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Radiofrequency Ablation as Initial Therapy in Paroxysmal Atrial Fibrillation
Open accessAbstract
BACKGROUND: There are limited data comparing radiofrequency catheter ablation with antiarrhythmic drug therapy as first-line treatment in patients with paroxysmal atrial fibrillation. METHODS: We randomly assigned 294 patients with paroxysmal atrial fibrillation and no history of antiarrhythmic drug use to an initial treatment strategy of either radiofrequency catheter ablation (146 patients) or therapy with class IC or class III antiarrhythmic agents (148 patients). Follow-up included 7-day Holter-monitor recording at 3, 6, 12, 18, and 24 months. Primary end points were the cumulative and per-visit burden of atrial fibrillation (i.e., percentage of time in atrial fibrillation on Holter-monitor recordings). Analyses were performed on an intention-to-treat basis. RESULTS: There was no significant difference between the ablation and drug-therapy groups in the cumulative burden of atrial fibrillation (90th percentile of arrhythmia burden, 13% and 19%, respectively; P=0.10) or the burden at 3, 6, 12, or 18 months. At 24 months, the burden of atrial fibrillation was significantly lower in the ablation group than in the drug-therapy group (90th percentile, 9% vs. 18%; P=0.007), and more patients in the ablation group were free from any atrial fibrillation (85% vs. 71%, P=0.004) and from symptomatic atrial fibrillation (93% vs. 84%, P=0.01). One death in the ablation group was due to a procedure-related stroke; there were three cases of cardiac tamponade in the ablation group. In the drug-therapy group, 54 patients (36%) underwent supplementary ablation. CONCLUSIONS: In comparing radiofrequency ablation with antiarrhythmic drug therapy as first-line treatment in patients with paroxysmal atrial fibrillation, we found no significant difference between the treatment groups in the cumulative burden of atrial fibrillation over a period of 2 years. (Funded by the Danish Heart Foundation and others; MANTRA-PAF ClinicalTrials.gov number, NCT00133211.).
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“Catheter ablation or combination therapy is often effective when antiarrhythmic drugs fail.226,[585][586][587]”
From 2016 ESC Guidelines for the management of atrial fibrillation developed in collaboration with EACTS (2016) · cites this paper as [585]
In the citing paper
“AF ablation, when performed in experienced centres by adequately trained teams, is more effective than antiarrhythmic drug therapy in maintaining sinus rhythm, and the complication rate, though not negligible, is similar to the complication rate for antiarrhythmic drugs.585,717,1042”
From 2016 ESC Guidelines for the management of atrial fibrillation developed in collaboration with EACTS (2016) · cites this paper as [585]
In the citing paper
“AF ablation, when performed in experienced centres by adequately trained teams, is more effective than antiarrhythmic drug therapy in maintaining sinus rhythm, and the complication rate, though not negligible, is similar to the complication rate for antiarrhythmic drugs.585,717,1042”
From 2016 ESC Guidelines for the management of atrial fibrillation developed in collaboration with EACTS (2016) · cites this paper as [585]
In the citing paper
“Complication rates were similar, but ablation was performed in expert centres, justifying catheter ablation as first-line therapy in selected patients with paroxysmal AF who ask for interventional therapy.”
From 2016 ESC Guidelines for the management of atrial fibrillation developed in collaboration with EACTS (2016) · cites this paper as [585]
In the citing paper
“As first-line treatment for paroxysmal AF, randomized trials showed only modestly improved rhythm outcome with catheter ablation compared to antiarrhythmic drug therapy.585,[721][722][723]”
From 2016 ESC Guidelines for the management of atrial fibrillation developed in collaboration with EACTS (2016) · cites this paper as [585]
In the citing paper
“Isthmus ablation is comparably safe and more effective than antiarrhythmic drug therapy, and is recommended for recurrent atrial flutter.[585][586][587]713”
From 2016 ESC Guidelines for the management of atrial fibrillation developed in collaboration with EACTS (2016) · cites this paper as [585]
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Cites
Guidelines for the management of atrial fibrillation
Authors/Task Force Members, Camm, A. J., Kirchhof, P. F., Lip, G. Y. H., Schotten, U., Savelieva, I., Ernst, S., Gelder, I. C. V., Al‐Attar, N., Hindricks, G., et al. (2010) · European Heart Journal · doi:10.1093/eurheartj/ehq278 · Cited by 5,924
Wann, L. S., Curtis, A. B., January, C. T., Ellenbogen, K. A., Lowe, J. E., Estes, N. A. M., Page, R. L., Ezekowitz, M. D., Slotwiner, D. J., Jackman, W. M., et al. (2010) · Circulation · doi:10.1161/cir.0b013e3181fa3cf4 · Cited by 1,338
Wilber, D. J., Pappone, C., Neuzil, P., De Paola, A., Marchlinski, F., Natale, A., Macle, L., Daoud, E. G., Calkins, H., Hall, B., et al. (2010) · JAMA · doi:10.1001/jama.2009.2029 · Cited by 1,170
Oakes, R. S., Badger, T. J., Kholmovski, E. G., AKOUM, N. W., Burgon, N. S., Fish, E. N., Blauer, J. J. E., Rao, S. N., DiBella, E., Segerson, N. M., et al. (2009) · Circulation · doi:10.1161/circulationaha.108.811877 · Cited by 1,123
Wazni, O. M., Marrouche, N. F., Martin, D. O., Verma, A., Bhargava, M., Saliba, W., Bash, D., Schweikert, R., Brachmann, J., Gunther, J., et al. (2005) · JAMA · doi:10.1001/jama.293.21.2634 · Cited by 1,121
Catheter Ablation Versus Antiarrhythmic Drugs for Atrial Fibrillation
Jaı̈s, P., CAUCHEMEZ, B., Macle, L., Daoud, E. G., Khairy, P., Subbiah, R. N., Hocini, M., Extramiana, F., Sacher, F., Bordachar, P., et al. (2008) · Circulation · doi:10.1161/circulationaha.108.772582 · Cited by 889
Fuster, V., Rydén, L. E., Cannom, D. S., Crijns, H. J., Curtis, A. B., Ellenbogen, K. A., Halperin, J. L., Kay, G. N., Le Huezey, J.-Y., Lowe, J. E., et al. (2011) · Circulation · doi:10.1161/cir.0b013e318214876d · Cited by 859
Calkins, H., Reynolds, M. R., Spector, P., Sondhi, M., Xu, Y., Martin, A., Williams, C. J., & Sledge, I. (2009) · Circulation Arrhythmia and Electrophysiology · doi:10.1161/circep.108.824789 · Cited by 847
Pappone, C., Augello, G., Sala, S., Gugliotta, F., Vicedomini, G., Gulletta, S., Paglino, G., Mazzone, P., Sora, N., Greiss, I., et al. (2006) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2006.08.037 · Cited by 685
Stabile, G., Bertaglia, E., Senatore, G., Simone, A. D., Zoppo, F., Donnici, G., Turco, P., Pascotto, P., FAZZARI, M., & Vitale, D. F. (2005) · European Heart Journal · doi:10.1093/eurheartj/ehi583 · Cited by 502
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Kheiri, B., Simpson, T. F., Przybylowicz, R., Merrill, M. E., Alhamoud, H., Osman, M., Dalouk, K. A., Stecker, E. C., Henrikson, C. A., & Nazer, B. (2021) · Circulation Arrhythmia and Electrophysiology · doi:10.1161/circep.120.009692 · Cited by 25
Ablation Versus Drugs: What Is the Best First-Line Therapy for Paroxysmal Atrial Fibrillation?
Santangeli, P., Biase, L. D., & Natale, A. (2014) · Circulation Arrhythmia and Electrophysiology · doi:10.1161/circep.113.000629 · Cited by 24
Diseases of the Cardiovascular System
Lockhart, P. B., & Sun, Y. (2021) · Wiley eBooks · doi:10.1002/9781119597797.ch14 · Cited by 27
Association of Atrial Fibrillation with Diabetes Mellitus, High Risk Comorbidities
Gherasim, L. (2022) · MAEDICA – a Journal of Clinical Medicine · doi:10.26574/maedica.2022.17.1.143 · Cited by 24
Method for Differentiating Left Superior Pulmonary Vein Exit Conduction from Pseudo‐Exit Conduction
Ip, J. E., Markowitz, S. M., Cheung, J. W., Liu, C. F., Thomas, G., Lessner, S., Lee, J. M., & Lerman, B. B. (2013) · Pacing and Clinical Electrophysiology · doi:10.1111/pace.12062 · Cited by 23
Landolina, M., Arena, G., Iacopino, S., Verlato, R., Pieragnoli, P., Curnis, A., Lunati, M., Rauhe, W., Senatore, G., Sciarra, L., et al. (2018) · International Journal of Cardiology · doi:10.1016/j.ijcard.2018.07.051 · Cited by 23
Charitakis, E., Metelli, S., Karlsson, L., Antoniadis, A. P., Rizas, K. D., Liuba, I., Almroth, H., Jönsson, A. H., Schwieler, J. H., Tsartsalis, D., et al. (2022) · BMC Medicine · doi:10.1186/s12916-022-02385-2 · Cited by 23
Alhede, C., Johannessen, A. C., Dixen, U., Jensen, J. S., Raatikainen, P. M. J., Hindricks, G., Walfridsson, H., Kongstad, O., Pehrson, S. M., Englund, A., et al. (2016) · EP Europace · doi:10.1093/europace/euw329 · Cited by 23
Akkaya, E., Berkowitsch, A., Zaltsberg, S., Greiß, H., Hamm, C. W., Sperzel, J., Neumann, T., & Kuniss, M. (2018) · International Journal of Cardiology · doi:10.1016/j.ijcard.2017.11.011 · Cited by 23
Voltage-guided ablation in persistent atrial fibrillation—favorable 1-year outcome and predictors
Schade, A., Costello‐Boerrigter, L. C., Steinborn, F., Bayri, A. H., Chapran, M., Surber, R., Schulze, P. C., & Mattea, V. (2020) · Journal of Interventional Cardiac Electrophysiology · doi:10.1007/s10840-020-00882-z · Cited by 23
Gao, L., & Moodie, M. (2019) · BMJ Open · doi:10.1136/bmjopen-2019-031033 · Cited by 22
Zheng, Z., Fan, J., Ji, C., Cheng, Y., Chen, X., Tang, A.-L., Feng, C., Ma, Y.-D., Hu, X., Jiang, J., et al. (2020) · American Journal of Cardiovascular Drugs · doi:10.1007/s40256-020-00435-9 · Cited by 22
He, B., Jiang, L., Hao, Z., Wang, H., & Miao, Y. (2021) · Pacing and Clinical Electrophysiology · doi:10.1111/pace.14201 · Cited by 21
Primo, J. J., Gonçalves, H., Macedo, A., Russo, P. R., Monteiro, T., Guimarães, J. P. N. Q., & Costa, O. (2017) · Revista Portuguesa de Cardiologia · doi:10.1016/j.repc.2016.11.005 · Cited by 22
Primo, J. J., Gonçalves, H., Macedo, A., Russo, P. R., Monteiro, T., Guimarães, J. P. N. Q., & Costa, O. (2017) · Revista Portuguesa de Cardiologia (English Edition) · doi:10.1016/j.repce.2016.11.013 · Cited by 22
Allan, K. S., Aves, T., Henry, S., Banfield, L. E., Victor, J. C., Dorian, P., Healey, J. S., Andrade, J. G., Carroll, S. L., & McGillion, M. H. (2020) · CJC Open · doi:10.1016/j.cjco.2020.03.013 · Cited by 22
“Our results corroborate with a previously published metaanalysis from Siontis et al.,31 who evaluated published and unpublished HRQL data from RCTs of CA performed with RFA energy vs AADs for symptomatic AF.”
MethodInfluentialJobs, A., Schwind, J., Katalinic, A., Babaev, V., Tilz, R. R., Rausch, S., Thiele, H., Eitel, I., & Eitel, C. (2018) · Clinical Research in Cardiology · doi:10.1007/s00392-018-1321-4 · Cited by 21
Unni, R. R., Prager, R. T., Odabashian, R., Zhang, J. J., Hing, N. N. F., Nery, P. B., Pi, L., Aldawood, W., Sadek, M. M., Redpath, C. J., et al. (2022) · CJC Open · doi:10.1016/j.cjco.2022.02.001 · Cited by 21
Kanagaratnam, P., McCready, J. W., Tayebjee, M. H., Shepherd, E., Sasikaran, T., TODD, D. M., Johnson, N. A., Kyriacou, A. L., Hayat, S. A., Hobson, N. A., et al. (2022) · EP Europace · doi:10.1093/europace/euac253 · Cited by 22
Riahi, S., Arbelo, E., Brugada, J., Maggioni, A. P., Tavazzi, L., Vardas, P. E., Laroche, C., Efremidis, M., Xhaët, O., Woźniak, A., et al. (2015) · EP Europace · doi:10.1093/europace/euv386 · Cited by 20
Boriani, G., Lorenzetti, S., Cerbai, E., Oreto, G., Bronzetti, G., Malavasi, V. L., Biffi, A., Padeletti, L., Botto, G., & Diemberger, I. (2017) · EP Europace · doi:10.1093/europace/eux068 · Cited by 21
Targeting the NLRP3 inflammasome signalling for the management of atrial fibrillation
Niskala, A., Heijman, J., Dobrev, D., Jespersen, T., & Saljic, A. (2024) · British Journal of Pharmacology · doi:10.1111/bph.16470 · Cited by 22
Karakasis, P., Tzeis, S. E., Pamporis, K., Schuermans, A., Theofilis, P., Milaras, N., Tsiachris, D., Efremidis, M., Antoniadis, A. P., & Fragakis, N. (2025) · EP Europace · doi:10.1093/europace/euaf110 · Cited by 26
Wazni, O. M., Dandamudi, G., Sood, N. A., HOYT, R. H., Tyler, J. D., Durrani, S., Niebauer, M. J., Makati, K. J., Halperin, B. D., Gauri, A. J., et al. (2021) · Heart Rhythm · doi:10.1016/j.hrthm.2021.10.009 · Cited by 21
Kim, J. Y., Park, H., Park, H. W., Choi, E., Park, J., Kim, J., Kang, K., Uhm, J., Joung, B., & Park, K. (2022) · Journal of the American Heart Association · doi:10.1161/jaha.122.025956 · Cited by 20
Safety of Catheter Ablation Therapy for Atrial Fibrillation in Cardiac Amyloidosis
Alhassan, H. A., Kainat, A., Donohue, J. P., Baumgartner, S. J., Akunor, H., Saba, S., Jain, S. K., & Soman, P. (2023) · Journal of the American Heart Association · doi:10.1161/jaha.122.029339 · Cited by 19
Pothineni, N. V. K., Deshmukh, A. J., Pant, S., Patel, N., Badheka, A., Chothani, A., Shah, N. N., Mehta, K. D., Savani, G. T., Singh, V., et al. (2014) · International Journal of Cardiology · doi:10.1016/j.ijcard.2014.04.250 · Cited by 20
Update on the management of atrial fibrillation
Amerena, J. V., Walters, T. E., Mirzaee, S., & Kalman, J. M. (2013) · The Medical Journal of Australia · doi:10.5694/mja13.10191 · Cited by 20
Uremic Toxins and Atrial Fibrillation: Mechanisms and Therapeutic Implications
Yamagami, F., Tajiri, K., Yumino, D., & Ieda, M. (2019) · Toxins · doi:10.3390/toxins11100597 · Cited by 20
Hermida, J. S., Chen, J., Meyer, C. G., Iacopino, S., Arena, G., Pavlović, N., Velagić, V., Healey, S., Packer, D. L., Pitschner, H.-F., et al. (2019) · American Heart Journal · doi:10.1016/j.ahj.2019.12.006 · Cited by 19
Catheter ablation of atrial fibrillation: recent advances and future challenges
Hindricks, G., & Packer, D. L. (2022) · EP Europace · doi:10.1093/europace/euac035 · Cited by 19
Catheter ablation of symptomatic atrial fibrillation: Sex, ethnicity, and socioeconomic disparities
Björkenheim, A., Fengsrud, E., & Blomström‐Lundqvist, C. (2022) · Heart Rhythm O2 · doi:10.1016/j.hroo.2022.07.008 · Cited by 17
Shi, R., Norman, M. W., Chen, Z., & Wong, T. (2018) · Future Cardiology · doi:10.2217/fca-2017-0109 · Cited by 19
El alcance protector de las acciones edilicias
Moreno, A. M. M. (1980) · Dialnet (Universidad de la Rioja) · Cited by 19
Rotors as Drivers of Atrial Fibrillation and Targets for Ablation
Schricker, A. A., Lalani, G., Krummen, D. E., & Narayan, S. M. (2014) · Current Cardiology Reports · doi:10.1007/s11886-014-0509-0 · Cited by 19
A novel four-wire-driven robotic catheter for radio-frequency ablation treatment
Yoshimitsu, K., Kato, T., Song, S.-E., & Hata, N. (2014) · International Journal of Computer Assisted Radiology and Surgery · doi:10.1007/s11548-014-0982-3 · Cited by 19
Lin, W., Chu, H., Wang, C., Chang, D., Yin, X., Wang, Y., Jiang, C., Xu, Y., Liao, Q., Yang, J., et al. (2025) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2025.09.1593 · Cited by 19
Atrial Fibrillation and Congestive Heart Failure
Thihalolipavan, S., & Morin, D. P. (2014) · Heart Failure Clinics · doi:10.1016/j.hfc.2013.12.005 · Cited by 18
Emerging pharmacotherapies for the treatment of atrial fibrillation
Capucci, A., Cipolletta, L., Guerra, F., & Giannini, I. (2018) · Expert Opinion on Emerging Drugs · doi:10.1080/14728214.2018.1446941 · Cited by 18
Rhythm versus rate control for atrial fibrillation in heart failure with preserved ejection fraction
Al‐Sadawi, M., Aleem, S., Aslam, F., Jacobs, R., Stevens, G., Almasry, I. O., Singh, A., Fan, R., & Rashba, E. J. (2022) · Heart Rhythm O2 · doi:10.1016/j.hroo.2022.06.009 · Cited by 18
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Chen, S., Yin, Y., Ling, Z., Meyer, C. G., Pürerfellner, H., Martinek, M., Kiuchi, M. G., Futyma, P., Zhu, L., Schratter, A., et al. (2022) · Journal of Clinical Medicine · doi:10.3390/jcm11226871 · Cited by 18
Ablation as First-line Therapy for Atrial Fibrillation
Andrade, J. G. (2023) · European Cardiology Review · doi:10.15420/ecr.2023.04 · Cited by 20
Aldaas, O. M., Malladi, C., Aldaas, A. M., Han, F. T., Hoffmayer, K. S., Krummen, D. E., Ho, G., Raissi, F., Birgersdotter-Green, U. M., Feld, G. K., et al. (2023) · Heart Rhythm O2 · doi:10.1016/j.hroo.2023.09.003 · Cited by 18
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Lappegård, K. T., Hovland, A., Pop, G., & Mollnes, T. E. (2013) · Scandinavian Journal of Immunology · doi:10.1111/sji.12061 · Cited by 18
Vecchio, N. (2019) · Journal of Atrial Fibrillation · doi:10.4022/jafib.2128 · Cited by 18
Demonstrating the Value of Contact Force Sensing
Calkins, H. G. (2015) · Circulation · doi:10.1161/circulationaha.115.018354 · Cited by 18
Vassilikos, V. P., Pagourelias, E. D., Laroche, C., Blomström‐Lundqvist, C., Kautzner, J., Maggioni, A. P., Tavazzi, L., Dagres, N., Brugada, J., Stuehlinger, M., et al. (2020) · EP Europace · doi:10.1093/europace/euaa236 · Cited by 19
What clinical trials of ablation for atrial fibrillation tell us – and what they do not
Amuthan, R., & Curtis, A. B. (2021) · Heart Rhythm O2 · doi:10.1016/j.hroo.2021.02.001 · Cited by 17
Blomström‐Lundqvist, C., & Wettervik, V. S. (2021) · EP Europace · doi:10.1093/europace/euab318 · Cited by 17
Li, Y., Li, Y., Sun, L., Ye, X., Cai, Q., Zhu, W., Guo, D., Ding, X., Wang, J., & Lv, X. (2022) · BMC Cardiovascular Disorders · doi:10.1186/s12872-022-02916-y · Cited by 17
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Fujii, S., Zhou, J. R., & Dhir, A. K. (2017) · Journal of Cardiothoracic and Vascular Anesthesia · doi:10.1053/j.jvca.2017.12.039 · Cited by 17
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Actualización detallada de las guías de la ESC para el manejo de la fibrilación auricular de 2012
Camm, A. J., Lip, G. Y. H., Caterina, R. D., Savelieva, I., Atar, D., Hohnloser, S. H., Hindricks, G., Kirchhof, P. F., Bax, J. J., Baumgartner, H., et al. (2012) · Revista Española de Cardiología · doi:10.1016/j.recesp.2012.11.001 · Cited by 16
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Hunter, T. D., Palli, S. R., & Rizzo, J. A. (2016) · Journal of Medical Economics · doi:10.1080/13696998.2016.1187153 · Cited by 16
Nielsen, J. B., Kragholm, K. H., Christensen, S. B., Johannessen, A. C., Torp-Pedersen, C. T., Kristiansen, S. B., Jacobsen, P. K., HANSEN, P. S., Djurhuus, M. S., Polcwiartek, C., et al. (2021) · PubMed Central · doi:10.11909/j.issn.1671-5411.2021.11.005 · Cited by 15
Elsayed, M., Abdelfattah, O., Sayed, A., Prasad, R. M., Barakat, A. F., Elgendy, I. Y., Andrade, J. G., Bunch, T. J., Thosani, A. J., Saliba, W. I., et al. (2021) · Journal of Cardiovascular Electrophysiology · doi:10.1111/jce.15308 · Cited by 15
A New Conformal Penetrating Heating Strategy for Atherosclerotic Plaque
Wang, H., Zhao, S., Zou, J., & Zhang, A. (2023) · Bioengineering · doi:10.3390/bioengineering10020162 · Cited by 15
Maury, P., Sanchis, K., Djouadi, K., Cariou, E., Delasnerie, H., Bovéda, S., Fournier, P., Itier, R., Mondoly, P., Voglimacci‐Stephanopoli, Q., et al. (2024) · PLoS ONE · doi:10.1371/journal.pone.0301753 · Cited by 15
Cheng, X., Li, X., He, Y., Liu, X., Wang, G., Cheng, L. T., & Hu, J. (2014) · Journal of Interventional Cardiac Electrophysiology · doi:10.1007/s10840-014-9945-4 · Cited by 14
Pison, L., Hocini, M., Potpara, T. S., Todd, D., Chen, J., Blomström‐Lundqvist, C., Blomström‐Lundqvist, C., Bongiorni, M. G., Pison, L., Proclemer, A., et al. (2014) · EP Europace · doi:10.1093/europace/euu277 · Cited by 15
Liu, T., Shao, Q., Korantzopoulos, P. G., Miao, S., Zhang, Z., Xu, G., Yuan, R., & Li, G. (2016) · International Journal of Cardiology · doi:10.1016/j.ijcard.2016.11.255 · Cited by 15
Moser, J., Sultan, A., Lüker, J., Servatius, H., Salzbrunn, T., Altenburg, M., Schäffer, B., Schreiber, D., Akbulak, R. Ö., Vogler, J., et al. (2017) · JACC. Clinical electrophysiology · doi:10.1016/j.jacep.2017.04.019 · Cited by 15
Surveys and Registries on Catheter Ablation of Atrial Fibrillation
Cappato, R., & Ali, H. (2021) · Circulation Arrhythmia and Electrophysiology · doi:10.1161/circep.120.008073 · Cited by 14
Antiarrhythmic drugs and strategies
Nattel, S., Gersh, B. J., & Opie, L. H. (2013) · Elsevier eBooks · doi:10.1016/b978-1-4557-3322-4.00017-x · Cited by 15
Senoo, K., Yukawa, A., Ohkura, T., Iwakoshi, H., Nishimura, T., Shimoo, S., Inoue, K., Sakatani, T., Kakita, K., Hattori, T., et al. (2023) · IJC Heart & Vasculature · doi:10.1016/j.ijcha.2023.101177 · Cited by 15
“Some studies have attempted to estimate changes in AF burden (or sinus duration) using various methods in the absence of an implantable device [26,27].”
MethodChander, S., Kumari, R., Luhana, S., Shiwlani, S., Parkash, O., Sorath, F., Wang, H. Y., Tan, S., Rahaman, Z., Mohammed, Y. N., et al. (2024) · BMC Cardiovascular Disorders · doi:10.1186/s12872-024-03983-z · Cited by 16
Vural, Ü., Balcı, A. Y., Ağlar, A. A., & Kızılay, M. (2018) · Brazilian Journal of Cardiovascular Surgery · doi:10.21470/1678-9741-2018-0130 · Cited by 14
for the AF Ablation Frontier Registry investigators, Iso, K., Nagashima, K., Arai, M., Watanabe, R., Yokoyama, K., Matsumoto, N., Otsuka, T., Suzuki, S. S., Hirata, A., et al. (2020) · Heart and Vessels · doi:10.1007/s00380-020-01721-x · Cited by 14
Acupuncture as an adjunctive therapy for arrhythmia: a Delphi expert consensus survey
Li, J., Wang, Y., Zhang, N., Su, X.-T., Lin, Y., Yang, J., Shi, G., & Liu, C. (2021) · Cardiovascular Diagnosis and Therapy · doi:10.21037/cdt-21-201 · Cited by 14
Ikemura, N., Spertus, J. A., Kimura, T., Katsumata, Y., Fujisawa, T., Ueda, I., Fukuda, K., Takatsuki, S., & Kohsaka, S. (2021) · Journal of the American Heart Association · doi:10.1161/jaha.120.019983 · Cited by 13
Arbelo, E., & Dagres, N. (2022) · EP Europace · doi:10.1093/europace/euab332 · Cited by 14
Song, Q., Tan, H., Yang, B., Liu, H., & Fan, C. (2024) · Reviews in Cardiovascular Medicine · doi:10.31083/j.rcm2502071 · Cited by 13
Improvement of Phased Antenna Array Applied in Focused Microwave Breast Hyperthermia
Wang, X., Xi, Z., Ye, K., Gong, Z., Chen, Y., & Wang, X. (2024) · Sensors · doi:10.3390/s24092682 · Cited by 13
“The current clinically applicable mechanism of microwave hyperthermia is to insert a thin metallic probe into the human breast and directly transfer microwave energy to the tumor, which is an invasive treatment method [12–14].”
BackgroundMethodPavlović, N., Chierchia, G., Velagić, V., Hermida, J. S., Healey, S., Arena, G., Badenco, N., Meyer, C. G., Chen, J., Iacopino, S., et al. (2021) · American Heart Journal · doi:10.1016/j.ahj.2021.08.007 · Cited by 15
Atrial Fibrillation Ablation: Indications, Emerging Techniques, and Follow-Up
Gerstenfeld, E. P., & Duggirala, S. (2015) · Progress in Cardiovascular Diseases · doi:10.1016/j.pcad.2015.07.008 · Cited by 13
Mechanisms Underlying AF: Triggers, Rotors, Other?
Krummen, D. E., Hebsur, S., Salcedo, J., Narayan, S. M., Lalani, G., & Schricker, A. A. (2015) · Current Treatment Options in Cardiovascular Medicine · doi:10.1007/s11936-015-0371-4 · Cited by 13
Zheng, Y.-R., Chen, Z., Ye, L., & Wang, L. (2015) · Europe PMC (PubMed Central) · doi:10.11909/j.issn.1671-5411.2015.05.012 · Cited by 13
Atrial Fibrillation: Beyond Rate Control
Bhatia, S., Sugrue, A. M., & Asirvatham, S. J. (2018) · Mayo Clinic Proceedings · doi:10.1016/j.mayocp.2017.10.024 · Cited by 13
Radiofrequency Ablation as Initial Therapy in Paroxysmal Atrial Fibrillation
Mehra, R., & Benjamin, E. J. (2013) · New England Journal of Medicine · doi:10.1056/nejmc1214193 · Cited by 13
Uhm, J., Won, H., Joung, B., Nam, G., Choi, K., Lee, M., Kim, Y.-H., & Pak, H. (2014) · Yonsei Medical Journal · doi:10.3349/ymj.2014.55.5.1238 · Cited by 12
Habibi, M., & Calkins, H. G. (2019) · Herzschrittmachertherapie + Elektrophysiologie · doi:10.1007/s00399-019-00651-0 · Cited by 12
Kistler, P. M., Sanders, P., Amarena, J., Bain, C., Chia, K. K. M., Choo, W. K., Eslick, A., Hall, T. L., Hopper, I., Kotschet, E., et al. (2024) · Heart Lung and Circulation · doi:10.1016/j.hlc.2023.12.024 · Cited by 12
Mechanistic Insights From Trials of Atrial Fibrillation Ablation: Charting a Course for the Future
Goldberger, J. J., Mitrani, R. D., Zaatari, G., & Narayan, S. M. (2024) · Circulation Arrhythmia and Electrophysiology · doi:10.1161/circep.124.012939 · Cited by 12
Zörner, C. R., Tønnesen, J., Riis‐Vestergaard, L. D., Middelfart, C., Hein, R., Rasmussen, P. V., Ruwald, M. H., Gislason, G., & Hansen, M. L. (2024) · EP Europace · doi:10.1093/europace/euae231 · Cited by 12
Pulsed Field Ablation of Atrial Fibrillation: A Novel Technology for Safer and Faster Ablation
Carta‐Bergaz, A., Ríos-Muñoz, G. R., Ávila, P., Atienza, F., González-Torrecilla, E., & Arenal, Á. (2024) · Biomedicines · doi:10.3390/biomedicines12102232 · Cited by 12
Ablation of atrial fibrillation
Wright, M. J., & Narayan, S. M. (2014) · Trends in Cardiovascular Medicine · doi:10.1016/j.tcm.2014.11.009 · Cited by 12
Lim, P. C. Y., Toh, J. J. H., Loh, J. K., Lee, E. C. Y., Chong, D., Tan, B. Y., Ho, K. L., Ching, C. K., & Teo, W. S. (2016) · Journal of Arrhythmia · doi:10.1016/j.joa.2016.08.007 · Cited by 12
Atrial fibrillation ablation alone or atrial fibrillation ablation plus an antiarrhythmic drug?
Pokorney, S. D., & Daubert, J. P. (2018) · European Heart Journal · doi:10.1093/eurheartj/ehy120 · Cited by 12
Lee, E., Lee, S., Choi, E., Han, K., Cha, M., Lip, G. Y. H., & Oh, S. (2020) · Journal of Cardiovascular Electrophysiology · doi:10.1111/jce.14737 · Cited by 12
Wakamatsu, Y., Nagashima, K., Watanabe, R., Arai, M., Yokoyama, K., Matsumoto, N., Otsuka, T., Suzuki, S. S., Hirata, A., Murakami, M., et al. (2020) · International Heart Journal · doi:10.1536/ihj.20-335 · Cited by 12
Deshpande, R., Al‐Khadra, Y., SINGANALLUR, P. M., Botchway, A., & Labedi, M. R. (2022) · Journal of Interventional Cardiac Electrophysiology · doi:10.1007/s10840-022-01365-z · Cited by 13
Efremidis, M., Letsas, Κ. P., Georgopoulos, S., Karamichalakis, N., Vlachos, K. G., Lioni, L., Bazoukis, G., Saplaouras, A., Sakellaropoulou, A., Kolokathis, A., et al. (2018) · Acta cardiologica. Supplementum · doi:10.1080/00015385.2018.1494114 · Cited by 12
Lakkireddy, D. (2020) · Journal of Atrial Fibrillation · doi:10.4022/jafib.2266 · Cited by 12
Bose, A., Chevli, P. A., Berberian, G., Januszkiewicz, J., Ahmad, G., Hashmath, Z., Mishra, A. K., & Laidlaw, D. W. (2020) · Journal of Interventional Cardiac Electrophysiology · doi:10.1007/s10840-020-00916-6 · Cited by 12
Moltrasio, M., Iacopino, S., Arena, G., Pieragnoli, P., Molon, G., Manfrin, M., Verlato, R., Ottaviano, L., Rovaris, G., Catanzariti, D., et al. (2021) · Journal of Cardiovascular Medicine · doi:10.2459/jcm.0000000000001176 · Cited by 12
Farwati, M., Wazni, O. M., Tarakji, K. G., Diab, M., Scandinaro, A. L., Amin, M., Zmaili, M. A., Bazarbashi, N., Dikilitas, O., Nakagawa, H., et al. (2021) · Circulation Arrhythmia and Electrophysiology · doi:10.1161/circep.121.009938 · Cited by 12
Zeemering, S., Borof, K., Schotten, U., Obergassel, J., Camm, A. J., Crijns, H. J. G. M., Eckardt, L., Fabritz, L., Goette, A., Habibi, Z., et al. (2025) · EClinicalMedicine · doi:10.1016/j.eclinm.2025.103457 · Cited by 13
O’Neill, M. J., Yoneda, Z. T., Crawford, D. M., Ye, F., Ao, M., Pitchford, L. M., Rathmacher, J. A., Murray, K. T., Akers, W. S., Roden, D. M., et al. (2021) · Trials · doi:10.1186/s13063-021-05553-6 · Cited by 11
Effect of catheter ablation on the hemodynamics of the left atrium
Vogl, B. J., Shaer, A. E., van Zyl, M., Killu, A. M., Alkhouli, M. A., & Hatoum, H. (2022) · Journal of Interventional Cardiac Electrophysiology · doi:10.1007/s10840-022-01191-3 · Cited by 11
Metadata
- Authors
- Cosedis Nielsen, J., Johannessen, A., Raatikainen, P., Hindricks, G., Walfridsson, H., Kongstad, O., Pehrson, S., Englund, A., Hartikainen, J., Mortensen, L. S., & Hansen, P. S.
- Affiliations
- Gentofte Hospital (DK)
- Tampere University Hospital (FI)
- University Hospital Leipzig (DE)
- Linköping University Hospital (SE)
- Skåne University Hospital (SE)
- Rigshospitalet (DK)
- Örebro University Hospital (SE)
- Kuopio University Hospital (FI)
- Aarhus University Hospital (DK)
- ORCID
- Venue
- New England Journal of Medicine
- Publisher
- Massachusetts Medical Society
- Published
- 2012-10-25
- Volume
- 367
- Issue
- 17
- Pages
- 1587-1595
- ISSN
- 0028-4793 (ISSN-L)
- 1533-4406
- OpenAlex
- W2164489173
- Cited by
- 720
- References
- 26
- Citations by year
- 2026: 18 · 2025: 42 · 2024: 60 · 2023: 33 · 2022: 73 · 2021: 79 · 2020: 58 · 2019: 39 · 2018: 38 · 2017: 50 · 2016: 53 · 2015: 44 · 2014: 68 · 2013: 54 · 2012: 8
- FWCI
- 35.82
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- New England Journal of Medicine (publishedVersion)
- PubMed (publishedVersion)
- Lund University Publications (Lund University) (submittedVersion, other-oa)
- Funders
- Sanofi
- Hjerteforeningen (05-4-B284-A466-22237)
- Foundation for Cardiovascular Research
- Sydäntutkimussäätiö
- St. Jude Medical
- Biosense Webster
- Topics
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Atrial Fibrillation Management and Outcomes
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiac Arrhythmias and Treatments
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiac pacing and defibrillation studies
- Keywords
- paroxysmal atrial fibrillation, radiofrequency catheter ablation, antiarrhythmic drugs, class Ic antiarrhythmic drugs, class III antiarrhythmic agents, first-line therapy, arrhythmia burden, symptomatic atrial fibrillation, cardiac tamponade
- MeSH terms
- Aged, Anti-Arrhythmia Agents, Atrial Fibrillation, Atrial Flutter, Female, Flecainide, Follow-Up Studies, Humans, Male, Middle Aged, Propafenone, Quality of Life, Electrocardiography, Ambulatory, Treatment Outcome, Catheter Ablation, Cost of Illness, Statistics, Nonparametric, Intention to Treat Analysis
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