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Bacterial Meningitis — A View of the Past 90 Years
Abstract
The history of community-acquired bacterial meningitis arguably represents the best example of the salutary effect of the introduction of antimicrobial agents. Before the use of specific antiserums, the outlook for patients with bacterial meningitis was dismal (see Figure). In the 1920s, 77 of 78 children at Boston Children's Hospital who had Haemophilus influenzae meningitis died. The prognosis for untreated pneumococcal meningitis was equally bleak: of 300 patients, all died. In the first decade of the 20th century, untreated meningococcal meningitis was associated with a mortality rate of 75 to 80 percent.In 1913, Simon Flexner was the first to report . . .
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Cites
Clinical features and prognostic factors in adults with bacterial meningitis
van de Beek, D., de Gans, J., Spanjaard, L., Weisfelt, M., Reitsma, J. B., & Vermeulen, M. (2004) · New England Journal of Medicine · doi:10.1056/nejmoa040845 · Cited by 1,639
Cited by
Castelblanco, R. L., Lee, M., & Hasbun, R. (2014) · The Lancet Infectious Diseases · doi:10.1016/s1473-3099(14)70805-9 · Cited by 245
Jayachandran, S., Lleras-Muney, A., & Smith, K. V. (2010) · American Economic Journal: Applied Economics · doi:10.1257/app.2.2.118 · Cited by 230
Acute Bacterial Meningitis in Infants and Children: Epidemiology and Management
Agrawal, S., & Nadel, S. (2011) · Pediatric Drugs · doi:10.2165/11593340-000000000-00000 · Cited by 99
Spontaneous gram-negative bacillary meningitis in adult patients: characteristics and outcome
Pomar, V., Benito, N., López-Contreras, J., Coll, P., Gurguí, M., & Domingo, P. (2013) · BMC Infectious Diseases · doi:10.1186/1471-2334-13-451 · Cited by 68
Bodilsen, J., Larsen, L., Brandt, C. T., Wiese, L., Hansen, B. R., Andersen, C. Ø., Lüttichau, H. R., Helweg-Larsen, J., Storgaard, M., & Nielsen, H. (2021) · Clinical Epidemiology · doi:10.2147/clep.s326461 · Cited by 33
Metadata
- Authors
- Swartz, M. N.
- Venue
- New England Journal of Medicine
- Publisher
- Massachusetts Medical Society
- Published
- 2004-10-28
- Volume
- 351
- Issue
- 18
- Pages
- 1826-1828
- ISSN
- 0028-4793 (ISSN-L)
- 1533-4406
- OpenAlex
- W1980010510
- Cited by
- 211
- References
- 1
- FWCI
- 8.87
- Type
- journal article
- Language
- en
- Open access
- closed
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.