Olanzapine for the prevention of chemotherapy-induced nausea and vomiting.
Open accessAbstract
BACKGROUND: We examined the efficacy of olanzapine for the prevention of nausea and vomiting in patients receiving highly emetogenic chemotherapy. METHODS: In a randomized, double-blind, phase 3 trial, we compared olanzapine with placebo, in combination with dexamethasone, aprepitant or fosaprepitant, and a 5-hydroxytryptamine type 3-receptor antagonist, in patients with no previous chemotherapy who were receiving cisplatin (≥70 mg per square meter of body-surface area) or cyclophosphamide-doxorubicin. The doses of the three concomitant drugs administered before and after chemotherapy were similar in the two groups. The two groups received either 10 mg of olanzapine orally or matching placebo daily on days 1 through 4. Nausea prevention was the primary end point; a complete response (no emesis and no use of rescue medication) was a secondary end point. RESULTS: In the analysis, we included 380 patients who could be evaluated (192 assigned to olanzapine, and 188 to placebo). The proportion of patients with no chemotherapy-induced nausea was significantly greater with olanzapine than with placebo in the first 24 hours after chemotherapy (74% vs. 45%, P=0.002), the period from 25 to 120 hours after chemotherapy (42% vs. 25%, P=0.002), and the overall 120-hour period (37% vs. 22%, P=0.002). The complete-response rate was also significantly increased with olanzapine during the three periods: 86% versus 65% (P<0.001), 67% versus 52% (P=0.007), and 64% versus 41% (P<0.001), respectively. Although there were no grade 5 toxic effects, some patients receiving olanzapine had increased sedation (severe in 5%) on day 2. CONCLUSIONS: Olanzapine, as compared with placebo, significantly improved nausea prevention, as well as the complete-response rate, among previously untreated patients who were receiving highly emetogenic chemotherapy. (Funded by the National Cancer Institute; ClinicalTrials.gov number, NCT02116530.).
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Olanzapine is associated with undesired sedation in some situations.
“With olanzapine being associated with undesired sedation in some situations, 15 it is interesting to note that there was decreased sedation and improved fatigue in the olanzapine arm.”
From Olanzapine for the Treatment of Advanced Cancer–Related Chronic Nausea and/or Vomiting: A Randomized Pilot Trial (2020) · cites this paper as [15]
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Group Sequential Methods with Applications to Clinical Trials
Jennison, C., & Turnbull, B. W. (1999) · Chapman & Hall/CRC eBooks · doi:10.1201/9780367805326 · Cited by 1,339 · see citing works
Radioreceptor Binding Profile of the Atypical Antipsychotic Olanzapine
Bymaster, F. P., Calligaro, D. O., Falcone, J. F., Marsh, R. D., Moore, N. A., Tye, N. C., Seeman, P. M., & Wong, D. T. (1996) · Neuropsychopharmacology · doi:10.1016/0893-133x(94)00129-n · Cited by 1,061 · see citing works
Antiemetics: American Society of Clinical Oncology Clinical Practice Guideline Update
Basch, E., Prestrud, A. A., Hesketh, P. J., Kris, M. G., Feyer, P., Somerfield, M. R., Chesney, M., Clark-Snow, R. A., Flaherty, A. M. C., Freundlich, B., et al. (2011) · Journal of Clinical Oncology · doi:10.1200/jco.2010.34.4614 · Cited by 1,058 · see citing works
Roila, F., Herrstedt, J., Aapro, M., Gralla, R. J., Einhorn, L. H., Ballatori, E., Bria, E., Clark-Snow, R. A., Espersen, B. T., Feyer, P., et al. (2010) · Annals of Oncology · doi:10.1093/annonc/mdq194 · Cited by 677 · see citing works
Antipsychotic-induced weight gain: a review of the literature.
Allison, D. B., & Casey, D. E. (2001) · PubMed · Cited by 596 · see citing works
Bloechl‐Daum, B., Deuson, R. R., Mavros, P., Hansen, M., & Herrstedt, J. (2006) · Journal of Clinical Oncology · doi:10.1200/jco.2006.05.6382 · Cited by 496 · see citing works
Navari, R. M., Gray, S. E., & Kerr, A. C. (2011) · The Journal of Supportive Oncology · doi:10.1016/j.suponc.2011.05.002 · Cited by 316 · see citing works
Self-citationAn Open Trial of Olanzapine for the Treatment of Delirium in Hospitalized Cancer Patients
BREITBART, W. S., Tremblay, A., & Gibson, C. (2002) · Psychosomatics · doi:10.1176/appi.psy.43.3.175 · Cited by 288 · see citing works
Modified intention to treat reporting in randomised controlled trials: systematic review
Abraha, I., & Montedori, A. (2010) · BMJ · doi:10.1136/bmj.c2697 · Cited by 257 · see citing works
Fulton, B., & Goa, K. L. (1997) · Drugs · doi:10.2165/00003495-199753020-00007 · Cited by 251 · see citing works
Aapro, M., Rugo, H. S., Rossi, A., Rizzi, G., Borroni, M. E., Bondarenko, I., Sarosiek, T., Oprean, C. M., Cardona‐Huerta, S., Lorusso, V., et al. (2014) · Annals of Oncology · doi:10.1093/annonc/mdu101 · Cited by 249 · see citing works
Hesketh, P. J., Rossi, A., Rizzi, G., Palmas, M., Alyasova, A. V., Bondarenko, I., Lisyanskaya, A. S., & Gralla, R. J. (2014) · Annals of Oncology · doi:10.1093/annonc/mdu110 · Cited by 228 · see citing works
New-Onset Diabetes Mellitus and Diabetic Ketoacidosis Associated With Olanzapine Treatment
Goldstein, L. E., Sporn, J., Brown, S., Kim, H., Finkelstein, J., Gaffey, G. K., Sachs, G. S., & Stern, T. A. (1999) · Psychosomatics · doi:10.1016/s0033-3182(99)71210-7 · Cited by 219 · see citing works
Jennison, C., & Turnbull, B. W. (1999) · Chapman & Hall/CRC machine learning & pattern recognition/Chapman & Hall/CRC machine learning & pattern recognition series · doi:10.1201/9781584888581 · Cited by 212 · see citing works
Clinical research of Olanzapine for prevention of chemotherapy-induced nausea and vomiting
Tan, L., Liu, J., Liu, X., Chen, J., Yan, Z., Yang, H., & Zhang, D. (2009) · Journal of Experimental & Clinical Cancer Research · doi:10.1186/1756-9966-28-131 · Cited by 199 · see citing works
Navari, R. M., Nagy, C. K., & Gray, S. E. (2013) · Supportive Care in Cancer · doi:10.1007/s00520-012-1710-6 · Cited by 181 · see citing works
Self-citationManagement of Chemotherapy-Induced Nausea and Vomiting
Navari, R. M. (2013) · Drugs · doi:10.1007/s40265-013-0019-1 · Cited by 174 · see citing works
Self-citationPassik, S. D., Lundberg, J., Kirsh, K. L., Theobald, D., Donaghy, K., Holtsclaw, E., Cooper, M., & Dugan, W. (2002) · Journal of Pain and Symptom Management · doi:10.1016/s0885-3924(02)00391-3 · Cited by 154 · see citing works
Schwartzberg, L. S., Modiano, M., Rapoport, B. L., Chasen, M. R., Gridelli, C., Urban, L., Poma, A., Arora, S., Navari, R. M., & Schnadig, I. D. (2015) · The Lancet Oncology · doi:10.1016/s1470-2045(15)00034-0 · Cited by 151 · see citing works
Self-citationNavari, R. M., Einhorn, L. H., Loehrer, P. J., Passik, S. D., Vinson, J., McClean, J., Chowhan, N. M., Hanna, N. H., & Johnson, C. S. (2007) · Supportive Care in Cancer · doi:10.1007/s00520-007-0248-5 · Cited by 149 · see citing works
Self-citationNavari, R. M., Einhorn, L. H., Passik, S. D., Loehrer, P. J., Johnson, C. S., Mayer, M. L., McClean, J., Vinson, J., & Pletcher, W. (2005) · Supportive Care in Cancer · doi:10.1007/s00520-004-0755-6 · Cited by 146 · see citing works
Self-citationAprepitant and Fosaprepitant: A 10-Year Review of Efficacy and Safety
Aapro, M., Carides, A. D., Rapoport, B. L., Schmoll, H., Zhang, L., & Warr, D. G. (2015) · The Oncologist · doi:10.1634/theoncologist.2014-0229 · Cited by 145 · see citing works
Rapoport, B. L., Chasen, M. R., Gridelli, C., Urban, L., Modiano, M., Schnadig, I. D., Poma, A., Arora, S., Kansra, V. V., Schwartzberg, L. S., et al. (2015) · The Lancet Oncology · doi:10.1016/s1470-2045(15)00035-2 · Cited by 138 · see citing works
Self-citationWhole brain radiotherapy with radiosensitizer for brain metastases
Viani, G. A., Manta, G. B., Fonseca, E. C., Fendi, L. I. D., Afonso, S., & Stefano, E. J. (2009) · Journal of Experimental & Clinical Cancer Research · doi:10.1186/1756-9966-28-1 · Cited by 135 · see citing works
Nausea : Mechanisms and Management
Stern, R. M., Koch, K. L., & Andrews, P. L. R. (2011) · Cited by 132 · see citing works
Potent antagonism of 5-HT3 and 5-HT6 receptors by olanzapine
Bymaster, F. P., Falcone, J. F., Bauzon, D., Kennedy, J. S., Schenck, K. W., DeLapp, N. W., & Cohen, M. L. (2001) · European Journal of Pharmacology · doi:10.1016/s0014-2999(01)01399-1 · Cited by 122 · see citing works
Mizukami, N., Yamauchi, M., Koike, K., Watanabe, A., Ichihara, K., Masumori, N., & Yamakage, M. (2013) · Journal of Pain and Symptom Management · doi:10.1016/j.jpainsymman.2013.05.003 · Cited by 116 · see citing works
Reduced Ghrelin Secretion in the Hypothalamus of Rats due to Cisplatin-Induced Anorexia
Yakabi, K., Sadakane, C., Noguchi, M., Ohno, S., Ro, S., Chinen, K., Aoyama, T., Sakurada, T., Takabayashi, H., & Hattori, T. (2010) · Endocrinology · doi:10.1210/en.2010-0061 · Cited by 110 · see citing works
Albany, C., Brames, M. J., Fausel, C. A., Johnson, C. S., Picus, J., & Einhorn, L. H. (2012) · Journal of Clinical Oncology · doi:10.1200/jco.2011.39.5558 · Cited by 108 · see citing works
Olanzapine as an antiemetic in refractory nausea and vomiting in advanced cancer.
Srivastava, M., Brito-Dellan, N., Davis, M. P., Leach, M., & Lagman, R. (2003) · Journal of Pain and Symptom Management · doi:10.1016/s0885-3924(03)00143-x · Cited by 106 · see citing works
Olanzapine in the Management of Cancer Pain
Khojainova, N., Santiago‐Palma, J., Kornick, C. A., BREITBART, W. S., & Gonzales, G. R. (2002) · Journal of Pain and Symptom Management · doi:10.1016/s0885-3924(02)00378-0 · Cited by 104 · see citing works
Shih, Y. T., Xu, Y., & Elting, L. S. (2007) · Cancer · doi:10.1002/cncr.22823 · Cited by 103 · see citing works
Passik, S. D., Navari, R. M., Jung, S., Nagy, C. K., Vinson, J., Kirsh, K. L., & Loehrer, P. J. (2004) · Cancer Investigation · doi:10.1081/cnv-200029066 · Cited by 102 · see citing works
Self-citationEinhorn, L. H., Brames, M. J., Dreicer, R., Nichols, C. R., Cullen, M. T., & Bubalo, J. S. (2007) · Supportive Care in Cancer · doi:10.1007/s00520-007-0255-6 · Cited by 92 · see citing works
Chemotherapy-Induced Nausea and Vomiting: Time for More Emphasis on Nausea?
Ng, T. L., Hutton, B. F., & Clemons, M. J. (2015) · The Oncologist · doi:10.1634/theoncologist.2014-0438 · Cited by 90 · see citing works
Navari, R. M. (2013) · European Journal of Pharmacology · doi:10.1016/j.ejphar.2013.08.048 · Cited by 87 · see citing works
Self-citationAnti-emetic activity of ghrelin in ferrets exposed to the cytotoxic anti-cancer agent cisplatin
Rudd, J. A., Ngan, M. P., Wai, M. K., King, A. G., Witherington, J. J., Andrews, P. L. R., & Sanger, G. J. (2005) · Neuroscience Letters · doi:10.1016/j.neulet.2005.08.062 · Cited by 82 · see citing works
Olanzapine for intractable nausea in palliative care patients.
Jackson, W. C., & Tavernier, L. (2003) · Journal of Palliative Medicine · doi:10.1089/109662103764978506 · Cited by 78 · see citing works
An open pilot trial of olanzapine for delirium in the Korean population
Kim, K., Pae, C., Chae, J., Bahk, W., & Jun, T. (2001) · Psychiatry and Clinical Neurosciences · doi:10.1046/j.1440-1819.2001.00898.x · Cited by 75 · see citing works
Olanzapine for chemotherapy-induced nausea and vomiting: a systematic review
Hocking, C. M., & Kichenadasse, G. (2014) · Supportive Care in Cancer · doi:10.1007/s00520-014-2138-y · Cited by 70 · see citing works
A pilot study of Interpersonal Psychotherapy by telephone with cancer patients and their partners
Donnelly, J. M., Kornblith, A. B., Fleishman, S., Zuckerman, E., Raptis, G., Hudis, C. A., Hamilton, N., Payne, D., Massie, M. J., Norton, L., et al. (2000) · Psycho-Oncology · doi:10.1002/(sici)1099-1611(200001/02)9:1 · Cited by 65 · see citing works
Börjeson, S., Hursti, T., Peterson, C., Fredikson, M., Fürst, C., Åvall-Lundqvist, E., & Steineck, G. (1997) · Cancer Nursing · doi:10.1097/00002820-199708000-00005 · Cited by 62 · see citing works
Passik, S. D., Kirsh, K. L., Theobald, D. E., Dickerson, P., Trowbridge, R., Gray, D., Beaver, M., Comparet, J., & Brown, J. (2003) · Journal of Pain and Symptom Management · doi:10.1016/s0885-3924(03)00078-2 · Cited by 56 · see citing works
Psychopharmacology of olanzapine
Stephenson, C., & Pilowsky, L. S. (1999) · The British Journal of Psychiatry · doi:10.1192/s0007125000298115 · Cited by 52 · see citing works
Why Do We Need Another Antiemetic? Just Ask.
Kris, M. G. (2003) · Journal of Clinical Oncology · doi:10.1200/jco.2003.07.968 · Cited by 52 · see citing works
Prevention of Emesis from Multiple-Day and High-Dose Chemotherapy Regimens
Navari, R. M. (2007) · Journal of the National Comprehensive Cancer Network · doi:10.6004/jnccn.2007.0007 · Cited by 51 · see citing works
Self-citationLorcaserin: An investigational serotonin 2C agonist for weight loss
Hurren, K. M., & Berlie, H. D. (2011) · American Journal of Health-System Pharmacy · doi:10.2146/ajhp100638 · Cited by 42 · see citing works
MASCC/ESMO Antiemetic Guidelines: Introduction to the 2016 guideline update
Molassiotis, A., Aapro, M., Herrstedt, J., Gralla, R. J., & Roila, F. (2016) · Supportive Care in Cancer · doi:10.1007/s00520-016-3324-x · Cited by 36 · see citing works
Fonte, C., Fatigoni, S., & Roila, F. (2015) · Critical Reviews in Oncology/Hematology · doi:10.1016/j.critrevonc.2015.02.010 · Cited by 32 · see citing works
Olanzapine: A New Antipsychotic Agent with Efficacy in the Management of Schizophrenia
Kando, J. C., Shepski, J. C., SATTERLEE, W. G., Patel, J. K., Reams, S. G., & Green, A. I. (1997) · Annals of Pharmacotherapy · doi:10.1177/106002809703101110 · Cited by 32 · see citing works
The current status of the use of palonosetron
Navari, R. M. (2013) · Expert Opinion on Pharmacotherapy · doi:10.1517/14656566.2013.799141 · Cited by 26 · see citing works
Self-citationNavari, R. M. (2014) · Drug Design Development and Therapy · doi:10.2147/dddt.s76158 · Cited by 25 · see citing works
Self-citationOlanzapine for nausea and vomiting.
Licup, N., & Baumrucker, S. (2010) · American Journal of Hospice and Palliative Medicine® · doi:10.1177/1049909110369532 · Cited by 23 · see citing works
Treatment of Chemotherapy-Induced Nausea
Navari, R. M. (2016) · Springer eBooks · doi:10.1007/978-3-319-27016-6_10 · Cited by 17 · see citing works
Self-citationRolapitant for the treatment of chemotherapy-induced nausea and vomiting
Navari, R. M. (2015) · Expert Review of Anticancer Therapy · doi:10.1586/14737140.2015.1088787 · Cited by 16 · see citing works
Self-citationHale, A. S. (1998) · PubMed · Cited by 14 · see citing works
Navari, R. M., Qin, R., Ruddy, K. J., Liu, H., Powell, S. F., Bajaj, M., Dietrich, L. L., Lafky, J. M., & Loprinzi, C. L. (2015) · Journal of Clinical Oncology · doi:10.1200/jco.2015.33.29_suppl.176 · Cited by 12 · see citing works
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Antiemetics: American Society of Clinical Oncology Clinical Practice Guideline Update
Hesketh, P. J., Kris, M. G., Basch, E., Bohlke, K., Barbour, S. Y., Clark-Snow, R. A., Danso, M. A., Dennis, K. E. B., Dupuis, L. L., Dusetzina, S. B., et al. (2017) · Journal of Clinical Oncology · doi:10.1200/jco.2017.74.4789 · Cited by 634 · see citing works
Burstein, H. J., Krilov, L., Aragon‐Ching, J. B., Baxter, N. N., Chiorean, E. G., Chow, W. A., Groot, J. F. D., Devine, S. M., DuBois, S. G., El‐Deiry, W. S., et al. (2017) · Journal of Clinical Oncology · doi:10.1200/jco.2016.71.5292 · Cited by 601 · see citing works
NCCN Guidelines Insights: Antiemesis, Version 2.2017
Berger, M. J., Ettinger, D. S., Aston, J., Barbour, S. Y., Bergsbaken, J., Bierman, P. J., Brandt, D. S., Dolan, D. E., Ellis, G., Kim, E. J., et al. (2017) · Journal of the National Comprehensive Cancer Network · doi:10.6004/jnccn.2017.0117 · Cited by 254 · see citing works
Self-citationDranitsaris, G., Molassiotis, A., Clemons, M. J., Roeland, E. J., Schwartzberg, L. S., Dielenseger, P., Jordan, K., Young, A., & Aapro, M. (2017) · Annals of Oncology · doi:10.1093/annonc/mdx100 · Cited by 238 · see citing works
Hashimoto, H., Abé, M., Tokuyama, O., Mizutani, H., Uchitomi, Y., Yamaguchi, T., Hoshina, Y., Sakata, Y., Takahashi, T. Y., Nakashima, K., et al. (2019) · The Lancet Oncology · doi:10.1016/s1470-2045(19)30678-3 · Cited by 229 · see citing works
Herrstedt, J., Clark-Snow, R. A., Ruhlmann, C. H. B., Molassiotis, A., Olver, I., Rapoport, B. L., Aapro, M., Dennis, K. E. B., Hesketh, P. J., Navari, R. M., et al. (2024) · ESMO Open · doi:10.1016/j.esmoop.2023.102195 · Cited by 206 · see citing works
Self-citationRazvi, Y., Chan, S., McFarlane, T., McKenzie, E., Zaki, P., DeAngelis, C., Pidduck, W., Bushehri, A., Chow, E., & Jerzak, K. J. (2018) · Supportive Care in Cancer · doi:10.1007/s00520-018-4464-y · Cited by 167 · see citing works
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Braun, I. M., Bohlke, K., Abrams, D. I., Anderson, H., Balneaves, L. G., Bar-Sela, G., Bowles, D. W., Chai, P. R., Damani, A., Gupta, A., et al. (2024) · Journal of Clinical Oncology · doi:10.1200/jco.23.02596 · Cited by 116 · see citing works
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Navari, R. M., Pywell, C. M., Le-Rademacher, J. G., White, P., Dodge, A. B., Albany, C., & Loprinzi, C. L. (2020) · JAMA Oncology · doi:10.1001/jamaoncol.2020.1052 · Cited by 78 · see citing works
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Yanai, T., Iwasa, S., Hashimoto, H., Ohyanagi, F., Takiguchi, T., Takeda, K., Nakao, M., Sakai, H., Nakayama, T., Minato, K., et al. (2017) · International Journal of Clinical Oncology · doi:10.1007/s10147-017-1200-4 · Cited by 74 · see citing works
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Sheng, J. Y.-S., Santa-Maria, C. A., Mangini, N. S., Norman, H., Couzi, R. J., Nunes, R., Wilkinson, M. J., Visvanathan, K., Connolly, R. M., Torres, E. T. R., et al. (2020) · JCO Oncology Practice · doi:10.1200/op.20.00364 · Cited by 66 · see citing works
Yoodee, J., Permsuwan, U., & Nimworapan, M. (2017) · Critical Reviews in Oncology/Hematology · doi:10.1016/j.critrevonc.2017.02.017 · Cited by 65 · see citing works
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Yokoe, T., Hayashida, T., Nagayama, A., Nakashoji, A., Maeda, H., Seki, T., Takahashi, M., Takano, T., Abe, T., & Kitagawa, Y. (2018) · The Oncologist · doi:10.1634/theoncologist.2018-0140 · Cited by 57 · see citing works
Kim, S.-D., Kwag, E.-B., Yang, M., & Yoo, H. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms231911267 · Cited by 55 · see citing works
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Self-citationBajpai, J., Kapu, V., Rath, S., Kumar, S., Sekar, A., Patil, P., Siddiqui, A., Srikanth, A., Pawar, A., Srinivas, S., et al. (2024) · The Lancet Oncology · doi:10.1016/s1470-2045(23)00628-9 · Cited by 46 · see citing works
van der Vorst, M. J. D. L., Neefjes, E. C. W., Toffoli, E. C., Oosterling-Jansen, J. E. W., Vergeer, M. R., Leemans, C. R., Kooistra, M. P., Voortman, J., & Verheul, H. M. W. (2019) · BMC Cancer · doi:10.1186/s12885-019-6233-9 · Cited by 46 · see citing works
Yang, T., Liu, Q., Lü, M., Ma, L., Zhou, Y. F., & Cui, Y. (2017) · British Journal of Clinical Pharmacology · doi:10.1111/bcp.13242 · Cited by 43 · see citing works
Herrstedt, J., Celio, L., Hesketh, P. J., Zhang, L., Navari, R. M., Chan, A., Saito, M., Chow, R., & Aapro, M. (2023) · Supportive Care in Cancer · doi:10.1007/s00520-023-08221-4 · Cited by 42 · see citing works
Self-citationYeo, W., Lau, T. K. H., Li, L., Lai, K. T., Pang, E., Cheung, M. S. H., Chan, V. T., Wong, C. Y., Soo, W. M. T., Yeung, V. T. Y., et al. (2020) · The Breast · doi:10.1016/j.breast.2020.01.005 · Cited by 42 · see citing works
Updates in Cancer Cachexia: Clinical Management and Pharmacologic Interventions
Pandey, S., Bradley, L., & Fabbro, E. D. (2024) · Cancers · doi:10.3390/cancers16091696 · Cited by 40 · see citing works
Sanomachi, T., Suzuki, S., Kuramoto, K., TAKEDA, H., Sakaki, H., Togashi, K., Seino, S., Yoshioka, T., Okada, M., & Kitanaka, C. (2017) · Anticancer Research · doi:10.21873/anticanres.12067 · Cited by 40 · see citing works
Celio, L., Bonizzoni, E., Zattarin, E., Codega, P., de Braud, F., & Aapro, M. (2019) · BMC Cancer · doi:10.1186/s12885-019-6454-y · Cited by 40 · see citing works
Clemons, M. J., Dranitsaris, G., Sienkiewicz, M., Sehdev, S. R., Ng, T. L., Robinson, A. G., Mates, M., Hsu, T., McGee, S. F., Freedman, O. C., et al. (2020) · The Breast · doi:10.1016/j.breast.2020.11.002 · Cited by 40 · see citing works
Chow, R., Herrstedt, J., Aapro, M., Chiu, L., Lam, H., Prsic, E. H., Lock, M. I., DeAngelis, C., & Navari, R. M. (2021) · Supportive Care in Cancer · doi:10.1007/s00520-020-05935-7 · Cited by 40 · see citing works
Self-citationMukhopadhyay, S., Kwatra, G., Kingsley, P. A., & Badyal, D. K. (2016) · Supportive Care in Cancer · doi:10.1007/s00520-016-3386-9 · Cited by 40 · see citing works
Psychiatric Care in Hematopoietic Stem Cell Transplantation
Nakamura, Z. M., Nash, R. P., Quillen, L. J., Richardson, D. R., McCall, R. C., & Park, E. M. (2019) · Psychosomatics · doi:10.1016/j.psym.2019.01.005 · Cited by 39 · see citing works
Zhao, Y., Yang, Y., Gao, F., Hu, C.-L., Zhong, D., Lu, M., Yuan, Z., Zhao, J., Miao, J., Li, Y., et al. (2022) · EClinicalMedicine · doi:10.1016/j.eclinm.2022.101771 · Cited by 38 · see citing works
Kennedy, S. K. F., Goodall, S., Lee, S. F., DeAngelis, C., Jocko, A., Charbonneau, F., Wang, K., Pasetka, M., Ko, Y., Wong, H. C. Y., et al. (2024) · Supportive Care in Cancer · doi:10.1007/s00520-024-08462-x · Cited by 38 · see citing works
Grimison, P., Mersiades, A. J., Kirby, A. C., Tognela, A., Olver, I., Morton, R. L., Haber, P., Walsh, A., Lee, Y., Abdi, E. A., et al. (2024) · Journal of Clinical Oncology · doi:10.1200/jco.23.01836 · Cited by 38 · see citing works
Management of Chemotherapy-Induced Nausea and Vomiting in Pediatric Patients
Navari, R. M. (2017) · Pediatric Drugs · doi:10.1007/s40272-017-0228-2 · Cited by 38 · see citing works
Self-citationCole, J. B., Klein, L. R., Strobel, A. M., Blanchard, S. R., Nahum, R., & Martel, M. L. (2017) · Pediatric Emergency Care · doi:10.1097/pec.0000000000001231 · Cited by 38 · see citing works
Tsuji, D., Suzuki, K., Kawasaki, Y., Goto, K., Matsui, R., Seki, N., Hashimoto, H., Hama, T., Yamanaka, T., Yamamoto, N., et al. (2018) · Supportive Care in Cancer · doi:10.1007/s00520-018-4403-y · Cited by 37 · see citing works
Behzadpour, N., Ranjbar, A., Azarpira, N., & Sattarahmady, N. (2020) · Ultrasound in Medicine & Biology · doi:10.1016/j.ultrasmedbio.2020.05.003 · Cited by 37 · see citing works
Tienchaiananda, P., Nipondhkit, W., Maneenil, K., Sa-nguansai, S., Payapwattanawong, S., Laohavinij, S., & Maneechavakajorn, J. (2019) · Annals of Palliative Medicine · doi:10.21037/apm.2019.08.04 · Cited by 37 · see citing works
Mikhael, J. R., Noonan, K., Faiman, B. M., Gleason, C. L., Nooka, A. K., Costa, L. J., Jagannath, S., Richardson, P. G. G., Siegel, D. S. D., Chari, A., et al. (2020) · Clinical Lymphoma Myeloma & Leukemia · doi:10.1016/j.clml.2019.12.026 · Cited by 36 · see citing works
Swetz, K. M., & Kamal, A. H. (2018) · Annals of Internal Medicine · doi:10.7326/aitc201803060 · Cited by 36 · see citing works
Tanaka, K., Inui, N., Karayama, M., Yasui, H., Hozumi, H., Suzuki, Y., Furuhashi, K., Fujisawa, T., Enomoto, N., Nakamura, Y., et al. (2019) · Cancer Chemotherapy and Pharmacology · doi:10.1007/s00280-019-03868-5 · Cited by 35 · see citing works
Managing Nutrition Impact Symptoms in Cancer Cachexia: A Case Series and Mini Review
Khorasanchi, A., Nemani, S., Pandey, S., & Fabbro, E. D. (2022) · Frontiers in Nutrition · doi:10.3389/fnut.2022.831934 · Cited by 35 · see citing works
Naik, R. D., Sreenivas, V., Singh, V., Pillai, A. S., Dhawan, D., & Bakhshi, S. (2020) · Journal of Clinical Oncology · doi:10.1200/jco.20.00871 · Cited by 34 · see citing works
Prevention of Chemotherapy-Induced Nausea and Vomiting in the Older Patient: Optimizing Outcomes
Herrstedt, J., Lindberg, S., & Petersen, P. C. (2021) · Drugs & Aging · doi:10.1007/s40266-021-00909-8 · Cited by 34 · see citing works
Recent advances in antiemetics: new formulations of 5HT3-receptor antagonists
Gilmore, J., D’Amato, S., Griffith, N. L., & Schwartzberg, L. S. (2018) · Cancer Management and Research · doi:10.2147/cmar.s166912 · Cited by 33 · see citing works
Flank, J., Sparavalo, J., Vol, H., Hagen, L., Stuhler, R., Chong, D., Courtney, S. W., Doyle, J., Gassas, A., Schechter, T., et al. (2017) · Bone Marrow Transplantation · doi:10.1038/bmt.2017.112 · Cited by 33 · see citing works
Hardy, J. R., Skerman, H. M., Glare, P. A., Philip, J. A. M., Hudson, P., Mitchell, G. K., Martin, P., Spruyt, O., Currow, D. C., & Yates, P. M. (2018) · BMC Cancer · doi:10.1186/s12885-018-4404-8 · Cited by 32 · see citing works
Olanzapine for the Prevention of Postdischarge Nausea and Vomiting after Ambulatory Surgery
Hyman, J. B., Park, C., Lin, H., Cole, B., Rosen, L., Fenske, S. S., Grzesh, R. L. B., Blank, S. V., Polsky, S. B., Hartnett, M., et al. (2020) · Anesthesiology · doi:10.1097/aln.0000000000003286 · Cited by 31 · see citing works
Zhang, Z., Zhang, Y., Chen, G., Hong, S., Yang, Y., Fang, W., Luo, F., Chen, X., Ma, Y., Zhao, Y., et al. (2018) · The Oncologist · doi:10.1634/theoncologist.2017-0378 · Cited by 31 · see citing works
Shen, G., Ren, D., Zhao, F., Wang, M., Liu, Z., Feng, X., He, Y., Liu, X., Ling, X., Zhao, Y., et al. (2024) · Journal of Clinical Oncology · doi:10.1200/jco.24.00099 · Cited by 30 · see citing works
Iihara, H., Shimokawa, M., Hayashi, T., Kawazoe, H., Saeki, T., Aiba, K., & Tamura, K. (2019) · The Oncologist · doi:10.1634/theoncologist.2019-0292 · Cited by 29 · see citing works
Otto, L., Strehle, L. D., Loman, B. R., Seng, M. M., Sardesai, S. D., Williams, N. O., Gatti-Mays, M. E., Stover, D. G., Sudheendra, P. K., Wesolowski, R., et al. (2024) · npj Breast Cancer · doi:10.1038/s41523-024-00707-6 · Cited by 28 · see citing works
AMPK β1 activation suppresses antipsychotic‐induced hyperglycemia in mice
Shamshoum, H., Medak, K. D., Townsend, L. K., Ashworth, K. E., Bush, N. D., Halm, M. K., Kemp, B. E., & Wright, D. C. (2019) · The FASEB Journal · doi:10.1096/fj.201901820r · Cited by 28 · see citing works
Zhou, J., Huang, L., Jin, S., Xu, C., Frey, B., Ma, H., & Gaipl, U. S. (2020) · ESMO Open · doi:10.1136/esmoopen-2019-000621 · Cited by 28 · see citing works
Ithimakin, S., Theeratrakul, P., Laocharoenkiat, A., Nimmannit, A., Akewanlop, C., Soparattanapaisarn, N., Techawattanawanna, S., Korphaisarn, K., & Danchaivijitr, P. (2020) · Supportive Care in Cancer · doi:10.1007/s00520-020-05380-6 · Cited by 28 · see citing works
Exercise Protects Against Olanzapine-Induced Hyperglycemia in Male C57BL/6J Mice
Castellani, L. N., Peppler, W. T., Miotto, P. M., Bush, N. D., & Wright, D. C. (2018) · Scientific Reports · doi:10.1038/s41598-018-19260-x · Cited by 28 · see citing works
Roeland, E. J., Ruddy, K. J., LeBlanc, T. W., Nipp, R. D., Binder, G., Sebastiani, S., Potluri, R. C., Schmerold, L. M., Papademetriou, E., Schwartzberg, L. S., et al. (2020) · Journal of the National Comprehensive Cancer Network · doi:10.6004/jnccn.2019.7526 · Cited by 28 · see citing works
Self-citationEvidence-based Palliative Care Approaches to Non-pain Physical Symptom Management in Cancer Patients
Hagmann, C. H., Cramer, A., Kestenbaum, A. R., Durazo, C., Downey, A., Russell, M., Geluz, J., JOSEPH, D. R., & Roeland, E. J. (2018) · Seminars in Oncology Nursing · doi:10.1016/j.soncn.2018.06.004 · Cited by 27 · see citing works
Harer, K. N., & Pasricha, P. J. (2016) · Current Treatment Options in Gastroenterology · doi:10.1007/s11938-016-0113-z · Cited by 27 · see citing works
Sakai, H., Tsurutani, J., Ozaki, Y., Ishiguro, H., Nozawa, K., Yamanaka, T., Aogi, K., Matsumoto, K., Iwasa, T., Tokiwa, M., et al. (2024) · Annals of Oncology · doi:10.1016/j.annonc.2024.09.001 · Cited by 26 · see citing works
Management of cisplatin-associated toxicities in bladder cancer patients
Desîlets, A., Adam, J., & Soulières, D. (2020) · Current Opinion in Supportive and Palliative Care · doi:10.1097/spc.0000000000000505 · Cited by 26 · see citing works
Smith, P., Lavery, A., & Turkington, R. C. (2020) · Best Practice & Research Clinical Gastroenterology · doi:10.1016/j.bpg.2020.101691 · Cited by 26 · see citing works
Trifilio, S. M., Welles, C., Seeger, K., Mehta, S. M., Fishman, M., McGowan, K., Strejcek, K., Eiten, E., Pirotte, C., Lucier, E., et al. (2017) · Clinical Lymphoma Myeloma & Leukemia · doi:10.1016/j.clml.2017.06.012 · Cited by 26 · see citing works
Jeon, S., Han, H. S., Bae, W. K., Park, M., Shim, H., Lee, S., Go, S., Yun, H., Im, Y., & Song, E. (2018) · Cancer Research and Treatment · doi:10.4143/crt.2017.577 · Cited by 26 · see citing works
The latest consensus on antiemetics
Herrstedt, J. (2018) · Current Opinion in Oncology · doi:10.1097/cco.0000000000000450 · Cited by 26 · see citing works
Cao, J., Ouyang, Q., Wang, S., Ragaz, J., Wang, X., Teng, Y., Wang, B., Wang, Z., Zhang, J., Wang, L., et al. (2020) · Investigational New Drugs · doi:10.1007/s10637-020-00903-8 · Cited by 26 · see citing works
Measurement of the amorphous fraction of olanzapine incorporated in a co-amorphous formulation
da Costa, N. F., Fernandes, A. I., & Pinto, J. F. (2020) · International Journal of Pharmaceutics · doi:10.1016/j.ijpharm.2020.119716 · Cited by 25 · see citing works
Improving cancer patient emergency room utilization: A New Jersey state assessment
Scholer, A. J., Mahmoud, O., Ghosh, D., Schwartzman, J., Farooq, M., Cabrera, J., Wieder, R., Adam, N. R., & Chokshi, R. J. (2017) · Cancer Epidemiology · doi:10.1016/j.canep.2017.09.006 · Cited by 25 · see citing works
Kawazoe, H., Murakami, A., Yamashita, M., Nishiyama, K., Kobayashi-Taguchi, K., Komatsu, S., Aoki, R., Kusakabe, E., Yamasawa, H., Yakushijin, Y., et al. (2018) · Clinical Therapeutics · doi:10.1016/j.clinthera.2018.10.004 · Cited by 25 · see citing works
Hayashi, T., Shimokawa, M., Matsuo, K., Miyoshi, T., Toriyama, Y., Yokota, C., Taniguchi, J., Hanada, K., Tsumagari, K., Okubo, N., et al. (2018) · Cancer Management and Research · doi:10.2147/cmar.s176574 · Cited by 24 · see citing works
Easing the Journey—an Updated Review of Palliative Care for the Patient with High-Grade Glioma
Crooms, R. C., Johnson, M. O., Leeper, H. E., Mehta, A. K., McWhirter, M., & Sharma, A. (2022) · Current Oncology Reports · doi:10.1007/s11912-022-01210-6 · Cited by 24 · see citing works
Nakashima, K., Murakami, H., Yokoyama, K., Omori, S., Wakuda, K., Ono, A., Kenmotsu, H., Naito, T., 西山史恵, 菊川真美, et al. (2017) · Japanese Journal of Clinical Oncology · doi:10.1093/jjco/hyx084 · Cited by 24 · see citing works
Hardy, J. R., Skerman, H. M., Philip, J. A. M., Good, P. D., Currow, D. C., Mitchell, G. K., & Yates, P. M. (2019) · BMJ Open · doi:10.1136/bmjopen-2019-029942 · Cited by 24 · see citing works
Hayashi, T., Shimokawa, M., Matsuo, K., Iihara, H., Kawada, K., Nakano, T., & Egawa, T. (2021) · BMC Cancer · doi:10.1186/s12885-021-07802-y · Cited by 24 · see citing works
van der Vorst, M. J. D. L., Toffoli, E. C., Beusink, M., Linde, M. E. V., van Voorthuizen, T., Brouwer, S., van Zweeden, A. A., Vrijaldenhoven, S., Berends, J. C., Berkhof, J. H., et al. (2020) · The Oncologist · doi:10.1634/theoncologist.2020-0305 · Cited by 23 · see citing works
Nakagaki, M., Barras, M. A., Curley, C. I., Butler, J., & Kennedy, G. (2016) · Supportive Care in Cancer · doi:10.1007/s00520-016-3445-2 · Cited by 23 · see citing works
Zhang, L., Qu, X., Teng, Y., Shi, J. C., Yu, P., Sun, T., Wang, J., Zhu, Z., Zhang, X., Zhao, M., et al. (2017) · Journal of Clinical Oncology · doi:10.1200/jco.2017.72.2538 · Cited by 23 · see citing works
Suzuki, S., Yamamoto, M., Togashi, K., Sanomachi, T., Sugai, A., Seino, S., Yoshioka, T., Kitanaka, C., & Okada, M. (2019) · Oncotarget · doi:10.18632/oncotarget.26949 · Cited by 23 · see citing works
Dupuis, L. L., TOMLINSON, G. A., Pong, A., Sung, L., & Bickham, K. L. (2020) · Journal of Clinical Oncology · doi:10.1200/jco.20.00134 · Cited by 23 · see citing works
Navari, R. M., Ruddy, K. J., LeBlanc, T. W., Nipp, R. D., Clark-Snow, R. A., Schwartzberg, L. S., Binder, G., Bailey, W. L., Potluri, R. C., Schmerold, L. M., et al. (2020) · The Oncologist · doi:10.1002/onco.13620 · Cited by 23 · see citing works
Self-citationVimolchalao, V., Sakdejayont, S., Wongchanapai, P., Sukprakun, S., Angspatt, P., Thawinwisan, W., Chenaksara, P., Sriuranpong, V., Vinayanuwatikun, C., Parinyanitikun, N., et al. (2019) · International Journal of Clinical Oncology · doi:10.1007/s10147-019-01570-3 · Cited by 23 · see citing works
Olanzapine as Antiemetic Prophylaxis in Moderately Emetogenic Chemotherapy
Ostwal, V. S., Ramaswamy, A., Mandavkar, S., BHARGAVA, P. G., Naughane, D., Sunn, S. F., Srinivas, S., Kapoor, A., Mishra, B. K., Gupta, A., et al. (2024) · JAMA Network Open · doi:10.1001/jamanetworkopen.2024.26076 · Cited by 22 · see citing works
Establishment of a research policy for supportive and palliative care in Japan
Zenda, S., Uchitomi, Y., Morita, T., Yamaguchi, T., & Inoue, A. (2021) · Japanese Journal of Clinical Oncology · doi:10.1093/jjco/hyab008 · Cited by 22 · see citing works
Wu, Z., Fu, X., Jing, H., Huang, W., Li, X., Xiao, C., Li, Z., & You, F. (2024) · Journal of Ethnopharmacology · doi:10.1016/j.jep.2024.117853 · Cited by 22 · see citing works
Belluomini, L., Avancini, A., Sposito, M., Pontolillo, L., Tregnago, D., Trestini, I., Insolda, J., Carbognin, L., Milella, M., Bria, E., et al. (2024) · Critical Reviews in Oncology/Hematology · doi:10.1016/j.critrevonc.2024.104444 · Cited by 21 · see citing works
Mechanisms and pharmacotherapy of cancer cachexia‐associated anorexia
Sato, R., da Fonseca, G. W. P., das Neves, W., & von Haehling, S. (2025) · Pharmacology Research & Perspectives · doi:10.1002/prp2.70031 · Cited by 21 · see citing works
Iihara, H., Shimokawa, M., Hayasaki, Y., Fujita, Y., Abé, M., Takenaka, M., Yamamoto, S., Arai, T., Sakurai, M., Mori, M., et al. (2020) · Gynecologic Oncology · doi:10.1016/j.ygyno.2020.01.004 · Cited by 21 · see citing works
Matsumoto, K., Takahashi, M., Sato, K., Osaki, A., Takano, T., Naito, Y., Matsuura, K., Aogi, K., Fujiwara, K., Tamura, K., et al. (2020) · Cancer Medicine · doi:10.1002/cam4.2979 · Cited by 20 · see citing works
Ten-Year Trends in Antiemetic Prescribing in Patients Receiving Highly Emetogenic Chemotherapy
O'Sullivan, C. C., Houten, H. K. V., Sangaralingham, L. R., Leal, A. D., Shinde, S. S., Liu, H., Ettinger, D. S., Loprinzi, C. L., & Ruddy, K. J. (2018) · Journal of the National Comprehensive Cancer Network · doi:10.6004/jnccn.2017.7043 · Cited by 19 · see citing works
Self-citationSanomachi, T., Suzuki, S., Togashi, K., Seino, S., Yoshioka, T., Kitanaka, C., Okada, M., & Yamamoto, M. (2019) · Anticancer Research · doi:10.21873/anticanres.13667 · Cited by 19 · see citing works
Mahendraratnam, N., Farley, J. F., Basch, E., Proctor, A., Wheeler, S. B., & Dusetzina, S. B. (2019) · Supportive Care in Cancer · doi:10.1007/s00520-019-04730-3 · Cited by 18 · see citing works
- Authors
- Navari, R. M., Qin, R., Ruddy, K. J., Liu, H., Powell, S. F., Bajaj, M., Dietrich, L., Biggs, D., Lafky, J. M., & Loprinzi, C. L.
- Affiliations
- Mayo Clinic (US)
- Venue
- New England Journal of Medicine
- Publisher
- Massachusetts Medical Society
- Published
- 2016-07-14
- Volume
- 375
- Issue
- 2
- Pages
- 134-142
- ISSN
- 0028-4793 (ISSN-L)
- 1533-4406
- PMC
- PMC5344450
- OpenAlex
- W2460792208
- Semantic Scholar
- e1dd1b394f61bd93ef976725f95376ef359b5a7d
- Cited by
- 452
- References
- 57
- Citations by year
- 2026: 28 · 2025: 46 · 2024: 56 · 2023: 43 · 2022: 36 · 2021: 39 · 2020: 54 · 2019: 34 · 2018: 54 · 2017: 52 · 2016: 9
- FWCI
- 55.02
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- New England Journal of Medicine (publishedVersion)
- PubMed (publishedVersion)
- PubMed Central (acceptedVersion)
- Purdue University Indianapolis (Indiana University) (submittedVersion)
- Funders
- National Institutes of Health
- National Cancer Institute (UG1CA189823, UG1CA189825, UG1CA189830, U10CA180790, U10CA180867, CA035269, U10CA035269, P50CA108961, UG1CA189956, UG1CA189819, P30CA012197, P30CA015083)
- National Center for Research Resources (M01RR000585, M01RR007122, M01RR000034)
- Topics
- Health Sciences › Medicine › Surgery › Nausea and vomiting management
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Pregnancy and Medication Impact
- Health Sciences › Medicine › Pathology and Forensic Medicine › Chemotherapy-induced organ toxicity mitigation
- Keywords
- olanzapine, chemotherapy-induced nausea and vomiting, antiemetic prophylaxis, highly emetogenic chemotherapy, cisplatin, dexamethasone, aprepitant, fosaprepitant, 5-HT3 receptor antagonists, sedation, complete response
- MeSH terms
- Olanzapine, Aprepitant, Adult, Aged, Aged, 80 and over, Antiemetics, Antineoplastic Agents, Benzodiazepines, Dexamethasone, Double-Blind Method, Drug Therapy, Combination, Female, Humans, Male, Middle Aged, Morpholines, Nausea, Vomiting, Intention to Treat Analysis
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