The DOI matches its Crossref record; 76 of the 76 references it cites were found in a registry or an index.
Reduced Lung-Cancer Mortality with Volume CT Screening in a Randomized Trial
Open accessAbstract
BACKGROUND: There are limited data from randomized trials regarding whether volume-based, low-dose computed tomographic (CT) screening can reduce lung-cancer mortality among male former and current smokers. METHODS: A total of 13,195 men (primary analysis) and 2594 women (subgroup analyses) between the ages of 50 and 74 were randomly assigned to undergo CT screening at T0 (baseline), year 1, year 3, and year 5.5 or no screening. We obtained data on cancer diagnosis and the date and cause of death through linkages with national registries in the Netherlands and Belgium, and a review committee confirmed lung cancer as the cause of death when possible. A minimum follow-up of 10 years until December 31, 2015, was completed for all participants. RESULTS: Among men, the average adherence to CT screening was 90.0%. On average, 9.2% of the screened participants underwent at least one additional CT scan (initially indeterminate). The overall referral rate for suspicious nodules was 2.1%. At 10 years of follow-up, the incidence of lung cancer was 5.58 cases per 1000 person-years in the screening group and 4.91 cases per 1000 person-years in the control group; lung-cancer mortality was 2.50 deaths per 1000 person-years and 3.30 deaths per 1000 person-years, respectively. The cumulative rate ratio for death from lung cancer at 10 years was 0.76 (95% confidence interval [CI], 0.61 to 0.94; P = 0.01) in the screening group as compared with the control group, similar to the values at years 8 and 9. Among women, the rate ratio was 0.67 (95% CI, 0.38 to 1.14) at 10 years of follow-up, with values of 0.41 to 0.52 in years 7 through 9. CONCLUSIONS: In this trial involving high-risk persons, lung-cancer mortality was significantly lower among those who underwent volume CT screening than among those who underwent no screening. There were low rates of follow-up procedures for results suggestive of lung cancer. (Funded by the Netherlands Organization of Health Research and Development and others; NELSON Netherlands Trial Register number, NL580.).
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
The cited source says what the claim attributes to it.
In the citing paper
“demonstrating that low-dose computed tomography substantially reduces deaths from lung cancer.”
From Global cancer statistics 2022: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. (2024) · cites this paper as [40]
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Bray, F., Ferlay, J., Soerjomataram, I., Siegel, R. L., Torre, L. A., & Jemal, A. (2018) · CA: A Cancer Journal for Clinicians · doi:10.3322/caac.21492 · Cited by 84,109
Siegel, R. L., Miller, K. D., & Jemal, A. (2018) · CA A Cancer Journal for Clinicians · doi:10.3322/caac.21442 · Cited by 16,632
Reduced Lung-Cancer Mortality with Low-Dose Computed Tomographic Screening
The National Lung Screening Trial Research Team (2011) · New England Journal of Medicine · doi:10.1056/nejmoa1102873 · Cited by 11,064
International Classification of Diseases for Oncology
National Cancer Institute (2020) · Definitions · doi:10.32388/1bjeus · Cited by 3,810
Early Lung Cancer Action Project: overall design and findings from baseline screening
Henschke, C. I., McCauley, D. I., Yankelevitz, D. F., Naidich, D. P., McGuinness, G., Miettinen, O. S., Libby, D. M., Pasmantier, M. W., Koizumi, J. H., Altorki, N. K., et al. (1999) · The Lancet · doi:10.1016/s0140-6736(99)06093-6 · Cited by 2,504
Mutation and Cancer: A Model for Human Carcinogenesis2
Moolgavkar, S. H., & Knudson, A. G. (1981) · JNCI Journal of the National Cancer Institute · doi:10.1093/jnci/66.6.1037 · Cited by 1,078
Mass screening for lung cancer with mobile spiral computed tomography scanner
Sone, S., Takashima, S., Li, F., Yang, Z., Honda, T., Maruyama, Y., Hasegawa, M., Yamanda, T., Kubo, K., Hanamura, K., et al. (1998) · The Lancet · doi:10.1016/s0140-6736(97)08229-9 · Cited by 931
Peripheral lung cancer: screening and detection with low-dose spiral CT versus radiography.
Kaneko, M., Eguchi, K., Ohmatsu, H., Kakinuma, R., Naruke, T., Suemasu, K., & Moriyama, N. (1996) · Radiology · doi:10.1148/radiology.201.3.8939234 · Cited by 832
Management of Lung Nodules Detected by Volume CT Scanning
van Klaveren, R. J., Oudkerk, M., Prokop, M., Scholten, E. T., Nackaerts, K., Vernhout, R. M., van Iersel, C. A., van den Bergh, K. A. M., Westeinde, S. C. V. ‘., van der Aalst, C. M., et al. (2009) · New England Journal of Medicine · doi:10.1056/nejmoa0906085 · Cited by 817
Self-citationOverdiagnosis in Low-Dose Computed Tomography Screening for Lung Cancer
Patz, E. F., Pinsky, P., Gatsonis, C., Sicks, J. D., Kramer, B. S., Tammemägi, M. C., Chiles, C., Black, W. C., & Aberle, D. R. (2014) · JAMA Internal Medicine · doi:10.1001/jamainternmed.2013.12738 · Cited by 776
Flagged first, then by citations
Cited by
Sorted by citations
Items 101–200 of 1,001
Chao, H., Shan, H., Homayounieh, F., Singh, R., Khera, R. D., Guo, H., Su, T., Wang, G., Kalra, M. K., & Yan, P. (2021) · Nature Communications · doi:10.1038/s41467-021-23235-4 · Cited by 116
Lung cancer is also a hereditary disease
Benusiglio, P. R., Fallet, V., Sanchis-Borja, M., Coulet, F., & Cadranel, J. L. (2021) · European Respiratory Review · doi:10.1183/16000617.0045-2021 · Cited by 111
Zhong, Y., She, Y., Deng, J., Chen, S., Wang, T., Yang, M., Ma, M., Song, Y., Qi, H., Wang, Y., et al. (2021) · Radiology · doi:10.1148/radiol.2021210902 · Cited by 104
Huang, B. L., Sollee, J., Luo, Y., Reddy, A., Zhong, Z., Wu, J., Mammarappallil, J. G., Healey, T. T., Cheng, G., Azzoli, C. G., et al. (2022) · EBioMedicine · doi:10.1016/j.ebiom.2022.104127 · Cited by 105
Blood-Based Biomarker Panel for Personalized Lung Cancer Risk Assessment
Fahrmann, J. F., Marsh, T. L., Irajizad, E., Patel, N. J., Murage, E. N., Vykoukal, J. V., Dennison, J. B., Do, K.-A., Ostrin, E. J., Spitz, M. R., et al. (2022) · Journal of Clinical Oncology · doi:10.1200/jco.21.01460 · Cited by 105
Patterns and Factors Associated With Adherence to Lung Cancer Screening in Diverse Practice Settings
Sakoda, L. C., Rivera, M. P., Zhang, J., Perera, P., Laurent, C. A., Durham, D. D., Huamani, R., Lane, L. M., Schwartz, A., Quesenberry, C. P., et al. (2021) · JAMA Network Open · doi:10.1001/jamanetworkopen.2021.8559 · Cited by 100
Montagne, F., Guisier, F., Vénissac, N., & Baste, J. (2021) · Cancers · doi:10.3390/cancers13153711 · Cited by 108
A comprehensive survey on convolutional neural network in medical image analysis
Yao, X., Wang, X., Wang, S., & Zhang, Y. (2020) · Multimedia Tools and Applications · doi:10.1007/s11042-020-09634-7 · Cited by 101
Lehman, C. D., D’Alessandro, H. A., Mendoza, D. P., Succi, M. D., Kambadakone, A. R., & Lamb, L. R. (2021) · Journal of the American College of Radiology · doi:10.1016/j.jacr.2021.03.001 · Cited by 95
Adherence to Follow-up Testing Recommendations in US Veterans Screened for Lung Cancer, 2015-2019
Núñez, E., Caverly, T. J., Zhang, S., Glickman, M. E., Qian, S. X., Boudreau, J., Slatore, C. G., Miller, D. R., & Wiener, R. S. (2021) · JAMA Network Open · doi:10.1001/jamanetworkopen.2021.16233 · Cited by 100
Osarogiagbon, R. U., Liao, W., Faris, N. R., Meadows-Taylor, M., Fehnel, C., Lane, J., Williams, S. C., Patel, A. A., Akinbobola, O. A., Pacheco, A., et al. (2022) · Journal of Clinical Oncology · doi:10.1200/jco.21.02496 · Cited by 95
Lung Cancer in Republic of China
Luo, Y., Chiu, C., Kuo, C.-H. S., Chou, T., Yeh, Y., Hsu, H., Yen, S.-H., Wu, Y., Yang, J. C., Liao, B.-C., et al. (2021) · Journal of Thoracic Oncology · doi:10.1016/j.jtho.2020.10.155 · Cited by 98
Wang, C., Shao, J., He, Y., Wu, J., Liu, X., Yang, L., Wei, Y., Zhou, X. S., Zhan, Y., Shi, F., et al. (2024) · Nature Medicine · doi:10.1038/s41591-024-03211-3 · Cited by 101
The Liquid Biopsy for Lung Cancer: State of the Art, Limitations and Future Developments
Capua, D. D., Bracken-Clarke, D. M., Ronan, K. E., Baird, A., & Finn, S. P. (2021) · Cancers · doi:10.3390/cancers13163923 · Cited by 98
Radiomics in Lung Diseases Imaging: State-of-the-Art for Clinicians
Frix, A.-N., Cousin, F., Refaee, T., Bottari, F., Vaidyanathan, A., Desir, C., Vos, W. G., Walsh, S., Occhipinti, M., Lovinfosse, P., et al. (2021) · Journal of Personalized Medicine · doi:10.3390/jpm11070602 · Cited by 93
Socio-Economic Inequalities in Lung Cancer Outcomes: An Overview of Systematic Reviews
Redondo‐Sánchez, D., Petrova, D., Rodríguez‐Barranco, M., Fernández‐Navarro, P., Jiménez‐Moleón, J. J., & Sánchez, M. (2022) · Cancers · doi:10.3390/cancers14020398 · Cited by 99
The blood proteome of imminent lung cancer diagnosis
Albanes, D., Alcala, K., Alcala, N., Amos, C. I., Arslan, A. A., Bassett, J. K., Brennan, P., Cai, Q., Chen, C., Feng, X., et al. (2023) · Nature Communications · doi:10.1038/s41467-023-37979-8 · Cited by 96
Plasma protein biomarkers for early prediction of lung cancer
Davies, M. P. A., Sato, T., Ashoor, H., Hou, L., Liloglou, T., Robert Che-An, Y. A. N. G., & Field, J. K. (2023) · EBioMedicine · doi:10.1016/j.ebiom.2023.104686 · Cited by 94
Artificial intelligence is improving the detection of lung cancer
Svoboda, E. (2020) · Nature · doi:10.1038/d41586-020-03157-9 · Cited by 99
Assessing Lung Cancer Absolute Risk Trajectory Based on a Polygenic Risk Model
Hung, R. J., Warkentin, M. T., Brhane, Y., Chatterjee, N., Christiani, D. C., Landi, M. T., Caporaso, N. E., Liu, G., Johansson, M., Albanes, D., et al. (2021) · Cancer Research · doi:10.1158/0008-5472.can-20-1237 · Cited by 91
Hines, J. B., Cameron, R. B., Esposito, A., Kim, L., Porcu, L., Nuccio, A., Viscardi, G., Ferrara, R., Veronesi, G., Forde, P. M., et al. (2024) · Journal of Thoracic Oncology · doi:10.1016/j.jtho.2024.03.010 · Cited by 96
Mazzone, P. J., Bach, P. B., Carey, J., Schonewolf, C. A., Bognar, K., Ahluwalia, M. S., Cruz-Correa, M. R., Gierada, D. S., Kotagiri, S., Lloyd, K., et al. (2024) · Cancer Discovery · doi:10.1158/2159-8290.cd-24-0519 · Cited by 91
Genomic and fragmentomic landscapes of cell-free DNA for early cancer detection
Bruhm, D. C., Vulpescu, N. A., Foda, Z. H., Phallen, J. A., Scharpf, R. B., & Velculescu, V. E. (2025) · Nature reviews. Cancer · doi:10.1038/s41568-025-00795-x · Cited by 110
Genotype-Specific Differences in Circulating Tumor DNA Levels in Advanced NSCLC
Lam, V. K. L., Zhang, J. J., Wu, C. C., Tran, H. T., Li, L., Diao, L., Wang, J., Rinsurongkawong, W., Raymond, V. M., Lanman, R. B., et al. (2020) · Journal of Thoracic Oncology · doi:10.1016/j.jtho.2020.12.011 · Cited by 89
Stage Shift Improves Lung Cancer Survival: Real-World Evidence
Yang, C., Lin, Y., Lin, L., Chang, Y.-H., Chen, H., Wang, Y., Shih, J., Yu, C., & Yang, P. (2022) · Journal of Thoracic Oncology · doi:10.1016/j.jtho.2022.09.005 · Cited by 91
Brodersen, J., Voss, T., Martiny, F., Siersma, V., Barratt, A. L., & Heleno, B. (2020) · Breathe · doi:10.1183/20734735.0013-2020 · Cited by 89
Sadate, A., Occéan, B., Bérégi, J.-P., Hamard, A., Addala, T., de Forges, H., Fabbro-Péray, P., & Frandon, J. (2020) · European Journal of Cancer · doi:10.1016/j.ejca.2020.04.035 · Cited by 90
Schreuder, A., Scholten, E. T., van Ginneken, B., & Jacobs, C. (2021) · Translational Lung Cancer Research · doi:10.21037/tlcr-2020-lcs-06 · Cited by 94
Self-citationCrosbie, P. A. J., Gabe, R., Simmonds, I., Kennedy, M., Rogerson, S., Ahmed, N., Baldwin, D., Booton, R., Cochrane, A., Darby, M. J., et al. (2020) · BMJ Open · doi:10.1136/bmjopen-2020-037075 · Cited by 87
Hendrix, W., Hendrix, N., Scholten, E. T., Mourits, M., Jong, J. T.-D., Schalekamp, S., Korst, M. B. J. M., van Leuken, M. H., van Ginneken, B., Prokop, M., et al. (2023) · Communications Medicine · doi:10.1038/s43856-023-00388-5 · Cited by 96
Self-citationCancer Stage Compared With Mortality as End Points in Randomized Clinical Trials of Cancer Screening
Feng, X., Zahed, H., Onwuka, J. U., Callister, M. E. J., Johansson, M., Etzioni, R., & Robbins, H. A. (2024) · JAMA · doi:10.1001/jama.2024.5814 · Cited by 89
The smell of lung disease: a review of the current status of electronic nose technology
van der Sar, I. G., Wijbenga, N., Nakshbandi, G., Aerts, J. G. J. V., Manintveld, O. C., Wijsenbeek, M. S., Hellemons, M. E., & Moor, C. C. (2021) · Respiratory Research · doi:10.1186/s12931-021-01835-4 · Cited by 87
Self-citationA Viral Exposure Signature Defines Early Onset of Hepatocellular Carcinoma
Liu, J., Tang, W., Budhu, A., Forgues, M., Hernandez, M. O., Candia, J., Kim, Y., Bowman, E. D., Ambs, S., Zhao, Y., et al. (2020) · Cell · doi:10.1016/j.cell.2020.05.038 · Cited by 86
The evolving landscape of sex-based differences in lung cancer: a distinct disease in women
Ragavan, M. V., & Patel, M. I. (2022) · European Respiratory Review · doi:10.1183/16000617.0100-2021 · Cited by 88
Contribution of adaptive immunity to human COPD and experimental models of emphysema
Kheradmand, F., Zhang, Y., & Corry, D. B. (2022) · Physiological Reviews · doi:10.1152/physrev.00036.2021 · Cited by 87
Yang, X., Man, J., Chen, H., Zhang, T., Yin, X., He, Q., & Lü, M. (2020) · Lung Cancer · doi:10.1016/j.lungcan.2020.12.007 · Cited by 89
Huang, H. B., Wu, R., Li, Y., & Peng, C. (2022) · IEEE Journal of Biomedical and Health Informatics · doi:10.1109/jbhi.2022.3171851 · Cited by 84
Artificial Intelligence Tool for Assessment of Indeterminate Pulmonary Nodules Detected with CT
Kim, R. Y., Oke, J. L., Pickup, L., Munden, R. F., Dotson, T. L., Bellinger, C., Cohen, A., Simoff, M., Massion, P. P., Filippini, C., et al. (2022) · Radiology · doi:10.1148/radiol.212182 · Cited by 87
Low, S., Lentz, R. J., Chen, H., Katsis, J. M., Aboudara, M. C., Whatley, S., Paez, R., Rickman, O. B., & Maldonado, F. (2022) · CHEST Journal · doi:10.1016/j.chest.2022.10.019 · Cited by 83
The present and future of cough counting tools
Hall, J., Lozano, M., Estrada, L., Birring, S. S., & Turner, R. D. (2020) · Journal of Thoracic Disease · doi:10.21037/jtd-2020-icc-003 · Cited by 82
Lung cancer screening and smoking cessation efforts
Moldovanu, D., de Koning, H. J., & van der Aalst, C. M. (2021) · Translational Lung Cancer Research · doi:10.21037/tlcr-20-899 · Cited by 82
Zhou, B., Zang, R., Zhang, M., Song, P., Liu, L., Bie, F., Peng, Y., Bai, G., & Gao, S. (2022) · EBioMedicine · doi:10.1016/j.ebiom.2022.103951 · Cited by 82
Osaid, Z., Haider, M. A., Hamoudi, R., & Harati, R. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms242115635 · Cited by 89
The importance of long-term follow up of participants in clinical trials
Cuzick, J. (2023) · British Journal of Cancer · doi:10.1038/s41416-022-02038-4 · Cited by 101
Cao, P., Jeon, J., Levy, D. T., Jayasekera, J. C., Cadham, C. J., Mandelblatt, J. S., Taylor, K. L., & Meza, R. (2020) · Journal of Thoracic Oncology · doi:10.1016/j.jtho.2020.02.008 · Cited by 81
Ruparel, M., Quaife, S. L., Dickson, J. L., Horst, C., Tisi, S., Hall, H., Taylor, M. N., Ahmed, A., Shaw, P. J., Burke, S. J., et al. (2020) · Annals of the American Thoracic Society · doi:10.1513/annalsats.201911-857oc · Cited by 83
Chelala, L., Hossain, R., Kazerooni, E. A., Christensen, J. D., Dyer, D. S., & WHITE, C. S. (2021) · American Journal of Roentgenology · doi:10.2214/ajr.20.24807 · Cited by 84
Chao, H., Shan, H., Homayounieh, F., Singh, R., Khera, R. D., Guo, H., Su, T., Wang, G., Kalra, M. K., & Yan, P. (2021) · RePEc: Research Papers in Economics · Cited by 81
Biomarkers and Lung Cancer Early Detection: State of the Art
Dama, E., Colangelo, T., Fina, E., Cremonesi, M., Kallikourdis, M., Veronesi, G., & Bianchi, F. (2021) · Cancers · doi:10.3390/cancers13153919 · Cited by 84
Lam, S. C., Bai, C., Baldwin, D., Chen, Y., Connolly, C., de Koning, H. J., Heuvelmans, M. A., Hu, P., Kazerooni, E. A., Lancaster, H. L., et al. (2023) · Journal of Thoracic Oncology · doi:10.1016/j.jtho.2023.07.019 · Cited by 90
Self-citationArtificial Intelligence and Machine Learning in Radiology
Wichmann, J. L., Willemink, M. J., & Cecco, C. N. D. (2020) · Investigative Radiology · doi:10.1097/rli.0000000000000673 · Cited by 85
Personalising lung cancer screening: An overview of risk‐stratification opportunities and challenges
ten Haaf, K., van der Aalst, C. M., de Koning, H. J., Kaaks, R., & Tammemägi, M. C. (2021) · International Journal of Cancer · doi:10.1002/ijc.33578 · Cited by 80
Passiglia, F., Cinquini, M., Bertolaccini, L., Re, M. D., Facchinetti, F., Ferrara, R., Franchina, T., Larici, A. R., Malapelle, U., Menis, J., et al. (2021) · Journal of Clinical Oncology · doi:10.1200/jco.20.02574 · Cited by 79
Liquid biopsy and non-small cell lung cancer: are we looking at the tip of the iceberg?
Bonanno, L., Maso, A. D., Pavan, A., Zulato, E., Calvetti, L., Pasello, G., Guarneri, V., Conte, P., & Indraccolo, S. (2022) · British Journal of Cancer · doi:10.1038/s41416-022-01777-8 · Cited by 81
Liao, W., Coupland, C. A. C., Burchardt, J., Baldwin, D., Gleeson, F. V., Baldwin, D., Batchkala, G., Buchanan, J., Burchardt, J., Chakraborty, R., et al. (2023) · The Lancet Respiratory Medicine · doi:10.1016/s2213-2600(23)00050-4 · Cited by 80
Grant-Orser, A., Min, B., Elmrayed, S. A., Podolanczuk, A. J., & Johannson, K. A. (2023) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/rccm.202302-0271oc · Cited by 79
Low-Dose CT Screening for Lung Cancer: Evidence from 2 Decades of Study
Gierada, D. S., Black, W. C., Chiles, C., Pinsky, P. F., & Yankelevitz, D. F. (2020) · Radiology Imaging Cancer · doi:10.1148/rycan.2020190058 · Cited by 79
Diagnosing Non-Small Cell Lung Cancer by Exhaled Breath Profiling Using an Electronic Nose
Kort, S., Brusse-Keizer, M. G. J., Schouwink, H., Citgez, E., de Jongh, F. H., van Putten, J. W. G., van den Borne, B., Kastelijn, E. A., Stolz, D., Schuurbiers, M. M. F., et al. (2022) · CHEST Journal · doi:10.1016/j.chest.2022.09.042 · Cited by 78
Lin, C.-Y., Guo, S., Lien, J.-J. J., Lin, W.-T., Liu, Y., Lai, C., Hsu, I.-L., Chang, C., & Tseng, Y. (2023) · La radiologia medica · doi:10.1007/s11547-023-01730-6 · Cited by 82
ACR Lung-RADS v2022: Assessment Categories and Management Recommendations
Christensen, J. D., Prosper, A. E., Wu, C. C., Chung, J. H., Lee, E., Elicker, B. M., Hunsaker, A. R., Petranović, M., Sandler, K. L., Stiles, B. M., et al. (2024) · CHEST Journal · doi:10.1016/j.chest.2023.10.028 · Cited by 83
Lung cancer incidence and mortality with extended follow-up in the National Lung Screening Trial
Frille, A., Hardavella, G. F., & Lee, R. E., Jr. (2020) · Breathe · doi:10.1183/20734735.0322-2019 · Cited by 76
Diagnostic Outcomes and Safety of Cryobiopsy Added to Conventional Sampling Methods
Matsumoto, Y., Nakai, T., Tanaka, M., Imabayashi, T., Tsuchida, T., & Ohe, Y. (2021) · CHEST Journal · doi:10.1016/j.chest.2021.05.015 · Cited by 76
Stage Migration and Lung Cancer Incidence After Initiation of Low-Dose Computed Tomography Screening
Vachani, A., Carroll, N. M., Simoff, M., Neslund-Dudas, C. M., Honda, S., Greenlee, R. T., Rendle, K. A. S., Burnett‐Hartman, A. N., & Ritzwoller, D. P. (2022) · Journal of Thoracic Oncology · doi:10.1016/j.jtho.2022.08.011 · Cited by 77
Brunelli, A., Decaluwé, H., González, M., Gossot, D., Petersen, R. H., Augustin, F., Assouad, J., Baste, J. M., Batırel, H. F., Falcoz, P., et al. (2023) · European Journal of Cardio-Thoracic Surgery · doi:10.1093/ejcts/ezad224 · Cited by 76
Systematic Review of Lung Cancer Screening: Advancements and Strategies for Implementation
Amicizia, D., Piazza, M. F., Marchini, F., Astengo, M., Grammatico, F., Battaglini, A., Schenone, I., Sticchi, C., Lavieri, R., Silverio, B. D., et al. (2023) · Healthcare · doi:10.3390/healthcare11142085 · Cited by 76
Both Duration and Pack-Years of Tobacco Smoking Should Be Used for Clinical Practice and Research
Pleasants, R. A., Rivera, M. P., Tilley, S. L., & Bhatt, S. P. (2020) · Annals of the American Thoracic Society · doi:10.1513/annalsats.202002-133vp · Cited by 75
van Assen, M., Martin, S. S., Varga‐Szemes, Á., Rapaka, S., Çimen, S., Sharma, P., Sahbaee, P., Cecco, C. N. D., Vliegenthart, R., Leonard, T. J., et al. (2020) · European Journal of Radiology · doi:10.1016/j.ejrad.2020.109428 · Cited by 75
Self-citationAge at diagnosis for lung, colon, breast and prostate cancers: An international comparative study
Zahed, H., Feng, X., Sheikh, M., Bray, F., Ferlay, J., Ginsburg, O., Shiels, M. S., & Robbins, H. A. (2023) · International Journal of Cancer · doi:10.1002/ijc.34671 · Cited by 89
Hallmarks of artificial intelligence contributions to precision oncology
Chang, T., Park, S., Schäffer, A. A., Jiang, P., & Ruppin, E. (2025) · Nature Cancer · doi:10.1038/s43018-025-00917-2 · Cited by 83
Liverpool Lung Project lung cancer risk stratification model: calibration and prospective validation
Field, J. K., Vulkan, D., Davies, M. P. A., Duffy, S. W., & Gabe, R. (2020) · Thorax · doi:10.1136/thoraxjnl-2020-215158 · Cited by 74
Artificial Intelligence in Lung Cancer Imaging: Unfolding the Future
Cellina, M. I., Cè, M., Irmici, G., Ascenti, V., Khenkina, N., Toto‐Brocchi, M., Martinenghi, C. M. A., Papa, S., & Carrafiello, G. (2022) · Diagnostics · doi:10.3390/diagnostics12112644 · Cited by 81
Organized Lung Cancer Screening Pilot: Informing a Province-Wide Program in Ontario, Canada
Darling, G. E., Tammemägi, M. C., Schmidt, H., Buchanan, D. N., Leung, Y. W., McGarry, C., & Rabeneck, L. (2020) · The Annals of Thoracic Surgery · doi:10.1016/j.athoracsur.2020.07.051 · Cited by 72
Potter, A. L., Costantino, C. L., Suliman, R. A., Haridas, C., Senthil, P., Kumar, A., Mayne, N. R., Panda, N., Martin, L. W., & Yang, C. J. (2023) · The Annals of Thoracic Surgery · doi:10.1016/j.athoracsur.2023.06.004 · Cited by 74
Lee, E. H., & Kazerooni, E. A. (2022) · Seminars in Respiratory and Critical Care Medicine · doi:10.1055/s-0042-1757885 · Cited by 71
Metal Nanoparticles as Novel Agents for Lung Cancer Diagnosis and Therapy
Zheng, X., Wu, Y. K., Zuo, H., Chen, W., & Wang, K. (2023) · Small · doi:10.1002/smll.202206624 · Cited by 71
Peng, A. W., Dudum, R., Jain, S. S., Maron, D. J., Patel, B. N., Khandwala, N., Eng, D., Chaudhari, A. S., Sandhu, A. T., & Rodriguez, F. (2023) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2023.06.040 · Cited by 67
Lung Cancer in Women: The Past, Present, and Future
Florez, N., Kiel, L., Riaño, I., Patel, S. R., DeCarli, K., Dhawan, N., Franco, I., Odai-Afotey, A. A., Meza, K., Swami, N. S., et al. (2023) · Clinical Lung Cancer · doi:10.1016/j.cllc.2023.10.007 · Cited by 77
Cadham, C. J., Cao, P., Jayasekera, J. C., Taylor, K. L., Levy, D. T., Jeon, J., Elkin, E. B., Foley, K. L., Joseph, A. M., Kong, C. Y., et al. (2021) · JNCI Journal of the National Cancer Institute · doi:10.1093/jnci/djab002 · Cited by 70
Shared Decision-Making for Lung Cancer Screening
Nishi, S. P. E., Lowenstein, L. M., Mendoza, T. R., Lopez-Olivo, M. A., Crocker, L. C., Sepucha, K., Niu, J., & Volk, R. J. (2021) · CHEST Journal · doi:10.1016/j.chest.2021.01.041 · Cited by 69
Tammemägi, M., Ruparel, M., Tremblay, A., Myers, R., Mayo, J., Yee, J., Atkar-Khattra, S., Yuan, R., Cressman, S., English, J., et al. (2022) · UCL Discovery (University College London) · Cited by 69
Radiomics in Early Lung Cancer Diagnosis: From Diagnosis to Clinical Decision Support and Education
Wu, Y.-J., Wu, F., Yang, S.-C., Tang, E., & Liang, C.-H. (2022) · Diagnostics · doi:10.3390/diagnostics12051064 · Cited by 74
Risk Model–Based Lung Cancer Screening and Racial and Ethnic Disparities in the US
Choi, E., Ding, V. Y., Luo, S. J., ten Haaf, K., Wu, J. T.-Y., Aredo, J. V., Wilkens, L. R., Freedman, N. D., Backhus, L. M., Leung, A. N. C., et al. (2023) · JAMA Oncology · doi:10.1001/jamaoncol.2023.4447 · Cited by 69
Cancer screening with multicancer detection tests: A translational science review
Rubinstein, W. S., Patriotis, C., Dickherber, A. J., Han, P. K. J., Katki, H. A., LeeVan, E. M., Pinsky, P. F., Prorok, P. C., Skarlupka, A. L., Temkin, S. M., et al. (2024) · CA A Cancer Journal for Clinicians · doi:10.3322/caac.21833 · Cited by 70
The 2021 USPSTF lung cancer screening guidelines: a new frontier
Potter, A. L., Bajaj, S. S., & Yang, C. J. (2021) · The Lancet Respiratory Medicine · doi:10.1016/s2213-2600(21)00210-1 · Cited by 68
Implementing Lung Cancer Screening in Europe: Taking a Systems Approach
Wait, S., Álvarez-Rosete, A., Osama, T., Bancroft, D., Cornelissen, R., Marušić, A., Garrido, P., Adamek, M., van Meerbeeck, J. P., Snoeckx, A., et al. (2022) · JTO Clinical and Research Reports · doi:10.1016/j.jtocrr.2022.100329 · Cited by 68
Robbins, H. A., Alcala, K., Swerdlow, A. J., Schoemaker, M. J., Wareham, N. J., Travis, R. C., Crosbie, P. A. J., Callister, M. E. J., Baldwin, D., Landy, R., et al. (2021) · British Journal of Cancer · doi:10.1038/s41416-021-01278-0 · Cited by 69
Hendrix, W., Rutten, M. J. C. M., Hendrix, N., van Ginneken, B., Schaefer‐Prokop, C. M., Scholten, E. T., Prokop, M., & Jacobs, C. (2023) · European Radiology · doi:10.1007/s00330-023-09826-3 · Cited by 67
Self-citationYeh, M. C.-H., Wang, Y.-H., Yang, H., Bai, K., Wang, H.-H., & Li, Y. (2021) · Journal of Medical Internet Research · doi:10.2196/26256 · Cited by 68
Westeel, V., Foucher, P., Scherpereel, A., Domas, J., Girard, P., Trédaniel, J., Wislez, M., Dumont, P., Quoix, É., Raffy, O., et al. (2022) · The Lancet Oncology · doi:10.1016/s1470-2045(22)00451-x · Cited by 68
Triphuridet, N., Zhang, S. S., Nagasaka, M., Gao, Y., Zhao, J. J., Syn, N. L. X., Hanaoka, T., Ou, S. I., & Shum, E. (2023) · Journal of Thoracic Oncology · doi:10.1016/j.jtho.2023.01.094 · Cited by 66
Potter, A. L., Xu, N. N., Senthil, P., Srinivasan, D. H., Lee, H., Gazelle, G. S., Chelala, L., Zheng, W., Fintelmann, F. J., Sequist, L. V. D., et al. (2024) · Journal of Clinical Oncology · doi:10.1200/jco.23.01780 · Cited by 66
Lam, A. C. L., Aggarwal, R., Cheung, S., Stewart, E., Darling, G. E., Lam, S. C., Xu, W., Liu, G., & Kavanagh, J. (2020) · Lung Cancer · doi:10.1016/j.lungcan.2020.05.013 · Cited by 64
Tækker, M., Kristjánsdóttir, B., Graumann, O., Laursen, C. B., & Pietersen, P. I. (2021) · Clinical Imaging · doi:10.1016/j.clinimag.2020.12.041 · Cited by 69
Zhang, Y., Jiang, B., Zhang, L., Greuter, M. J. W., de Bock, G. H., Zhang, H., & Xie, X. (2021) · Current Medical Imaging Formerly Current Medical Imaging Reviews · doi:10.2174/1573405617666210806125953 · Cited by 66
Bhamani, A., Creamer, A. W., Verghese, P., Prendecki, R., Horst, C., Tisi, S., Hall, H., Khaw, C. R., Mullin, M. L. L., McCabe, J., et al. (2025) · The Lancet Oncology · doi:10.1016/s1470-2045(25)00082-8 · Cited by 65
Contemporary issues in the implementation of lung cancer screening
Lam, S. C., & Tammemägi, M. C. (2021) · European Respiratory Review · doi:10.1183/16000617.0288-2020 · Cited by 65
Racial Differences in Adherence to Lung Cancer Screening Follow-up
Kunitomo, Y., Bade, B. C., Gunderson, C. G., Akgün, K. M., Brackett, A. L., Cain, H. C., Tanoue, L. T., & Bastian, L. A. (2021) · CHEST Journal · doi:10.1016/j.chest.2021.07.2172 · Cited by 64
Characteristics of Persons Screened for Lung Cancer in the United States
Silvestri, G. A., Goldman, L., Burleson, J., Gould, M. K., Kazerooni, E. A., Mazzone, P. J., Rivera, M. P., Doria-Rose, V. P., Rosenthal, L. S., Simanowith, M., et al. (2022) · Annals of Internal Medicine · doi:10.7326/m22-1325 · Cited by 64
Chen, H., Kim, A. W., Hsin, M. K. Y., Shrager, J. B., Prosper, A. E., Wahidi, M. M., Wigle, D. A., Wu, C. C., Huang, J. G., Yasufuku, K., et al. (2024) · Journal of Thoracic and Cardiovascular Surgery · doi:10.1016/j.jtcvs.2024.02.026 · Cited by 64
Multimorbidity in Patients with Chronic Obstructive Pulmonary Disease
Divo, M. J., & Celli, B. R. (2020) · Clinics in Chest Medicine · doi:10.1016/j.ccm.2020.06.002 · Cited by 70
Metadata
- Authors
- de Koning, H. J., van der Aalst, C. M., de Jong, P. A., Scholten, E. T., Nackaerts, K., Heuvelmans, M. A., Lammers, J.-W. J., Weenink, C., Yousaf-Khan, U., Horeweg, N., van ’t Westeinde, S., Prokop, M., Mali, W. P., Mohamed Hoesein, F. A. A., van Ooijen, P. M. A., Aerts, J. G. J. V., den Bakker, M. A., Thunnissen, E., Verschakelen, J., Vliegenthart, R., Walter, J. E., ten Haaf, K., Groen, H. J. M., & Oudkerk, M.
- Affiliations
- From the Departments of Public Health (H.J.K., C.M.A., U.Y.-K., K.H.) and Pulmonology (J.G.J.V.A.), Erasmus MC–University Medical Center Rotterdam, and the Departments of Pulmonology (S.W.) and Pathology (M.A.B.), Maasstad Hospital, Rotterdam, the Departments of Radiology (P.A.J., W.P.M., F.A.A.M.H.) and Pulmonology (J.-W.J.L.), University Medical Center Utrecht, Utrecht, the Departments of Radiology (E.T.S.) and Pulmonology (C.W.), Spaarne Gasthuis, Haarlem, the Department of Radiation Oncology,...
- Erasmus MC (NL)
- Leiden University Medical Center (NL)
- University Medical Center Groningen (NL)
- ORCID
- Venue
- New England Journal of Medicine
- Publisher
- Massachusetts Medical Society
- Published
- 2020-02-06
- Volume
- 382
- Issue
- 6
- Pages
- 503-513
- ISSN
- 0028-4793 (ISSN-L)
- 1533-4406
- OpenAlex
- W3003415550
- Cited by
- 3,624
- References
- 76
- Citations by year
- 2026: 538 · 2025: 626 · 2024: 568 · 2023: 588 · 2022: 532 · 2021: 492 · 2020: 275
- FWCI
- 266.35
- Type
- journal article
- Language
- en
- Open access
- hybrid
- doi.org
- Licence
- Locations
- New England Journal of Medicine (publishedVersion, other-oa)
- PubMed (publishedVersion)
- Pure Amsterdam UMC (publishedVersion, cc-by)
- EUR Research Repository (Erasmus University Rotterdam) (publishedVersion)
- University of Groningen research database (University of Groningen / Centre for Information Technology) (publishedVersion, other-oa)
- Leiden Repository (Leiden University) (submittedVersion)
- Lirias (submittedVersion, other-oa)
- Radboud Repository (Radboud University) (submittedVersion)
- EUR Research Repository (Erasmus University Rotterdam) (submittedVersion)
- Data Archiving and Networked Services (DANS) (submittedVersion, other-oa)
- Utrecht University Repository (Utrecht University) (submittedVersion, other-oa)
- Amsterdam UMC (VU Amsterdam) - Institutional Repository (submittedVersion, other-oa)
- Radboud Repository (Radboud University) (submittedVersion, other-oa)
- University of Groningen research database (University of Groningen / Centre for Information Technology) (submittedVersion)
- University of Groningen research database (University of Groningen / Centre for Information Technology) (submittedVersion, other-oa)
- Utrecht University Repository (Utrecht University) (submittedVersion)
- Funders
- LOGO Leuven
- The Netherlands Organization of Health Research and Development
- Dutch Cancer Society
- Health Insurance Innovation Foundation
- Siemens Germany
- Roche Diagnostics
- G.Ph. Verhagen Stichting
- Rotterdam Oncologic Study (ROTS) group
- Erasmus Trust Fund
- Stichting Tegen Kanker
- Vlaamse Liga Tegen Kanker
- Topics
- Health Sciences › Medicine › Pulmonary and Respiratory Medicine › Lung Cancer Diagnosis and Treatment
- Health Sciences › Medicine › Oncology › Global Cancer Incidence and Screening
- Health Sciences › Medicine › Pulmonary and Respiratory Medicine › Occupational and environmental lung diseases
- Keywords
- lung cancer screening, low-dose CT, lung cancer mortality, smoking, men, women, screening adherence, lung cancer incidence, NELSON trial, cancer mortality reduction, follow-up procedures, cancer registry linkage, Netherlands, vulnerable populations, cost-effectiveness of screening
- MeSH terms
- Medical Overuse, Aged, Belgium, False Positive Reactions, Female, Humans, Lung Neoplasms, Male, Middle Aged, Netherlands, Registries, Sex Factors, Smoking, Incidence, Cone-Beam Computed Tomography, Early Detection of Cancer
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
