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Cited by 703

The DOI matches its Crossref record; 6 of the 6 references it cites were found in a registry or an index.

Modular organization of cellular networks

Open access
Rives, Alexander W., Galitski, Timothy·2003·Proceedings of the National Academy of Sciences

Abstract

We investigated the organization of interacting proteins and protein complexes into networks of modules. A network-clustering method was developed to identify modules. This method of network-structure determination was validated by clustering known signaling-protein modules and by identifying module rudiments in exclusively high-throughput protein-interaction data with high error frequencies and low coverage. The signaling network controlling the yeast developmental transition to a filamentous form was clustered. Abstraction of a modular network-structure model identified module-organizer proteins and module-connector proteins. The functions of these proteins suggest that they are important for module function and intermodule communication.

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Metadata

Authors
Rives, A. W., & Galitski, T.
Venue
Proceedings of the National Academy of Sciences
Published
2003-01-21
Volume
100
Issue
3
Pages
1128-1133
ISSN
  • 0027-8424 (ISSN-L)
  • 1091-6490
OpenAlex
W2081931663
Cited by
703
References
6
FWCI
16.62
Type
journal article
Language
en
Open access
bronze

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CoChat. (2026). Citation check: Modular organization of cellular networks. https://app.cochat.ai/papers/10.1073/pnas.0237338100
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Rives, A. W., & Galitski, T. (2003). Modular organization of cellular networks. Proceedings of the National Academy of Sciences. https://doi.org/10.1073/pnas.0237338100

Data sources

Bibliographic data: Semantic Scholar, OpenAlex, Crossref.

Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.