The DOI matches its Crossref record; 3 of the 3 references it cites were found in a registry or an index.
Equipoise and the Dilemma of Randomized Clinical Trials
Abstract
Clinical equipoise, or uncertainty about which treatment is best for a patient, is widely viewed as essential for an ethical RCT. The authors argue that clinical trials that violate equipoise are ethical and necessary to inform societal decisions about drug approval and coverage.
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Citations
Cites
Writing Group for the Women's Health Initiative Investigators (2002) · JAMA: The Journal of the American Medical Association · doi:10.1001/jama.288.3.321 · Cited by 15,889
Estrogen plus Progestin and the Risk of Coronary Heart Disease
Manson, J. E., Hsia, J., Johnson, K. C., Rossouw, J. E., Assaf, A. R., Lasser, N. L., Trevisan, M., Black, H. R., Heckbert, S. R., Detrano, R., et al. (2003) · New England Journal of Medicine · doi:10.1056/nejmoa030808 · Cited by 2,065
Bench to Bedside: Mapping the Moral Terrain of Clinical Research
Joffe, S., & Miller, F. G. (2008) · Hastings Center Report · doi:10.1353/hcr.2008.0019 · Cited by 122
Self-citation
Cited by
Donovan, J. L., Paramasivan, S., de Salis, I., & Toerien, M. (2014) · Trials · doi:10.1186/1745-6215-15-5 · Cited by 262
Rooshenas, L., Elliott, D., Wade, J., Jepson, M., Paramasivan, S., Strong, S., Wilson, C., Beard, D., Blazeby, J. M., Birtle, A., et al. (2016) · PLOS Medicine · doi:10.1371/journal.pmed.1002147 · Cited by 140
Compassionate Use: A Story of Ethics and Science in the Development of a New Drug
Buhles, W. C. (2011) · Perspectives in Biology and Medicine · doi:10.1353/pbm.2011.0027 · Cited by 24
Vercellini, P., Somigliana, E., Cortinovis, I., Bracco, B., de Braud, L., Dridi, D., & Milani, S. (2015) · BMC Women's Health · doi:10.1186/s12905-015-0248-4 · Cited by 22
Metadata
- Authors
- Miller, F. G., & Joffe, S.
- Venue
- New England Journal of Medicine
- Publisher
- Massachusetts Medical Society
- Published
- 2011-02-03
- Volume
- 364
- Issue
- 5
- Pages
- 476-480
- ISSN
- 0028-4793 (ISSN-L)
- 1533-4406
- OpenAlex
- W2072632162
- Cited by
- 189
- References
- 3
- FWCI
- 23.23
- Type
- journal article
- Language
- en
- Open access
- closed
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- Miller, F. G., & Joffe, S. (2011). Equipoise and the Dilemma of Randomized Clinical Trials. New England Journal of Medicine. https://doi.org/10.1056/nejmsb1011301
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
