Redundant and unique roles of retinol dehydrogenases in the mouse retina

Highly abundant short-chain alcohol dehydrogenases (RDHs) in the retina were assumed to be involved in the recycling of 11- cis -retinal chromophore in the visual cycle. Mutations in human RDH genes are associated with Fundus albipunctatus , a mild form of night blindness ( RDH5 ) and an autosoma…