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A National Evaluation of the Effect of Trauma-Center Care on Mortality
Open accessAbstract
BACKGROUND: Hospitals have difficulty justifying the expense of maintaining trauma centers without strong evidence of their effectiveness. To address this gap, we examined differences in mortality between level 1 trauma centers and hospitals without a trauma center (non-trauma centers). METHODS: Mortality outcomes were compared among patients treated in 18 hospitals with a level 1 trauma center and 51 hospitals non-trauma centers located in 14 states. Patients 18 to 84 years old with a moderate-to-severe injury were eligible. Complete data were obtained for 1104 patients who died in the hospital and 4087 patients who were discharged alive. We used propensity-score weighting to adjust for observable differences between patients treated at trauma centers and those treated at non-trauma centers. RESULTS: After adjustment for differences in the case mix, the in-hospital mortality rate was significantly lower at trauma centers than at non-trauma centers (7.6 percent vs. 9.5 percent; relative risk, 0.80; 95 percent confidence interval, 0.66 to 0.98), as was the one-year mortality rate (10.4 percent vs. 13.8 percent; relative risk, 0.75; 95 percent confidence interval, 0.60 to 0.95). The effects of treatment at a trauma center varied according to the severity of injury, with evidence to suggest that differences in mortality rates were primarily confined to patients with more severe injuries. CONCLUSIONS: Our findings show that the risk of death is significantly lower when care is provided in a trauma center than in a non-trauma center and argue for continued efforts at regionalization.
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Cites
Multiple Imputation for Nonresponse in Surveys
Rubin, D. B. (1987) · Wiley Series in Probability and Statistics · doi:10.1002/9780470316696 · Cited by 20,701
Marginal Structural Models and Causal Inference in Epidemiology
Robins, J. M., Hernán, M. Á., & Brumback, B. (2000) · Epidemiology · doi:10.1097/00001648-200009000-00011 · Cited by 5,581
Cited by
Deakin, C. D., Nolan, J. P., Soar, J., Sunde, K., Koster, R. W., Smith, G. B., & Perkins, G. D. (2010) · Resuscitation · doi:10.1016/j.resuscitation.2010.08.017 · Cited by 2,700
Moderate and severe traumatic brain injury in adults
Maas, A. I., Stocchetti, N., & Bullock, R. (2008) · The Lancet Neurology · doi:10.1016/s1474-4422(08)70164-9 · Cited by 2,123
European Resuscitation Council Guidelines for Resuscitation 2010 Section 1. Executive summary
Nolan, J. P., Soar, J., Zideman, D. A., Biarent, D., Bossaert, L. L., Deakin, C., Koster, R. W., Wyllie, J., & Böttiger, B. (2010) · Resuscitation · doi:10.1016/j.resuscitation.2010.08.021 · Cited by 1,375
Nolan, J. P., Soar, J., Cariou, A., Cronberg, T., Moulaert, V. R. M., Deakin, C. D., Bottiger, B. W., Friberg, H., Sunde, K., & Sandroni, C. (2015) · Resuscitation · doi:10.1016/j.resuscitation.2015.07.018 · Cited by 1,116
Gonzalez, E., Moore, E. E., Moore, H. B., Chapman, M. P., Chin, T. L., Ghasabyan, A., Wohlauer, M. V., Barnett, C. C., Bensard, D. D., Biffl, W. L., et al. (2016) · Annals of Surgery · doi:10.1097/sla.0000000000001608 · Cited by 641
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Metadata
- Authors
- MacKenzie, E. J., Rivara, F. P., Jurkovich, G. J., Nathens, A. B., Frey, K. P., Egleston, B. L., Salkever, D. S., & Scharfstein, D. O.
- Venue
- New England Journal of Medicine
- Publisher
- Massachusetts Medical Society
- Published
- 2006-01-26
- Volume
- 354
- Issue
- 4
- Pages
- 366-378
- ISSN
- 0028-4793 (ISSN-L)
- 1533-4406
- OpenAlex
- W2083066201
- Cited by
- 2,578
- References
- 2
- FWCI
- 101.34
- Type
- journal article
- Language
- en
- Open access
- bronze
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- MacKenzie, E. J., Rivara, F. P., Jurkovich, G. J., Nathens, A. B., Frey, K. P., Egleston, B. L., Salkever, D. S., & Scharfstein, D. O. (2006). A National Evaluation of the Effect of Trauma-Center Care on Mortality. New England Journal of Medicine. https://doi.org/10.1056/nejmsa052049
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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