The DOI matches its Crossref record; 31 of the 31 references it cites were found in a registry or an index.
Kidney-Failure Risk Projection for the Living Kidney-Donor Candidate
Open accessAbstract
BACKGROUND: Evaluation of candidates to serve as living kidney donors relies on screening for individual risk factors for end-stage renal disease (ESRD). To support an empirical approach to donor selection, we developed a tool that simultaneously incorporates multiple health characteristics to estimate a person's probable long-term risk of ESRD if that person does not donate a kidney. METHODS: We used risk associations from a meta-analysis of seven general population cohorts, calibrated to the population-level incidence of ESRD and mortality in the United States, to project the estimated long-term incidence of ESRD among persons who do not donate a kidney, according to 10 demographic and health characteristics. We then compared 15-year projections with the observed risk among 52,998 living kidney donors in the United States. RESULTS: A total of 4,933,314 participants from seven cohorts were followed for a median of 4 to 16 years. For a 40-year-old person with health characteristics that were similar to those of age-matched kidney donors, the 15-year projections of the risk of ESRD in the absence of donation varied according to race and sex; the risk was 0.24% among black men, 0.15% among black women, 0.06% among white men, and 0.04% among white women. Risk projections were higher in the presence of a lower estimated glomerular filtration rate, higher albuminuria, hypertension, current or former smoking, diabetes, and obesity. In the model-based lifetime projections, the risk of ESRD was highest among persons in the youngest age group, particularly among young blacks. The 15-year observed risks after donation among kidney donors in the United States were 3.5 to 5.3 times as high as the projected risks in the absence of donation. CONCLUSIONS: Multiple demographic and health characteristics may be used together to estimate the projected long-term risk of ESRD among living kidney-donor candidates and to inform acceptance criteria for kidney donors. (Funded by the National Institute of Diabetes and Digestive and Kidney Diseases and others.).
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Cites
Ahmed, A., Jorna, T., & Bhandari, S. (2016) · Nephron · doi:10.1159/000447068 · Cited by 11,717
Prediction of coronary heart disease using risk factor categories
Wilson, P. W. F., D’Agostino, R. B., Levy, D., Belanger, A. M., Silbershatz, H., & Kannel, W. B. (1998) · Circulation · doi:10.1161/01.cir.97.18.1837 · Cited by 9,581
Obesity and Kidney Disease: Hidden Consequences of the Epidemic
Kovesdy, C. P., Furth, S. L., Zoccali, C., & on behalf of the World Kidney Day Steering Committee (2017) · American Journal of Nephrology · doi:10.1159/000458467 · Cited by 2,217
Self-citationBody Mass Index and Risk for End-Stage Renal Disease
Hsu, C.-Y., McCulloch, C. E., Iribarren, C., Darbinian, J., & Go, A. S. (2006) · Annals of Internal Medicine · doi:10.7326/0003-4819-144-1-200601030-00006 · Cited by 1,390
Risk of End-Stage Renal Disease Following Live Kidney Donation
Muzaale, A. D., Massie, A. B., Wang, M.-C., Montgomery, R. A., McBride, M. A., Wainright, J. L., & Segev, D. L. (2014) · JAMA · doi:10.1001/jama.2013.285141 · Cited by 982
Self-citationLong-term risks for kidney donors
Mjøen, G., Hallan, S., Hartmann, A., Foss, A., Midtvedt, K., Øyen, O., Reisæter, A., Pfeffer, P., Jenssen, T., Leivestad, T., et al. (2014) · Kidney International · doi:10.1038/ki.2013.460 · Cited by 799
Meta-Analysis: Risk for Hypertension in Living Kidney Donors
Boudville, N., Ramesh Prasad, G. V., Knoll, G., Muirhead, N., Thiessen-Philbrook, H., Yang, R. C., Rosas-Arellano, M. P., Housawi, A., Garg, A. X., & for the Donor Nephrectomy Outcomes Research (DONOR) Network* (2006) · Annals of Internal Medicine · doi:10.7326/0003-4819-145-3-200608010-00006 · Cited by 394
Self-citationGestational Hypertension and Preeclampsia in Living Kidney Donors
Garg, A. X., Nevis, I., McArthur, E., Sontrop, J. M., Koval, J. J., Lam, N. N., Hildebrand, A. M., Reese, P. P., Storsley, L. J., Gill, J. S., et al. (2014) · New England Journal of Medicine · doi:10.1056/nejmoa1408932 · Cited by 353
Self-citationBody Mass Index in 1.2 Million Adolescents and Risk for End-Stage Renal Disease
Vivante, A., Golan, E., Tzur, D., Leiba, A., Tirosh, A., Skorecki, K., & Calderon-Margalit, R. (2012) · Archives of Internal Medicine · doi:10.1001/2013.jamainternmed.85 · Cited by 321
Cited by
Carey, R. M., Calhoun, D. A., Bakris, G. L., Brook, R. D., Daugherty, S. L., Dennison-Himmelfarb, C. R., Egan, B. M., Flack, J. M., Gidding, S. S., Judd, E., et al. (2018) · Hypertension · doi:10.1161/hyp.0000000000000084 · Cited by 1,153
Glomerular hyperfiltration in diabetes: mechanisms, clinical significance, and treatment
Tonneijck, L., Muskiet, M. H. A., Smits, M. M., van Bommel, E. J., Heerspink, H. J. L., van Raalte, D. H., & Joles, J. A. (2017) · Journal of the American Society of Nephrology · doi:10.1681/asn.2016060666 · Cited by 887
Tangri, N., Grams, M. E., Levey, A. S., Coresh, J., Appel, L. J., Astor, B. C., Chodick, G., Collins, A. J., Djurdjev, O., Elley, C. R., et al. (2016) · JAMA · doi:10.1001/jama.2015.18202 · Cited by 737
Self-citationKovesdy, C. P., Matsushita, K., Sang, Y., Brunskill, N. J., Carrero, J. J., Chodick, G., Hasegawa, T., Heerspink, H. L., Hirayama, A., Landman, G. W. D., et al. (2018) · European Heart Journal · doi:10.1093/eurheartj/ehy100 · Cited by 346
Self-citationMeasured and estimated glomerular filtration rate: current status and future directions
Levey, A. S., Coresh, J., Tighiouart, H., Greene, T., & Inker, L. A. (2020) · Nature Reviews Nephrology · doi:10.1038/s41581-019-0191-y · Cited by 312
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Metadata
- Authors
- Grams, M. E., Sang, Y., Levey, A. S., Matsushita, K., Ballew, S., Chang, A. R., Chow, E. K. H., Kasiske, B. L., Kovesdy, C. P., Nadkarni, G. N., Shalev, V., Segev, D. L., Coresh, J., Lentine, K. L., & Garg, A. X.
- Venue
- New England Journal of Medicine
- Publisher
- Massachusetts Medical Society
- Published
- 2016-02-04
- Volume
- 374
- Issue
- 5
- Pages
- 411-421
- ISSN
- 0028-4793 (ISSN-L)
- 1533-4406
- OpenAlex
- W2275619513
- Cited by
- 454
- References
- 31
- FWCI
- 44.32
- Type
- journal article
- Language
- en
- Open access
- bronze
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- Grams, M. E., Sang, Y., Levey, A. S., Matsushita, K., Ballew, S., Chang, A. R., Chow, E. K. H., Kasiske, B. L., Kovesdy, C. P., Nadkarni, G. N., Shalev, V., Segev, D. L., Coresh, J., Lentine, K. L., & Garg, A. X. (2016). Kidney-Failure Risk Projection for the Living Kidney-Donor Candidate. New England Journal of Medicine. https://doi.org/10.1056/nejmoa1510491
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