The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
Structure of bacterial tubulin BtubA/B: Evidence for horizontal gene transfer
Open accessAbstract
αβ-Tubulin heterodimers, from which the microtubules of the cytoskeleton are built, have a complex chaperone-dependent folding pathway. They are thought to be unique to eukaryotes, whereas the homologue FtsZ can be found in bacteria. The exceptions are BtubA and BtubB from Prosthecobacter , which have higher sequence homology to eukaryotic tubulin than to FtsZ. Here we show that some of their properties are different from tubulin, such as weak dimerization and chaperone-independent folding. However, their structure is strikingly similar to tubulin including surface loops, and BtubA/B form tubulin-like protofilaments. Presumably, BtubA/B were transferred from a eukaryotic cell by horizontal gene transfer because their high degree of similarity to eukaryotic genes is unique within the Prosthecobacter genome.
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Citations
Cites
Bacterial actins? An evolutionary perspective
Doolittle, R. F., & York, A. L. (2002) · BioEssays · doi:10.1002/bies.10079 · Cited by 33
Cited by
Horizontal gene transfer in eukaryotic evolution
Keeling, P. J., & Palmer, J. D. (2008) · Nature Reviews Genetics · doi:10.1038/nrg2386 · Cited by 1,355
Eukaryotic organisms in Proterozoic oceans
Knoll, A. H., Javaux, E. J., Hewitt, D., & Cohen, P. (2006) · Philosophical Transactions of the Royal Society B: Biological Sciences · doi:10.1098/rstb.2006.1843 · Cited by 701
Wagner, M., & Horn, M. (2006) · Current Opinion in Biotechnology · doi:10.1016/j.copbio.2006.05.005 · Cited by 465
Tubulin binding blocks mitochondrial voltage-dependent anion channel and regulates respiration
Rostovtseva, T. K., Sheldon, K. L., Hassanzadeh, E., Monge, C., Saks, V., Bezrukov, S. M., & Sackett, D. L. (2008) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0806303105 · Cited by 366
Shih, Y.-L., & Rothfield, L. (2006) · Microbiology and Molecular Biology Reviews · doi:10.1128/mmbr.00017-06 · Cited by 266
Metadata
- Authors
- Schlieper, D., Oliva, M. A., Andreu, J. M., & Löwe, J.
- Venue
- Proceedings of the National Academy of Sciences
- Published
- 2005-06-20
- Volume
- 102
- Issue
- 26
- Pages
- 9170-9175
- ISSN
- 0027-8424 (ISSN-L)
- 1091-6490
- OpenAlex
- W2082487283
- Cited by
- 167
- References
- 1
- FWCI
- 5.81
- Type
- journal article
- Language
- en
- Open access
- green
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- Schlieper, D., Oliva, M. A., Andreu, J. M., & Löwe, J. (2005). Structure of bacterial tubulin BtubA/B: Evidence for horizontal gene transfer. Proceedings of the National Academy of Sciences. https://doi.org/10.1073/pnas.0502859102
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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