers in Immunology
Depatuxizumab mafodotin in EGFR-amplified newly diagnosed glioblastoma: A phase III randomized clinical trial
Andrew B. Lassman, Stephanie L. Pugh, Tony J. C. Wang, Kenneth Aldape, Hui Kong Gan, Matthias Preusser, Michael A. Vogelbaum, Erik P. Sulman, Minhee Won, Peixin Zhang et al. · 2022 · Neuro-Oncology
Immune evasion mediated by tumor-derived lactate dehydrogenase induction of NKG2D ligands on myeloid cells in glioblastoma patients
Courtney A. Crane, Kathryn Austgen, Kristen Haberthur, Carly C. Hofmann, K. Moyes, L. Avanesyan, L. Fong, M. Campbell, Stewart L. Cooper, Scott A. Oakes et al. · 2014 · Proceedings of the National Academy of Sciences of the United States of America
Changes in Relative Cerebral Blood Volume 1 Month after Radiation-Temozolomide Therapy Can Help Predict Overall Survival in Patients with Glioblastoma
Rajiv Mangla, Gurshawn Singh, Doerthe Ziegelitz, Michael T. Milano, David Nathan Korones, Jianhui Zhong, SVEN E. EKHOLM · 2010 · Radiology
Detection of Brain Tumor Cells in the Peripheral Blood by a Telomerase Promoter-Based Assay
Kelly M. MacArthur, Gary D. Kao, Sanjay Chandrasekaran, Michelle Alonso‐Basanta, Christina Hunter Chapman, Robert A. Lustig, E. Paul Wileyto, Stephen M. Hahn, Jay F. Dorsey · 2014 · Cancer Research
O6-Methylguanine-DNA Methyltransferase Expression Strongly Correlates With Outcome in Childhood Malignant Gliomas: Results From the CCG-945 Cohort
Ian F. Pollack, Ronald L. Hamilton, Robert William Sobol, Judith A. Burnham, Allan James Yates, Emiko J. Holmes, Tianni Zhou, Jonathan L. Finlay · 2006 · Journal of Clinical Oncology
A phase II study evaluating the efficacy and safety of AMG 102 (rilotumumab) in patients with recurrent glioblastoma
Patrick Yung Wen, David Schiff, Timothy Francis Cloughesy, Jeffrey J. Raizer, John Laterra, Melanie C. Smitt, M. Wolf, Kelly Smith Oliner, Abraham Anderson, Min Zhu et al. · 2011 · Neuro-Oncology
Applying amide proton transfer‐weighted MRI to distinguish pseudoprogression from true progression in malignant gliomas
Bo Ma, Jaishri O'Neill Blakeley, Xiaohua Hong, Hongyan Zhang, Shanshan Jiang, Lindsay Blair, Yi Zhang, Hye‐Young Heo, Mingzhi Zhang, Peter C.M. van Zijl et al. · 2016 · Journal of Magnetic Resonance Imaging
A Cancer Research UK First Time in Human Phase I Trial of IMA950 (Novel Multipeptide Therapeutic Vaccine) in Patients with Newly Diagnosed Glioblastoma
R. Rampling, Sharon Peoples, Paul James Mulholland, Allan James, Omar Al‐Salihi, Christopher Twelves, Catherine A. McBain, Sarah Jefferies, Alan Jackson, William B. Stewart Jr. et al. · 2016 · Clinical Cancer Research
Splicing factor SRSF1 promotes gliomagenesis via oncogenic splice-switching of MYO1B
Xuexia Zhou, Run Wang, Xuebing Li, Lin Yu, Dan Hua, Cuiyun Sun, Cuijuan Shi, Wenjun Luo, Chun Rao, Zhendong Jiang et al. · 2018 · Journal of Clinical Investigation