The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.
A prominent role for the CBF cold response pathway in configuring the low-temperature metabolome of Arabidopsis
Open accessAbstract
The Arabidopsis CBF cold response pathway has a central role in cold acclimation, the process whereby plants increase in freezing tolerance in response to low nonfreezing temperatures. Here we examined the changes that occur in the Arabidopsis metabolome in response to low temperature and assessed the role of the CBF cold response pathway in bringing about these modifications. Of 434 metabolites monitored by GC-time-of-flight MS, 325 (75%) were found to increase in Arabidopsis Wassilewskija-2 (Ws-2) plants in response to low temperature. Of these 325 metabolites, 256 (79%) also increased in nonacclimated Ws-2 plants in response to overexpression of C-repeat/dehydration responsive element-binding factor (CBF)3. Extensive cold-induced changes also occurred in the metabolome of Arabidopsis Cape Verde Islands-1 (Cvi-1) plants, which were found to be less freezing tolerant than Ws-2 plants. However, low-temperature-induced expression of CBF1, CBF2, CBF3 , and CBF-targeted genes was much lower in Cvi-1 than in Ws-2 plants, and the low-temperature metabolome of Cvi-1 plants was depleted in metabolites affected by CBF3 overexpression. Taken together, the results indicate that the metabolome of Arabidopsis is extensively reconfigured in response to low temperature, and that the CBF cold response pathway has a prominent role in this process.
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Stockinger, E. J., Gilmour, S. J., & Thomashow, M. F. (1997) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.94.3.1035 · Cited by 1,807
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Arisz, S. A., van Wijk, R., Roels, W., Zhu, J.-K., Haring, M. A., & Munnik, T. (2013) · Frontiers in Plant Science · doi:10.3389/fpls.2013.00001 · Cited by 1,922
Research on plant abiotic stress responses in the post‐genome era: past, present and future
Hirayama, T., & Shinozaki, K. (2010) · The Plant Journal · doi:10.1111/j.1365-313x.2010.04124.x · Cited by 1,215
Licausi, F., Ohme‐Takagi, M., & Perata, P. (2013) · New Phytologist · doi:10.1111/nph.12291 · Cited by 1,020
Li, P., Li, Y., Zhang, F., Zhang, G., Jiang, X., Yu, H., & Hou, B. (2017) · The Plant Journal · doi:10.1111/tpj.13324 · Cited by 574
Salam, U., Ullah, S., Tang, Z.-H., Elateeq, A. A., Khan, Y., Khan, J., Khan, A., & Ali, S. (2023) · Life · doi:10.3390/life13030706 · Cited by 480
Metadata
- Authors
- Cook, D., Fowler, S., Fiehn, O., & Thomashow, M. F.
- Venue
- Proceedings of the National Academy of Sciences
- Published
- 2004-09-21
- Volume
- 101
- Issue
- 42
- Pages
- 15243-15248
- ISSN
- 0027-8424 (ISSN-L)
- 1091-6490
- OpenAlex
- W2150029852
- Cited by
- 700
- References
- 2
- FWCI
- 35.24
- Type
- journal article
- Language
- en
- Open access
- green
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