The DOI matches its Crossref record; 59 of the 60 references it cites were found in a registry or an index, and 1 are not checked yet.
Managing hyperkalemia caused by inhibitors of the renin-angiotensin-aldosterone system
Abstract
Hyperkalemia can develop as a result of treatment with angiotensin-converting–enzyme inhibitors or angiotensin-receptor blockers. This side effect is most common in patients with risk factors such as diabetes mellitus, heart failure, chronic kidney disease, or advanced age. This review explains the pathophysiology and offers clinical guidance for management.
Overview
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
In the citing paper
“Risk factors for the development of hyperkalemia with the use of drugs that inhibit the RAS included CKD, diabetes, decompensated congestive heart failure, volume depletion, advanced age, and use of concomitant medications that interfere with kidney potassium excretion. 71”
From KDIGO 2022 Clinical Practice Guideline for Diabetes Management in Chronic Kidney Disease (2022) · cites this paper as [71]
Citations
Cites
1 retracted
Nakao, N., Yoshimura, A., Morita, H., Takada, M., Kayano, T., & Ideura, T. (2003) · The Lancet · doi:10.1016/s0140-6736(03)12229-5 · Cited by 947
RetractedLevey, A. S., Bosch, J. P., Lewis, J. B., Greene, T., Rogers, N., Roth, D., & for the Modification of Diet in Renal Disease Study Group* (1999) · Annals of Internal Medicine · doi:10.7326/0003-4819-130-6-199903160-00002 · Cited by 15,079
The Effect of Spironolactone on Morbidity and Mortality in Patients with Severe Heart Failure
Pitt, B., Zannad, F., Remme, W. J., Cody, R., Castaigne, A., Perez, A., Palensky, J., & Wittes, J. (1999) · New England Journal of Medicine · doi:10.1056/nejm199909023411001 · Cited by 9,214
(2000) · New England Journal of Medicine · doi:10.1056/nejm200001203420301 · Cited by 8,663
Brenner, B. M., Cooper, M. E., de Zeeuw, D., Keane, W. F., Mitch, W. E., Parving, H.-H., Remuzzi, G., Snapinn, S. M., Zhang, Z., & Shahinfar, S. (2001) · New England Journal of Medicine · doi:10.1056/nejmoa011161 · Cited by 7,493
Lewis, E. J., Hunsicker, L. G., Clarke, W. R., Berl, T., Pohl, M. A., Lewis, J. B., Ritz, E., Atkins, R. C., Rohde, R., & Raz, I. (2001) · New England Journal of Medicine · doi:10.1056/nejmoa011303 · Cited by 5,987
Pitt, B., Remme, W., Zannad, F., Neaton, J., Martinez, F., Roniker, B., Bittman, R., Hurley, S., Kleiman, J., & Gatlin, M. (2003) · New England Journal of Medicine · doi:10.1056/nejmoa030207 · Cited by 4,941
A Randomized Trial of the Angiotensin-Receptor Blocker Valsartan in Chronic Heart Failure
Cohn, J. N., & Tognoni, G. (2001) · New England Journal of Medicine · doi:10.1056/nejmoa010713 · Cited by 3,108
The Effect of Spironolactone on Morbidity and Mortality in Patients with Severe Heart Failure
Pitt, B., Zannad, F. M., Remme, W. J., Cody, R. J., Castaigne, A., Pérez, A. J. P., Palensky, J., & Wittes, J. T. (2000) · Survey of Anesthesiology · doi:10.1097/00132586-200006000-00059 · Cited by 2,927
McMurray, J. J., Östergren, J., Swedberg, K., Granger, C. B., Held, P., Michelson, E. L., Olofsson, B., Yusuf, S., & Pfeffer, M. A. (2003) · The Lancet · doi:10.1016/s0140-6736(03)14283-3 · Cited by 2,604
Research works printed but not linked: 4
- Young DB, 1984, Am J Physiol, 247, E328
- Palmer BF, 1995, J Investig Med, 43, 516
- 1995, MMWR Morb Mortal Wkly Rep, 44, 853
- Dardik A, 2000, South Med J, 93, 511, 10.1097/00007611-200093050-00016 · DOI
Cited by
Sorted by citations
KDIGO 2020 Clinical practice guideline for diabetes management in chronic kidney disease
de Boer, I. H., Caramori, M. L., Chan, J. C. N., Heerspink, H. J. L., Hurst, C., Khunti, K., Liew, A., Michos, E. D., Navaneethan, S. D., Olowu, W. A., et al. (2020) · Kidney International · doi:10.1016/j.kint.2020.06.019 · Cited by 1,399
KDIGO 2022 Clinical Practice Guideline for Diabetes Management in Chronic Kidney Disease
Rossing, P., Caramori, M. L., Chan, J. C. N., Heerspink, H. J. L., Hurst, C., Khunti, K., Liew, A., Michos, E. D., Navaneethan, S. D., Olowu, W. A., et al. (2022) · Kidney International · doi:10.1016/j.kint.2022.06.008 · Cited by 1,373
Rodbard, H. W., Blonde, L., Ss, B., Brett, E. M., Cobin, R. H., Handelsman, Y., Hellman, R., Jellinger, P. S., Jovanovic, L. G., Levy, P., et al. (2007) · Endocrine Practice · doi:10.4158/ep.13.s1.1 · Cited by 695
Patiromer in Patients with Kidney Disease and Hyperkalemia Receiving RAAS Inhibitors
Weir, M. R., Bakris, G. L., Bushinsky, D. A., Mayo, M. R., Garza, D., Stasiv, Y., Wittes, J. T., Christ‐Schmidt, H., Berman, L., & Pitt, B. (2014) · New England Journal of Medicine · doi:10.1056/nejmoa1410853 · Cited by 683
The Frequency of Hyperkalemia and Its Significance in Chronic Kidney Disease
Einhorn, L. M., Zhan, M., Hsu, V. D., Walker, L. D., Moen, M. F., Seliger, S. L., Weir, M. R., & Fink, J. C. (2009) · Archives of Internal Medicine · doi:10.1001/archinternmed.2009.132 · Cited by 655
Dunlay, S. M., Givertz, M. M., Aguilar, D., Allen, L. A., Chan, M., Desai, A. S., Deswal, A., Dickson, V. V., Kosiborod, M. N., Lekavich, C. L., et al. (2019) · Circulation · doi:10.1161/cir.0000000000000691 · Cited by 639
Clase, C. M., Carrero, J.-J., Ellison, D. H., Grams, M. E., Hemmelgarn, B. R., Jardine, M. J., Kovesdy, C. P., Kline, G. A., Lindner, G., Obrador, G. T., et al. (2020) · Kidney International · doi:10.1016/j.kint.2019.09.018 · Cited by 498
Self-citationBakris, G. L., Pitt, B., Weir, M. R., Freeman, M. W., Mayo, M. R., Garza, D., Stasiv, Y., Zawadzki, R., Berman, L., & Bushinsky, D. A. (2015) · JAMA · doi:10.1001/jama.2015.7446 · Cited by 441
Collins, A. J., Pitt, B., Reaven, N. L., Funk, S. E., McGaughey, K. J., Wilson, D. J., & Bushinsky, D. A. (2017) · American Journal of Nephrology · doi:10.1159/000479802 · Cited by 411
Diabetes mellitus and electrolyte disorders
Liamis, G. L. (2014) · World Journal of Clinical Cases · doi:10.12998/wjcc.v2.i10.488 · Cited by 406
Kovesdy, C. P., Matsushita, K., Sang, Y., Brunskill, N. J., Carrero, J. J., Chodick, G., Hasegawa, T., Heerspink, H. J. L., Hirayama, A., Landman, G. W. D., et al. (2018) · European Heart Journal · doi:10.1093/eurheartj/ehy100 · Cited by 358
Physiology and pathophysiology of potassium homeostasis
Palmer, B. F., & Clegg, D. J. (2016) · AJP Advances in Physiology Education · doi:10.1152/advan.00121.2016 · Cited by 286
Self-citationCirrhosis and its complications: Evidence based treatment
Nusrat, S. (2014) · World Journal of Gastroenterology · doi:10.3748/wjg.v20.i18.5442 · Cited by 297
Potentially Harmful Drug–Drug Interactions in the Elderly: A Review
Hines, L. E., & Murphy, J. E. (2011) · The American Journal of Geriatric Pharmacotherapy · doi:10.1016/j.amjopharm.2011.10.004 · Cited by 275
Lee, H., Shin, J., Kim, G., Park, S., Ihm, S., Kim, H. C., Kim, K., Kim, J. H., Lee, J. H., Park, J., et al. (2019) · Clinical Hypertension · doi:10.1186/s40885-019-0124-x · Cited by 274
Management of severe hyperkalemia
Weisberg, L. S. (2008) · Critical Care Medicine · doi:10.1097/ccm.0b013e31818f222b · Cited by 268
Use of Aldosterone Antagonists in Heart Failure
Albert, N. M. (2009) · JAMA · doi:10.1001/jama.2009.1493 · Cited by 262
Rossignol, P., Dobre, D., McMurray, J. J. V., Swedberg, K. B., Krum, H., van Veldhuisen, D. J., Shi, H. H., Messig, M., Vincent, J., Girerd, N., et al. (2013) · Circulation Heart Failure · doi:10.1161/circheartfailure.113.000792 · Cited by 261
Electrolyte and Acid–Base Disturbances in Patients with Diabetes Mellitus
Palmer, B. F., & Clegg, D. J. (2015) · New England Journal of Medicine · doi:10.1056/nejmra1503102 · Cited by 258
Self-citationButler, J., Anker, S. D., Lund, L. H., Coats, A. J. S., Filippatos, G. S., Siddiqi, T. J., Friede, T., Fabien, V., Kosiborod, M., Metra, M., et al. (2022) · European Heart Journal · doi:10.1093/eurheartj/ehac401 · Cited by 238
Drug dosing adjustments in patients with chronic kidney disease.
Munar, M. Y., & Singh, H. (2007) · PubMed · Cited by 231
Desai, A. S., Vardeny, O., Claggett, B. L., McMurray, J. J. V., Packer, M., Swedberg, K. B., Rouleau, J. L., Zile, M. R., Lefkowitz, M. P., Shi, V. C., et al. (2016) · JAMA Cardiology · doi:10.1001/jamacardio.2016.4733 · Cited by 226
Intensive Blood-Pressure Control in Patients with Type 2 Diabetes
Bi, Y., Li, M., Liu, Y., Li, T., Lu, J., Duan, P., Xu, F., Dong, Q., Wang, A., Wang, T., et al. (2025) · New England Journal of Medicine · doi:10.1056/nejmoa2412006 · Cited by 224
Renin Angiotensin System Blockade in Kidney Transplantation: A Systematic Review of the Evidence
Hiremath, S. S., Fergusson, D. A., Doucette, S. P., Mulay, A. V., & Knoll, G. A. (2007) · American Journal of Transplantation · doi:10.1111/j.1600-6143.2007.01928.x · Cited by 210
Rosano, G. M. C., Tamargo, J. L., Kjeldsen, K. P., Lainščak, M., Agewall, S., Anker, S. D., Ceconi, C., Coats, A. J. S., Drexel, H., Filippatos, G. S., et al. (2018) · European Heart Journal - Cardiovascular Pharmacotherapy · doi:10.1093/ehjcvp/pvy015 · Cited by 204
Effects of dapagliflozin in stage 4 chronic kidney disease
Chertow, G. M., Vart, P., Jongs, N., Toto, R. D., Gorriz, J. L., Hou, F. F., McMurray, J. J. V., Correa-Rotter, R., Rossing, P., Sjöström, C. D., et al. (2021) · Journal of the American Society of Nephrology · doi:10.1681/asn.2021020167 · Cited by 201
Management of hyperkalaemia in chronic kidney disease
Kovesdy, C. P. (2014) · Nature Reviews Nephrology · doi:10.1038/nrneph.2014.168 · Cited by 201
Associations of serum potassium levels with mortality in chronic heart failure patients
Aldahl, M., Jensen, A.-S. C., Davidsen, L., Eriksen, M. A., Hansen, S. M., Nielsen, B. J., Krogager, M. L., Køber, L., Torp-Pedersen, C. T., & Søgaard, P. (2017) · European Heart Journal · doi:10.1093/eurheartj/ehx460 · Cited by 200
Abnormalities of Potassium in Heart Failure
Ferreira, J. P., Butler, J., Rossignol, P., Pitt, B., Anker, S. D., Kosiborod, M., Lund, L. H., Bakris, G. L., Weir, M. R., & Zannad, F. M. (2020) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2020.04.021 · Cited by 208
Clinical Management of Hyperkalemia
Palmer, B. F., Carrero, J. J., Clegg, D. J., Colbert, G. B., Emmett, M., Fishbane, S. N., Hain, D. J., Lerma, E. V., Onuigbo, M. A. C., Rastogi, A., et al. (2020) · Mayo Clinic Proceedings · doi:10.1016/j.mayocp.2020.06.014 · Cited by 204
Self-citationRaebel, M. A. (2011) · Cardiovascular Therapeutics · doi:10.1111/j.1755-5922.2010.00258.x · Cited by 190
Sarafidis, P. A., Blacklock, R. M., Wood, E., Rumjon, A., Simmonds, S., Fletcher-Rogers, J., Ariyanayagam, R., Al-Yassin, A., Sharpe, C. C., & Vinen, K. (2012) · Clinical Journal of the American Society of Nephrology · doi:10.2215/cjn.01150112 · Cited by 187
Saha, C., Eckert, G., Ambrosius, W., Chun, T., Wagner, M. A., Zhao, Q.-Q., & Pratt, J. (2005) · HYPERTENSION · doi:10.1161/01.hyp.0000179582.42830.1d · Cited by 180
Renal Failure Associated with Cancer and Its Treatment
Humphreys, B. D., Soiffer, R. J., & Magee, C. (2004) · Journal of the American Society of Nephrology · doi:10.1681/asn.2004100843 · Cited by 177
Incidence and Predictors of Hyperkalemia in Patients With Heart Failure
Desai, A. S., Swedberg, K., McMurray, J. J. V., Granger, C. B., Yusuf, S., Young, J. B., Dunlap, M. E., Solomon, S. D., Hainer, J. W., Olofsson, B., et al. (2007) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2007.07.067 · Cited by 170
Hwang, Y. J., Shariff, S. Z., Gandhi, S., Wald, R., Clark, E. G., Fleet, J. L., & Garg, A. X. (2012) · BMJ Open · doi:10.1136/bmjopen-2012-001821 · Cited by 167
Ezekowitz, J. A., & McAlister, F. A. (2008) · European Heart Journal · doi:10.1093/eurheartj/ehn543 · Cited by 167
Prediction and Management of Hyperkalemia Across the Spectrum of Chronic Kidney Disease
Lazich, I., & Bakris, G. L. (2014) · Seminars in Nephrology · doi:10.1016/j.semnephrol.2014.04.008 · Cited by 164
Serum Potassium, End-Stage Renal Disease and Mortality in Chronic Kidney Disease
Nakhoul, G., Huang, H., Arrigain, S., Jolly, S. E., Schold, J. D., Nally, J. V., & Navaneethan, S. D. (2015) · American Journal of Nephrology · doi:10.1159/000437151 · Cited by 168
Heart Failure in Patients with Chronic Kidney Disease: A Systematic Integrative Review
Segall, L., Nistor, I., & Covic, A. C. (2014) · BioMed Research International · doi:10.1155/2014/937398 · Cited by 164
Pitt, B., Bakris, G. L., Bushinsky, D. A., Garza, D., Mayo, M. R., Stasiv, Y., Christ‐Schmidt, H., Berman, L., & Weir, M. R. (2015) · European Journal of Heart Failure · doi:10.1002/ejhf.402 · Cited by 159
Salem, C. B., Badreddine, A., Fathallah, N., Slim, R., & Hmouda, H. (2014) · Drug Safety · doi:10.1007/s40264-014-0196-1 · Cited by 151
Dunlay, S. M., Givertz, M. M., Aguilar, D., Allen, L. A., Chan, M., Desai, A. S., Deswal, A., Dickson, V. V., Kosiborod, M. N., Lekavich, C. L., et al. (2019) · Journal of Cardiac Failure · doi:10.1016/j.cardfail.2019.05.007 · Cited by 145
Khanagavi, J., Gupta, T., Aronow, W. S., Shah, T. M., Garg, J., Ahn, C. W., Sule, S. S., & Peterson, S. (2014) · Archives of Medical Science · doi:10.5114/aoms.2014.42577 · Cited by 144
Treatment of hyperkalemia: something old, something new
Sterns, R. H., Grieff, M., & Bernstein, P. L. (2016) · Kidney International · doi:10.1016/j.kint.2015.11.018 · Cited by 143
Management of Hyperkalemia: An Update for the Internist
Kovesdy, C. P. (2015) · The American Journal of Medicine · doi:10.1016/j.amjmed.2015.05.040 · Cited by 140
Antoniou, T. (2010) · Archives of Internal Medicine · doi:10.1001/archinternmed.2010.142 · Cited by 140
Lakhdar, R., Al-Mallah, M. H., & Lanfear, D. E. (2008) · Journal of Cardiac Failure · doi:10.1016/j.cardfail.2007.11.008 · Cited by 129
Karim, N., Jia, Z., Zheng, X., Cui, S., & Chen, W. (2018) · Trends in Food Science & Technology · doi:10.1016/j.tifs.2018.06.012 · Cited by 129
Fried, L. F., Duckworth, W. C., Zhang, J. H., O’Connor, T., Brophy, M. T., Emanuele, N., Huang, G. D., McCullough, P. A., Palevsky, P. M., Seliger, S. L., et al. (2008) · Clinical Journal of the American Society of Nephrology · doi:10.2215/cjn.03350708 · Cited by 128
Diagnosis and treatment of hyperkalemia
Palmer, B. F., & Clegg, D. J. (2017) · Cleveland Clinic Journal of Medicine · doi:10.3949/ccjm.84a.17056 · Cited by 127
Self-citationRossignol, P., Legrand, M. M., Kosiborod, M., Hollenberg, S. M., Peacock, W. F., Emmett, M., Epstein, M., Kovesdy, C. P., Yılmaz, M. B., Stough, W. G., et al. (2016) · Pharmacological Research · doi:10.1016/j.phrs.2016.09.039 · Cited by 126
Sarwar, C. M. S., Papadimitriou, L., Pitt, B., Piña, I. L., Zannad, F. M., Anker, S. D., Gheorghiade, M., & Butler, J. (2016) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2016.06.060 · Cited by 117
Meaney, C. J., Beccari, M. V., Yang, Y., & Zhao, J. (2017) · Pharmacotherapy The Journal of Human Pharmacology and Drug Therapy · doi:10.1002/phar.1906 · Cited by 115
Renal Tubular Acidosis and Management Strategies: A Narrative Review
Palmer, B. F., Kelepouris, E., & Clegg, D. J. (2020) · Advances in Therapy · doi:10.1007/s12325-020-01587-5 · Cited by 115
Self-citationUpdates in hyperkalemia: Outcomes and therapeutic strategies
Kovesdy, C. P. (2016) · Reviews in Endocrine and Metabolic Disorders · doi:10.1007/s11154-016-9384-x · Cited by 111
Bushinsky, D. A., Williams, G. H., Pitt, B., Weir, M. R., Freeman, M. W., Garza, D., Stasiv, Y., Li, E., Berman, L., & Bakris, G. L. (2015) · Kidney International · doi:10.1038/ki.2015.270 · Cited by 110
Chronic Kidney Disease in Diabetes
McFarlane, P. A., Cherney, D. Z. I., Gilbert, R. E., & Senior, P. A. (2018) · Canadian Journal of Diabetes · doi:10.1016/j.jcjd.2017.11.004 · Cited by 112
Chronic Kidney Disease in Diabetes
McFarlane, P. A., Gilbert, R. E., MacCallum, L., & Senior, P. A. (2013) · Canadian Journal of Diabetes · doi:10.1016/j.jcjd.2013.01.037 · Cited by 102
Fralick, M., Macdonald, E. M., Gomes, T., Antoniou, T., Hollands, S., Mamdani, M. M., & Juurlink, D. N. (2014) · BMJ · doi:10.1136/bmj.g6196 · Cited by 104
Aydogan, A., Coady, D. J., Kim, S. K., Akar, A., Bielawski, C. W., Márquez, M., & Sessler, J. L. (2008) · Angewandte Chemie International Edition · doi:10.1002/anie.200803970 · Cited by 102
Potassium Metabolism and Management in Patients with CKD
Yamada, S., & Inaba, M. (2021) · Nutrients · doi:10.3390/nu13061751 · Cited by 101
Kovesdy, C. P., Appel, L. J., Grams, M. E., Gutekunst, L., McCullough, P. A., Palmer, B. F., Pitt, B., Sica, D. A., & Townsend, R. R. (2017) · Journal of the American Society of Hypertension · doi:10.1016/j.jash.2017.09.011 · Cited by 103
Self-citationMiao, Y., Dobre, D., Heerspink, H. J. L., Brenner, B. M., Cooper, M. E., Parving, H.-H., Shahinfar, S., Grobbee, D. E., & de Zeeuw, D. (2010) · Diabetologia · doi:10.1007/s00125-010-1922-6 · Cited by 100
Thomsen, R. W., Nicolaisen, S. K., Hasvold, P., Sanchez, R. G., Pedersen, L. H., Adelborg, K., Egstrup, K., Egfjord, M., & Sørensen, H. T. (2017) · Nephrology Dialysis Transplantation · doi:10.1093/ndt/gfx312 · Cited by 96
Kovesdy, C. P., Appel, L. J., Grams, M. E., Gutekunst, L., McCullough, P. A., Palmer, B. F., Pitt, B., Sica, D. A., & Townsend, R. R. (2017) · American Journal of Kidney Diseases · doi:10.1053/j.ajkd.2017.09.003 · Cited by 95
Self-citationHyperkalemia in Real-World Patients Under Continuous Medical Care in Japan
Kashihara, N., Kohsaka, S., Kanda, E., Okami, S., & Yajima, T. (2019) · Kidney International Reports · doi:10.1016/j.ekir.2019.05.018 · Cited by 94
Antonio Vukusich, C., Sonia Kunstmann, F., Varela, C., Daniela Gainza, K., Bravo, S., Sepúlveda, D., Cavada, G., Michea, L., & Marusic, E. T. (2010) · Clinical Journal of the American Society of Nephrology · doi:10.2215/cjn.09421209 · Cited by 94
Empagliflozin and serum potassium in heart failure: an analysis from EMPEROR-Pooled
Ferreira, J. P., Zannad, F. M., Butler, J., Filipattos, G., Ritter, I., Schueler, E., Kraus, B. J., Pocock, S., Anker, S. D., & Packer, M. (2022) · European Heart Journal · doi:10.1093/eurheartj/ehac306 · Cited by 92
de Sousa, A. G. P., Cabral, J. V., El-Feghaly, W. B., sousa, L. K. L., & Nunes, A. B. (2016) · World Journal of Diabetes · doi:10.4239/wjd.v7.i5.101 · Cited by 93
Raebel, M. A., McClure, D. L., Simon, S. R., Chan, K. A., Feldstein, A. C., Andrade, S. E., Lafata, J. E., Roblin, D. W., Davis, R. L., Gunter, M. J., et al. (2006) · Pharmacoepidemiology and Drug Safety · doi:10.1002/pds.1217 · Cited by 88
Vukadinović, D., Lavall, D., Vukadinović, A. N., Pitt, B., Wagenpfeil, S., & Böhm, M. (2017) · American Heart Journal · doi:10.1016/j.ahj.2017.03.011 · Cited by 90
Banerjee, D., Winocour, P. H., Chowdhury, T. A., De, P., Wahba, M. M., Montero, R., Fogarty, D. G., Frankel, A., Karalliedde, J. J., Mark, P. B., et al. (2022) · BMC Nephrology · doi:10.1186/s12882-021-02587-5 · Cited by 92
A Physiologic-Based Approach to the Evaluation of a Patient With Hypokalemia
Palmer, B. F. (2010) · American Journal of Kidney Diseases · doi:10.1053/j.ajkd.2010.07.010 · Cited by 86
Self-citationDavidovich, E., Davidovits, M., Eidelman, E., Schwarz, Z., & Bimstein, E. (2005) · PubMed · Cited by 85
Singer, A. J., Thode, H. C., & Peacock, W. F. (2017) · Clinical and Experimental Emergency Medicine · doi:10.15441/ceem.16.194 · Cited by 83
Metabolic Complications Associated With Use of Diuretics
Palmer, B. F. (2011) · Seminars in Nephrology · doi:10.1016/j.semnephrol.2011.09.009 · Cited by 83
Self-citationBamberg, K., Johansson, U., Edman, K., William‐Olsson, L., Myhre, S., Gunnarsson, A., Geschwindner, S., Aagaard, A., Granqvist, A., Jaisser, F., et al. (2018) · PLoS ONE · doi:10.1371/journal.pone.0193380 · Cited by 82
Proteinuria as a Therapeutic Target in Patients with Chronic Kidney Disease
Palmer, B. F. (2007) · American Journal of Nephrology · doi:10.1159/000101958 · Cited by 82
Self-citationThomsen, R. W., Nicolaisen, S. K., Hasvold, P., García‐Sánchez, R., Pedersen, L. H., Adelborg, K., Egfjord, M., Egstrup, K., & Sørensen, H. T. (2018) · Journal of the American Heart Association · doi:10.1161/jaha.118.008912 · Cited by 81
New Potassium Binders for the Treatment of Hyperkalemia
Pitt, B., & Bakris, G. L. (2015) · Hypertension · doi:10.1161/hypertensionaha.115.04889 · Cited by 79
Humphrey, T. J. L., Davids, M. R., Chothia, M., Pecoits‐Filho, R., Pollock, C. A., & James, G. (2021) · Clinical Kidney Journal · doi:10.1093/ckj/sfab243 · Cited by 80
Ellison, D. H., Terker, A. S., & Gamba, G. (2015) · Journal of the American Society of Nephrology · doi:10.1681/asn.2015070751 · Cited by 76
Diabetes and Drug-Associated Hyperkalemia: Effect of Potassium Monitoring
Raebel, M. A., Ross, C. A., Xu, S., Roblin, D. W., Cheetham, C., Blanchette, C. M., Saylor, G., & Smith, D. H. (2010) · Journal of General Internal Medicine · doi:10.1007/s11606-009-1228-x · Cited by 75
Targeting Outpatient Drug Safety
Herwaarden, M. F. W., Kramers, C., Sturkenboom, M., van den Bemt, P. M. L. A., & Smet, P. A. G. M. D. (2012) · Drug Safety · doi:10.2165/11596000-000000000-00000 · Cited by 75
Epstein, M. (2016) · Kidney International Supplements · doi:10.1016/j.kisu.2016.01.004 · Cited by 76
Fleet, J. L., Shariff, S. Z., Gandhi, S., Weir, M. A., Jain, A. K., & Garg, A. X. (2012) · BMJ Open · doi:10.1136/bmjopen-2012-002011 · Cited by 71
Analysis of Factors Causing Hyperkalemia
Takaichi, K., Takemoto, F., Ubara, Y., & Mori, Y. (2007) · Internal Medicine · doi:10.2169/internalmedicine.46.6415 · Cited by 69
Hyperkalemia with RAAS inhibition: Mechanism, clinical significance, and management
Hundemer, G. L., & Sood, M. M. (2021) · Pharmacological Research · doi:10.1016/j.phrs.2021.105835 · Cited by 67
Effects of Presentation and Electrocardiogram on Time to Treatment of Hyperkalemia
Freeman, K., Feldman, J. A., Mitchell, P. M., Donovan, J., Dyer, K. S., Eliseo, L. J., White, L. F., & Temin, E. S. (2008) · Academic Emergency Medicine · doi:10.1111/j.1553-2712.2008.00058.x · Cited by 67
Barrera‐Chimal, J., Prince, S., Fadel, F., Moghrabi, S. E., Warnock, D. G., Kolkhof, P., & Jaisser, F. (2015) · Journal of the American Society of Nephrology · doi:10.1681/asn.2014121216 · Cited by 65
Beccari, M. V., & Meaney, C. J. (2017) · Core evidence · doi:10.2147/ce.s129555 · Cited by 65
Serum Potassium in the PARADIGM-HF Trial
Ferreira, J. P., Mogensen, U. M., Jhund, P. S., Desai, A. S., Rouleau, J. L., Zile, M. R., Rossignol, P., Zannad, F. M., Packer, M., Solomon, S. D., et al. (2020) · European Journal of Heart Failure · doi:10.1002/ejhf.1987 · Cited by 64
Roblek, T., Detiček, A., Leskovar, B., Šuškovič, S., Horvat, M., Belic, A., Mrhar, A., & Lainščak, M. (2015) · International Journal of Cardiology · doi:10.1016/j.ijcard.2015.10.206 · Cited by 63
Yavin, Y., Mansfield, T. A., Ptaszynska, A., Johnsson, K. M., Parikh, S. J., & JOHNSSON, E. K. (2016) · Diabetes Therapy · doi:10.1007/s13300-015-0150-y · Cited by 62
Blood pressure drug therapy and electrolyte disturbances
Liamis, G. L., Milionis, H. J., & Elisaf, M. (2008) · International Journal of Clinical Practice · doi:10.1111/j.1742-1241.2008.01860.x · Cited by 61
CKD as an Underrecognized Threat to Patient Safety
Fink, J. C., Brown, J., Hsu, V. D., Seliger, S. L., Walker, L. D., & Zhan, M. (2009) · American Journal of Kidney Diseases · doi:10.1053/j.ajkd.2008.12.016 · Cited by 60
Hyperkalemia in patients with heart failure: Incidence, prevalence, and management
Desai, A. S. (2009) · Current Heart Failure Reports · doi:10.1007/s11897-009-0037-1 · Cited by 59
Abbas, S., Ihle, P., Harder, S., & Schübert, I. (2015) · Pharmacoepidemiology and Drug Safety · doi:10.1002/pds.3748 · Cited by 59
Pitt, B., Bushinsky, D. A., Kitzman, D. W., Ruschitzka, F. T., Metra, M., Filippatos, G. S., Rossignol, P., Mond, C. D., Garza, D., Berman, L., et al. (2018) · ESC Heart Failure · doi:10.1002/ehf2.12265 · Cited by 58
Metadata
- Authors
- Palmer, B. F.
- Affiliations
- The University of Texas Southwestern Medical Center (US)
- Corresponding author
- Palmer, Biff F.
- ORCID
- Palmer, Biff F.
- Venue
- New England Journal of Medicine
- Publisher
- Massachusetts Medical Society
- Published
- 2004-08-05
- Volume
- 351
- Issue
- 6
- Pages
- 585-592
- ISSN
- 0028-4793 (ISSN-L)
- 1533-4406
- OpenAlex
- W2093767567
- Semantic Scholar
- 58d9c67c801fe4f1082d485f5f4497ed175693d9
- Cited by
- 640
- References
- 59
- Citations by year
- 2026: 19 · 2025: 29 · 2024: 28 · 2023: 28 · 2022: 24 · 2021: 23 · 2020: 34 · 2019: 28 · 2018: 35 · 2017: 42 · 2016: 31 · 2015: 28 · 2014: 30 · 2013: 21 · 2012: 37
- FWCI
- 4.89
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- New England Journal of Medicine (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Nephrology › Potassium and Related Disorders
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Renin-Angiotensin System Studies
- Health Sciences › Medicine › Hematology › Coagulation, Bradykinin, Polyphosphates, and Angioedema
- Keywords
- hyperkalemia, renin-angiotensin-aldosterone system inhibitors, ACE inhibitors, angiotensin receptor blockers, drug-induced hyperkalemia, pathophysiology, diabetes mellitus, heart failure, chronic kidney disease, elderly patients, hyperkalemia management
- MeSH terms
- Aldosterone, Angiotensin-Converting Enzyme Inhibitors, Humans, Hyperkalemia, Kidney, Potassium, Renin-Angiotensin System, Risk Factors, Sodium, Angiotensin Receptor Antagonists
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review