The DOI matches its Crossref record; 39 of the 39 references it cites were found in a registry or an index.
Smooth muscle cells in human coronary atherosclerosis can originate from cells administered at marrow transplantation
Open accessAbstract
Atherosclerosis is the major cause of adult mortality in the developed world, and a significant contributor to atherosclerotic plaque progression involves smooth muscle cell recruitment to the intima of the vessel wall. Controversy currently exists on the exact origin of these recruited cells. Here we use sex-mismatched bone marrow transplant subjects to show that smooth muscle cells throughout the atherosclerotic vessel wall can derive from donor bone marrow. We demonstrate extensive recruitment of these cells in diseased compared with undiseased segments and exclude cell–cell fusion events as a cause for this enrichment. These data have broad implications for our understanding of the cellular components of human atherosclerotic plaque and provide a potentially novel target for future diagnostic and therapeutic strategies.
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2 retracted
RETRACTED ARTICLE: Pluripotency of mesenchymal stem cells derived from adult marrow
Jiang, Y., Jahagirdar, B. N., Reinhardt, R. L., Schwartz, R. E., Keene, C. D., Ortiz-Gonzalez, X. R., Reyes, M., Lenvik, T., Lund, T., Blackstad, M., et al. (2002) · Nature · doi:10.1038/nature00870 · Cited by 5,518
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Reyes, M., Lund, T., Lenvik, T., Aguiar, D., Koodie, L., & Verfaillie, C. M. (2001) · Blood · doi:10.1182/blood.v98.9.2615 · Cited by 1,185
RetractedThe pathogenesis of atherosclerosis: a perspective for the 1990s
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Inflammation and Atherosclerosis
Libby, P., Ridker, P. M., & Maseri, A. (2002) · Circulation · doi:10.1161/hc0902.104353 · Cited by 7,724
Bone marrow cells regenerate infarcted myocardium
Orlic, D., Kajstura, J., Chimenti, S., Jakoniuk, I., Anderson, S. M., Li, B., Pickel, J., McKay, R., Nadal-Ginard, B., Bodine, D. M., et al. (2001) · Nature · doi:10.1038/35070587 · Cited by 5,155
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Bone marrow cells adopt the phenotype of other cells by spontaneous cell fusion
Terada, N., Hamazaki, T., Oka, M., Hoki, M., Mastalerz, D. M., Nakano, Y., Meyer, E. M., Morel, L., Petersen, B. E., & Scott, E. W. (2002) · Nature · doi:10.1038/nature730 · Cited by 1,999
Regeneration of ischemic cardiac muscle and vascular endothelium by adult stem cells
Jackson, K. A., Majka, S. M., Wang, H., Pocius, J., Hartley, C. J., Majesky, M. W., Entman, M. L., Michael, L. H., Hirschi, K. K., & Goodell, M. A. (2001) · Journal of Clinical Investigation · doi:10.1172/jci12150 · Cited by 1,960
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Cited by
Vascular smooth muscle cells in atherosclerosis
Bennett, M. R., Sinha, S., & Owens, G. K. (2016) · Circulation Research · doi:10.1161/circresaha.115.306361 · Cited by 2,179
Pathogenesis of atherosclerosis
Falk, E. (2006) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2005.09.068 · Cited by 1,447
Shankman, L. S., Gomez, D., Cherepanova, O. A., Salmon, M., Alencar, G. F., Haskins, R. M., Swiatlowska, P., Newman, A. A. C., Greene, E. S., Straub, A. C., et al. (2015) · Nature Medicine · doi:10.1038/nm.3866 · Cited by 1,218
Vascular smooth muscle cells in atherosclerosis
Basatemur, G. L., Jørgensen, H. F., Clarke, M. C. H., Bennett, M. R., & Mallat, Z. (2019) · Nature Reviews Cardiology · doi:10.1038/s41569-019-0227-9 · Cited by 1,099
Recent insights into the cellular biology of atherosclerosis
Tabas, I., García-Cardeña, G., & Owens, G. K. (2015) · Journal of Cell Biology · doi:10.1083/jcb.201412052 · Cited by 1,016
Metadata
- Authors
- Caplice, N. M., Bunch, T. J., Stalboerger, P. G., Wang, S., Simper, D., Miller, D. V., Russell, S. J., Litzow, M. R., & Edwards, W. D.
- Venue
- Proceedings of the National Academy of Sciences
- Published
- 2003-03-28
- Volume
- 100
- Issue
- 8
- Pages
- 4754-4759
- ISSN
- 0027-8424 (ISSN-L)
- 1091-6490
- OpenAlex
- W2007439146
- Cited by
- 340
- References
- 39
- FWCI
- 10.09
- Type
- journal article
- Language
- en
- Open access
- green
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- CoChat. (2026). Citation check: Smooth muscle cells in human coronary atherosclerosis can originate from cells administered at marrow transplantation. https://app.cochat.ai/papers/10.1073/pnas.0730743100
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- Caplice, N. M., Bunch, T. J., Stalboerger, P. G., Wang, S., Simper, D., Miller, D. V., Russell, S. J., Litzow, M. R., & Edwards, W. D. (2003). Smooth muscle cells in human coronary atherosclerosis can originate from cells administered at marrow transplantation. Proceedings of the National Academy of Sciences. https://doi.org/10.1073/pnas.0730743100
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.