Irbesartan in Patients with Heart Failure and Preserved Ejection Fraction

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1. Connecting Heart Failure with Preserved Ejection Fraction and Renal Dysfunction: The Role of endothelial Dysfunction and Inflammation
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3. A Comprehensive Population-Based Characterization of Heart Failure with Mid-Range Ejection Fraction
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4. Longitudinal Changes in Ejection Fraction in Heart Failure Patients With Preserved and Reduced Ejection Fraction
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5. Upstream therapies for management of atrial fibrillation: review of clinical evidence and implications for European Society of Cardiology guidelines. Part I: primary prevention
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6. Angiotensin Receptor Neprilysin Inhibition in Heart Failure With Preserved Ejection Fraction
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7. Identifying Pathophysiological Mechanisms in Heart Failure With Reduced Versus Preserved Ejection Fraction
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8. A transcatheter intracardiac shunt device for heart failure with preserved ejection fraction (REDUCE LAP-HF): a multicentre, open-label, single-arm, phase 1 trial
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9. Mortality associated with heart failure with preserved vs. reduced ejection fraction in a prospective international multi-ethnic cohort study
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10. Heart failure with preserved ejection fraction: everything the clinician needs to know
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11. Rationale and design of the Treatment of Preserved Cardiac Function Heart Failure with an Aldosterone Antagonist Trial: A randomized, controlled study of spironolactone in patients with symptomatic heart failure and preserved ejection fraction
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12. Characterization of Subgroups of Heart Failure Patients with Preserved Ejection Fraction with Possible Implications for Prognosis and Treatment Response
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13. Effects of blood pressure lowering on outcome incidence in hypertension
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14. Metabolomic Profiling Identifies Novel Circulating Biomarkers of Mitochondrial Dysfunction Differentially Elevated in Heart Failure With Preserved Versus Reduced Ejection Fraction: Evidence for Shared Metabolic Impairments in Clinical Heart Failure
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15. Heart Failure With Normal Left Ventricular Ejection Fraction
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16. Exercise Intolerance in Heart Failure With Preserved Ejection Fraction
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17. Factors Associated With Outcome in Heart Failure With Preserved Ejection Fraction
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18. Prognostic Value of Baseline Plasma Amino-Terminal Pro-Brain Natriuretic Peptide and Its Interactions With Irbesartan Treatment Effects in Patients With Heart Failure and Preserved Ejection Fraction
    Inder S. Anand, Thomas S. Rector, John G.F. Cleland, Michael A. Kuskowski, Robert Samuel McKelvie, Hans Persson, John J.V. McMurray, Michael R. Zile, Michel Komajda N, Barry M. Massie et al. · 2011 · Circulation Heart Failure
19. Irbesartan in Patients with Atrial Fibrillation
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20. Understanding the Epidemic of Heart Failure: Past, Present, and Future
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21. Chronic Heart Failure: Contemporary Diagnosis and Management
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22. Treatment of Heart Failure With Normal Ejection Fraction
    Walter J. Paulus, Joris J.M. van Ballegoij · 2010 · Journal of the American College of Cardiology
23. CMR-Verified Diffuse Myocardial Fibrosis Is Associated With Diastolic Dysfunction in HFpEF
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24. Abdominal Obesity Is Associated With an Increased Risk of All-Cause Mortality in Patients With HFpEF
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25. Multidisciplinary Cardiac Rehabilitation and Long-Term Prognosis in Patients With Heart Failure
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26. Sex Differences in Clinical Characteristics and Outcomes in Elderly Patients With Heart Failure and Preserved Ejection Fraction
    Carolyn S.P. Lam, Peter E. Carson, Inder S. Anand, Thomas S. Rector, Michael A. Kuskowski, Michel Komajda N, Robert Samuel McKelvie, John J.V. McMurray, Michael R. Zile, Barry M. Massie et al. · 2012 · Circulation Heart Failure
27. Frailty and multiple comorbidities in the elderly patient with heart failure: implications for management
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28. Sex Differences in Heart Failure With Preserved Ejection Fraction
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29. The Middle Child in Heart Failure: Heart Failure with Mid-Range Ejection Fraction (40–50%)
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30. Plasma Biomarkers That Reflect Determinants of Matrix Composition Identify the Presence of Left Ventricular Hypertrophy and Diastolic Heart Failure
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31. Recovered Heart Failure with Reduced Ejection Fraction and Outcomes: A Prospective Study
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32. Biological Phenotypes of Heart Failure With Preserved Ejection Fraction
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33. Comorbidity of atrial fibrillation and heart failure
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34. Results of the Randomized Aldosterone Antagonism in Heart Failure With Preserved Ejection Fraction Trial (RAAM-PEF)
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35. How do Patients with Heart Failure with Preserved Ejection Fraction Die?
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36. Cardiac Imaging to Evaluate Left Ventricular Diastolic Function
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37. Effects of the Long-Term Administration of Nebivolol on the Clinical Symptoms, Exercise Capacity, and Left Ventricular Function of Patients with Diastolic Dysfunction: Results of the ELANDD Study
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38. The 2012 Canadian Cardiovascular Society Heart Failure Management Guidelines Update: Focus on Acute and Chronic Heart Failure
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39. Prognostic Importance of Pathophysiologic Markers in Patients With Heart Failure and Preserved Ejection Fraction
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40. Effects of blood-pressure-lowering treatment on outcome incidence in hypertension: 10 – Should blood pressure management differ in hypertensive patients with and without diabetes mellitus? Overview and meta-analyses of randomized trials
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41. The Renin-Angiotensin-Aldosterone System and Heart Failure
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42. A Systems BIOlogy Study to TAilored Treatment in Chronic Heart Failure: Rationale, Design, and Baseline Characteristics of BIOSTAT-CHF
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43. Clinical and Echocardiographic Characteristics and Cardiovascular Outcomes According to Diabetes Status in Patients With Heart Failure and Preserved Ejection Fraction: A Report From the I-Preserve Trial (Irbesartan in Heart Failure With Preserved Ejection Fraction)
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44. Patient Phenotype Profiling in Heart Failure with Preserved Ejection Fraction to Guide Therapeutic Decision Making. A Scientific Statement of the Heart Failure Association, the European Heart Rhythm Association of the European Society of Cardiology, and the European Society of Hypertension
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45. JCS/JHFS 2025 Guideline on Diagnosis and Treatment of Heart Failure
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46. Sex Differences in Outcomes and Responses to Spironolactone in Heart Failure With Preserved Ejection Fraction
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47. Heart failure with preserved ejection fraction: a clinical dilemma
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48. The HFpEF Obesity Phenotype
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49. Cardiac fibrosis: potential therapeutic targets
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50. Role of endothelial dysfunction in heart failure
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51. Heart Failure With Preserved Ejection Fraction: Heterogeneous Syndrome, Diverse Preclinical Models
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52. JCS/JHFS 2021 Guideline Focused Update on Diagnosis and Treatment of Acute and Chronic Heart Failure
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53. Heart Failure in Elderly Patients: Distinctive Features and Unresolved Issues
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54. Role of inflammation in the pathogenesis of heart failure with preserved ejection fraction and its potential as a therapeutic target
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55. Renal Effects of the Angiotensin Receptor Neprilysin Inhibitor LCZ696 in Patients with Heart Failure and Preserved Ejection Fraction
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56. β-Arrestin–Biased Agonism of the Angiotensin Receptor Induced by Mechanical Stress
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57. Effects of telmisartan, irbesartan, valsartan, candesartan, and losartan on cancers in 15 trials enrolling 138 769 individuals
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58. Heart Failure With Mid-Range (Borderline) Ejection Fraction
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59. Heart Failure With Recovered Ejection Fraction: A Distinct Clinical Entity
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61. Baseline Characteristics of Patients in the Treatment of Preserved Cardiac Function Heart Failure With an Aldosterone Antagonist Trial
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63. RAnoLazIne for the Treatment of Diastolic Heart Failure in Patients With Preserved Ejection Fraction
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64. What Have We Learned About Patients With Heart Failure and Preserved Ejection Fraction From DIG-PEF, CHARM-Preserved, and I-PRESERVE?
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66. Association of β-Blocker Use With Heart Failure Hospitalizations and Cardiovascular Disease Mortality Among Patients With Heart Failure With a Preserved Ejection Fraction
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67. Association Between Use of Renin-Angiotensin System Antagonists and Mortality in Patients With Heart Failure and Preserved Ejection Fraction
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68. Medical Therapy for Heart Failure Caused by Ischemic Heart Disease
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69. The Comparative Efficacy and Safety of the Angiotensin Receptor Blockers in the Management of Hypertension and Other Cardiovascular Diseases
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70. Ranolazine Improves Cardiac Diastolic Dysfunction Through Modulation of Myofilament Calcium Sensitivity
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71. Interaction Between Spironolactone and Natriuretic Peptides in Patients With Heart Failure and Preserved Ejection Fraction
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72. Therapeutic targets for cardiac fibrosis: from old school to next-gen
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73. Circulating microRNAs as Candidate Markers to Distinguish Heart Failure in Breathless Patients
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74. Inflammatory Biomarkers Predict Heart Failure Severity and Prognosis in Patients With Heart Failure With Preserved Ejection Fraction
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75. The Frailty Syndrome and Outcomes in the TOPCAT Trial
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76. III Diretriz Brasileira de Insuficiência Cardíaca Crônica
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77. Epidemiology, Pathophysiology, Diagnosis and Treatment of Heart Failure in Diabetes
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80. Heart failure with preserved ejection fraction in Asia
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81. Prognostic Value of Cardiopulmonary Exercise Testing in Heart Failure With Reduced, Midrange, and Preserved Ejection Fraction
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82. Pulsatile arterial haemodynamics in heart failure
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83. The Novel Biomarker Growth Differentiation Factor 15 in Heart Failure with Normal Ejection Fraction
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86. Histone deacetylase activity governs diastolic dysfunction through a nongenomic mechanism
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87. Heart Failure With Preserved Ejection Fraction
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88. JCS/JHFS 2021 Guideline Focused Update on Diagnosis and Treatment of Acute and Chronic Heart Failure
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89. Sacubitril–valsartan as a treatment for apparent resistant hypertension in patients with heart failure and preserved ejection fraction
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90. Heart failure with preserved ejection fraction in the elderly: scope of the problem
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91. Baseline Characteristics of Patients With Heart Failure and Preserved Ejection Fraction in the PARAGON-HF Trial
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95. Left Atrial Systolic and Diastolic Dysfunction in Heart Failure with Normal Left Ventricular Ejection Fraction
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96. Heart Failure With Mid-Range Ejection Fraction: A Distinct Clinical Entity? Insights From The Trial of Intensified Versus Standard Medical Therapy in Elderly Patients With Congestive Heart Failure (TIME-CHF)
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97. Complex Energy Metabolic Changes in Heart Failure With Preserved Ejection Fraction and Heart Failure With Reduced Ejection Fraction
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98. Drug treatment effects on outcomes in heart failure with preserved ejection fraction: a systematic review and meta-analysis
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99. Left Atrial Function Predicts Heart Failure Hospitalization in Subjects With Preserved Ejection Fraction and Coronary Heart Disease
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100. Heart Failure with Preserved Ejection Fraction: Uncertainties and Dilemmas
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