The DOI matches its Crossref record; 43 of the 43 references it cites were found in a registry or an index.
Brain Swelling and Death in Children with Cerebral Malaria
Open accessAbstract
BACKGROUND: Case fatality rates among African children with cerebral malaria remain in the range of 15 to 25%. The key pathogenetic processes and causes of death are unknown, but a combination of clinical observations and pathological findings suggests that increased brain volume leading to raised intracranial pressure may play a role. Magnetic resonance imaging (MRI) became available in Malawi in 2009, and we used it to investigate the role of brain swelling in the pathogenesis of fatal cerebral malaria in African children. METHODS: We enrolled children who met a stringent definition of cerebral malaria (one that included the presence of retinopathy), characterized them in detail clinically, and obtained MRI scans on admission and daily thereafter while coma persisted. RESULTS: Of 348 children admitted with cerebral malaria (as defined by the World Health Organization), 168 met the inclusion criteria, underwent all investigations, and were included in the analysis. A total of 25 children (15%) died, 21 of whom (84%) had evidence of severe brain swelling on MRI at admission. In contrast, evidence of severe brain swelling was seen on MRI in 39 of 143 survivors (27%). Serial MRI scans showed evidence of decreasing brain volume in the survivors who had had brain swelling initially. CONCLUSIONS: Increased brain volume was seen in children who died from cerebral malaria but was uncommon in those who did not die from the disease, a finding that suggests that raised intracranial pressure may contribute to a fatal outcome. The natural history indicates that increased intracranial pressure is transient in survivors. (Funded by the National Institutes of Health and Wellcome Trust U.K.).
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
In the citing paper
“Similar to LCMV meningitis, death from cerebral malaria results from the accumulation of water in the cranium and brainstem herniation (156, 157).”
From The anatomy and immunology of vasculature in the central nervous system (2019) · cites this paper as [156]
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Manual for the identification of medical bacteria.
Cowan, S. T., & Steel, K. (1965) · Cambridge University Press eBooks · Cited by 4,823
Cowan and Steel's Manual for the Identification of Medical Bacteria
Cowan, S. T., Feltham, R. K. A., Steel, K., & Barrow, G. I. (1993) · Cambridge University Press eBooks · doi:10.1017/cbo9780511527104 · Cited by 3,244
World Health Organization (2000) · Transactions of the Royal Society of Tropical Medicine and Hygiene · doi:10.1016/s0035-9203(00)90300-6 · Cited by 1,110
Artesunate versus quinine for treatment of severe falciparum malaria: a randomised trial.
(2005) · The Lancet · doi:10.1016/s0140-6736(05)67176-0 · Cited by 1,050
Dondorp, A. M., Fanello, C. A., Hendriksen, I. C. E., Gomes, E., Seni, A., Chhaganlal, K. D., Bojang, K., Olaosebikan, R., Anunobi, N., Maitland, K., et al. (2010) · The Lancet · doi:10.1016/s0140-6736(10)61924-1 · Cited by 1,015
Severe falciparum malaria. World Health Organization, Communicable Diseases Cluster.
(2000) · PubMed · Cited by 920
MacPherson, G. G., Warrell, M. J., White, N. J., Looareesuwan, S., & Warrell, D. A. (1985) · PubMed Central · Cited by 825
Differentiating the pathologies of cerebral malaria by postmortem parasite counts
Taylor, T. E., Fu, W. J., Carr, R., Whitten, R. O., Mueller, J. G., Fosiko, N. G., Lewallen, S., Liomba, N. G., & Molyneux, M. E. (2004) · Nature Medicine · doi:10.1038/nm986 · Cited by 710
Self-citationThe Neuropathology of Fatal Cerebral Malaria in Malawian Children
Dorovini‐Zis, K., Schmidt, K. L., Huynh, H., Fu, W., Whitten, R. O., Milner, D. A., Kamiza, S., Molyneux, M. E., & Taylor, T. E. (2011) · American Journal Of Pathology · doi:10.1016/j.ajpath.2011.01.016 · Cited by 304
Self-citationThe Relationship between Age and the Manifestations of and Mortality Associated with Severe Malaria
Dondorp, A. M., Lee, S. J., Faiz, M. A., Mishra, S. K., Price, R. N., Tjitra, E., Than, M., Htut, Y., Mohanty, S., Yunus, E. B., et al. (2008) · Clinical Infectious Diseases · doi:10.1086/589287 · Cited by 293
Flagged first, then by citations
Research works printed but not linked: 5
- MacPherson GG, 1985, Am J Pathol, 119, 385
- Turner GD, 1998, Am J Pathol, 152, 1477
- Clark IA, 1993, Q J Med, 86, 217
- Romano A, 2003, Radiol Med, 106, 521
- Meder JF, 1994, J Neuroradiol, 21, 118
Cited by
Sorted by citations
Items 301–400 of 402
Why it might be bad for brain cells to eat malaria parasites
Higgins, M. K. (2021) · The Journal of Experimental Medicine · doi:10.1084/jem.20202664 · Cited by 2
Ansong, D., Seydel, K. B., & Taylor, T. E. (2020) · Elsevier eBooks · doi:10.1016/b978-0-323-55512-8.00101-0 · Cited by 3
Self-citationIs there a role for bradykinin in cerebral malaria pathogenesis?
Pinheiro, A. S., Kazura, J. W., Pinheiro, A. A. S., & Schmaier, A. H. (2023) · Frontiers in Cellular and Infection Microbiology · doi:10.3389/fcimb.2023.1184896 · Cited by 3
Jin, Z., Pang, W., Zhao, Y., Min, H., Yao, S., Bian, Z., Wen, Y., Peng, C., Cao, Y., & Zheng, L. (2024) · International Journal for Parasitology Drugs and Drug Resistance · doi:10.1016/j.ijpddr.2024.100539 · Cited by 2
O'Brien, N. F., Raees, M. Q., Wynkoop, H. J., Yu, M., Small, D. S., Seydel, K. B., Gushu, M. B., Phiri, T., June, S., & Taylor, T. E. (2025) · Neurocritical Care · doi:10.1007/s12028-025-02245-w · Cited by 2
Self-citationETS-guided iPSC-endothelial models recapitulate malaria pathogenesis
Korbmacher, F., Long, R. K. M., Fleckenstein, H., Poliński, P., Crusius, D., Piatti, L., López-Gutiérrez, B., Batzilla, A., Trivedi, V., Ebisuya, M., et al. (2026) · EMBO Molecular Medicine · doi:10.1038/s44321-026-00467-9 · Cited by 2
Diagnostik und Therapie neurologischer Reiseerkrankungen
Maschke, M. (2020) · DNP - Der Neurologe und Psychiater · doi:10.1007/s15202-020-2850-z · Cited by 2
An Overview of Cerebral Malaria: Lessons Learnt from Observations in Humans and Experimental Models
Kar, S. K. (2021) · Biomedical Journal of Scientific & Technical Research · doi:10.26717/bjstr.2021.35.005639 · Cited by 2
Wilson, K. J., Tu, Z., Mbale, E. W., Mhango, P. P., Kayange, P., Gladstone, M., Harding, S. P., Gottlob, I., García‐Fiñana, M., Shen, Y., et al. (2023) · Wellcome Open Research · doi:10.12688/wellcomeopenres.19166.1 · Cited by 2
Self-citationMalaria tropica und Dengue-Fieber – eine Herausforderung der Intensivmedizin
Eder, B. V. A., Bissinger, A., Rießen, R., & Haap, M. M. (2018) · Intensivmedizin up2date · doi:10.1055/s-0043-122729 · Cited by 2
Silesky-Jiménez, J. I., & Hidalgo, J. (2021) · Springer eBooks · doi:10.1007/978-3-030-70034-8_31 · Cited by 2
Brooks, H. M. (2017) · ERA: Education and Research Archive (University of Alberta) · doi:10.7939/r3jd4q33z · Cited by 2
John, C. C. (2020) · Clinical Infectious Diseases · doi:10.1093/cid/ciaa1659 · Cited by 2
Okuta, C. A. (2021) · Cited by 2
Laurens, M. B., & Plowe, C. V. (2023) · Encyclopedia of sustainability science and technology series · doi:10.1007/978-1-0716-2463-0_536 · Cited by 2
Raees, M. Q., Chimalizeni, Y. F., Liomba, A. W. M., Pensulo, P., Gushu, M. B., Tebulo, A., Malenga, A., Sikorski, M. J., Holloway, A., Bhutta, A. T., et al. (2023) · American Journal of Tropical Medicine and Hygiene · doi:10.4269/ajtmh.22-0445 · Cited by 1
Self-citationChintsanya, M., Talham, C. J., Zhang, B., Taylor, T. E., & Seydel, K. B. (2024) · Malawi Medical Journal · doi:10.4314/mmj.v36i2.10 · Cited by 1
Self-citationStins, M. F., Gramaglia, I., Velez, J., Pardo, C. A., & van der Heyde, H. (2025) · Cells · doi:10.3390/cells14110807 · Cited by 1
O'Brien, N. F., Tshimanga, T., Mangwangu, F. Y., Mayindombe, L., Ekandji, R. T., Mbaka, J. P., Phiri, T., June, S., Gushu, M. B., Wynkoop, H. J., et al. (2025) · The Ultrasound Journal · doi:10.1186/s13089-025-00430-8 · Cited by 1
Matsuo-Dapaah, J., Alshaweesh, J., Lee, M. S. J., Hayashi, T., Dash, R., Kuroda, M., Tainaka, K., Ozawa, M., Kuratani, A., Yamamoto, M., et al. (2025) · mBio · doi:10.1128/mbio.01249-25 · Cited by 3
Garcia-Muñoz, A. C., Marfouk, O., Michel, C. P., Varlet, I., Royer, E., Perles‐Barbacaru, T., & Viola, A. (2025) · PLoS ONE · doi:10.1371/journal.pone.0328693 · Cited by 1
Dorovini‐Zis, K., Li, H., Chen, Z., Zhang, B., Small, D. S., & Taylor, T. E. (2025) · Journal of Neuropathology & Experimental Neurology · doi:10.1093/jnen/nlaf104 · Cited by 1
Self-citationKassegne, K., Shen, H., Chen, S., Xu, S., Li, J., Xu, B., Deitsch, K., Wang, Y., Zhou, X.-N., & Chen, J. (2025) · EBioMedicine · doi:10.1016/j.ebiom.2025.106041 · Cited by 1
Thelwell, J., & Johnson, A. J. (2026) · Neuroglia · doi:10.3390/neuroglia7030018 · Cited by 1
Raees, M. Q., Gushu, M. B., Taylor, T. E., Seydel, K. B., Wynkoop, H. J., & O'Brien, N. F. (2024) · Frontiers in Pediatrics · doi:10.3389/fped.2024.1295254 · Cited by 1
Self-citationLongitudinal associations of plasma amino acid levels with recovery from malarial coma
Granger, D. L., Ansong, D., Agbenyega, T., Liddle, M. S., Brinton, B. A., Hale, D. C., Lopansri, B. K., Reithinger, R., & Bisanzio, D. (2024) · Malaria Journal · doi:10.1186/s12936-024-05077-9 · Cited by 1
Sherman, M. G., Dwivedi, P., Olowojesiku, R., Imam, R., Chastang, K. M., Trujillo-Rivera, E. A., Bost, J. E., Mukadam, A. M., O'Brien, N. F., Moxon, C. A., et al. (2025) · American Journal of Tropical Medicine and Hygiene · doi:10.4269/ajtmh.24-0700 · Cited by 1
Self-citationTeaching and Practicing Neuro-Ophthalmology in Low-Resource Countries
Katz, B. J., Farris, B. K., Golnik, K. C., Lawlor, M., & Postels, D. G. (2016) · Journal of Neuro-Ophthalmology · doi:10.1097/wno.0000000000000420 · Cited by 1
Neurosonology in Tropical Medicine
Clark, D., & Hutchinson, P. J. A. (2020) · Springer eBooks · doi:10.1007/978-3-030-48202-2_20 · Cited by 1
Rocha, V. L., Vaz, J. B., da Silva, J. G., Oliveira, T. R. J., & Gonçalves, I. M. (2022) · Research Society and Development · doi:10.33448/rsd-v11i5.28334 · Cited by 1
Dietemann, J.-L., Eid, M. A., Koob, M., Kremer, S., Soares, I. M., & Bernardo, R. (2018) · Elsevier eBooks · doi:10.1016/b978-2-294-75394-7.00015-1 · Cited by 1
Innate immune responses to Plasmodium falciparum disrupt the blood-brain barrierPreprint
Batzilla, A., Dernick, P., Bezney, J., Gschwind, A. R., Nakaki, F., Altadill, M., Fleckenstein, H., Piatti, L., Sanz, S., Fiegl, M., et al. (2025) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2025.10.20.683440 · Cited by 1
MRI Neuroimaging in Pediatric Cerebral Malaria
Kampondeni, S. D., & Potchen, M. J. (2015) · Springer eBooks · doi:10.1007/978-1-4614-8326-7_84
Self-citationFlux balance analysis of Plasmodium falciparum growth and energy metabolism
Burger, R. W. (2017) · SUNScholar (Stellenbosch University)
Cerebral Malaria: Players in the Pathogenic Mechanism and Treatment Strategies
Dwivedi‐Agnihotri, H., & Tripathi, R. (2018) · Springer eBooks · doi:10.1007/978-981-13-1577-0_3
Granulomatous Diseases of the Central Nervous System
Wang, M., & Ding, Z. (2019) · Springer eBooks · doi:10.1007/978-981-13-6904-9_16
Malaria: a moderate to fatal disease
Kumar, S. (2018) · Journal of Emerging Technologies and Innovative Research
Malaria: pathology, immune response, and vaccine design: A mini review
Pan, H. S., & Tucker, H. O. (2020) · Neurology and Neuroscience · doi:10.33425/2692-7918.1001
Cerebral Malaria and Toxoplasmosis: Could their Concomitant Presentation Worsen Psychotic Condition?
Ibrahim, M. A., Atilola, O., Mohammed, A., Awosanya, E., Odetokun, I. A., Muhammad, A. I., Chukwudi, C. U., Ukwaja, K. N., & Oyeyemi, O. T. (2020) · Annals of Science and Technology · doi:10.2478/ast-2020-0011
Severe stridor and profound weakness after cerebral malaria
Fuller, C. J., Wooldridge, G., Liomba, A., & Ray, S. (2021) · BMJ Case Reports · doi:10.1136/bcr-2020-237681
Leveling the Playing Field: Combining Pediatric Neurology and Global Health
Postels, D. G. (2021) · Pediatric Neurology · doi:10.1016/j.pediatrneurol.2021.04.012
Laurens, M. B., & Plowe, C. V. (2022) · Springer eBooks · doi:10.1007/978-1-4939-2493-6_536-3
Tropical Infections of the CNS: A worldwide problem
Acosta, M. T., Saini, A. G., Postels, D. G., Medina, M. T., Cerisola, A., & SINGHI, P. D. (2021) · Journal of the International Child Neurology Association · doi:10.17724/jicna.2021.224
Storm, J., Wu, Y., Davies, J. D., Moxon, C. A., & Craig, A. G. (2020) · Wellcome Open Research · doi:10.12688/wellcomeopenres.15602.2
Kaushansky, A. (2019) · Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature · doi:10.3410/f.735848622.793561854
Miscellaneous Parasitic Infections
(2016) · Elsevier eBooks · doi:10.1016/b978-0-323-44592-4.50126-8
Cerebral malaria is regulated by host mediated changes in Plasmodium gene expressionPreprint
Cimperman, C. K., Peña, M., Gokcek, S. M., Theall, B. P., Patel, M. V., Sharma, A., Qi, C., Sturdevant, D. E., Miller, L. H., Collins, P. L., et al. (2022) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2022.11.23.517617
Retinal Imaging Technologies in Cerebral Malaria: A Systematic ReviewPreprint
Wilson, K. J., Dhalla, A., Meng, Y., Tu, Z., Zheng, Y., Mhango, P. P., Seydel, K. B., & Beare, N. A. V. (2022) · Research Square · doi:10.21203/rs.3.rs-2380577/v1
Self-citationFATORES DE RISCOS ASSOCIADOS A INFECÇÕES POR PARASITOSES INTESTINAIS EM CRIANÇAS
Filho, P. S. D. P. S., de Azevêdo, R. A., Barbosa, S. L. M., Batista, M. E. N. S., do Nascimento, B. P., da Silva, A. A., Portela, M. H. D. R. B., Nunes, J. K. O., de Abreu, J. E., & Fontenele, F. M. (2023) · Paulo Sérgio da Paz Silva Filho eBooks · doi:10.56161/sci.ed.20230305c8
MALÁRIA CEREBRAL: A IMPORTÂNCIA DO DIAGNÓSTICO PRECOCE COMO FATOR PARA O TRATAMENTO ASSERTIVO
Filho, P. S. D. P. S., Nunes, L. D. S., Santana, A. L. C., & Fé, J. A. D. M. M. (2023) · Paulo Sérgio da Paz Silva Filho eBooks · doi:10.56161/sci.ed.20230305c7
Sousa, D. G. D. S. (2023) · Paulo Sérgio da Paz Silva Filho eBooks · doi:10.56161/sci.ed.20230305c6
OLIVEIRA, J. C., LOPES, F. D. C. D., Soares, L. O. L., & Barros, V. C. (2023) · Paulo Sérgio da Paz Silva Filho eBooks · doi:10.56161/sci.ed.20230305c2
CONDIÇÕES AMBIENTAIS E DE SAÚDE DOS POVOS INDÍGENAS ASSOCIADA AS DOENÇAS PARASITÁRIAS
Alves, M. G. F., Guilhermino, A. V., Barreto, M. E. L., Ribeiro, M. D. S., Silva, E. N., Sousa, K. M., Pinheiro, G. F. A., Carvalho, D. S., Mendonça, M. D. B., & Rebouças, D. M. (2023) · Paulo Sérgio da Paz Silva Filho eBooks · doi:10.56161/sci.ed.20230305c1
Mata, A. C. V., Guimarães, I. P. D. S., Lopes, A. D. T., Costa, E. B., Neto, A. G. A., Silva, C. E., do Nascimento, B. P., Rodrigues, L. G., dos Anjos, N. B., & Câmara, F. D. M. M. (2023) · Paulo Sérgio da Paz Silva Filho eBooks · doi:10.56161/sci.ed.20230305c3
LEISHMANIOSE TEGUMENTAR AMERICANA: PARÂMETROS CLÍNICOS, DIAGNÓSTICO E TRATAMENTO
Mota, L. P., Santana, A. L. C., dos Anjos, N. B., Leal, R. M. D. S., & Fé, J. A. D. M. M. (2023) · Paulo Sérgio da Paz Silva Filho eBooks · doi:10.56161/sci.ed.20230305c4
Corpus Callosum Hematoma Revealing Imported Neuromalarial Disease: A Case Report
Khahouri, E., Tougar, S., Maghrabi, O., Mashrouh, W., Mabchour, M., Mabchour, M., & Charra, B. (2023) · Medical Research Archives · doi:10.18103/mra.v11i6.3899
Woodford, J., Gillman, A., Jenvey, P., Roberts, J., Woolley, S., Barber, B. E., Fernandez, M., Rose, S., Thomas, P. A., Anstey, N. M., et al. (2023) · doi:10.1201/9781003298038-36
Touré, A. F., Camara, A. Y., Bangoura, A., Camara, M. L., Soumah, M. M., & Nabe, S. (2023) · Open Journal of Emergency Medicine · doi:10.4236/ojem.2023.114016
Ray, S., Fuller, C. E., Boubour, A., Tshimangani, T., Kafoteka, E., Liomba, A. M., Malenga, A., Tebulo, A., Pensulo, P., Gushu, M. B., et al. (2024) · SSRN Electronic Journal · doi:10.2139/ssrn.4771360
Self-citationRay, S., Fuller, C. E., Ahmadu, A., Kafoteka, E., Liomba, A. M., Malenga, A., Tebulo, A., Pensulo, P., Gushu, M. B., Chilingulo, C., et al. (2024) · SSRN Electronic Journal · doi:10.2139/ssrn.4771349
Self-citationCurrent adjunctive therapy for the treatment of severe and cerebral malaria
Islahi, S., Imam, M., Siddiqui, F. A., & Qidwai, T. (2024) · Elsevier eBooks · doi:10.1016/b978-0-323-95328-3.00006-4
Murine model captures evolution of edema in experimental cerebral malaria
Taylor, T. E. (2024) · Trends in Parasitology · doi:10.1016/j.pt.2024.05.008 · Cited by 1
Self-citationChaudhary, M., & Vijay Kumar, S. S. (2024) · Disaster and Emergency Medicine Journal · doi:10.5603/demj.100606
Cerebral Malaria and Its Neuroinflammatory, Cognitive, and Neuropsychiatric Associations
Boivin, M. J., & Stiles, J. K. (2024) · doi:10.1093/oso/9780192870414.003.0014
Variability of day-to-day pulsatility index change in children with cerebral malaria
Jordan, J., O'Brien, N. F., Li, P., Musungufu, D. A., Ekandji, R. T., Mbaka, J. P., Mayindombe, L., Giresse, B., Phiri, T., June, S., et al. (2024) · Frontiers in Neurology · doi:10.3389/fneur.2024.1466941
Petronilho, F. C., Giustina, A. D., & Danielski, L. G. (2024) · Elsevier eBooks · doi:10.1016/b978-0-443-19130-5.00004-6
McDonnell, S., MacCormick, I. J. C., Harkin, K., Medina, R. J., Rodríguez, A., & Stitt, A. W. (2025) · Current Eye Research · doi:10.1080/02713683.2025.2463142
Neuroimaging of Mosquito-Borne Tropical Diseases
Meneses, M., Guarilha, T., Teixeira, S. R., & Vidal, L. (2025) · Infectious diseases · doi:10.5772/intechopen.1008304
Blood-Based Neurologic Biomarkers in Pediatric Cerebral MalariaPreprint
Raees, M. Q., Soko, M., Vidal, L., Chetcuti, K., Goyal, M. S., Mondal, A., Tomlinson, A. Z., Topjian, A., Nadkarni, V., Brien, N. O. A., et al. (2025) · SSRN Electronic Journal · doi:10.2139/ssrn.5174016
Self-citationOlivero, R. M., & Barnett, E. D. (2025) · Elsevier eBooks · doi:10.1016/b978-0-323-82763-8.00236-3
Role of mast cell-derived exosomes in exacerbating neuronal injury of experimental cerebral malaria
Wang, Q., Mo, X., Li, H., Ye, M., Fei, G., Chen, P., Wang, Y., Hou, X., He, J., Liu, W., et al. (2025) · Parasites & Vectors · doi:10.1186/s13071-025-06863-3
A Prospective Study of Magnetic Resonance Imaging of Brain in Cerebral Malaria in Children
Patel, S., Mishra, P., & Majhi, M. (2023) · Research and reviews in pediatrics. · doi:10.4103/rrp.rrp_21_23
Mini-review and situation report on the role and usefulness of nuclear medicine imaging for malaria
Duvenhage, J., Zeevaart, J. R., Sathekge, M. M., & Ebenhan, T. (2025) · European Journal of Nuclear Medicine and Molecular Imaging · doi:10.1007/s00259-025-07443-4
Specificity and kinetics of human candidate cerebral malaria biomarkers in mice
Gomes, C., Chicas, L., Crotty, K. A., Salzano, I., Tawfiles, D., & Rodrı́guez, A. (2025) · Frontiers in Malaria · doi:10.3389/fmala.2025.1553466
Hu, R., Shin, Y. J., Joof, F., Howard, C. C., Smith, J. D., & Zheng, Y. Y. (2025) · STAR Protocols · doi:10.1016/j.xpro.2025.104160
Cause-specific mortality in a cohort of paediatric cerebral malaria patients
Wynkoop, H. J., Bvalani-Kaunda, R., Seydel, K. B., Moxon, C. A., Chimalizeni, Y. F., Taylor, T. E., Birbeck, G. L., Postels, D. G., & O'Brien, N. F. (2025) · Malaria Journal · doi:10.1186/s12936-025-05619-9
Self-citationBinila Chacko, I., Platt, S. E. C., Tong, S. Y. C., Hai, D. H. T., & Vijayaraghavan, B. K. T. (2025) · Elsevier eBooks · doi:10.1016/b978-0-443-11611-7.00021-9
Karikari, A. A., Wruck, W., & Adjaye, J. (2021) · Figshare · doi:10.6084/m9.figshare.16682873
Mita-Mendoza, N. K., Magallón-Tejada, A., Parmar, P., Furtado, R., Aldrich, M., Saidi, A., Taylor, T., Smith, J., Seydel, K. B., & Daily, J. P. (2020) · Figshare · doi:10.6084/m9.figshare.13126425
Self-citationArroyo, H. A., Torres, A. R., Vidaurre, J. A., Rugilo, C., & Ho, M.-L. (2026) · Elsevier eBooks · doi:10.1016/b978-0-443-28722-0.00032-0
Riggle, B. A., Chamzas, A., Gopalakrishnan, M., Nyirenda, O. M., Nampota-Nkomba, N., Mallewa, J. E., Masonga, R., Manyozo, C., Zuze, K., Liomba, A. M., et al. (2026) · The Journal of Infectious Diseases · doi:10.1093/infdis/jiag121
Chaves, M. M., Barbosa, N. C., Savio, L. E. B., & Coutinho‐Silva, R. (2026) · Purinergic Signalling · doi:10.1007/s11302-026-10145-7
Anti-GPI scFv as a Promising Tool for Intervention Against Cerebral Malaria in Mice
Klein, S. G., Mota, K. C. P., Borges, B. C., Vieira, M. S., Neves, M. M., Mendes, L. S., Ferreira, F. B., de Lima, I. L., Santos, F. D. A. A., Bastos, L. M., et al. (2026) · International Journal of Molecular Sciences · doi:10.3390/ijms27072950
Alassane, N. S. K. (2016) · theses.fr (ABES) · doi:10.70675/358a746az8215z4e37z9c9cz3c55e7d7162a
Role of ATP2B4 and human malaria : looking for functional genetic variants associated with malaria
Nisar, S. (2020) · theses.fr (ABES) · doi:10.70675/74bb7b83zaf0dz45b5zb931z068c757b6e05
Malarial pneumonopathy in Malawian children with cerebral malaria
Wynkoop, H. J., Lintner-Rivera, M., Taylor, T., Seydel, K. B., Pensulo, P., Ayamie, M., Chetcuti, K., Vidal, L., & O'Brien, N. F. (2026) · Malaria Journal · doi:10.1186/s12936-026-05882-4
Self-citationLong-Term Neurocognitive Outcomes After Severe Malaria Infection
Sundararaman, S. A., & John, A. R. O. (2026) · JAMA · doi:10.1001/jama.2026.4290
Crotty, K. A., Clotea, I., Ueberheide, B. M., Cammer, M., Sall, J., Liang, A. F.-X., & Rodrı́guez, A. (2026) · mBio · doi:10.1128/mbio.00313-26
O'Brien, N. F., Postels, D. G., Chimalizeni, Y. F., Fonseca, Y., Wooldridge, G., Parker, E., Galeano, X., Urbina, E., Lintner-Rivera, M., Wynkoop, H. J., et al. (2026) · Neurocritical Care · doi:10.1007/s12028-026-02540-0
Self-citationSanches, G. S., Hakim, M. A., Brooks, S., Marins, T. D. S. B., Moreira, A. D. S., Gomes, F., Seara, F. D. A. C., Benoit-Smith, R., Daniel‐Ribeiro, C. T., Ponte, C. G., et al. (2026) · American Journal of Physiology-Heart and Circulatory Physiology · doi:10.1152/ajpheart.00262.2026
Gujarati, S., Singal, B. R., Majumder, S., Kochar, S. K., Kochar, D. K., & Das, A. (2026) · Frontiers in Microbiology · doi:10.3389/fmicb.2026.1846174
Chaudhary, A. K., Sharma, I., Thakur, R. S., Ranjha, R., & Das, J. (2026) · Acta Tropica · doi:10.1016/j.actatropica.2026.108223
Patel, A. A., Nishat, S., Joshi, R. B., Mwanza, S., Kasolo, J., Masempela, A., Musakanya, T., Mwale, T., Nambeye, V., Nyirongo, R., et al. (2026) · Journal of Central Nervous System Disease · doi:10.1177/11795735261467520
Self-citationBradykinin contributes to vasogenic edema in murine experimental cerebral malaria
Pinheiro, A. S., Teixeira¹, D. E., Silva-Aguiar, R. P., Shim, Y. J., Merkulova, A. A., Silbak, S., Skomorovska-Prokvolit, Y., Midem, D., Ogolla, S., Burckhardt, B. B., et al. (2026) · Journal of Clinical Investigation · doi:10.1172/jci202285
Domingo, N. D., Solomon, O. D., Villarreal, P., Aussenac, F., Vanegas, D., Endrino, M. J., Mendiola, A. S., Puebla-Clark, L., Gbédandé, K., Cardona, A. E., et al. (2026) · Journal of Neuroinflammation · doi:10.1186/s12974-026-03969-y · Cited by 1
Mad-adam, N., Kyaw, H. A., Poonsawaeng, I., Ketsawatsomkron, P., Bunbamrung, N., Pittayakhajonwut, P., Thawai, C., & Muta, K. (2026) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.64898/2026.09.10.750749
Oduro, D., Konadu, E. A., Obiri, D., Larbi, A. A., Thomas, A. K., Obese, A. O., Danso-Coffie, C., Yeboah, R., Yeboah, J. A., Baafour, E. K., et al. (2026) · Acta Tropica · doi:10.1016/j.actatropica.2026.108364
Metadata
- Authors
- Seydel, K. B., Kampondeni, S. D., Valim, C., Potchen, M. J., Milner, D. A., Muwalo, F. W., Birbeck, G. L., Bradley, W. G., Fox, L. L., Glover, S. J., Hammond, C. A., Heyderman, R. S., Chilingulo, C. A., Molyneux, M. E., & Taylor, T. E.
- Affiliations
- University of Malawi (MW)
- Harvard University (US)
- Michigan State University (US)
- Brigham and Women's Hospital (US)
- University of California San Diego (US)
- ORCID
- Venue
- New England Journal of Medicine
- Publisher
- Massachusetts Medical Society
- Published
- 2015-03-19
- Volume
- 372
- Issue
- 12
- Pages
- 1126-1137
- ISSN
- 0028-4793 (ISSN-L)
- 1533-4406
- PMC
- PMC4450675
- OpenAlex
- W2118846793
- Cited by
- 404
- References
- 43
- Citations by year
- 2026: 21 · 2025: 44 · 2024: 24 · 2023: 42 · 2022: 42 · 2021: 36 · 2020: 42 · 2019: 35 · 2018: 41 · 2017: 33 · 2016: 31 · 2015: 13
- FWCI
- 42.09
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- New England Journal of Medicine (publishedVersion)
- PubMed (publishedVersion)
- PubMed Central (acceptedVersion)
- Digital Access to Scholarship at Harvard (DASH) (Harvard University) (submittedVersion, cc-by)
- UCL Discovery (University College London) (submittedVersion)
- St Andrews Research Repository (St Andrews Research Repository) (submittedVersion)
- Funders
- Michigan State University
- Wellcome Trust (101113)
- National Institutes of Health
- College of Engineering, Michigan State University
- National Institute of Allergy and Infectious Diseases (R01AI034969)
- Topics
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Malaria Research and Control
- Health Sciences › Medicine › Infectious Diseases › Infectious Encephalopathies and Encephalitis
- Life Sciences › Immunology and Microbiology › Microbiology › Bacterial Infections and Vaccines
- Keywords
- cerebral malaria, cerebral edema, intracranial pressure, case fatality, pediatric malaria, retinopathy, brain volume, coma, natural history (disease)
- MeSH terms
- Brain, Brain Edema, Child, Child, Preschool, Female, Humans, Infant, Magnetic Resonance Imaging, Malawi, Male, Organ Size, Papilledema, Malaria, Cerebral
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
