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The DOI matches its Crossref record; 30 of the 30 references it cites were found in a registry or an index.

Coronary-Artery Bypass Surgery in Patients with Ischemic Cardiomyopathy

Open access
Velazquez, Eric J., Lee, Kerry L., Jones, Robert H., Al-Khalidi, Hussein R., Hill, James A., Panza, Julio A., Michler, Robert E., Bonow, Robert O., Doenst, Torsten, Petrie, Mark C., Oh, Jae K., She, Lilin, Moore, Vanessa L., Desvigne-Nickens, Patrice, Sopko, George, Rouleau, Jean L.·2016·New England Journal of Medicine

Abstract

BACKGROUND: The survival benefit of a strategy of coronary-artery bypass grafting (CABG) added to guideline-directed medical therapy, as compared with medical therapy alone, in patients with coronary artery disease, heart failure, and severe left ventricular systolic dysfunction remains unclear. METHODS: From July 2002 to May 2007, a total of 1212 patients with an ejection fraction of 35% or less and coronary artery disease amenable to CABG were randomly assigned to undergo CABG plus medical therapy (CABG group, 610 patients) or medical therapy alone (medical-therapy group, 602 patients). The primary outcome was death from any cause. Major secondary outcomes included death from cardiovascular causes and death from any cause or hospitalization for cardiovascular causes. The median duration of follow-up, including the current extended-follow-up study, was 9.8 years. RESULTS: A primary outcome event occurred in 359 patients (58.9%) in the CABG group and in 398 patients (66.1%) in the medical-therapy group (hazard ratio with CABG vs. medical therapy, 0.84; 95% confidence interval [CI], 0.73 to 0.97; P=0.02 by log-rank test). A total of 247 patients (40.5%) in the CABG group and 297 patients (49.3%) in the medical-therapy group died from cardiovascular causes (hazard ratio, 0.79; 95% CI, 0.66 to 0.93; P=0.006 by log-rank test). Death from any cause or hospitalization for cardiovascular causes occurred in 467 patients (76.6%) in the CABG group and in 524 patients (87.0%) in the medical-therapy group (hazard ratio, 0.72; 95% CI, 0.64 to 0.82; P<0.001 by log-rank test). CONCLUSIONS: In a cohort of patients with ischemic cardiomyopathy, the rates of death from any cause, death from cardiovascular causes, and death from any cause or hospitalization for cardiovascular causes were significantly lower over 10 years among patients who underwent CABG in addition to receiving medical therapy than among those who received medical therapy alone. (Funded by the National Institutes of Health; STICH [and STICHES] ClinicalTrials.gov number, NCT00023595.).

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Metadata

Authors
Velazquez, E. J., Lee, K. L., Jones, R. H., Al-Khalidi, H. R., Hill, J. A., Panza, J. A., Michler, R. E., Bonow, R. O., Doenst, T., Petrie, M. C., Oh, J. K., She, L., Moore, V. L., Desvigne-Nickens, P., Sopko, G., & Rouleau, J. L.
Venue
New England Journal of Medicine
Published
2016-04-21
Volume
374
Issue
16
Pages
1511-1520
ISSN
  • 0028-4793 (ISSN-L)
  • 1533-4406
OpenAlex
W2319648922
Cited by
1,074
References
30
FWCI
99.57
Type
journal article
Language
en
Open access
bronze

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CoChat. (2026). Citation check: Coronary-Artery Bypass Surgery in Patients with Ischemic Cardiomyopathy. https://app.cochat.ai/papers/10.1056/nejmoa1602001
The paper
Velazquez, E. J., Lee, K. L., Jones, R. H., Al-Khalidi, H. R., Hill, J. A., Panza, J. A., Michler, R. E., Bonow, R. O., Doenst, T., Petrie, M. C., Oh, J. K., She, L., Moore, V. L., Desvigne-Nickens, P., Sopko, G., & Rouleau, J. L. (2016). Coronary-Artery Bypass Surgery in Patients with Ischemic Cardiomyopathy. New England Journal of Medicine. https://doi.org/10.1056/nejmoa1602001

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.