The DOI matches its Crossref record; 42 of the 42 references it cites were found in a registry or an index.
Homocysteine Lowering and Cardiovascular Events after Acute Myocardial Infarction
Open accessAbstract
BACKGROUND: Homocysteine is a risk factor for cardiovascular disease. We evaluated the efficacy of homocysteine-lowering treatment with B vitamins for secondary prevention in patients who had had an acute myocardial infarction. METHODS: The trial included 3749 men and women who had had an acute myocardial infarction within seven days before randomization. Patients were randomly assigned, in a two-by-two factorial design, to receive one of the following four daily treatments: 0.8 mg of folic acid, 0.4 mg of vitamin B12, and 40 mg of vitamin B6; 0.8 mg of folic acid and 0.4 mg of vitamin B12; 40 mg of vitamin B6; or placebo. The primary end point during a median follow-up of 40 months was a composite of recurrent myocardial infarction, stroke, and sudden death attributed to coronary artery disease. RESULTS: The mean total homocysteine level was lowered by 27 percent among patients given folic acid plus vitamin B12, but such treatment had no significant effect on the primary end point (risk ratio, 1.08; 95 percent confidence interval, 0.93 to 1.25; P=0.31). Also, treatment with vitamin B6 was not associated with any significant benefit with regard to the primary end point (relative risk of the primary end point, 1.14; 95 percent confidence interval, 0.98 to 1.32; P=0.09). In the group given folic acid, vitamin B12, and vitamin B6, there was a trend toward an increased risk (relative risk, 1.22; 95 percent confidence interval, 1.00 to 1.50; P=0.05). CONCLUSIONS: Treatment with B vitamins did not lower the risk of recurrent cardiovascular disease after acute myocardial infarction. A harmful effect from combined B vitamin treatment was suggested. Such treatment should therefore not be recommended. (ClinicalTrials.gov number, NCT00266487.).
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Davey Smith, G., & Ebrahim, S. (2003) · International Journal of Epidemiology · doi:10.1093/ije/dyg070 · Cited by 5,882
Homocysteine and Risk of Ischemic Heart Disease and Stroke: A Meta-analysis
Homocysteine Studies Collaboration (2002) · JAMA · doi:10.1001/jama.288.16.2015 · Cited by 2,059
Homocysteine and cardiovascular disease: evidence on causality from a meta-analysis
Wald, D. S., Law, M., & Morris, J. K. (2002) · BMJ · doi:10.1136/bmj.325.7374.1202 · Cited by 1,945
Plasma Homocysteine Levels and Mortality in Patients with Coronary Artery Disease
Nygard, O. K., Nordrehaug, J. E., Refsum, H., Ueland, P. M., Farstad, M., & Vollset, S. E. (1997) · New England Journal of Medicine · doi:10.1056/nejm199707243370403 · Cited by 1,746
Self-citationHomocysteine Lowering with Folic Acid and B Vitamins in Vascular Disease
(2006) · New England Journal of Medicine · doi:10.1056/nejmoa060900 · Cited by 1,729
A strategy to reduce cardiovascular disease by more than 80%
Wald, N., & Law, M. R. (2003) · BMJ · doi:10.1136/bmj.326.7404.1419 · Cited by 1,565
Toole, J. F., Malinow, M. R., Chambless, L. E., Spence, J. D., Pettigrew, L. C., Howard, V. J., Sides, E. G., Wang, C.-H., & Stampfer, M. (2004) · JAMA · doi:10.1001/jama.291.5.565 · Cited by 1,391
The Effect of Folic Acid Fortification on Plasma Folate and Total Homocysteine Concentrations
Jacques, P. F., Selhub, J., Bostom, A. G., Wilson, P. W. F., & Rosenberg, I. H. (1999) · New England Journal of Medicine · doi:10.1056/nejm199905133401901 · Cited by 1,117
Serum Total Homocysteine and Coronary Heart Disease
Arnesen, E., Refsum, H., Bønaa, K. H., Ueland, P. M., Førde, O. H., & Nordrehaug, J. E. (1995) · International Journal of Epidemiology · doi:10.1093/ije/24.4.704 · Cited by 650
Self-citationFolsom, A. R., Nieto, F. J., McGovern, P. G., Tsai, M. Y., Malinow, M. R., Eckfeldt, J. H., Hess, D. L., & DAVIS, C. E. (1998) · Circulation · doi:10.1161/01.cir.98.3.204 · Cited by 603
Flagged first, then by citations
Research works printed but not linked: 2
- Baker F, 2002, Circulation, 106, II
- Matsubara K, 2004, Int J Mol Med, 14, 819
Cited by
Sorted by citations
Items 801–900 of 1,000
Coria-Ramírez, É., Nieto‐Cisneros, L., Treviño‐Pérez, S., Ibarra‐González, I., Casillas-Rodríguez, J., & Majluf‐Cruz, A. (2010) · JAIDS Journal of Acquired Immune Deficiency Syndromes · doi:10.1097/qai.0b013e3181d91088 · Cited by 12
Nevado, J. B., & Imasa, M. S. B. (2008) · Coronary Artery Disease · doi:10.1097/mca.0b013e3282f52910 · Cited by 12
Cautionary tales in the interpretation of observational studies of effects of clinical interventions
Scott, I. A., & Attia, J. (2016) · Internal Medicine Journal · doi:10.1111/imj.13167 · Cited by 12
Medical Treatment of Peripheral Artery Disease
Gornik, H. L., & Creager, M. A. (2013) · Vascular Medicine: A Companion to Braunwald's Heart Disease · doi:10.1016/b978-1-4377-2930-6.00019-7 · Cited by 12
Wei, J., & Ji, J. S. (2020) · BMJ Nutrition Prevention & Health · doi:10.1136/bmjnph-2020-000088 · Cited by 12
Folate Status and Mortality in US Adults With Diabetes: A Nationally Representative Cohort Study
Xiong, H., Li, X., Cheng, S., Chen, P., Guo, S., Huang, X., & Lu, Y. (2022) · Frontiers in Cardiovascular Medicine · doi:10.3389/fcvm.2022.802247 · Cited by 12
Marosi, K., Ágota, A., Végh, V., Joó, J. G., Langmár, Z., Kriszbacher, I., & Nagy, Z. B. (2012) · Orvosi Hetilap · doi:10.1556/oh.2012.29326 · Cited by 12
Long-term prognostic significance of homocysteine in middle-aged and elderly
Petersen, J. F., Larsen, B. S., Sabbah, M., Nielsen, O. W., Kumarathurai, P., & Sajadieh, A. (2016) · Biomarkers · doi:10.3109/1354750x.2016.1160288 · Cited by 12
Nursalim, A., Siregar, P., & Widyahening, I. S. (2013) · PubMed · Cited by 12
Correlation between serum homocysteine concentration and severity of mitral valve disease in dogs
Lee, C., Jeong, D.-M., Kang, M., Kim, S.-G., Han, J., & Park, H. (2017) · American Journal of Veterinary Research · doi:10.2460/ajvr.78.4.440 · Cited by 12
Potential Anti-Inflammatory Treatment of Ischaemic Hearth Disease
Hodžić, E. (2018) · Medical Archives · doi:10.5455/medarh.2018.72.94-98 · Cited by 12
Dhar, I., Lysne, V., Svingen, G. F. T., Ueland, P. M., Gregory, J. F., Bønaa, K. H., & Nygard, O. K. (2019) · American Journal of Clinical Nutrition · doi:10.1093/ajcn/nqy391 · Cited by 12
Self-citationHOPE 2: can supplementation with folic acid and B vitamins reduce cardiovascular risk?
Kullo, I. J. (2006) · Nature Clinical Practice Cardiovascular Medicine · doi:10.1038/ncpcardio0611 · Cited by 12
Oxidant stress in HIV-infected women from the Women's Interagency HIV Study
Glesby, M. J., Hoover, D. R., Raiszadeh, F., Lee, I., Shi, Q., Milne, G. L., Sanchez, S. C., Gao, W., Kaplan, R. C., Morrow, J. D., et al. (2008) · Antiviral Therapy · doi:10.3851/imp1290 · Cited by 12
Perspective on the efficacy analysis of the Vitamin Intervention for Stroke Prevention trial
Spence, J. D. (2007) · Clinical Chemistry and Laboratory Medicine (CCLM) · doi:10.1515/cclm.2007.325 · Cited by 12
Glucosinolate and folate content in sprouted broccoli seeds
Rychlik, M., & Adam, S. T. (2007) · European Food Research and Technology · doi:10.1007/s00217-007-0631-y · Cited by 12
Interventions for lowering plasma homocysteine levels in kidney transplant recipients
Kang, A., Nigwekar, S. U., Perkovic, V., Kulshrestha, S., Zoungas, S., Navaneethan, S. D., Cass, A., Gallagher, M., Ninomiya, T., Strippoli, G. F., et al. (2015) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd007910.pub2 · Cited by 12
Preston, S. L., & Jankowski, J. A. (2006) · Gut · doi:10.1136/gut.2006.096461 · Cited by 12
Epidemiology of Coronary Heart Disease in the Elderly
Vokonas, P., & Kannel, W. B. (2008) · Fundamental and clinical cardiology · doi:10.3109/9781420061710.008 · Cited by 12
Link between Homocysteine and Cardiovascular Diseases
Obradovic, M. M., Zarić, B. L., Haidara, M. A., & Isenović, E. R. (2017) · Current Pharmacology Reports · doi:10.1007/s40495-017-0119-9 · Cited by 12
Preventing Recurrent Stroke and Other Serious Vascular Events
Warlow, C. P., van Gijn, J., Dennis, M. S., Wardlaw, J. M., Bamford, J., Hankey, G. J., Sandercock, P. A., Rinkel, G. J. E., Langhorne, P., Sudlow, C. L. M., et al. (2008) · Stroke · doi:10.1002/9780470696361.ch16 · Cited by 12
Prospects for a Cardiovascular Disease Prevention Polypill
Dabhadkar, K. C., Kulshreshtha, A., Ali, M. K., & Narayan, K. M. V. (2011) · Annual Review of Public Health · doi:10.1146/annurev-publhealth-031210-101214 · Cited by 11
Use and role of monoclonal antibodies and other biologics in preventive cardiology
Gencer, B., Laaksonen, R., Buhayer, A., & Mach, F. (2015) · Swiss Medical Weekly · doi:10.4414/smw.2015.14179 · Cited by 11
Vučković, B., Čabarkapa, V., Ilić, T., Salatić, I., Lozanov-Crvenković, Z., & Mitic, G. P. (2013) · Croatian Medical Journal · doi:10.3325/cmj.2013.54.480 · Cited by 11
Braun, L. T. (2006) · The Journal of Cardiovascular Nursing · doi:10.1097/00005082-200611001-00004 · Cited by 11
Chen, Y., Cao, Y., Zhou, J., & Liu, X. (2009) · Pharmaceutical Research · doi:10.1007/s11095-009-9899-x · Cited by 11
Methods for assessment of folate (Vitamin B9)
Sobczyńska‐Malefora, A. (2018) · Elsevier eBooks · doi:10.1016/b978-0-12-813050-6.00011-5 · Cited by 11
Patel, P. D., & Arora, R. R. (2010) · American Journal of Therapeutics · doi:10.1097/mjt.0b013e3181727d06 · Cited by 11
WENGER, N. K. (2011) · Clinical Cardiology · doi:10.1002/clc.20940 · Cited by 11
Primary Prevention and Health Services Delivery
Goldstein, L. B., & Rothwell, P. M. (2007) · Stroke · doi:10.1161/01.str.0000254717.89942.67 · Cited by 11
Ni, M., Zhang, X. H., Jiang, S. L., & Zhang, Y. (2007) · The American Journal of Cardiology · doi:10.1016/j.amjcard.2007.03.046 · Cited by 11
Cardiorespiratory fitness and plasma homocysteine levels in adult males and females.
Dankner, R. S., Geulayov, G., Farber, N., Novikov, I., Segev, S., & Sela, B. (2009) · PubMed · Cited by 11
Serum homocysteine is associated with the severity of primary chronic venous disease
Smith, R. K., Quigley, F., Tosenovsky, P., Velu, R., Bradshaw, B., Buettner, P. G., & Golledge, J. (2015) · Phlebology The Journal of Venous Disease · doi:10.1177/0268355515592076 · Cited by 11
Homocysteine Lowering with Folic Acid and B Vitamins in Vascular Disease
Rabinstein, A. A. (2007) · Yearbook of Neurology and Neurosurgery · doi:10.1016/s0513-5117(08)70006-1 · Cited by 11
Papazafiropoulou, A. K., Tentolouris, N., Moyssakis, I. E., Perrea, D. N., & Katsilambros, N. L. (2006) · Diabetes Care · doi:10.2337/dc06-0154 · Cited by 11
Homocysteine Lowering with Folic Acid and B Vitamins in Vascular Disease
Frishman, W. H. (2007) · Yearbook of Medicine · doi:10.1016/s0084-3873(08)70204-9 · Cited by 11
Szolnoki, Z., Maász, A., Magyari, L., Horvatovich, K., Faragó, B., Somogyvári, F., Kondacs, A., Szabó, M., Bodor, A., Hadarits, F., et al. (2007) · Journal of Molecular Neuroscience · doi:10.1385/jmn:31:03:201 · Cited by 11
Plasma Homocysteine Is Not Associated With HIV Serostatus or Antiretroviral Therapy in Women
Raiszadeh, F., Hoover, D. R., Lee, I. J.-A., Shi, Q., Anastos, K., Gao, W., Kaplan, R. C., & Glesby, M. J. (2009) · JAIDS Journal of Acquired Immune Deficiency Syndromes · doi:10.1097/qai.0b013e3181a42bdf · Cited by 10
From A to E: Uniting vitamins against stroke risk—A systematic review and network meta‐analysis
Tripathi, S., Nath, M., Misra, S., & Kumar, P. (2024) · European Journal of Clinical Investigation · doi:10.1111/eci.14165 · Cited by 10
Homocysteine concentration in coronary artery disease and severity of coronary lesions
Luo, Z., Tang, K., Huang, G., Wang, X., Zhou, S., Dai, D., Yang, H., & Jiang, W. (2024) · Journal of Cellular and Molecular Medicine · doi:10.1111/jcmm.18474 · Cited by 10
Algae and cardiovascular health
Sánchez-Muniz, F. J., de Juana, A. B., Bastida, S., & Benedı́, J. (2013) · Elsevier eBooks · doi:10.1533/9780857098689.2.369 · Cited by 10
Salvo, G. D., Bello, V. D., Salustri, A., Antonini‐Canterin, F., Carrubba, S. L., Materazzo, C., Badano, L. P., Caso, P., Pezzano, A., Calabrò, R., et al. (2011) · Clinical Cardiology · doi:10.1002/clc.20933 · Cited by 10
Papoutsakis, C., Μanios, Y., Magkos, F., Papaconstantinou, E., Schulpis, K. H., Zampelas, A., Matalas, A., & Yiannakouris, N. (2010) · Nutrition · doi:10.1016/j.nut.2009.09.022 · Cited by 10
Wang, M. T. M., Gamble, G. D., Bolland, M. J., & Grey, A. B. (2014) · PLoS ONE · doi:10.1371/journal.pone.0101533 · Cited by 10
Risk Markers for Atherothrombotic Disease
Ridker, P. M., & Libby, P. (2012) · Elsevier eBooks · doi:10.1016/b978-1-4377-0398-6.00044-5 · Cited by 10
Horváth, B., Szapáry, L., Debreceni, L., Fehér, G., Kenyeres, P., Fulop, A., Battyáni, I., & Tóth, K. (2009) · Clinical Hemorheology and Microcirculation · doi:10.3233/ch-2009-1182 · Cited by 10
Screening for coagulation disorders in patients with ischemic stroke
de Lau, L. M. L., Leebeek, F. W. G., de Maat, M. P. M., Koudstaal, P. J., & Dippel, D. W. J. (2010) · Expert Review of Neurotherapeutics · doi:10.1586/ern.10.104 · Cited by 10
[Risk factors for cardiovascular diseases: what is the role for homocysteine?].
Bendini, M. G., Lanza, G. A., Mazza, A., Giordano, A., Leggio, M., Menichini, G., Cristofaro, R. D., Moriconi, E., Cozzari, L., Farina, S. M., et al. (2007) · PubMed · Cited by 10
Homocysteine, B Vitamins, and Cardiovascular Risk
Ntaios, G. (2015) · Elsevier eBooks · doi:10.1016/b978-0-12-418680-4.00029-4 · Cited by 10
Homocysteine as a new risk factor for cardiovascular events in heart failure
Kardeşoğlu, E., Uz, Ö., Işılak, Z., & Cebeci, B. S. (2010) · International Journal of Cardiology · doi:10.1016/j.ijcard.2010.10.005 · Cited by 10
Is At Least One Vitamin Helping Our Vasculature?
Schulz, E., Steven, S., & Münzel, T. F. (2014) · Hypertension · doi:10.1161/hypertensionaha.114.04118 · Cited by 10
Homocysteine, B vitamins, and the risk of dementia
Clarke, R. (2007) · American Journal of Clinical Nutrition · doi:10.1093/ajcn/85.2.329 · Cited by 10
Gunnala, S., Buhlman, L. M., & Jadavji, N. M. (2025) · Nutrients · doi:10.3390/nu17071286 · Cited by 9
The dos, don'ts, and nuances of thrombophilia testing
Chiasakul, T., & Bauer, K. A. (2023) · Hematology · doi:10.1182/hematology.2023000491 · Cited by 9
Aarsetøy, H., Valente, E. J., Reine, A., Mansoor, M. A., Grundt, H., & Nilsen, D. W. T. (2007) · European Journal of Clinical Nutrition · doi:10.1038/sj.ejcn.1602701 · Cited by 9
Pexa, A., Herrmann, M., Taban‐Shomal, O., Henle, T., & Deußen, A. (2009) · Acta Physiologica · doi:10.1111/j.1748-1716.2009.01981.x · Cited by 9
Tobin, K. A. R., Holven, K. B., Retterstøl, K., Strøm, E., Ose, L., Aukrust, P., & Nenseter, M. S. (2009) · British Journal Of Nutrition · doi:10.1017/s0007114509991048 · Cited by 9
Folic acid supplementation reduces plasma homocysteine in postmenopausal women
Almassinokiani, F., Kashanian, M., Akbari, P., Mossayebi, E., & Sadeghian, E. (2016) · Journal of Obstetrics and Gynaecology · doi:10.3109/01443615.2015.1091811 · Cited by 9
Mandaviya, P. R., Aïssi, D., Dekkers, K. F., Joehanes, R., Kasela, S., Trương, V., Stolk, L., van Heemst, D., Ikram, M. A., Lindemans, J. W., et al. (2017) · Epigenomics · doi:10.2217/epi-2017-0038 · Cited by 9
Jin, S., Li, X., Wang, Y., Zhang, Y., Wu, Q., Zhang, L., Zuo, X.-B., Gao, J., & Li, J. (2019) · Chinese Medical Journal · doi:10.1097/cm9.0000000000000159 · Cited by 9
Cardiovascular health, risks and diseases in contemporary China
Cheng, T. O. (2011) · International Journal of Cardiology · doi:10.1016/j.ijcard.2011.08.011 · Cited by 9
Homocysteine, Cystatin C and N-Terminal-Pro Brain Natriuretic Peptide
Nilsson, K. H., Gustafson, L., & Hultberg, B. L. (2007) · Dementia and Geriatric Cognitive Disorders · doi:10.1159/000111994 · Cited by 9
Connolly, G. M., Cunningham, R., Mcnamee, P. T., Young, I. S., & Maxwell, A. P. (2009) · Nephron Clinical Practice · doi:10.1159/000242443 · Cited by 9
Folic Acid Supplementation and Cardiac and Stroke Mortality among Hemodialysis Patients
Leung, J., Larive, B., Dwyer, J. T., Hibberd, P. L., Jacques, P. F., & Rand, W. (2010) · Journal of Renal Nutrition · doi:10.1053/j.jrn.2010.01.005 · Cited by 9
Nilsson, K. H., Gustafson, L., & Hultberg, B. L. (2009) · Dementia and Geriatric Cognitive Disorders · doi:10.1159/000193628 · Cited by 9
Whayne, T. F. (2010) · Cardiovascular Therapeutics · doi:10.1111/j.1755-5922.2009.00101.x · Cited by 9
Acute myocardial infarction in a young male wrestler: A case report.
Poorzand, H., Esfehani, R. J., Hosseinzadeh, P., & Vojdanparast, M. (2015) · PubMed Central · Cited by 9
ST Segment Elevation Acute Myocardial Infarction and Complications of Myocardial Infarction
Anderson, J. L. (2012) · Elsevier eBooks · doi:10.1016/b978-1-4377-1604-7.00073-7 · Cited by 9
Micronutrient Vitamin Deficiencies and Cardiovascular Disease Risk: Advancing Current Understanding
Ekpenyong, C. E. (2017) · European Journal of Preventive Medicine · doi:10.11648/j.ejpm.20170501.11 · Cited by 9
Husemoen, L. L. N., Skaaby, T., Thuesen, B. H., Grarup, N., Sandholt, C. H., Hansen, T. F., Pedersen, O. B., & Linneberg, A. R. (2016) · European Journal of Clinical Nutrition · doi:10.1038/ejcn.2016.5 · Cited by 9
Vitamin D and Cardiovascular Disease
Reis, J. P., & Lutsey, P. L. (2012) · Oxidative stress and disease · doi:10.1201/b13714-20 · Cited by 9
The dubious use of vitamin-mineral supplements in relation to cardiovascular disease
McCormick, D. B. (2006) · American Journal of Clinical Nutrition · doi:10.1093/ajcn/84.4.680 · Cited by 9
The Heart of Drug Discovery and Development: Rational Target Selection
Spector, R., & Vesell, E. S. (2006) · Pharmacology · doi:10.1159/000093166 · Cited by 10
Serum folate is associated with coronary heart disease independently of homocysteine in Turkish men
Onat, A., Hergenç, G., Küçükdurmaz, Z., Can, G., Ayhan, E., & Bulur, S. (2008) · Clinical Nutrition · doi:10.1016/j.clnu.2008.06.009 · Cited by 9
Hultberg, M., & Hultberg, B. L. (2006) · Chemico-Biological Interactions · doi:10.1016/j.cbi.2006.10.009 · Cited by 9
Global Trends in Cardiovascular Disease
Khan, U., Rafiq, A., & Bella, J. N. (2016) · Elsevier eBooks · doi:10.1016/b978-0-12-803678-5.00056-4 · Cited by 10
Ischaemic Stroke and Transient Ischaemic Attack
Ringleb, P. A., Bousser, M., Ford, G. A., Bath, P. M., Brainin, M., Caso, V., Cervera, Á., Chamorro, Á., Cordonnier, C., Csiba, L., et al. (2010) · Wiley eBooks · doi:10.1002/9781444328394.ch9 · Cited by 9
Behzadi, P., & Hilaire, C. S. (2024) · American Journal of Physiology-Heart and Circulatory Physiology · doi:10.1152/ajpheart.00267.2024 · Cited by 8
Hoe ‘community-based’ werkt de huisarts?
de Bakker, D. H. (2006) · Huisarts en Wetenschap · doi:10.1007/bf03084773 · Cited by 8
Effects of L-Isoleucine and L-Valine on Hot Flushes and Serum Homocysteine
Guttuso, T. J., McDermott, M., Su, H., & Kieburtz, K. D. (2008) · Obstetrics and Gynecology · doi:10.1097/aog.0b013e31817d53b6 · Cited by 8
Acute Myocardial Infarction in a Young Man with Hyperhomocysteinemia and Pulmonary Tuberculosis
Ren, M., Zhang, C., Zhang, X., & Zhong, J. (2016) · Internal Medicine · doi:10.2169/internalmedicine.55.4565 · Cited by 8
Roca, B., Bennasar, M., Ferrero, J., Del, M., & Resino, E. (2012) · Swiss Medical Weekly · doi:10.4414/smw.2012.13323 · Cited by 8
Baghersalimi, A., Kolachahi, H. H., Darbandi, B., Mavardiani, Z. K., Alinodehi, M. A., Dalili, S., & Rad, A. H. (2018) · Journal of Pediatric Hematology/Oncology · doi:10.1097/mph.0000000000001295 · Cited by 8
Deficiency of B vitamins leads to cholesterol-independent atherogenic transformation of the aorta
Almer, G., Opriessnig, P., Wolinski, H., Sommer, G., Diwoky, C., Lechleitner, M., Kolb, D., Bubalo, V., Brunner, M. S., Schwarz, A. N., et al. (2022) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2022.113640 · Cited by 8
Clinical Manifestations of Vitamin B-12 Deficiency
Reenan, J. (2006) · The AMA Journal of Ethic · doi:10.1001/virtualmentor.2006.8.6.cprl1-0606 · Cited by 8
Combination of biomarkers to predict mortality in elderly patients with myocardial infarction
Olivieri, F., Spazzafumo, L., Antonicelli, R., Marchegiani, F., Cardelli, M., Sirolla, C., Galeazzi, R., Giovagnetti, S., Mocchegiani, E., & Franceschi, C. (2008) · Mechanisms of Ageing and Development · doi:10.1016/j.mad.2008.01.002 · Cited by 8
Hypertension in spontaneously hypertensive rats occurs despite low plasma levels of homocysteine
Kondziella, D., Zetterberg, H., Haugen, E., & Fu, M. (2008) · Physiological Research · doi:10.33549/physiolres.931181 · Cited by 8
García‐Pinilla, J. M., Caliani, S. E., Gómez‐Doblas, J. J., Jiménez-Navarro, M. F., Gaitán-Arroyo, M. J., Muñoz‐Morán, E., Cabrera‐Bueno, F., Hernández-García, J. M., Ortega-Jiménez, M. V., Ruiz‐Galdón, M., et al. (2006) · International Journal of Cardiology · doi:10.1016/j.ijcard.2006.06.053 · Cited by 8
Lupus Anticoagulant and Anticardiolipin Antibodies in Serum of Patients Treated With Risperidone
Schwartz, M., Kormilachev, M., Kushnir, M., Weller, B., Rochas, M., & Toubi, E. (2009) · The Journal of Clinical Psychiatry · doi:10.4088/jcp.08l04572 · Cited by 8
O'Neill, B. (2010) · Bioscience Horizons The International Journal of Student Research · doi:10.1093/biohorizons/hzq022 · Cited by 8
Rational Medical Therapy Is the Key to Effective Cardiovascular Disease Prevention
Spence, J. D. (2017) · Canadian Journal of Cardiology · doi:10.1016/j.cjca.2017.01.003 · Cited by 8
Knapik, J. J., Jean, R. T., Austin, K. G., Steelman, R. A., Gannon, J., Farina, E. K., & Lieberman, H. R. (2016) · Nutrition Research · doi:10.1016/j.nutres.2016.09.001 · Cited by 8
González, J. M., Millán, E. R., Julve, J., & Blanco‐Vaca, F. (2010) · Revista de Neurología · doi:10.33588/rn.5004.2009081 · Cited by 8
Pathogenesis of Alzheimer disease
Pavlović, D. M., Pavlovic, A. M., & Zugic, S. (2007) · Vojnosanitetski pregled · doi:10.2298/vsp0711765p · Cited by 8
Mesna for Treatment of Hyperhomocysteinemia in Hemodialysis Patients
Urquhart, B. L., Freeman, D. J., Cutler, M. J., Mainra, R., Spence, J. D., & House, A. A. (2008) · Clinical Journal of the American Society of Nephrology · doi:10.2215/cjn.04771107 · Cited by 8
Muszkat, M., Bialer, O., Blotnick, S., Adar, L., Xie, H., Ufer, M., Cascorbi, I., & Caraco, Y. (2010) · Clinical Therapeutics · doi:10.1016/j.clinthera.2010.02.008 · Cited by 8
Shammas, N. W., Dippel, E. J., Jerin, M. J., Toth, P. P., Kapalis, M. J., Reddy, M., & Harb, H. (2008) · Preventive Cardiology · doi:10.1111/j.1751-7141.2008.08293.x · Cited by 8
Increased homocysteine in heart failure: a result of renal impairment?
Aksoy, N., Aksoy, M. F., Çakmak, M., Gergerlioğlu, H. S., Davutoğlu, V., Soydinç, S., & Meram, İ. (2006) · Clinical Chemistry and Laboratory Medicine (CCLM) · doi:10.1515/cclm.2006.245 · Cited by 8
van Oijen, M. G. H., Laheij, R. J. F., Jansen, J. B. �. �., & Verheugt, F. W. A. (2007) · Netherlands Heart Journal · doi:10.1007/bf03086002 · Cited by 8
Sanz, J., Moreno, P., & Fuster, V. (2007) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2006.11.050 · Cited by 8
Metadata
- Authors
- Bønaa, K. H., Njølstad, I., Ueland, P. M., Schirmer, H., Tverdal, A., Steigen, T., Wang, H., Nordrehaug, J. E., Arnesen, E., & Rasmussen, K.
- Affiliations
- UiT The Arctic University of Norway (NO)
- University of Bergen (NO)
- Norwegian Institute of Public Health (NO)
- University Hospital of North Norway (NO)
- Haukeland University Hospital (NO)
- ORCID
- Venue
- New England Journal of Medicine
- Publisher
- Massachusetts Medical Society
- Published
- 2006-04-13
- Volume
- 354
- Issue
- 15
- Pages
- 1578-1588
- ISSN
- 0028-4793 (ISSN-L)
- 1533-4406
- OpenAlex
- W2115135910
- Cited by
- 1,442
- References
- 41
- Citations by year
- 2026: 22 · 2025: 25 · 2024: 27 · 2023: 29 · 2022: 17 · 2021: 25 · 2020: 28 · 2019: 26 · 2018: 33 · 2017: 49 · 2016: 48 · 2015: 52 · 2014: 61 · 2013: 68 · 2012: 97
- FWCI
- 134.58
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- New England Journal of Medicine (publishedVersion)
- PubMed (publishedVersion)
- Funders
- Universitetet i Tromsø
- European Society of Cardiology
- Norges Forskningsråd
- Helse Nord RHF
- Topics
- Health Sciences › Nursing › Nutrition and Dietetics › Folate and B Vitamins Research
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Acute Myocardial Infarction Research
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Lipoproteins and Cardiovascular Health
- Keywords
- homocysteine, acute myocardial infarction, B vitamins, folic acid, vitamin B12, vitamin B6, secondary prevention, cardiovascular events, reinfarction, stroke, sudden cardiac death, hyperhomocysteinemia
- MeSH terms
- Adult, Aged, Aged, 80 and over, Double-Blind Method, Drug Therapy, Combination, Female, Folic Acid, Humans, Male, Middle Aged, Myocardial Infarction, Vitamin B 12, Proportional Hazards Models, Death, Sudden, Cardiac, Hyperhomocysteinemia, Stroke, Vitamin B 6, Secondary Prevention
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
