The DOI matches its Crossref record; 31 of the 31 references it cites were found in a registry or an index.
Filamin A (FLNA) is required for cell–cell contact in vascular development and cardiac morphogenesis
Open accessAbstract
Mutations in the human Filamin A ( FLNA ) gene disrupt neuronal migration to the cerebral cortex and cause cardiovascular defects. Complete loss of Flna in mice results in embryonic lethality with severe cardiac structural defects involving ventricles, atria, and outflow tracts, as well as widespread aberrant vascular patterning. Despite these widespread developmental defects, migration and motility of many cell types does not appear to be affected. Instead, Flna-null embryos display abnormal epithelial and endothelial organization and aberrant adherens junctions in developing blood vessels, heart, brain, and other tissues. Essential roles for FLNA in intercellular junctions provide a mechanism for the diverse developmental defects seen in patients with FLNA mutations.
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Self-citationFilamins as integrators of cell mechanics and signalling
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Self-citationThe many faces of filamin: A versatile molecular scaffold for cell motility and signalling
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Cited by
Lessons on the pathogenesis of aneurysm from heritable conditions
Lindsay, M. E., & Dietz, H. C. (2011) · Nature · doi:10.1038/nature10145 · Cited by 473
The filamins: Organizers of cell structure and function
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Self-citationGuiding Neuronal Cell Migrations
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Mitral valve disease—morphology and mechanisms
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Piezo1 in Smooth Muscle Cells Is Involved in Hypertension-Dependent Arterial Remodeling
Retailleau, K., Duprat, F., Arhatte, M., Ranade, S. S., Peyronnet, R., Martins, J. R., Jodar, M., Moro, C., Offermanns, S., Feng, Y., et al. (2015) · Cell Reports · doi:10.1016/j.celrep.2015.09.072 · Cited by 355
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Metadata
- Authors
- Feng, Y., Chen, M. H., Moskowitz, I. P., Mendonza, A. M., Vidali, L., Nakamura, F., Kwiatkowski, D. J., & Walsh, C. A.
- Venue
- Proceedings of the National Academy of Sciences
- Published
- 2006-12-26
- Volume
- 103
- Issue
- 52
- Pages
- 19836-19841
- ISSN
- 0027-8424 (ISSN-L)
- 1091-6490
- OpenAlex
- W2102783132
- Cited by
- 323
- References
- 31
- FWCI
- 3.81
- Type
- journal article
- Language
- en
- Open access
- green
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- Feng, Y., Chen, M. H., Moskowitz, I. P., Mendonza, A. M., Vidali, L., Nakamura, F., Kwiatkowski, D. J., & Walsh, C. A. (2006). Filamin A (FLNA) is required for cell–cell contact in vascular development and cardiac morphogenesis. Proceedings of the National Academy of Sciences. https://doi.org/10.1073/pnas.0609628104
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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