The DOI matches its Crossref record; 5 of the 5 references it cites were found in a registry or an index.
Severe Anemia in Malawian Children
Open accessAbstract
BACKGROUND: Severe anemia is a major cause of sickness and death in African children, yet the causes of anemia in this population have been inadequately studied. METHODS: We conducted a case-control study of 381 preschool children with severe anemia (hemoglobin concentration, <5.0 g per deciliter) and 757 preschool children without severe anemia in urban and rural settings in Malawi. Causal factors previously associated with severe anemia were studied. The data were examined by multivariate analysis and structural equation modeling. RESULTS: deficiency (adjusted odds ratio, 2.2; 95% CI, 1.4 to 3.6) were associated with severe anemia. Folate deficiency, sickle cell disease, and laboratory signs of an abnormal inflammatory response were uncommon. Iron deficiency was not prevalent in case patients (adjusted odds ratio, 0.37; 95% CI, 0.22 to 0.60) and was negatively associated with bacteremia. Malaria was associated with severe anemia in the urban site (with seasonal transmission) but not in the rural site (where malaria was holoendemic). Seventy-six percent of hookworm infections were found in children under 2 years of age. CONCLUSIONS: There are multiple causes of severe anemia in Malawian preschool children, but folate and iron deficiencies are not prominent among them. Even in the presence of malaria parasites, additional or alternative causes of severe anemia should be considered.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Weiss, G., & Goodnough, L. T. (2005) · New England Journal of Medicine · doi:10.1056/nejmra041809 · Cited by 3,800
Estimating the population attributable risk for multiple risk factors using case-control data.
BRUZZI, P., GREEN, S. B., BYAR, D. P., BRINTON, L. A., & SCHAIRER, C. (1985) · American Journal of Epidemiology · doi:10.1093/oxfordjournals.aje.a114174 · Cited by 1,214
Regulation of ferritin genes and protein
Torti, F. M., & Torti, S. V. (2002) · Blood · doi:10.1182/blood.v99.10.3505 · Cited by 1,173
Sazawal, S., Black, R. E., Ramsan, M., Chwaya, H. M., Stoltzfus, R. J., Dutta, A., Dhingra, U., Kabole, I., Deb, S., Othman, M. K., et al. (2006) · The Lancet · doi:10.1016/s0140-6736(06)67962-2 · Cited by 981
Serum Transferrin Receptor and Its Ratio to Serum Ferritin in the Diagnosis of Iron Deficiency
Punnonen, K., Irjala, K., & Rajamäki, A. (1997) · Blood · doi:10.1182/blood.v89.3.1052 · Cited by 859
Cited by
Retinoic acid receptors: From molecular mechanisms to cancer therapy
di Masi, A., Leboffe, L., De Marinis, E., Pagano, F., Cicconi, L., Rochette-Egly, C., Lo-Coco, F., Ascenzi, P., & Nervi, C. (2015) · Molecular Aspects of Medicine · doi:10.1016/j.mam.2014.12.003 · Cited by 403
Uche, I. V., MacLennan, C. A., & Saul, A. (2017) · PLOS Neglected Tropical Diseases · doi:10.1371/journal.pntd.0005118 · Cited by 232
Iron, anemia and hepcidin in malaria
Spottiswoode, N., Duffy, P. E., & Drakesmith, H. (2014) · Frontiers in Pharmacology · doi:10.3389/fphar.2014.00125 · Cited by 127
Adamu, A. L., Crampin, A., Kayuni, N., Amberbir, A., Koole, O., Phiri, A., Nyirenda, M., & Fine, P. (2017) · Population Health Metrics · doi:10.1186/s12963-017-0128-2 · Cited by 114
Self-citationIron status predicts malaria risk in Malawian preschool children
Jonker, F. A. M., Calis, J. C. J., van Hensbroek, M. B., Phiri, K., Geskus, R. B., Brabin, B. J., & Leenstra, T. (2012) · PLoS ONE · doi:10.1371/journal.pone.0042670 · Cited by 77
Self-citationDe Mast, Q., Van Dongen‐Lases, E. C., Swinkels, D. W., Nieman, A., Roestenberg, M., Druilhe, P., Arens, T. A., Luty, A. J., Hermsen, C. C., Sauerwein, R. W., et al. (2009) · British Journal of Haematology · doi:10.1111/j.1365-2141.2009.07664.x · Cited by 74
Esan, M. O., van Hensbroek, M. B., Nkhoma, E., Musicha, C., White, S. A., ter Kuile, F. O., & Phiri, K. S. (2013) · Clinical Infectious Diseases · doi:10.1093/cid/cit528 · Cited by 69
Self-citationHepcidin demonstrates a biphasic association with anemia in acute Plasmodium falciparum malaria
Casals-Pascual, C., Huang, H., Lakhal-Littleton, S., Thezenas, M. L., Kai, O., Newton, C. R. J. C., & Roberts, D. J. (2012) · Haematologica · doi:10.3324/haematol.2012.065854 · Cited by 47
Jonker, F. A. M., Calis, J. C. J., Phiri, K., Kraaijenhagen, R. J., Brabin, B. J., Faragher, B., Wiegerinck, E. T., Tjalsma, H., Swinkels, D. W., & Boele van Hensbroek, M. (2013) · PLoS ONE · doi:10.1371/journal.pone.0078964 · Cited by 42
Silver, K. L., Conroy, A. L., Leke, R. G. F., Leke, R. J. I., Gwanmesia, P., Molyneux, M. E., Wallace, D. T., Rogerson, S. J., & Kain, K. C. (2011) · PLoS ONE · doi:10.1371/journal.pone.0024985 · Cited by 43
Self-citationMikomangwa, W. P., Minzi, O., Mutagonda, R., Baraka, V., Mlugu, E. M., Aklillu, E., & Kamuhabwa, A. A. R. (2020) · Malaria Journal · doi:10.1186/s12936-020-03234-4 · Cited by 36
(2012) · doi:10.5772/31289 · Cited by 29
Metadata
- Authors
- Calis, J. C. J., Phiri, K. S., Faragher, E. B., Brabin, B. J., Bates, I., Cuevas, L. E., de Haan, R. J., Phiri, A. I., Malange, P., Khoka, M., Hulshof, P. J. M., van Lieshout, L., Beld, M. G. H. M., Teo, Y. Y., Rockett, K. A., Richardson, A., Kwiatkowski, D. P., Molyneux, M. E., & van Hensbroek, M. B.
- Venue
- New England Journal of Medicine
- Publisher
- Massachusetts Medical Society
- Published
- 2008-02-28
- Volume
- 358
- Issue
- 9
- Pages
- 888-899
- ISSN
- 0028-4793 (ISSN-L)
- 1533-4406
- OpenAlex
- W2103173032
- Cited by
- 492
- References
- 5
- FWCI
- 17.36
- Type
- journal article
- Language
- en
- Open access
- bronze
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
