Multiplicity Considerations in Clinical Trials

Cardiovascular morbidity and mortality in the losartan intervention for endpoint reduction in hypertension study (LIFE): A randomised trial against atenolol

Dahlöf, B., Devereux, R. B., Kjeldsen, S. E., Julius, S., Beevers, G., de Faire, U., Fyhrquist, F., Ibsen, H., Kristiansson, K., Lederballe-Pedersen, O., et al. (2002) · The Lancet · doi:10.1016/s0140-6736(02)08089-3 · Cited by 5,407

Enzalutamide in Metastatic Prostate Cancer before Chemotherapy

Beer, T. M., Armstrong, A. J., Rathkopf, D. E., Loriot, Y., Sternberg, C. N., Higano, C. S., Iversen, P., Bhattacharya, S., Carles, J., Chowdhury, S., et al. (2014) · New England Journal of Medicine · doi:10.1056/nejmoa1405095 · Cited by 3,028

Abiraterone in Metastatic Prostate Cancer without Previous Chemotherapy

Ryan, C. J., Smith, M. R., de Bono, J. S., Molina, A., Logothetis, C. J., de Souza, P., Fizazi, K., Mainwaring, P., Piulats, J. M., Ng, S., et al. (2013) · New England Journal of Medicine · doi:10.1056/nejmoa1209096 · Cited by 2,796

Increased MET Gene Copy Number Negatively Affects Survival of Surgically Resected Non–Small-Cell Lung Cancer Patients

Cappuzzo, F., Marchetti, A., Skokan, M. C., Rossi, E., Gajapathy, S., Felicioni, L., Grammastro, M. D., Sciarrotta, M., Buttitta, F., Incarbone, M., et al. (2009) · Journal of Clinical Oncology · doi:10.1200/jco.2008.19.1635 · Cited by 563

Extended Thromboprophylaxis with Betrixaban in Acutely Ill Medical Patients

Cohen, A. T., Harrington, R. A., Goldhaber, S. Z., Hull, R. D., Wiens, B. L., Gold, A., Hernandez, A. F., & Gibson, C. M. (2016) · New England Journal of Medicine · doi:10.1056/nejmoa1601747 · Cited by 439

Combining Multiple Comparisons and Modeling Techniques in Dose‐Response Studies

Bretz, F., Pinheiro, J. C., & Branson, M. (2005) · Biometrics · doi:10.1111/j.1541-0420.2005.00344.x · Cited by 399

Tutorial in biostatistics: data‐driven subgroup identification and analysis in clinical trials

Lipkovich, I., Dmitrienko, A., & B., R. (2017) · Statistics in Medicine · doi:10.1002/sim.7064 · Cited by 291

Multiple Testing Problems in Pharmaceutical Statistics

(2009) · Chapman & Hall/CRC eBooks · doi:10.1201/9781584889854 · Cited by 274

Lurasidone in the Treatment of Schizophrenia: A Randomized, Double-Blind, Placebo- and Olanzapine-Controlled Study

Meltzer, H. Y., Cucchiaro, J. B., Silva, R., Ogasa, M., Phillips, D., Xu, J., Kalali, A. H., Schweizer, E. E., Pikalov, A., & Loebel, A. D. (2011) · American Journal of Psychiatry · doi:10.1176/appi.ajp.2011.10060907 · Cited by 251

Multiple testing in clinical trials

Bauer, P. (1991) · Statistics in Medicine · doi:10.1002/sim.4780100609 · Cited by 241

First-line atezolizumab plus chemotherapy in extensive-stage small-cell lung cancer

Horn, L., Mansfield, A. S., Szczęsna, A., Havel, L., Krzakowski, M., Hochmair, M. J., Huemer, F., Losonczy, G., Johnson, M. L., Nishio, M., et al. (2018) · New England Journal of Medicine · doi:10.1056/nejmoa1809064 · Cited by 3,586

Albiglutide and cardiovascular outcomes in patients with type 2 diabetes and cardiovascular disease (Harmony Outcomes): A double-blind, randomised placebo-controlled trial

Hernandez, A. F., Green, J. B., Janmohamed, S., D'Agostino, R. B., Granger, C. B., Jones, N. P., Leiter, L. A., Rosenberg, A. E., Sigmon, K. N., Somerville, M. C., et al. (2018) · The Lancet · doi:10.1016/s0140-6736(18)32261-x · Cited by 1,829

Overall Survival with Palbociclib and Fulvestrant in Advanced Breast Cancer

Turner, N. C., Slamon, D. J., Ro, J., Bondarenko, I., Im, S.-A., Masuda, N., Colleoni, M., DeMichele, A., Loi, S., Verma, S., et al. (2018) · New England Journal of Medicine · doi:10.1056/nejmoa1810527 · Cited by 1,276

Overall survival with ribociclib plus endocrine therapy in breast cancer

Im, S.-A., Lu, Y.-S., Bardia, A., Harbeck, N., Colleoni, M., Franke, F., Chow, L., Sohn, J., Lee, K.-S., Campos-Gomez, S., et al. (2019) · New England Journal of Medicine · doi:10.1056/nejmoa1903765 · Cited by 1,001

Eculizumab in Aquaporin-4–Positive Neuromyelitis Optica Spectrum Disorder

Pittock, S. J., Berthele, A., Fujihara, K., Kim, H. J., Levy, M., Palace, J. A., Nakashima, I., Terzi, M., Totolyan, N. A., Viswanathan, S., et al. (2019) · New England Journal of Medicine · doi:10.1056/nejmoa1900866 · Cited by 887

Trial of Spesolimab for Generalized Pustular Psoriasis

Bachelez, H., Choon, S. E., Marrakchi, S., Burden, A. D., Tsai, T., Morita, A., Navarini, A. A., Zheng, M., Xu, J., Turki, H., et al. (2021) · New England Journal of Medicine · doi:10.1056/nejmoa2111563 · Cited by 372

New Guidelines for Statistical Reporting in the Journal

Harrington, D. P., D’Agostino, R. B., Gatsonis, C., Hogan, J. W., Hunter, D. J., Normand, S. T., Drazen, J. M., & Hamel, M. B. (2019) · New England Journal of Medicine · doi:10.1056/nejme1906559 · Cited by 337

Effect of Initial Management With Aflibercept vs Laser Photocoagulation vs Observation on Vision Loss Among Patients With Diabetic Macular Edema Involving the Center of the Macula and Good Visual Acuity

Baker, C. W., Glassman, A. R., Beaulieu, W. T., Antoszyk, A. N., Browning, D. J., Chalam, K. V., Grover, S., Jampol, L. M., Jhaveri, C. D., Melia, M., et al. (2019) · JAMA · doi:10.1001/jama.2019.5790 · Cited by 299

Drug-Coated Balloons for Dysfunctional Dialysis Arteriovenous Fistulas

Lookstein, R., Haruguchi, H., Ouriel, K. M., Weinberg, I., Lei, L., Cihlar, S., & Holden, A. H. (2020) · New England Journal of Medicine · doi:10.1056/nejmoa1914617 · Cited by 223

Advances in molecular pathology and therapy of non-small cell lung cancer

Huang, Q., Li, Y., Huang, Y., Wu, J., Bao, W., Xue, C., Li, X., Dong, S., Dong, Z., & Hu, S. (2025) · Signal Transduction and Targeted Therapy · doi:10.1038/s41392-025-02243-6 · Cited by 197

SPIRIT 2025 explanation and elaboration: updated guideline for protocols of randomised trials

Hróbjartsson, A., Boutron, I., Hopewell, S., Moher, D., Schulz, K. F., Collins, G. S., Tunn, R., Aggarwal, R., Berkwits, M., Berlin, J. A., et al. (2025) · BMJ · doi:10.1136/bmj-2024-081660 · Cited by 171

The Evolution of Master Protocol Clinical Trial Designs: A Systematic Literature Review

Meyer, E. L., Mesenbrink, P. G., Dunger‐Baldauf, C., Fülle, H., Glimm, E., Li, Y., Posch, M., & König, F. (2020) · Clinical Therapeutics · doi:10.1016/j.clinthera.2020.05.010 · Cited by 141

Efficacy and safety of first-line maintenance therapy with lurbinectedin plus atezolizumab in extensive-stage small-cell lung cancer (IMforte): a randomised, multicentre, open-label, phase 3 trial

Paz-Ares, L. G., Borghaei, H., Liu, S. V., Peters, S., Herbst, R. S., Stencel, K. M., Majem, M., Şendur, M. A. N., Czyżewicz, G., Caro, R. B., et al. (2025) · The Lancet · doi:10.1016/s0140-6736(25)01011-6 · Cited by 108

STROKE-CARD care to prevent cardiovascular events and improve quality of life after acute ischaemic stroke or TIA: A randomised clinical trial

Willeit, P., Toell, T., Boehme, C., Krebs, S., Mayer‐Suess, L., Lang, C., Seekircher, L., Tschiderer, L., Willeit, K., Rumpold, G., et al. (2020) · EClinicalMedicine · doi:10.1016/j.eclinm.2020.100476 · Cited by 87

Mapping ongoing nutrition intervention trials in muscle, sarcopenia, and cachexia: a scoping review of future research

Orsso, C. E., Montes‐Ibarra, M., Findlay, M., van der Meij, B. S., de van der Schueren, M. A. E., Landi, F., Laviano, A., & Prado, C. M. (2022) · Journal of Cachexia, Sarcopenia and Muscle · doi:10.1002/jcsm.12954 · Cited by 73

Effectiveness of different combinations of DMARDs and glucocorticoid bridging in early rheumatoid arthritis: two-year results of CareRA

Stouten, V., Westhovens, R., Pazmiño, S., Cock, D. D., der Elst, K. V., Joly, J., Verschueren, P., on behalf of the CareRA study group, Maeyaert, B., Brabanter, G. D., et al. (2019) · Lara D. Veeken · doi:10.1093/rheumatology/kez213 · Cited by 62

Effects of different doses of exercise and diet-induced weight loss on beta-cell function in type 2 diabetes (DOSE-EX): a randomized clinical trial

Legaard, G. E., Lyngbæk, M. P. P., Almdal, T., Karstoft, K., Bennetsen, S. L., Feineis, C. S., Nielsen, N. S., Durrer, C. G., Liebetrau, B., Nystrup, U., et al. (2023) · Nature Metabolism · doi:10.1038/s42255-023-00799-7 · Cited by 55

Common Sense Oncology principles for the design, analysis, and reporting of phase 3 randomised clinical trials

Gyawali, B., Eisenhauer, E. A., van der Graaf, W., Booth, C. M., Cherny, N. I., Goodman, A. M., Koven, R., Pe, M. L., Marini, B. L., Mohyuddin, G. R., et al. (2025) · The Lancet Oncology · doi:10.1016/s1470-2045(24)00451-0 · Cited by 50

Essential statistical principles of clinical trials of pain treatments

Dworkin, R. H., Evans, S. R., Mbowe, O. B., & McDermott, M. (2020) · PAIN Reports · doi:10.1097/pr9.0000000000000863 · Cited by 52

Azithromycin to Reduce Mortality — An Adaptive Cluster-Randomized Trial

O’Brien, K. S., Arzika, A. M., Amza, A., Maliki, R., Aichatou, B., Bello, I. M., Beidi, D., Galo, N., Harouna, A. N., Karamba, A. M., et al. (2024) · New England Journal of Medicine · doi:10.1056/nejmoa2312093 · Cited by 46

Strategies in adjusting for multiple comparisons: A primer for pediatric surgeons

Staffa, S. J., & Zurakowski, D. (2020) · Journal of Pediatric Surgery · doi:10.1016/j.jpedsurg.2020.01.003 · Cited by 44

Individual Patient Data from the Pivotal Randomized Controlled Trials of Non-Vitamin K Antagonist Oral Anticoagulants in Patients with Atrial Fibrillation (COMBINE AF): Design and Rationale

Carnicelli, A., Hong, H., Giugliano, R. P., Connolly, S. J., Eikelboom, J. W., Patel, M. R., Wallentin, L. C., Morrow, D. A., WOJDYLA, D. M., Hua, K., et al. (2020) · American Heart Journal · doi:10.1016/j.ahj.2020.12.002 · Cited by 37

Selective outcome reporting in randomized clinical trials of dental implants

Sendyk, D. I., Rovai, E. S., Souza, N. V., Deboni, M. C. Z., & Pannuti, C. M. (2019) · Journal of Clinical Periodontology · doi:10.1111/jcpe.13128 · Cited by 35

One-year intensive lifestyle intervention and improvements in health-related quality of life and mental health in persons with type 2 diabetes: a secondary analysis of the U-TURN randomized controlled trial

MacDonald, C., Nielsen, S. M., Bjørner, J. B., Johansen, M. Y., Christensen, R., Vaag, A. A., Lieberman, D. E., Pedersen, B. K., Langberg, H., Ried‐Larsen, M., et al. (2021) · BMJ Open Diabetes Research & Care · doi:10.1136/bmjdrc-2020-001840 · Cited by 36

The effect of frequency of activity interruptions in prolonged sitting on postprandial glucose metabolism: A randomized crossover trial

Thorsen, I. K., Johansen, M. Y., Pilmark, N. S., Jespersen, N. Z., Brinkløv, C. F., Benatti, F. B., Dunstan, D. W., Karstoft, K., Pedersen, B. K., & Ried‐Larsen, M. (2019) · Metabolism · doi:10.1016/j.metabol.2019.04.003 · Cited by 35

Sustained Intensive Treatment and Long-term Effects on HbA1c Reduction (SILVER Study) by CGM in People With Type 1 Diabetes Treated With MDI

Lind, M., Ólafsdóttir, A. F., Hirsch, I. B., Bolinder, J., Dahlqvist, S., Pivodic, A., Hellman, J., Wijkman, M. O., Schwarcz, E., Albrektsson, H., et al. (2020) · Diabetes Care · doi:10.2337/dc20-1468 · Cited by 35

Heart Failure End Points in Cardiovascular Outcome Trials of Sodium Glucose Cotransporter 2 Inhibitors in Patients With Type 2 Diabetes Mellitus

Butler, J., Packer, M., Greene, S. J., Fiuzat, M., Anker, S. D., Anstrom, K. J., Carson, P. E., Cooper, L. B., Fonarow, G. C., Hernandez, A. F., et al. (2019) · Circulation · doi:10.1161/circulationaha.119.042155 · Cited by 29

Digital Health Technology to Measure Drug Efficacy in Clinical Trials for Parkinson’s Disease: A Regulatory Perspective

Sacks, L. V., & Kunkoski, E. (2021) · Journal of Parkinson s Disease · doi:10.3233/jpd-202416 · Cited by 27

Efficacy of Risankizumab versus Secukinumab in Patients with Moderate-to-Severe Psoriasis: Subgroup Analysis from the IMMerge Study

Crowley, J., Langley, R. G. B., Gordon, K. B., Pinter, A., Ferris, L. K., Rubant, S., Photowala, H., Xue, Z., Wu, T., Zhan, T., et al. (2022) · Dermatology and Therapy · doi:10.1007/s13555-021-00679-6 · Cited by 27

Dose-Response Effects of Exercise on Glucose-Lowering Medications for Type 2 Diabetes: A Secondary Analysis of a Randomized Clinical Trial

MacDonald, C., Johansen, M. Y., Nielsen, S. M., Christensen, R., Hansen, K. B., Langberg, H., Vaag, A. A., Karstoft, K., Lieberman, D. E., Pedersen, B. K., et al. (2020) · Mayo Clinic Proceedings · doi:10.1016/j.mayocp.2019.09.005 · Cited by 26

A pilot multicentre randomised controlled trial of lidocaine infusion in women undergoing breast cancer surgery

Toner, A. J., Bailey, M., Schug, S. A., & Corcoran, T. B. (2021) · Anaesthesia · doi:10.1111/anae.15440 · Cited by 25

Age-based targeting of biannual azithromycin distribution for child survival in Niger: an adaptive cluster-randomized trial protocol (AVENIR)

the AVENIR Study Group, O’Brien, K. S., Arzika, A. M., Amza, A., Maliki, R., Ousmane, S., Kadri, B., Nassirou, B., Mankara, A. K., Harouna, A. N., et al. (2021) · BMC Public Health · doi:10.1186/s12889-021-10824-7 · Cited by 25

Dosage reduction and discontinuation of biological disease-modifying antirheumatic drugs in patients with rheumatoid arthritis, psoriatic arthritis and axial spondyloarthritis: protocol for a pragmatic, randomised controlled trial (the BIOlogical Dose OPTimisation (BIODOPT) trial)

Uhrenholt, L., Schlemmer, A., Hauge, E., Christensen, R., Dreyer, L., Suarez-Almazor, M. E., & Kristensen, S. (2019) · BMJ Open · doi:10.1136/bmjopen-2018-028517 · Cited by 25

Multiplicity corrections in life sciences: challenges and consequences

Menyhárt, O., & Győrffy, B. (2025) · International Journal of Epidemiology · doi:10.1093/ije/dyaf098 · Cited by 29

Selective outcome reporting in root coverage randomized clinical trials

Sendyk, D. I., Vilela, N., Neto, J. B. C., Tatakis, D. N., & Pannuti, C. M. (2021) · Journal Of Clinical Periodontology · doi:10.1111/jcpe.13451 · Cited by 23

Mesh implants for hernia repair: an update

Klinge, U., & Klosterhalfen, B. (2018) · Expert Review of Medical Devices · doi:10.1080/17434440.2018.1529565 · Cited by 24

Using Bayesian statistics in confirmatory clinical trials in the regulatory setting: a tutorial review

Lee, S. Y. (2024) · BMC Medical Research Methodology · doi:10.1186/s12874-024-02235-0 · Cited by 27

How Not to Fool Ourselves About Heterogeneity of Treatment Effects

von Hippel, P. T., & Schuetze, B. A. (2025) · Advances in Methods and Practices in Psychological Science · doi:10.1177/25152459241304347 · Cited by 29

Prevalence of Multiplicity and Appropriate Adjustments Among Cardiovascular Randomized Clinical Trials Published in Major Medical Journals

Khan, M. S., Khan, M. S., Ansari, Z. N., Siddiqi, T. J., Khan, S. U., Riaz, I. B., Asad, Z. U. A., Mandrola, J. M., Wason, J. M. S., Warraich, H. J., et al. (2020) · JAMA Network Open · doi:10.1001/jamanetworkopen.2020.3082 · Cited by 22

Characteristics of Design and Analysis of Ophthalmic Randomized Controlled Trials

Dong, R., & Ying, G. (2022) · Ophthalmology Science · doi:10.1016/j.xops.2022.100266 · Cited by 22

The handling oxygenation targets in the intensive care unit (HOT‐ICU) trial: Detailed statistical analysis plan

Schjørring, O. L., Klitgaard, T. L., Perner, A., Wetterslev, J., Lange, T., Keus, F., Laake, J. H., Morgan, M., Bäcklund, M., Siegemund, M., et al. (2020) · Acta Anaesthesiologica Scandinavica · doi:10.1111/aas.13569 · Cited by 19

Rethinking clinical endpoints in kidney transplant trials

Maggiore, U., Leventhal, J. S., & Cravedi, P. (2019) · Current Opinion in Organ Transplantation · doi:10.1097/mot.0000000000000719 · Cited by 18

Tracheomalacia and tracheomegaly in infants and children with congenital diaphragmatic hernia managed with and without fetoscopic endoluminal tracheal occlusion (FETO): a multicentre, retrospective cohort study

Basurto, D., Watananirun, K., Cordier, A., Otaño, J., Carrière, D., Scuglia, M., Vargas, A. M. D. L. F., Prat, J., Russo, F. M., Debeer, A., et al. (2024) · The Lancet Child & Adolescent Health · doi:10.1016/s2352-4642(24)00109-3 · Cited by 16

Project Rebuild the Evidence Base (REB): a method to interpret randomised clinical trials and their meta-analysis to present solid benefit-risk assessments to patients.

Boussageon, R., Blanchard, C., Charuel, É., Ménini, T., Pereira, B., Naudet, F., Kassaï, B., Gueyffier, F., Cucherat, M., & Vaillant-Roussel, H. (2022) · Therapies · doi:10.1016/j.therap.2022.10.008 · Cited by 15

The effects of different doses of exercise on pancreatic β-cell function in patients with newly diagnosed type 2 diabetes: study protocol for and rationale behind the “DOSE-EX” multi-arm parallel-group randomised clinical trial

Lyngbæk, M. P. P., Legaard, G. E., Bennetsen, S. L., Feineis, C. S., Rasmussen, V., Moegelberg, N., Brinkløv, C. F., Nielsen, A. B., Kofoed, K. S., Lauridsen, C. A., et al. (2021) · Trials · doi:10.1186/s13063-021-05207-7 · Cited by 15

Examining self-defining memories and aggression in a sample of criminal offenders

Taple, B. J., Zabala-Baños, M. D. C., Jiménez, M. V. J., Griffith, J. W., & Ricarte, J. J. (2018) · Memory · doi:10.1080/09658211.2018.1557209 · Cited by 13

Leveraging Serial Low-Dose CT Scans in Radiomics-based Reinforcement Learning to Improve Early Diagnosis of Lung Cancer at Baseline Screening

Wang, Y., Zhou, C., Ying, L., Lee, E., Chan, H., Chughtai, A. R., Hadjiiski, L. M., & Kazerooni, E. A. (2024) · Radiology Cardiothoracic Imaging · doi:10.1148/ryct.230196 · Cited by 12

Statistical significance and p-values

Parsons, N., Carey-Smith, R. L., Dritsaki, M., Griffin, X. L., Metcalfe, D., Perry, D. C., Stengel, D., & Costa, M. L. (2019) · The Bone & Joint Journal · doi:10.1302/0301-620x.101b10.bjj-2019-0890 · Cited by 11

Causal Considerations Can Inform the Interpretation of Surprising Associations in Medical Registries

Carmona‐Bayonas, A., Jiménez‐Fonseca, P., Gallego-Plazas, J., & Msaouel, P. (2021) · Cancer Investigation · doi:10.1080/07357907.2021.1999971 · Cited by 11

Survival, treatment pattern, and treatment outcome in patients with cervical cancer metastatic to distant lymph nodes

Lin, H., Wang, D., Li, H., Wu, C., Zhang, F., Lin, Z., & Yao, T. (2022) · Frontiers in Oncology · doi:10.3389/fonc.2022.952480 · Cited by 11

Vascular and metabolic effects of ipragliflozin versus sitagliptin (IVS) in type 2 diabetes treated with sulphonylurea and metformin: IVS study

Kang, S. M., Yun, H. M., Sohn, M., & Lim, S. K. (2023) · Diabetes Obesity and Metabolism · doi:10.1111/dom.15056 · Cited by 11

New Anticancer Drugs: Reliably Assessing “Value” While Addressing High Prices

Stewart, D. J., Bradford, J., Sehdev, S. R., Ramsay, T., Navani, V., Rawson, N. S. B., Jiang, D., Gotfrit, J., Wheatley‐Price, P., Liu, G., et al. (2024) · Current Oncology · doi:10.3390/curroncol31050184 · Cited by 10

Optimizing a Bayesian hierarchical adaptive platform trial design for stroke patients

Gao, G., Gajewski, B. J., Wick, J., Beall, J., Saver, J. L., Meinzer, C., Derdeyn, C. P., Fiorella, D. J., Jovin, T. G., Khatri, P., et al. (2022) · Trials · doi:10.1186/s13063-022-06664-4 · Cited by 10

Optimal and Maximin Procedures for Multiple Testing Problems

Rosset, S., Heller, R., Painsky, A., & Aharoni, E. (2022) · Journal of the Royal Statistical Society Series B (Statistical Methodology) · doi:10.1111/rssb.12507 · Cited by 10

Melding microbiome and nutritional science with early child development

Chen, R. Y., Mostafa, I., Hibberd, M. C., Das, S., Lynn, H. M., Webber, D. M., Mahfuz, M., Barratt, M. J., Ahmed, T., & Gordon, J. I. (2021) · Nature Medicine · doi:10.1038/s41591-021-01451-1 · Cited by 10

Data-Driven and Confirmatory Subgroup Analysis in Clinical Trials

Dmitrienko, A. A., Lipkovich, I. A., Dane, A. L., & Muysers, C. (2020) · Emerging topics in statistics and biostatistics · doi:10.1007/978-3-030-40105-4_3 · Cited by 11

Outcomes by sex in the International Study of Comparative Health Effectiveness With Medical and Invasive Approaches (ISCHEMIA) trial

Gaudino, M. F. L., Alexander, J. H., Sandner, S. E., Harik, L., Kim, J., Stone, G. W., Rahouma, M., O’Gara, P. T., Bhatt, D. L., & Redfors, B. (2024) · EuroIntervention · doi:10.4244/eij-d-24-00011 · Cited by 9

The influence of familiarity between the surgeon and their assistant on patient outcomes: a prospective observational cohort study

Stelzl, D. R., Polazzi, S., Lifante, J., Dey, T., & Duclos, A. (2025) · International Journal of Surgery · doi:10.1097/js9.0000000000002269 · Cited by 8

Towards precision medicine in clinical trials for the treatment of urologic chronic pelvic pain syndrome: lessons from the MAPP Research Network

Stephens‐Shields, A. J., Clemens, J. Q., Pontari, M. A., Lai, H. H., Moldwin, R., Williams, D. A., Bradley, C. S., Farrar, J. T., Landis, J. R., Mullins, C. E., et al. (2025) · Nature Reviews Urology · doi:10.1038/s41585-025-01030-w · Cited by 8

Association of circulating 25-hydroxyvitamin D and parathyroid hormone with carotid intima media thickness in children and adolescents with excess weight

Asghari, G., Mirmiran, P., Yuzbashian, E., Dehghan, P., Mahdavi, M., Tohidi, M., Wagner, C. L., Neyestani, T. R., Hosseinpanah, F., & Azizi, F. (2018) · The Journal of Steroid Biochemistry and Molecular Biology · doi:10.1016/j.jsbmb.2018.12.015 · Cited by 8

Finding the hot spot: identifying immune sensitive gastrointestinal tumors

de Souza, A. L. P. B. (2020) · Translational Gastroenterology and Hepatology · doi:10.21037/tgh.2019.12.11 · Cited by 7

Design and reporting of phase III oncology trials with prospective biomarker validation

Liang, F., Peng, L., Wu, Z., Giamas, G., & Stebbing, J. (2022) · JNCI Journal of the National Cancer Institute · doi:10.1093/jnci/djac210 · Cited by 8

The Protective Role of Physical Fitness on Cardiometabolic Risk During Pregnancy: The GESTAtion and FITness Project

Acosta‐Manzano, P., Acosta, F. M., Flor‐Alemany, M., Gavilán‐Carrera, B., Delgado‐Fernández, M., Baena‐García, L., Segura‐Jiménez, V., & Aparicio, V. A. (2022) · International Journal of Sport Nutrition and Exercise Metabolism · doi:10.1123/ijsnem.2021-0274 · Cited by 6

Interpretation of clinical studies in electrophysiology: statistical considerations for the clinician

Chieng, D., Finch, S. J., Sugumar, H., Taylor, A. J., Reid, C. M., Kalman, J. M., & Kistler, P. M. (2020) · EP Europace · doi:10.1093/europace/euaa308 · Cited by 6

Effects of vitamin K2 supplementation on atherogenic status of individuals with type 2 diabetes: a randomized controlled trial

Sakak, F. R., Moslehi, N., Abdi, H., & Mirmiran, P. (2021) · BMC Complementary Medicine and Therapies · doi:10.1186/s12906-021-03304-3 · Cited by 6

Risk Model Development and Validation in Clinical Oncology: Lessons Learned

Lyman, G. H., Msaouel, P., & Kuderer, N. M. (2022) · Cancer Investigation · doi:10.1080/07357907.2022.2137914 · Cited by 6

Timing and Reporting of Secondary Overall Survival End Points for Phase III Trials in Advanced/Metastatic Disease

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