Adagrasib with or without Cetuximab in Colorectal Cancer with Mutated KRAS G12C
Yaeger, Rona, Weiss, Jared, Pelster, Meredith S., Spira, Alexander I., Barve, Minal, Ou, Sai-Hong I., Leal, Ticiana A., Bekaii-Saab, Tanios S. +7 more·2023·New England Journal of Medicine
Cited by (114)
Items 101–114 of 114
- Targeting BCL2 with Venetoclax Enhances the Efficacy of the
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G12D Inhibitor MRTX1133 in Pancreatic CancerBecker, Jeffrey H., Metropulos, Anastasia E., Spaulding, Christina, Marinelarena, Alejandra M., Shields, Mario A., Principe, Daniel R., Pham, Thao D., Munshi, Hidayatullah G. · 2024 · Cancer Research
- Mechanisms of KRAS inhibitor resistance in KRAS-mutant colorectal cancer harboring Her2 amplification and aberrant KRAS localizationMaruyama, Kohei, Shimizu, Yuki, Nomura, Yumi, Oh-hara, Tomoko, Takahashi, Yuki, Nagayama, Satoshi, Fujita, Naoya, Katayama, Ryohei · 2025 · npj Precision Oncology
- High tumor mutation burden (TMB) in microsatellite stable (MSS) colorectal cancers: Diverse molecular associations point to variable pathophysiologyVoutsadakis, Ioannis A. · 2023 · Cancer Treatment and Research Communications
- Ready, Set, Go: Setting Off on the Mission to Target
<i>KRAS</i>
in Colorectal CancerPellatt, Andrew J., Bhamidipati, Deepak, Subbiah, Vivek · 2024 · JCO Oncology Practice
- Exploring and bypassing resistance to targeted therapies in colorectal cancerFavier, Solène, Xiong, Wei, Chalabi-Dchar, Mounira, Chettab, Kamel, Piercey, Oliver, Wu, Ting, Fenouil, Tanguy, Albaret, Marie-Alexandra, Jordheim, Lars Petter, Diaz, Jean-Jacques et al. · 2025 · Biomedicine & Pharmacotherapy
- KRAS, a New Target for Precision Medicine in Colorectal Cancer?Boilève, Alice, Smolenschi, Cristina, Lambert, Aurélien, Boige, Valérie, Delaye, Matthieu, Camilleri, Géraldine M., Tarabay, Anthony, Valéry, Marine, Fuerea, Alina, Pudlarz, Thomas et al. · 2024 · Cancers
- RAS Mutations in Advanced Colorectal Cancer: Mechanisms, Clinical Implications, and Novel Therapeutic ApproachesSütcüoğlu, Osman, Yıldırım, Hasan Çağrı, Almuradova, Elvina, Günenç, Damla, Yalçın, Şuayib · 2025 · Medicina
- Differential Response and Resistance to KRAS-Targeted TherapyLiu, Zhaojin, Lenz, Heinz‐Josef, Yu, Jian, Zhang, Lin · 2025 · Molecular Carcinogenesis
- EGFR Signaling in Colorectal Cancer: Novel Therapeutic Strategies, Predictive Biomarkers, and Counteracting Treatment ResistanceAbbas, Noura, Mourad, Mohamad, Smaily, Hiba, Al Mahmasani, Layal, Shamseddine, Ali · 2026 · International Journal of Molecular Sciences
- Glecirasib with or without cetuximab in previously treated locally advanced or metastatic colorectal cancer with KRASG12C mutation (JAB-21822-1002 and JAB-21822-1007): two open-label, non-randomised phase 1/2 trialsLi, Jian, Wang, Zhenghang, Huang, Jing, Ba, Yi, Cao, Baoshan, Luo, Suxia, Li, Wenhua, Bai, Chunmei, Song, Zhengbo, Xiong, Jianping et al. · 2026 · The Lancet Gastroenterology & Hepatology
- Characterization of KRASG12C inhibitor olomorasib single-agent and combination with activity in KRASG12C-mutant modelsPeng, Shengbin, Zhang, Youyan, Lin, Xi, Si, Chong, Van Horn, Robert Daniel, Dempsey, Jack A., Goetz, Eva, Evans, Robert J., Farber, Andrew, Vandekopple, Matthew J. et al. · 2026 · Nature Communications
- Precision Targeting of KRAS-Mutant Cancers: Beyond G12C Toward G12D and Pan-RAS Therapeutic StrategiesKano, Yoshihito · 2026 · International Journal of Molecular Sciences
- Emerging Therapeutic Strategies for Non-G12C KRAS Mutations in Colorectal Cancer: Focusing on G12D and G12VSagawa, Tamotsu, Hirakawa, Masahiro, Nagashima, Hiroyuki, Fujikawa, Koshi · 2026 · Journal of Gastrointestinal Cancer
- Adaptive Feedback Signaling Through the FAK/SRC Pathway Promotes KRAS G12C Inhibitor ResistanceUdagawa, Hibiki, Shibata, Yuji, Nilsson, Monique B., Nishii, Kazuya, Robichaux, Jacqulyne P., Galan-Cobo, Ana, He, Junqin, Poteete, Alissa, Qian, Yu, Molkentine, David et al. · 2026 · Journal of Thoracic Oncology