Weller, Michael

Radiotherapy Plus Concomitant and Adjuvant Temozolomide for Glioblastoma

Stupp, R., Mason, W. P., van den Bent, M. J., Weller, M., Fisher, B., Taphoorn, M. J. B., Belanger, K., Brandes, A. A., Marosi, C., Bogdahn, U., et al. (2005) · New England Journal of Medicine

Glioma Diagnosis and TreatmentPARP inhibition in cancer therapy

Cited by 21,807

MGMT Gene Silencing and Benefit from Temozolomide in Glioblastoma

Hegi, M. E., Diserens, A.-C., Gorlia, T., Hamou, M.-F., de Tribolet, N., Weller, M., Kros, J. M., Hainfellner, J. A., Mason, W., Mariani, L., et al. (2005) · New England Journal of Medicine

Glioma Diagnosis and TreatmentPARP inhibition in cancer therapy

Cited by 7,405

Effect of Tumor-Treating Fields Plus Maintenance Temozolomide vs Maintenance Temozolomide Alone on Survival in Patients With Glioblastoma: A Randomized Clinical Trial

Stupp, R., Taillibert, S., Kanner, A., Read, W., Steinberg, D. M., Lhermitte, B., Toms, S., Idbaih, A., Ahluwalia, M. S., Fink, K., et al. (2017) · JAMA

Glioma Diagnosis and TreatmentElectromagnetic Fields and Biological Effects

Cited by 2,644

EANO guidelines on the diagnosis and treatment of diffuse gliomas of adulthood

Weller, M., van den Bent, M., Preusser, M., Le Rhun, E., Tonn, J. C., Minniti, G., Bendszus, M., Balana, C., Chinot, O., Dirven, L., et al. (2021) · Nature Reviews Clinical Oncology

Glioma Diagnosis and TreatmentAdvanced Neuroimaging Techniques and Applications

Cited by 2,048

An endogenous tumour-promoting ligand of the human aryl hydrocarbon receptor

Opitz, C. A., Litzenburger, U. M., Sahm, F., Ott, M., Tritschler, I., Trump, S., Schumacher, T., Jestaedt, L., Schrenk, D., Weller, M., et al. (2011) · Nature

Tryptophan and brain disordersToxic Organic Pollutants Impact

Cited by 1,898

Glioblastoma in adults: a Society for Neuro-Oncology (SNO) and European Society of Neuro-Oncology (EANO) consensus review on current management and future directions

Wen, P. Y., Weller, M., Lee, E. Q., Alexander, B. M., Barnholtz-Sloan, J. S., Barthel, F. P., Batchelor, T. T., Bindra, R. S., Chang, S. M., Chiocca, E. A., et al. (2020) · Neuro-Oncology

Glioma Diagnosis and TreatmentOvarian cancer diagnosis and treatment

Cited by 1,168

Cilengitide combined with standard treatment for patients with newly diagnosed glioblastoma with methylated MGMT promoter (CENTRIC EORTC 26071-22072 study): a multicentre, randomised, open-label, phase 3 trial

Stupp, R., Hegi, M. E., Gorlia, T., Erridge, S. C., Perry, J., Hong, Y.-K., Aldape, K. D., Lhermitte, B., Pietsch, T., Grujicic, D., et al. (2014) · The Lancet Oncology

Glioma Diagnosis and TreatmentPARP inhibition in cancer therapy

Cited by 1,052

Advances in the molecular genetics of gliomas — implications for classification and therapy

Reifenberger, G., Wirsching, H.-G., Knobbe-Thomsen, C. B., & Weller, M. (2017) · Nature Reviews Clinical Oncology

Glioma Diagnosis and TreatmentCancer Genomics and Diagnostics

Cited by 662

EANO-ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up of patients with leptomeningeal metastasis from solid tumours

Le Rhun, E., Weller, M., Brandsma, D., Van den Bent, M., de Azambuja, E., Henriksson, R., Boulanger, T., Peters, S., Watts, C., Wick, W., et al. (2017) · Annals of Oncology

Brain Metastases and TreatmentManagement of metastatic bone disease

Cited by 637

Federated learning enables big data for rare cancer boundary detection

Pati, S., Baid, U., Edwards, B., Sheller, M., Wang, S.-H., Reina, G. A., Foley, P., Gruzdev, A., Karkada, D., Davatzikos, C., et al. (2022) · Nature Communications

Privacy-Preserving Technologies in DataBrain Tumor Detection and Classification

Cited by 394

Acid sphingomyelinase–ceramide system mediates effects of antidepressant drugs

Gulbins, E., Palmada, M., Reichel, M., Lüth, A., Böhmer, C., Amato, D., Müller, C. P., Tischbirek, C. H., Groemer, T. W., Tabatabai, G., et al. (2013) · Nature Medicine

Sphingolipid Metabolism and SignalingTreatment of Major Depression

Cited by 384

ATRX loss refines the classification of anaplastic gliomas and identifies a subgroup of IDH mutant astrocytic tumors with better prognosis

Wiestler, B., Capper, D., Holland-Letz, T., Korshunov, A., von Deimling, A., Pfister, S. M., Platten, M., Weller, M., & Wick, W. (2013) · Acta Neuropathologica

Glioma Diagnosis and TreatmentAcute Myeloid Leukemia Research

Cited by 346

HLA Ligand Atlas: a benign reference of HLA-presented peptides to improve T-cell-based cancer immunotherapy

Marcu, A., Bichmann, L., Kuchenbecker, L., Kowalewski, D. J., Freudenmann, L. K., Backert, L., Mühlenbruch, L., Szolek, A., Lübke, M., Wagner, P., et al. (2021) · Journal for ImmunoTherapy of Cancer

vaccines and immunoinformatics approachesImmunotherapy and Immune Responses

Cited by 250

Liquid biopsy in central nervous system metastases: a RANO review and proposals for clinical applications

Boire, A., Brandsma, D., Brastianos, P. K., Le Rhun, E., Ahluwalia, M., Junck, L., Glantz, M., Groves, M. D., Lee, E. Q., Lin, N., et al. (2019) · Neuro-Oncology

Brain Metastases and TreatmentCancer Genomics and Diagnostics

Cited by 183

Depolarization or glutamate receptor activation blocks apoptotic cell death of cultured cerebellar granule neurons

Yan, G.-M., Ni, B., Weller, M., Wood, K. A., & Paul, S. M. (1994) · Brain Research

Cell death mechanisms and regulationNeuroscience and Neuropharmacology Research

Cited by 171

Microbial peptides activate tumour-infiltrating lymphocytes in glioblastoma

Naghavian, R., Faigle, W., Oldrati, P., Wang, J., Toussaint, N. C., Qiu, Y., Medici, G., Wacker, M., Freudenmann, L. K., Bonté, P.-E., et al. (2023) · Nature

Immunotherapy and Immune ResponsesCancer Immunotherapy and Biomarkers

Cited by 163

CP-31398, a novel p53-stabilizing agent, induces p53-dependent and p53-independent glioma cell death

Wischhusen, J., Naumann, U., Ohgaki, H., Rastinejad, F., & Weller, M. (2003) · Oncogene

Cancer-related Molecular PathwaysCell death mechanisms and regulation

Cited by 158

Immunocytokines are a promising immunotherapeutic approach against glioblastoma

Weiss, T., Puca, E., Silginer, M., Hemmerle, T., Pazahr, S., Bink, A., Weller, M., Neri, D., & Roth, P. (2020) · Science Translational Medicine

Glioma Diagnosis and TreatmentCancer Immunotherapy and Biomarkers

Cited by 133

Molecular determinants of glioma cell migration and invasion

Wild-Bode, C., Weller, M., & Wick, W. (2001) · Journal of Neurosurgery

Protease and Inhibitor MechanismsGlioma Diagnosis and Treatment

Cited by 130

How we treat patients with leptomeningeal metastases

Le Rhun, E., Preusser, M., van den Bent, M., Andratschke, N., & Weller, M. (2019) · ESMO Open

Brain Metastases and TreatmentManagement of metastatic bone disease

Cited by 127

Multidimensional scaling of diffuse gliomas: Application to the 2016 World Health Organization classification system with prognostically relevant molecular subtype discovery

Cimino, P. J., Zager, M., McFerrin, L., Wirsching, H.-G., Bolouri, H., Hentschel, B., von Deimling, A., Jones, D., Reifenberger, G., Weller, M., et al. (2017) · Acta Neuropathologica Communications

Glioma Diagnosis and TreatmentCancer Genomics and Diagnostics

Cited by 126

CODEL: Phase III study of RT, RT + TMZ, or TMZ for newly diagnosed 1p/19q codeleted oligodendroglioma. Analysis from the initial study design

Jaeckle, K. A., Ballman, K. V., van den Bent, M., Giannini, C., Galanis, E., Brown, P. D., Jenkins, R. B., Cairncross, J. G., Wick, W., Weller, M., et al. (2021) · Neuro-Oncology

Glioma Diagnosis and TreatmentPARP inhibition in cancer therapy

Cited by 119

Biological activity of tumor-treating fields in preclinical glioma models

Silginer, M., Weller, M., Stupp, R., & Roth, P. (2017) · Cell Death & Disease

Glioma Diagnosis and TreatmentElectromagnetic Fields and Biological Effects

Cited by 111

Glioblastoma epigenome profiling identifies SOX10 as a master regulator of molecular tumour subtype

Wu, Y., Fletcher, M., Gu, Z., Wang, Q., Costa, B., Bertoni, A., Man, K.-H., Schlotter, M., Felsberg, J., Mangei, J., et al. (2020) · Nature Communications

Glioma Diagnosis and TreatmentEpigenetics and DNA Methylation

Cited by 101