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The complete genomic sequence of Nocardia farcinica IFM 10152
Open accessAbstract
We determined the genomic sequence of Nocardia farcinica IFM 10152, a clinical isolate, and revealed the molecular basis of its versatility. The genome consists of a single circular chromosome of 6,021,225 bp with an average G+C content of 70.8% and two plasmids of 184,027 (pNF1) and 87,093 (pNF2) bp with average G+C contents of 67.2% and 68.4%, respectively. The chromosome encoded 5,674 putative protein-coding sequences, including many candidate genes for virulence and multidrug resistance as well as secondary metabolism. Analyses of paralogous protein families suggest that gene duplications have resulted in a bacterium that can survive not only in soil environments but also in animal tissues, resulting in disease.
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Cites
Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence
Cole, S. T., Brosch, R., Parkhill, J., Garnier, T., Churcher, C., Harris, D., Gordon, S. V., Eiglmeier, K., Gas, S., Barry, C. E., et al. (1998) · Nature · doi:10.1038/31159 · Cited by 7,847
Cited by
Nocardia thailandica Pulmonary Nocardiosis in a Post-Solid Organ Transplant Patient
Canterino, J., Paniz-Mondolfi, A., Brown-Elliott, B. A., Vientos, W., Vasireddy, R., Wallace, R. J., & Campbell, S. (2015) · Journal of Clinical Microbiology · doi:10.1128/jcm.00959-15 · Cited by 4
Metadata
- Authors
- Ishikawa, J., Yamashita, A., Mikami, Y., Hoshino, Y., Kurita, H., Hotta, K., Shiba, T., & Hattori, M.
- Venue
- Proceedings of the National Academy of Sciences
- Published
- 2004-10-04
- Volume
- 101
- Issue
- 41
- Pages
- 14925-14930
- ISSN
- 0027-8424 (ISSN-L)
- 1091-6490
- OpenAlex
- W1980789643
- Cited by
- 295
- References
- 1
- FWCI
- 30.10
- Type
- journal article
- Language
- en
- Open access
- green
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- Ishikawa, J., Yamashita, A., Mikami, Y., Hoshino, Y., Kurita, H., Hotta, K., Shiba, T., & Hattori, M. (2004). The complete genomic sequence of Nocardia farcinica IFM 10152. Proceedings of the National Academy of Sciences. https://doi.org/10.1073/pnas.0406410101
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