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A National Evaluation of the Effect of Trauma-Center Care on Mortality

Open access
MacKenzie, Ellen J., Rivara, Frederick P., Jurkovich, Gregory J., Nathens, Avery B., Frey, Katherine P., Egleston, Brian L., Salkever, David S., Scharfstein, Daniel O.·2006·New England Journal of Medicine

Abstract

BACKGROUND: Hospitals have difficulty justifying the expense of maintaining trauma centers without strong evidence of their effectiveness. To address this gap, we examined differences in mortality between level 1 trauma centers and hospitals without a trauma center (non-trauma centers). METHODS: Mortality outcomes were compared among patients treated in 18 hospitals with a level 1 trauma center and 51 hospitals non-trauma centers located in 14 states. Patients 18 to 84 years old with a moderate-to-severe injury were eligible. Complete data were obtained for 1104 patients who died in the hospital and 4087 patients who were discharged alive. We used propensity-score weighting to adjust for observable differences between patients treated at trauma centers and those treated at non-trauma centers. RESULTS: After adjustment for differences in the case mix, the in-hospital mortality rate was significantly lower at trauma centers than at non-trauma centers (7.6 percent vs. 9.5 percent; relative risk, 0.80; 95 percent confidence interval, 0.66 to 0.98), as was the one-year mortality rate (10.4 percent vs. 13.8 percent; relative risk, 0.75; 95 percent confidence interval, 0.60 to 0.95). The effects of treatment at a trauma center varied according to the severity of injury, with evidence to suggest that differences in mortality rates were primarily confined to patients with more severe injuries. CONCLUSIONS: Our findings show that the risk of death is significantly lower when care is provided in a trauma center than in a non-trauma center and argue for continued efforts at regionalization.

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Metadata

Authors
MacKenzie, E. J., Rivara, F. P., Jurkovich, G. J., Nathens, A. B., Frey, K. P., Egleston, B. L., Salkever, D. S., & Scharfstein, D. O.
Venue
New England Journal of Medicine
Published
2006-01-26
Volume
354
Issue
4
Pages
366-378
ISSN
  • 0028-4793 (ISSN-L)
  • 1533-4406
OpenAlex
W2083066201
Cited by
2,578
References
2
FWCI
101.34
Type
journal article
Language
en
Open access
bronze

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CoChat. (2026). Citation check: A National Evaluation of the Effect of Trauma-Center Care on Mortality. https://app.cochat.ai/papers/10.1056/nejmsa052049
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MacKenzie, E. J., Rivara, F. P., Jurkovich, G. J., Nathens, A. B., Frey, K. P., Egleston, B. L., Salkever, D. S., & Scharfstein, D. O. (2006). A National Evaluation of the Effect of Trauma-Center Care on Mortality. New England Journal of Medicine. https://doi.org/10.1056/nejmsa052049

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