The DOI matches its Crossref record; 13 of the 13 references it cites were found in a registry or an index.
Radial-Artery or Saphenous-Vein Grafts in Coronary-Artery Bypass Surgery
Open accessAbstract
BACKGROUND: The use of radial-artery grafts for coronary-artery bypass grafting (CABG) may result in better postoperative outcomes than the use of saphenous-vein grafts. However, randomized, controlled trials comparing radial-artery grafts and saphenous-vein grafts have been individually underpowered to detect differences in clinical outcomes. We performed a patient-level combined analysis of randomized, controlled trials to compare radial-artery grafts and saphenous-vein grafts for CABG. METHODS: Six trials were identified. The primary outcome was a composite of death, myocardial infarction, or repeat revascularization. The secondary outcome was graft patency on follow-up angiography. Mixed-effects Cox regression models were used to estimate the treatment effect on the outcomes. RESULTS: A total of 1036 patients were included in the analysis (534 patients with radial-artery grafts and 502 patients with saphenous-vein grafts). After a mean (±SD) follow-up time of 60±30 months, the incidence of adverse cardiac events was significantly lower in association with radial-artery grafts than with saphenous-vein grafts (hazard ratio, 0.67; 95% confidence interval [CI], 0.49 to 0.90; P=0.01). At follow-up angiography (mean follow-up, 50±30 months), the use of radial-artery grafts was also associated with a significantly lower risk of occlusion (hazard ratio, 0.44; 95% CI, 0.28 to 0.70; P<0.001). As compared with the use of saphenous-vein grafts, the use of radial-artery grafts was associated with a nominally lower incidence of myocardial infarction (hazard ratio, 0.72; 95% CI, 0.53 to 0.99; P=0.04) and a lower incidence of repeat revascularization (hazard ratio, 0.50; 95% CI, 0.40 to 0.63; P<0.001) but not a lower incidence of death from any cause (hazard ratio, 0.90; 95% CI, 0.59 to 1.41; P=0.68). CONCLUSIONS: As compared with the use of saphenous-vein grafts, the use of radial-artery grafts for CABG resulted in a lower rate of adverse cardiac events and a higher rate of patency at 5 years of follow-up. (Funded by Weill Cornell Medicine and others.).
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Cites
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Self-citationRadial Artery Versus Saphenous Vein Patency Randomized Trial: Five-Year Angiographic Follow-Up
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Self-citationRadial Artery and Saphenous Vein Patency More Than 5 Years After Coronary Artery Bypass Surgery
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Self-citationLopes, R. D., Mehta, R. H., Hafley, G. E., Williams, J. B., Mack, M. J., Peterson, E. D., Allen, K. B., Harrington, R. A., Gibson, C. M., Califf, R. M., et al. (2012) · Circulation · doi:10.1161/circulationaha.111.040311 · Cited by 160
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2018 ESC/EACTS guidelines on myocardial revascularization
Neumann, F.-J., Sousa-Uva, M., Ahlsson, A., Alfonso, F., Banning, A. P., Benedetto, U., Byrne, R. A., Collet, J.-P., Falk, V., Head, S. J., et al. (2019) · European Heart Journal · doi:10.1093/eurheartj/ehy394 · Cited by 7,167
Self-citationCosentino, F., Grant, P. J., Aboyans, V., Bailey, C. J., Ceriello, A., Delgado, V., Federici, M., Filippatos, G., Grobbee, D. E., Hansen, T. B., et al. (2020) · European Heart Journal · doi:10.1093/eurheartj/ehz486 · Cited by 4,763
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2018 ESC/EACTS Guidelines on myocardial revascularization
Neumann, F.-J., Sousa-Uva, M., Ahlsson, A., Alfonso, F., Banning, A. P., Benedetto, U., Byrne, R. A., Collet, J.-P., Falk, V., Head, S. J., et al. (2019) · EuroIntervention · doi:10.4244/eijy19m01_01 · Cited by 1,259
Self-citation2018 ESC/EACTS Guidelines on myocardial revascularization
Sousa-Uva, M., Neumann, F.-J., Ahlsson, A., Alfonso, F., Banning, A. P., Benedetto, U., Byrne, R. A., Collet, J.-P., Falk, V., Head, S. J., et al. (2019) · European Journal of Cardio-Thoracic Surgery · doi:10.1093/ejcts/ezy289 · Cited by 989
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Metadata
- Authors
- Gaudino, M., Benedetto, U., Fremes, S., Biondi-Zoccai, G., Sedrakyan, A., Puskas, J. D., Angelini, G. D., Buxton, B., Frati, G., Hare, D. L., Hayward, P., Nasso, G., Moat, N., Peric, M., Yoo, K. J., Speziale, G., Girardi, L. N., & Taggart, D. P.
- Venue
- New England Journal of Medicine
- Publisher
- Massachusetts Medical Society
- Published
- 2018-05-31
- Volume
- 378
- Issue
- 22
- Pages
- 2069-2077
- ISSN
- 0028-4793 (ISSN-L)
- 1533-4406
- OpenAlex
- W2799568271
- Cited by
- 578
- References
- 13
- FWCI
- 75.41
- Type
- journal article
- Language
- en
- Open access
- bronze
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- Gaudino, M., Benedetto, U., Fremes, S., Biondi-Zoccai, G., Sedrakyan, A., Puskas, J. D., Angelini, G. D., Buxton, B., Frati, G., Hare, D. L., Hayward, P., Nasso, G., Moat, N., Peric, M., Yoo, K. J., Speziale, G., Girardi, L. N., & Taggart, D. P. (2018). Radial-Artery or Saphenous-Vein Grafts in Coronary-Artery Bypass Surgery. New England Journal of Medicine. https://doi.org/10.1056/nejmoa1716026
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