The DOI matches its Crossref record; 3 of the 3 references it cites were found in a registry or an index.
RBP-J ( Rbpsuh ) is essential to maintain muscle progenitor cells and to generate satellite cells
Open accessAbstract
In the developing muscle, a pool of myogenic progenitor cells is formed and maintained. These resident progenitors provide a source of cells for muscle growth in development and generate satellite cells in the perinatal period. By the use of conditional mutagenesis in mice, we demonstrate here that the major mediator of Notch signaling, the transcription factor RBP-J , is essential to maintain this pool of progenitor cells in an undifferentiated state. In the absence of RBP-J , these cells undergo uncontrolled myogenic differentiation, leading to a depletion of the progenitor pool. This results in a lack of muscle growth in development and severe muscle hypotrophy. In addition, satellite cells are not formed late in fetal development in conditional RBP-J mutant mice. We conclude that RBP-J is required in the developing muscle to set aside proliferating progenitors and satellite cells.
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Cites
Rejuvenation of aged progenitor cells by exposure to a young systemic environment
Conboy, I. M., Conboy, M. J., Wagers, A. J., Girma, E. R., Weissman, I. L., & Rando, T. A. (2005) · Nature · doi:10.1038/nature03260 · Cited by 2,287
Notch-Mediated Restoration of Regenerative Potential to Aged Muscle
Conboy, I. M., Conboy, M. J., Smythe, G. M., & Rando, T. A. (2003) · Science · doi:10.1126/science.1087573 · Cited by 1,121
Notch–RBP-J signaling is involved in cell fate determination of marginal zone B cells
Tanigaki, K., Han, H., Yamamoto, N., Tashiro, K., Ikegawa, M., Kuroda, K., Suzuki, A., Nakano, T., & Honjo, T. (2002) · Nature Immunology · doi:10.1038/ni793 · Cited by 478
Cited by
Building Muscle: Molecular Regulation of Myogenesis
Bentzinger, C. F., Wang, Y. X., & Rudnicki, M. A. (2012) · Cold Spring Harbor Perspectives in Biology · doi:10.1101/cshperspect.a008342 · Cited by 1,195
Notch Signaling Is Necessary to Maintain Quiescence in Adult Muscle Stem Cells
Bjornson, C. R. R., Cheung, T. H., Liu, L., Tripathi, P. V., Steeper, K. M., & Rando, T. A. (2012) · Stem Cells · doi:10.1002/stem.773 · Cited by 598
Skeletal muscle satellite cells and adult myogenesis
Le Grand, F., & Rudnicki, M. A. (2007) · Current Opinion in Cell Biology · doi:10.1016/j.ceb.2007.09.012 · Cited by 544
Mourikis, P., Sambasivan, R., Castel, D., Rocheteau, P., Bizzarro, V., & Tajbakhsh, S. (2012) · Stem Cells · doi:10.1002/stem.775 · Cited by 526
Niche Regulation of Muscle Satellite Cell Self-Renewal and Differentiation
Kuang, S., Gillespie, M. A., & Rudnicki, M. A. (2008) · Cell Stem Cell · doi:10.1016/j.stem.2007.12.012 · Cited by 507
Metadata
- Authors
- Vasyutina, E., Lenhard, D. C., Wende, H., Erdmann, B., Epstein, J. A., & Birchmeier, C.
- Venue
- Proceedings of the National Academy of Sciences
- Published
- 2007-03-13
- Volume
- 104
- Issue
- 11
- Pages
- 4443-4448
- ISSN
- 0027-8424 (ISSN-L)
- 1091-6490
- OpenAlex
- W2008351799
- Cited by
- 240
- References
- 3
- FWCI
- 6.35
- Type
- journal article
- Language
- en
- Open access
- green
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- Vasyutina, E., Lenhard, D. C., Wende, H., Erdmann, B., Epstein, J. A., & Birchmeier, C. (2007). RBP-J ( Rbpsuh ) is essential to maintain muscle progenitor cells and to generate satellite cells. Proceedings of the National Academy of Sciences. https://doi.org/10.1073/pnas.0610647104
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