Palczewski, Krzysztof

Crystal Structure of Rhodopsin: A G Protein-Coupled Receptor

Palczewski, K., Kumasaka, T., Hori, T., Behnke, C. A., Motoshima, H., Fox, B. A., Trong, I. L., Teller, D. C., Okada, T., Stenkamp, R. E., et al. (2000) · Science

Receptor Mechanisms and SignalingPhotoreceptor and optogenetics research

Cited by 5,637

G Protein–Coupled Receptor Rhodopsin

Palczewski, K. (2006) · Annual Review of Biochemistry

Receptor Mechanisms and SignalingPhotoreceptor and optogenetics research

Cited by 764

Rhodopsin dimers in native disc membranes

Fotiadis, D., Liang, Y., Filipek, S., Saperstein, D. A., Engel, A., & Palczewski, K. (2003) · Nature

Receptor Mechanisms and SignalingPhotoreceptor and optogenetics research

Cited by 749

Engineered Virus-like Particles for Efficient in Vivo Delivery of Therapeutic Proteins

Banskota, S., Raguram, A., Suh, S., Du, S. W., Davis, J. R., Choi, E. H., Wang, X., Nielsen, S. C., Newby, G. A., Randolph, P. B., et al. (2022) · Cell

RNA Interference and Gene DeliveryCRISPR and Genetic Engineering

Cited by 668

Crystal structure of a photoactivated deprotonated intermediate of rhodopsin

Salom, D., Lodowski, D. T., Stenkamp, R. E., Trong, I. L., Golczak, M., Jastrzebska, B., Harris, T., Ballesteros, J. A., & Palczewski, K. (2006) · Proceedings of the National Academy of Sciences

Receptor Mechanisms and SignalingPhotoreceptor and optogenetics research

Cited by 442

Phagocytosis of Retinal Rod and Cone Photoreceptors

Kevany, B. M., & Palczewski, K. (2010) · Physiology

Retinal Development and DisordersRetinal Diseases and Treatments

Cited by 426

Diseases Caused by Defects in the Visual Cycle: Retinoids as Potential Therapeutic Agents

Travis, G. H., Golczak, M., Moise, A. R., & Palczewski, K. (2007) · Annual Review of Pharmacology and Toxicology

Retinal Development and DisordersRetinoids in leukemia and cellular processes

Cited by 419

Activation of rhodopsin: new insights from structural and biochemical studies

Okada, T., Ernst, O. P., Palczewski, K., & Hofmann, K. P. (2001) · Trends in Biochemical Sciences

Receptor Mechanisms and SignalingPhotoreceptor and optogenetics research

Cited by 413

Lecithin-retinol acyltransferase is essential for accumulation of all-trans-retinyl esters in the eye and in the liver

Batten, M. L., Imanishi, Y., Maeda, T., Tu, D. C., Moise, A. R., Bronson, D., Possin, D., Van Gelder, R. N., Baehr, W., & Palczewski, K. (2004) · Journal of Biological Chemistry

Retinal Development and DisordersRetinoids in leukemia and cellular processes

Cited by 368

Confronting Complexity: the Interlink of Phototransduction and Retinoid Metabolism in the Vertebrate Retina

McBee, J. K., Palczewski, K., Baehr, W., & Pepperberg, D. R. (2001) · Progress in Retinal and Eye Research

Retinal Development and DisordersPhotoreceptor and optogenetics research

Cited by 366

Chemistry of the Retinoid (Visual) Cycle

Kiser, P. D., Golczak, M., & Palczewski, K. (2014) · Chemical Reviews

Retinoids in leukemia and cellular processesPhotoreceptor and optogenetics research

Cited by 353

Retinopathy in Mice Induced by Disrupted All-trans-retinal Clearance

Maeda, A., Maeda, T., Golczak, M., & Palczewski, K. (2008) · Journal of Biological Chemistry

Retinal Development and DisordersRetinal Diseases and Treatments

Cited by 300

Retinoid absorption and storage is impaired in mice lacking lecithin:retinol acyltransferase (LRAT)

O'Byrne, S. M., Wongsiriroj, N., Libien, J., Vogel, S., Goldberg, I. J., Baehr, W., Palczewski, K., & Blaner, W. S. (2005) · Journal of Biological Chemistry

Retinoids in leukemia and cellular processesCholesterol and Lipid Metabolism

Cited by 296

Chemistry and Biology of Vision

Palczewski, K. (2012) · Journal of Biological Chemistry

Photoreceptor and optogenetics researchRetinal Development and Disorders

Cited by 289

Structure of cone photoreceptors

Mustafi, D., Engel, A. H., & Palczewski, K. (2009) · Progress in Retinal and Eye Research

Retinal Development and DisordersRetinal Diseases and Treatments

Cited by 275

G Protein-Coupled Receptor Rhodopsin: A Prospectus

Filipek, S., Stenkamp, R. E., Teller, D. C., & Palczewski, K. (2003) · Annual Review of Physiology

Receptor Mechanisms and SignalingPhotoreceptor and optogenetics research

Cited by 267

Rapid restoration of visual pigment and function with oral retinoid in a mouse model of childhood blindness

Van Hooser, J. P., Aleman, T. S., He, Y.-G., Cideciyan, A. V., Kuksa, V., Pittler, S. J., Stone, E. M., Jacobson, S. G., & Palczewski, K. (2000) · Proceedings of the National Academy of Sciences

Retinal Development and DisordersRetinoids in leukemia and cellular processes

Cited by 252

ISX is a retinoic acid-sensitive gatekeeper that controls intestinal β,β-carotene absorption and vitamin A production

Lobo, G. P., Hessel, S., Eichinger, A., Noy, N., Moise, A. R., Wyss, A., Palczewski, K., & Von Lintig, J. (2010) · The FASEB Journal

Retinoids in leukemia and cellular processesCholesterol and Lipid Metabolism

Cited by 248

Involvement of All-trans-retinal in Acute Light-induced Retinopathy of Mice

Maeda, A., Maeda, T., Golczak, M., Chou, S., Desai, A., Hoppel, C. L., Matsuyama, S., & Palczewski, K. (2009) · Journal of Biological Chemistry

Retinal Development and DisordersRetinal Diseases and Treatments

Cited by 248

Conserved waters mediate structural and functional activation of family A (rhodopsin-like) G protein-coupled receptors

Angel, T. E., Chance, M. R., & Palczewski, K. (2009) · Proceedings of the National Academy of Sciences

Receptor Mechanisms and SignalingPhotoreceptor and optogenetics research

Cited by 235

Mechanism of All-trans-retinal Toxicity with Implications for Stargardt Disease and Age-related Macular Degeneration

Chen, Y., Okano, K., Maeda, T., Chauhan, V., Golczak, M., Maeda, A., & Palczewski, K. (2012) · Journal of Biological Chemistry

Retinal Development and DisordersRetinal Diseases and Treatments

Cited by 229

Three-dimensional architecture of murine rod outer segments determined by cryoelectron tomography

Nickell, S., Park, P. S.-H., Baumeister, W., & Palczewski, K. (2007) · The Journal of Cell Biology

Advanced Electron Microscopy Techniques and ApplicationsRetinal Development and Disorders

Cited by 209

Structural waters define a functional channel mediating activation of the GPCR, rhodopsin

Angel, T. E., Gupta, S., Jastrzebska, B., Palczewski, K., & Chance, M. R. (2009) · Proceedings of the National Academy of Sciences

Receptor Mechanisms and SignalingPhotoreceptor and optogenetics research

Cited by 203

The ATP-Binding Cassette Transporter ABCA4: Structural and Functional Properties and Role in Retinal Disease

Tsybovsky, Y., Molday, R. S., & Palczewski, K. (2010) · Advances in Experimental Medicine and Biology

Retinal Development and DisordersDrug Transport and Resistance Mechanisms

Cited by 200