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One-Year Outcomes in Caregivers of Critically Ill Patients
Open accessAbstract
BACKGROUND: Few resources are available to support caregivers of patients who have survived critical illness; consequently, the caregivers' own health may suffer. We studied caregiver and patient characteristics to determine which characteristics were associated with caregivers' health outcomes during the first year after patient discharge from an intensive care unit (ICU). METHODS: We prospectively enrolled 280 caregivers of patients who had received 7 or more days of mechanical ventilation in an ICU. Using hospital data and self-administered questionnaires, we collected information on caregiver and patient characteristics, including caregiver depressive symptoms, psychological well-being, health-related quality of life, sense of control over life, and effect of providing care on other activities. Assessments occurred 7 days and 3, 6, and 12 months after ICU discharge. RESULTS: The caregivers' mean age was 53 years, 70% were women, and 61% were caring for a spouse. A large percentage of caregivers (67% initially and 43% at 1 year) reported high levels of depressive symptoms. Depressive symptoms decreased at least partially with time in 84% of the caregivers but did not in 16%. Variables that were significantly associated with worse mental health outcomes in caregivers were younger age, greater effect of patient care on other activities, less social support, less sense of control over life, and less personal growth. No patient variables were consistently associated with caregiver outcomes over time. CONCLUSIONS: In this study, most caregivers of critically ill patients reported high levels of depressive symptoms, which commonly persisted up to 1 year and did not decrease in some caregivers. (Funded by the Canadian Institutes of Health Research and others; ClinicalTrials.gov number, NCT00896220.).
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“and lead to psychological distress among family members (16).”
From Effects of a Personalized Web-Based Decision Aid for Surrogate Decision Makers of Patients With Prolonged Mechanical Ventilation (2019) · cites this paper as [16]
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“the clinical context was likely a challenge to careful decision making because of the sudden onset and rapid pace of critical illness, the proximity of possible death, the many clinicians involved with each patient, and the difficulties of deciding about life-sustaining therapy for a loved one (16).”
From Effects of a Personalized Web-Based Decision Aid for Surrogate Decision Makers of Patients With Prolonged Mechanical Ventilation (2019) · cites this paper as [16]
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The ABCDEF Bundle: Science and Philosophy of How ICU Liberation Serves Patients and Families
Ely, E. W. (2017) · Critical Care Medicine · doi:10.1097/ccm.0000000000002175 · Cited by 514
Mechanical Ventilation: State of the Art
Pham, T. O., Brochard, L. J., & Slutsky, A. S. (2017) · Mayo Clinic Proceedings · doi:10.1016/j.mayocp.2017.05.004 · Cited by 404
Self-citationComorbidities, multimorbidity and COVID-19
Russell, C. D., Lone, N., & Baillie, J. K. (2023) · Nature Medicine · doi:10.1038/s41591-022-02156-9 · Cited by 373
Carson, S. S., Cox, C. E., Wallenstein, S., Hanson, L. C., Danis, M., Tulsky, J. A., Chai, E., & Nelson, J. E. (2016) · JAMA · doi:10.1001/jama.2016.8474 · Cited by 352
Metadata
- Authors
- Cameron, J. I., Chu, L. M., Matte, A., Tomlinson, G., Chan, L., Thomas, C., Friedrich, J. O., Mehta, S., Lamontagne, F., Levasseur, M., Ferguson, N. D., Adhikari, N. K. J., Rudkowski, J. C., Meggison, H., Skrobik, Y., Flannery, J., Bayley, M., Batt, J., dos Santos, C., Abbey, S. E., Tan, A., Lo, V., Mathur, S., Parotto, M., Morris, D., Flockhart, L., Fan, E., Lee, C. M., Wilcox, M. E., Ayas, N., Choong, K., Fowler, R., Scales, D. C., Sinuff, T., Cuthbertson, B. H., Rose, L., Robles, P., Burns, S., Cypel, M., Singer, L., Chaparro, C., Chow, C.-W., Keshavjee, S., Brochard, L., Hébert, P., Slutsky, A. S., Marshall, J. C., Cook, D., & Herridge, M. S.
- Affiliations
- Mount Sinai Hospital (CA)
- ORCID
- Cameron, Jill I.
- Tomlinson, George
- Chan, Linda
- Friedrich, Jan O.
- Mehta, Sangeeta
- Ferguson, Niall D.
- Adhikari, Neill K.J.
- Rudkowski, Jill C.
- Meggison, Hilary
- Skrobik, Yoanna
- Flannery, John
- Bayley, Mark
- Batt, Jane
- Abbey, Susan E.
- Tan, Adrienne
- Mathur, Sunita
- Parotto, Matteo
- Morris, Denise
- Fan, Eddy
- Lee, Christie M.
- Wilcox, M. Elizabeth
- Ayas, Najib
- Choong, Karen
- Scales, Damon C.
- Cuthbertson, Brian H.
- Rose, Louise
- Robles, Priscila
- Burns, Stacey
- Cypel, Marcelo
- Singer, Lianne
- Chaparro, Cecilia
- Chow, Chung-Wai
- Keshavjee, Shaf
- Brochard, Laurent
- Hébert, Paul
- Slutsky, Arthur S.
- Marshall, John C.
- Herridge, Margaret S.
- Venue
- New England Journal of Medicine
- Publisher
- Massachusetts Medical Society
- Published
- 2016-05-12
- Volume
- 374
- Issue
- 19
- Pages
- 1831-1841
- ISSN
- 0028-4793 (ISSN-L)
- 1533-4406
- OpenAlex
- W2385708538
- Cited by
- 429
- References
- 50
- Citations by year
- 2026: 33 · 2025: 33 · 2024: 48 · 2023: 33 · 2022: 33 · 2021: 52 · 2020: 49 · 2019: 42 · 2018: 36 · 2017: 52 · 2016: 18
- FWCI
- 82.27
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- New England Journal of Medicine (publishedVersion)
- PubMed (publishedVersion)
- Funders
- University of Toronto
- Canadian Institutes of Health Research (97809_1)
- Topics
- Health Sciences › Medicine › Critical Care and Intensive Care Medicine › Family and Patient Care in Intensive Care Units
- Health Sciences › Nursing › Research and Theory › Nursing care and research
- Social Sciences › Psychology › Clinical Psychology › Family Caregiving in Mental Illness
- Keywords
- caregiver burden, family caregivers, critically ill patients, intensive care unit survivors, depressive symptoms, caregiver mental health, health-related quality of life, psychological well-being, social support, perceived control, personal growth, mechanical ventilation, post-discharge outcomes
- MeSH terms
- Adult, Aged, Depression, Family, Female, Humans, Male, Middle Aged, Prospective Studies, Quality of Life, Stress, Psychological, Critical Illness, Caregivers
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