Cited by 635Thyroid Disorders and TreatmentsMaternal Mental Health During Pregnancy and PostpartumThyroid Cancer Diagnosis and Treatment

The DOI matches its Crossref record; 18 of the 18 references it cites were found in a registry or an index.

Antenatal Thyroid Screening and Childhood Cognitive Function

Open access

Lazarus, John H., Bestwick, Jonathan P., Channon, Sue, Paradice, Ruth, Maina, Aldo, Rees, Rhian, Chiusano, Elisabetta, John, Rhys, Guaraldo, Varvara, George, Lynne M., Perona, Marco, Dall'Amico, Daniela, Parkes, Arthur B., Joomun, Mohammed, Wald, Nicholas J.·2012·New England Journal of Medicine

DOI 10.1056/nejmoa1106104PMC PMC3814060

Open this paper in CoChat — free account Open PDF

Abstract

BACKGROUND: Children born to women with low thyroid hormone levels have been reported to have decreased cognitive function. METHODS: We conducted a randomized trial in which pregnant women at a gestation of 15 weeks 6 days or less provided blood samples for measurement of thyrotropin and free thyroxine (T(4)). Women were assigned to a screening group (in which measurements were obtained immediately) or a control group (in which serum was stored and measurements were obtained shortly after delivery). Thyrotropin levels above the 97.5th percentile, free T(4) levels below the 2.5th percentile, or both were considered a positive screening result. Women with positive findings in the screening group were assigned to 150 μg of levothyroxine per day. The primary outcome was IQ at 3 years of age in children of women with positive results, as measured by psychologists who were unaware of the group assignments. RESULTS: Of 21,846 women who provided blood samples (at a median gestational age of 12 weeks 3 days), 390 women in the screening group and 404 in the control group tested positive. The median gestational age at the start of levothyroxine treatment was 13 weeks 3 days; treatment was adjusted as needed to achieve a target thyrotropin level of 0.1 to 1.0 mIU per liter. Among the children of women with positive results, the mean IQ scores were 99.2 and 100.0 in the screening and control groups, respectively (difference, 0.8; 95% confidence interval [CI], -1.1 to 2.6; P=0.40 by intention-to-treat analysis); the proportions of children with an IQ of less than 85 were 12.1% in the screening group and 14.1% in the control group (difference, 2.1 percentage points; 95% CI, -2.6 to 6.7; P=0.39). An on-treatment analysis showed similar results. CONCLUSIONS: Antenatal screening (at a median gestational age of 12 weeks 3 days) and maternal treatment for hypothyroidism did not result in improved cognitive function in children at 3 years of age. (Funded by the Wellcome Trust UK and Compagnia di San Paulo, Turin; Current Controlled Trials number, ISRCTN46178175.).

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

Integrity signals

Registry

Crossref · 10.1056/nejmoa1106104

Cites

18 of 18 references verified0 citation errors · 0 not checkable

Statistics

Claims the paper makes

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Self-check

Percentages, sums and reported differences re-computed from the paper’s own numbers.

The self-check needs the paper’s full text.

Guidelines of the American Thyroid Association for the diagnosis and management of thyroid disease during pregnancy and postpartum
Stagnaro-Green, A., Abalovich, M., Alexander, E., Azizi, F., Mestman, J., Negro, R., Nixon, A., Pearce, E. N., Soldin, O. P., Sullivan, S., et al. (2011) · Thyroid · doi:10.1089/thy.2011.0087 · Cited by 2,942
Maternal thyroid deficiency during pregnancy and subsequent neuropsychological development of the child
Haddow, J. E., Palomaki, G. E., Allan, W. C., Williams, J. R., Knight, G. J., Gagnon, J., O'Heir, C. E., Mitchell, M. L., Hermos, R. J., Waisbren, S. E., et al. (1999) · New England Journal of Medicine · doi:10.1056/nejm199908193410801 · Cited by 2,558
Low maternal free thyroxine concentrations during early pregnancy are associated with impaired psychomotor development in infancy
Pop, V. J., Kuijpens, J. L. P., van Baar, A. L., Verkerk, G. J. M., van Son, M. J. M., de Vijlder, J. J. M., Vulsma, T., Wiersinga, W. M., Drexhage, H. A., & Vader, H. L. (1999) · Clinical Endocrinology · doi:10.1046/j.1365-2265.1999.00639.x · Cited by 1,006
Maternal hypothyroxinaemia during early pregnancy and subsequent child development: a 3‐year follow‐up study
Pop, V. J., Brouwers, E. P. M., Vader, H. L., Vulsma, T., van Baar, A. L., & de Vijlder, J. J. M. (2003) · Clinical Endocrinology · doi:10.1046/j.1365-2265.2003.01822.x · Cited by 727
Timing of thyroid hormone action in the developing brain: clinical observations and experimental findings
Zoeller, R. T., & Rovet, J. (2004) · Journal of Neuroendocrinology · doi:10.1111/j.1365-2826.2004.01243.x · Cited by 605
Maternal thyroid hormones early in pregnancy and fetal brain development
de Escobar, G. M., Obregón, M.-J., & del Rey, F. E. (2004) · Best Practice & Research Clinical Endocrinology & Metabolism · doi:10.1016/j.beem.2004.03.012 · Cited by 588
NEUROLOGICAL DAMAGE TO THE FETUS RESULTING FROM SEVERE IODINE DEFICIENCY DURING PREGNANCY
Pharoah, P. O. D., Buttfield, I. H., & Hetzel, B. S. (1971) · The Lancet · doi:10.1016/s0140-6736(71)91040-3 · Cited by 469
Maternal Thyroid Function during Early Pregnancy and Cognitive Functioning in Early Childhood: The Generation R Study
Henrichs, J., Bongers‐Schokking, J. J., Schenk, J. J., Ghassabian, A., Schmidt, H. G., Visser, T. J., Hooijkaas, H., Keizer‐Schrama, S. M. P. F. D. M., Albert Hofman, D., Jaddoe, V. V. W., et al. (2010) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2010-0415 · Cited by 468
Abnormalities of maternal thyroid function during pregnancy affect neuropsychological development of their children at 25–30 months
Li, Y., Shan, Z., Teng, W., Yu, X., Li, Y., Fan, C., Teng, X., Guo, R., Hong, W., Li, J., et al. (2009) · Clinical Endocrinology · doi:10.1111/j.1365-2265.2009.03743.x · Cited by 449
Delayed Neurobehavioral Development in Children Born to Pregnant Women with Mild Hypothyroxinemia During the First Month of Gestation: The Importance of Early Iodine Supplementation
Berbel, P. J., Mestre, J. L., Santamaría, A., Azorín, I. P., Franco, A., Graells, M., González-Torga, A., & de Escobar, G. M. (2009) · Thyroid · doi:10.1089/thy.2008.0341 · Cited by 363

Show all 18 references

Sorted by citations

Items 501–600 of 633

Thyroid Disease in Pregnancy
Bhatt, S. J., Pinho, G., & Morelli, S. S. (2019) · Topics in Obstetrics & Gynecology · doi:10.1097/01.pgo.0000615660.61696.20 · Cited by 1
Algunas consideraciones sobre el documento de consenso «Detección de la disfunción tiroidea en la población gestante: está justificado el cribado universal»
Giménez‐Pérez, G. (2013) · Endocrinología y Nutrición · doi:10.1016/j.endonu.2013.01.014 · Cited by 1
Mild thyroid dysfunction in pregnancy and children’s educational performance
Päkkilä, F. (2018) · BMJ · doi:10.1136/bmj.k636 · Cited by 1
Thyroid Function Among Pregnant Women Attending Antenatal Clinic At The Kenyatta National Hospital Principal Investigator
Mungla, P. A. (2017) · Cited by 1
Hypothyroidism and Pregnancy
Granfors, M. (2015) · Uppsala University Publications (Uppsala University) · Cited by 1
Pregnancy‐Induced Physiologic Alterations
Norwitz, E. R., & Robinson, J. N. (2018) · doi:10.1002/9781119129400.ch4 · Cited by 1
Screening of Thyroid Function in Pregnancy
Azizi, F. (2022) · Springer eBooks · doi:10.1007/978-3-030-98777-0_4 · Cited by 1
The on-going controversy of target thyroid stimulating hormone: Time for pragmatism
Wiles, K., Nana, M., & Nelson‐Piercy, C. (2025) · Obstetric Medicine · doi:10.1177/1753495x251395910 · Cited by 1
Protocol 21: Thyroid Disorders
Thung, S. (2015) · doi:10.1002/9781119001256.ch21
Praxisrelevante Entwicklungen 2011/2012 in der Thyreologie
Feldkamp, J. (2013) · Journal für Kardiologie (Krause & Pachernegg GmbH)
Subclinical Hypothyroidism and Accidental Hemorrhage
Hashim, B. A. (2014)
Faut-il dépister l’hypothyroïdie maternelle en début de grossesse chez une patiente n’ayant aucun antécédent de dysthyroïdie ?
Carcopino, X. (2012) · Revue de médecine périnatale · doi:10.1007/s12611-012-0171-y
Faut-il dépister systématiquement l’hypothyroïdie au cours de la grossesse ?
Roublev, A. (2012) · Option/Bio · doi:10.1016/s0992-5945(12)71188-1
Cribado universal del hipotiroidismo en la gestación. Comentarios al Protocolo SEGO 2013
Uriarte, J. M., de Guadiana‐Romualdo, L. G., Pérez, M. Á. J., Izquierdo, O. G., & Rivero, I. M. (2014) · Progresos de Obstetricia y Ginecología · doi:10.1016/j.pog.2013.10.002
New guidelines for the management of hypothyroidism
Vaidya, B. (2012) · Nature Reviews Endocrinology · doi:10.1038/nrendo.2012.226
Some considerations about the consensus document “Detection of thyroid dysfunction in pregnant women: Universal screening is justified”
Giménez‐Pérez, G. (2013) · Endocrinología y Nutrición (English Edition) · doi:10.1016/j.endoen.2013.01.014
Diagnosing Mild Thyroid Dysfunction in Early Pregnancy and Defining Its Impact on Complications of Pregnancy Needs to Be Revisited
Mestman, J. H. (2015) · Clinical Thyroidology · doi:10.1089/ct.2015;27.56-58
DEPISTAGE ET TRAITEMENT DE L'HYPOTHYROIDIE PENDANT LA GROSSESSE : UNE REVUE DE LA LITTERATURE
Friess, H. (2014)
Management of Thyroid Disease in Pregnancy: Before, During, and After
Alexander, E. K. (2015) · The Endocrine Society eBooks · doi:10.1210/mtp4.9781936704941.ch66
Hypothyroidism Complicating Pregnancy: A Local Perspective
Chor, C. M., & Tam, W. H. (2014) · Hong Kong Journal of Gynaecology Obstetrics and Midwifery
Hyperthyroidism during pregnancy — the role of measuring maternal TSH receptor antibodies and foetal ultrasound monitoring Nadczynność tarczycy w ciąży — rola oznaczania przeciwciał przeciwko receptorowi TSH i ultrasonograficznego monitorowania płodu
Dębska, M., & Kretowicz, P. (2014)
Maternal Iodine Status in Regions of Moderate or Mild Iodine Deficiency
Lazarus, J. H. (2014)
Self-citation
To screen or not to screen for subclinical hypothyroidism in pregnancy?
Freyne, A., & Byrne, B. (2013) · PubMed
A High Concentration of Perchlorate in the Blood of Pregnant Women Correlates with Low Verbal IQ in Their 3-Year-Old Offspring
Burger, A. (2014) · Clinical Thyroidology · doi:10.1089/ct.2014;26.262-263
Nouveau-nés de mères dysthyroïdiennes : impact de la mise en place d'un protocole en maternité. L'expérience amiénoise
Cauliez, A. (2015) · HAL
No Improvement in Childhood IQ With Antenatal Thyroid Screening
(2012) · AAP Grand Rounds · doi:10.1542/gr.27-5-54
Antenatal Thyroid Screening and Childhood Cognitive Function
Thiel, A., & Schott, M. (2012) · Yearbook of Endocrinology · doi:10.1016/j.yend.2012.05.032
Antenatal Thyroid Screening and Childhood Cognitive Function
Dungan, J. S. (2012) · Yearbook of Obstetrics Gynecology and Women s Health · doi:10.1016/j.yobg.2012.06.163
Antenatal Thyroid Screening and Childhood Cognitive Function
SHULMAN, L. P. (2012) · Yearbook of Obstetrics Gynecology and Women s Health · doi:10.1016/j.yobg.2012.05.036
Une heureuse TSH
Richard, T. (2014)
Thyroid Hormones, Iodine and Iodides and Antithyroid Drugs
Bilder, G. E. (2014) · Side effects of drugs annual · doi:10.1016/b978-0-444-63407-8.00041-1
Hypothyroidism in Pregnancy: Review
Eraydın, A., & Akarsu, E. (2016) · Turkiye Klinikleri Journal of Endocrinology · doi:10.5336/endocrin.2015-47689
A New Modifiable Risk Factor for Schizophrenia?
Tiemeier, H. W., & Korevaar, T. I. M. (2016) · Biological Psychiatry · doi:10.1016/j.biopsych.2016.04.004
Reply
Casey, B. M. (2015) · American Journal of Obstetrics and Gynecology · doi:10.1016/j.ajog.2015.01.003
Risk stratification for women undergoing in-vitro fertilisation treatment
Dhillon‐Smith, R. K. (2016) · University of Birmingham Institutional Research Archive (University of Birmingham)
Schildklierdisfunctie bij zwangeren: klinische dilemma's
Vissenberg, R., Goddijn, M., Mol, B. W., van der Post, J., Fliers, E., & Bisschop, P. H. L. T. (2012) · Data Archiving and Networked Services (DANS)
Guías de práctica clínica para el tratamiento del hipotiroidismo
Brenta, G., Vaisman, M., Sgarbi, J. A., de Andrada, N. C., Bravo, P. P., Orlandi, A. M., & Graf, H. (2013)
Thyroid Physiology and Early Pregnancy
van Driel-Delprat, C. R., van Dam, E. W. C. M., & Lambalk, C. B. (2017) · Cambridge University Press eBooks · doi:10.1017/9781139976787.009
Thyroid Disease During Pregnancy: An Overview for the Primary Care Physician
Mulla, B. M., Mulla, C. M., & Hennessey, J. V. (2017) · Springer eBooks · doi:10.1007/978-3-319-39328-5_6
The Endocrine Control of Human Pregnancy
Kuo, K., Hackney, D. N., & Mesiano, S. A. (2018) · Endocrinology · doi:10.1007/978-3-319-44675-2_26
Tiroides y embarazo
Vila, L., Lucas, A., & Santiago, P. (2017) · FMC - Formación Médica Continuada en Atención Primaria · doi:10.1016/j.fmc.2016.10.002
Nutrizione iodica e ipotiroidismo neonatale
Calaciura, F., & Leonardi, D. (2018) · L Endocrinologo · doi:10.1007/s40619-018-0419-2
Thyroid dysfunction during pregnancy
Yim, C. H. (2018) · Journal of Korean Medical Association · doi:10.5124/jkma.2018.61.4.253
Вплив дифузного нетоксичного зоба на розвиток плацентарної недостатності, перебіг гестації та пологів
Payenok, O. S., Pankiv, І. V., Hrytsyshyn, B. R., & Kostiv, M. O. (2018) · INTERNATIONAL JOURNAL OF ENDOCRINOLOGY (Ukraine) · doi:10.22141/2224-0721.14.2.2018.130557
Treatment of Subclinical Hypothyroidism in the Infertile Female
Irani, M., & Pfeifer, S. M. (2018) · Springer eBooks · doi:10.1007/978-3-319-90823-6_7
Thyroid Disease in Pre- and Post-Pregnancy
Kevat, D., & Mackillop, L. H. (2019) · Springer eBooks · doi:10.1007/978-3-319-99817-6_33
Postępowanie w subklinicznej niedoczynności tarczycy u kobiet ciężarnych i dzieci
Zdrojowy-Wełna, A., Rogala, N., Zatońska, K., & Bednarek-Tupikowska, G. (2015) · Family Medicine & Primary Care Review
Schilddrüse und Schwangerschaft
Frank‐Raue, K. (2019) · Der Klinikarzt · doi:10.1055/a-1061-0678
Endocrine Metabolism IV
Bhagavan, N. V., & Ha, C. (2015) · Elsevier eBooks · doi:10.1016/b978-0-12-416687-5.00031-2
SUBCLINICAL HYPOTHYROIDISM CURRENT CONCEPTS & M ANAGEMENT STRATEGEIES
Radha Krishnan, D., Soumini, G., & Adithya, M. G. V. (2015) · Journal of Evidence Based Medicine and Healthcare · doi:10.18410/jebmh/2015/425
No Differences in Neurodevelopmental Scores of Children Born to Hypothyroid Women Treated with Levothyroxine During Preconception Versus Early Pregnancy
Lee, S. Y. (2020) · Clinical Thyroidology · doi:10.1089/ct.2020;32.464-467
Morphometric features of the fetal thyroid gland: ultrasound examination findings
Murtazina, N. I., Луцай, Е. Д., & Саренко, А. А. (2020) · Journal of Anatomy and Histopathology · doi:10.18499/2225-7357-2020-9-3-35-41
Thyroid screening in pregnancy - guideline in practice
Páleníková, P., Kalafutová, I., Horníková, Z., & Payer, J. (2017) · Vnitřní lékařství · doi:10.36290/vnl.2017.112
Comparison of ATA and Updated ACOG Guidelines for Thyroid Disease in Pregnancy. Russian translation
Pearce, E. N. (2021) · Clinical and experimental thyroidology · doi:10.14341/ket12556
The patient with thyroid disease
Chan, S. (2021) · Assisted Reproduction Techniques · doi:10.1002/9781119622215.ch13
Thyroid Disease in Pregnancy (Content last reviewed: 15th October 2018)
Jarvis, S., & Nelson‐Piercy, C. (2017)
Schilddrüse und Schwangerschaft
Frank‐Raue, K. (2021) · Geburtshilfe und Frauenheilkunde · doi:10.1055/a-1430-4514
Thyroid Disease in Pregnancy (Content last reviewed: 14th December 2020)
Jarvis, S., & Nelson‐Piercy, C. (2017)
Management Thyroid Disease in Pregnancy: Preconception, and the Postpartum Complications
man, R. F. G., & Micheal, S. (2017) · Endocrinology and Disorders · doi:10.31579/2640-1045/012
Congenital endocrine diseases & OSAHS
Service d’Endocrinologie, C. B. –. A., Drias, D., Chaouki, F., & Service de Pneumologie, E. B. –. A. (2021) · Batna Journal of Medical Sciences (BJMS) · doi:10.48087/bjmscr.2021.8216
Hypothyroidism
Shah, M., & Gharib, H. (2013) · Springer eBooks · doi:10.1007/978-1-4614-8684-8_3
Thyroid Disease During Pregnancy
Korevaar, T. I. M., & Peeters, R. P. (2022) · doi:10.1093/med/9780198870197.003.0172
Obstetric Medicine
Bernstein, L. B., Carson, M., Cruz, M., Harrison, R. K., Johnson, A., Kho, A., Lewis, B., & Tilstra, S. A. (2020) · Springer eBooks · doi:10.1007/978-3-030-50695-7_39
Hypothyroidism
Sfeir, J. G., & Gharib, H. (2022) · Springer eBooks · doi:10.1007/978-3-030-90684-9_2
Thyroid Function Classification in Early Pregnancy Varies Considerably Across Repeated Testing Within an Interval of a Few Weeks
Albashaireh, A., & Maraka, S. (2022) · Clinical Thyroidology · doi:10.1089/ct.2022;34.153-156
Thyroïde et grossesse Prise en charge diagnostique et thérapeutique de l'hypothyroïdie et l'hyperthyroïdie au cours de la grossesse
Caron, P. J. (2022) · Elsevier eBooks · doi:10.1016/b978-2-294-77583-3.00019-8
Iodine and Brain Development
Moran, V. H., & Lowe, N. M. (2016) · CRC Press eBooks · doi:10.1201/9781315372402-9
Diabetes mellitus
Nelson-Piercy, C. (2015) · CRC Press eBooks · doi:10.1201/b18316-8
6. Hypothyroidism
Jwala, S. (2016) · CRC Press eBooks · doi:10.1201/9781315200910-7
Schildklieraandoeningen
van Poelje, M. W. (2019) · Bohn Stafleu van Loghum eBooks · doi:10.1007/978-90-368-2407-1_43
Thyroid disease
Kilpatrick, S. J. (2018) · Wiley eBooks · doi:10.1002/9781119072980.ch29
Application of Selenium in Patients with Hypothyroidism during Pregnancy
曾, 超. (2020) · Advances in Clinical Medicine · doi:10.12677/acm.2020.107187
Thyroid Disorders
Buschur, E., & Thung, S. (2020) · doi:10.1002/9781119635307.ch23
Endocrine Emergencies
Tolcher, M. C., Hoff, H. S., & Aagaard, K. M. (2018) · Wiley eBooks · doi:10.1002/9781119129400.ch32
Maternal Clinical Hypothyroidism
Velasco, I., & Okosieme, O. E. (2022) · Springer eBooks · doi:10.1007/978-3-030-98777-0_6
Isolated Hypothyroxinemia During Pregnancy
López-Muñoz, E. (2022) · Springer eBooks · doi:10.1007/978-3-030-98777-0_8
Alterations of Thyroid Hormone Levels in Children with Intellectual Disability
Zhao, Z., Su, M., Wang, D., Ye, J., & Wang, X. (2022) · Neuropediatrics · doi:10.1055/a-1959-8959
Prevalence of thyroid disorders in first trimester of pregnancy
Rani, U., Paladi, R., & Anjum, M. (2022) · International Journal of Reproduction Contraception Obstetrics and Gynecology · doi:10.18203/2320-1770.ijrcog20222788
Study of trimester wise effect of hypothyroidism in pregnancy and its materno- fetal outcome
Gaikwad, V., Salvi, P., & Nandini., R. (2022) · Indian Journal of Public Health Research & Development · doi:10.37506/ijphrd.v14i4.18639
Correlation Between Maternal Subclinical hypothyroidism and Intelligence and Movement Skills of Offspring at 1 Years of AgePreprint
zhang, X., Yuan, N., Sun, J., Zhao, D., & Xu, X. (2022) · Research Square · doi:10.21203/rs.3.rs-2351951/v1
Screening for thyroid disease in pregnancy: Targeted or universal?
Ghazal, K., Moal, V., Gauchez, A., Caron, P. J., & Hamdi, S. M. (2023) · Médecine Nucléaire · doi:10.1016/j.mednuc.2023.03.001
Landmark Discoveries in Maternal–Fetal Thyroid Disease Over the Past Century
Leung, A. M. (2023) · Thyroid · doi:10.1089/thy.2022.0368
Pathologies endocriniennes
Benachi, A., Luton, D., Mandelbrot, L., & Picone, O. (2022) · Elsevier eBooks · doi:10.1016/b978-2-294-77351-8.00003-1
Screening and Management of Thyroid Dysfunction During Pregnancy
Lee, S., & Kim, S. C. (2023) · JOURNAL OF THE KOREAN SOCIETY OF MATERNAL AND CHILD HEALTH · doi:10.21896/jksmch.2023.27.3.148
Schilddrüse und Schwangerschaft
Koehler, V. F., Auernhammer, C. J., & Spitzweg, C. (2023) · Angewandte Nuklearmedizin · doi:10.1055/a-2030-6645
Schilddrüse und Schwangerschaft
Keck, C., & Diederich, S. (2023) · gynäkologie + geburtshilfe · doi:10.1007/s15013-023-5356-x
The Benefit of Levothyroxine Replacement in Maternal Subclinical and Overt Hypothyroidism on Early Child Neurodevelopment
Villela, R., & Correa, R. R. (2023) · Clinical Thyroidology · doi:10.1089/ct.2023;35.488-490
Preconceptional Management of Thyroid Disease
Rashmi, K. G., & Sahoo, J. (2023) · Springer eBooks · doi:10.1007/978-981-99-5423-0_2
Screening and Interpretation of Thyroid Function Tests in Pregnancy
Palui, R., & Kamalanathan, S. (2023) · Springer eBooks · doi:10.1007/978-981-99-5423-0_3
Thyroid Autoimmunity and Pregnancy
Sridharan, K. (2023) · Springer eBooks · doi:10.1007/978-981-99-5423-0_4
Klinik Uygulama Rehberleri Ebelik & Kadın Sağlığı
Akça, E. İ., Köroğlu, C. O., Demir, E., Alan, S., Öztürk, M., Akbaş, M., Dağlar, G., Güler, H., Özcan, H., Tokat, M. A., et al. (2022) · Akademisyen Kitabevi eBooks · doi:10.37609/akya.1139
Effects of initiation time of levothyroxine therapy in women with gestational subclinical hypothyroidism and negative thyroid peroxidase antibodies on the neurological development of offspring
Chen, J., Li, Z., Yin, F., Bao, J., Lu, Y., Yu, X., Huang, X., Xiang, H., Zhou, T., Zhu, J., et al. (2024) · Journal of Evidence-Based Medicine · doi:10.1111/jebm.12592
Endocrine Emergencies
Tolcher, M. C., Hoff, H. S., Aagaard, K. M., & Phelan, J. P. (2024) · Wiley eBooks · doi:10.1002/9781119820260.ch32
Thyroid gland
Jacobsen, L. M., Bruggeman, B., & Winter, W. E. (2024) · Elsevier eBooks · doi:10.1016/b978-0-443-14135-5.00002-8
A confusing situation in the clinic practice: Isolated maternal hypothyroxinemia
Keskin, Z. (2024) · ODÜ Tıp Dergisi · doi:10.56941/odutip.1507480
Thyroid and Parathyroid Transplantation
Sakr, M. F. (2024) · Springer eBooks · doi:10.1007/978-3-031-64102-2_18
Thyroid and Parathyroid Disease During Pregnancy
Sakr, M. F. (2024) · Springer eBooks · doi:10.1007/978-3-031-64102-2_17
Unraveling the Role of Maternal Thyroid Hormones on Fetal Development
Bernal, J. (2024) · BENTHAM SCIENCE PUBLISHERS eBooks · doi:10.2174/9789815274226124010008
Assessing the impact of a dedicated referral and management algorithm in maternal hypothyroidism
KNOTT, J. A., Bennett, M. J., & Brzozowska, M. M. (2024) · Minerva Endocrinology · doi:10.23736/s2724-6507.24.04265-9
Desvelando Secretos Hormonales
Ramos, A. F. G., Monsalve, C., Arango, J. F. B., Henao, N. A., Gómez, N. B., & López, W. (2024) · Revista de la Facultad de Ciencias Médicas de Córdoba · doi:10.31053/1853.0605.v81.n4.44304

Authors: Lazarus, J. H., Bestwick, J. P., Channon, S., Paradice, R., Maina, A., Rees, R., Chiusano, E., John, R., Guaraldo, V., George, L. M., Perona, M., Dall'Amico, D., Parkes, A. B., Joomun, M., & Wald, N. J.
Affiliations: Cardiff University (GB)
Queen Mary University of London (GB)
Ospedale Regina Margherita (IT)
University Hospital of Wales (GB)
ORCID: Lazarus, John H.
Bestwick, Jonathan P.
Channon, Sue
Joomun, Mohammed
Wald, Nicholas J.
Venue: New England Journal of Medicine
Publisher: Massachusetts Medical Society
Published: 2012-02-09
Volume: 366
Issue: 6
Pages: 493-501
ISSN: 0028-4793 (ISSN-L)
1533-4406
DOI: 10.1056/nejmoa1106104
PMC: PMC3814060
OpenAlex: W2170972205
Cited by: 635
References: 18
Citations by year: 2026: 12 · 2025: 24 · 2024: 31 · 2023: 32 · 2022: 52 · 2021: 28 · 2020: 46 · 2019: 52 · 2018: 58 · 2017: 43 · 2016: 32 · 2015: 59 · 2014: 62 · 2013: 59 · 2012: 44
FWCI: 57.49
Type: journal article
Language: en
Open access: bronze
doi.org
Locations: New England Journal of Medicine (publishedVersion)
PubMed (publishedVersion)
Europe PMC (PubMed Central) (acceptedVersion)
PubMed Central (acceptedVersion)
ORCA Online Research @Cardiff (Cardiff University) (submittedVersion)
Funders: Wellcome Trust (065143, 085966)
Topics: Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Thyroid Disorders and Treatments
Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Maternal Mental Health During Pregnancy and Postpartum
Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Thyroid Cancer Diagnosis and Treatment
Keywords: maternal hypothyroidism, levothyroxine, thyroid-stimulating hormone, free thyroxine, child neurodevelopment
MeSH terms: Child, Preschool, Female, Gestational Age, Humans, Hypothyroidism, Intelligence, Intelligence Tests, Male, Intellectual Disability, Pregnancy, Pregnancy Complications, Pregnancy Trimester, Second, Prenatal Diagnosis, Prenatal Exposure Delayed Effects, Thyroid Hormones, Thyrotropin, Thyroxine, Intention to Treat Analysis

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

Antenatal Thyroid Screening and Childhood Cognitive Function

Abstract

Overview

Integrity signals

Verification

Claims the paper makes

Claims other papers make about this one

Self-check

Citations

Cites

Cited by

Related

Metadata

Record

About these checks