Nonequilibrium generation of information in copolymerization processes
Open accessAbstract
We consider general fluctuating copolymerization processes, with or without underlying templates. The dissipation associated with these nonequilibrium processes turns out to be closely related to the information generated. This shows in particular how information acquisition results from the interplay between stored patterns and dynamical evolution in nonequilibrium environments. In addition, we apply these results to the process of DNA replication.
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The mean error rate of replication increases as the reaction condition approaches equilibrium, contributing to entropy production.
“The mean error rate of replication increases as the reaction condition approaches equilibrium, contributing to entropy production [32].”
From Thermodynamic Basis for the Emergence of Genomes during Prebiotic Evolution (2012) · cites this paper as [32]
Cites
An extracellular Darwinian experiment with a self-duplicating nucleic acid molecule.
Mills, D. R., Peterson, R. L., & Spiegelman, S. (1967) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.58.1.217 · Cited by 648 · see citing works
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Stochastic thermodynamics, fluctuation theorems and molecular machines
Seifert, U. (2012) · Reports on Progress in Physics · doi:10.1088/0034-4885/75/12/126001 · Cited by 3,300 · see citing works
Origins of life: a problem for physics, a key issues review
Walker, S. I. (2017) · Reports on Progress in Physics · doi:10.1088/1361-6633/aa7804 · Cited by 94 · see citing works
The thermodynamic efficiency of computations made in cells across the range of life
Kempes, C. P., Wolpert, D., Cohen, Z., & Pérez-Mercader, J. (2017) · Philosophical Transactions of the Royal Society A: Mathematical, Physical and Engineering Sciences · doi:10.1098/rsta.2016.0343 · Cited by 68 · see citing works
Nonequilibrium phase transitions associated with dna replication.
Woo, H.-J., & Wallqvist, A. (2011) · Physical Review Letters · doi:10.1103/physrevlett.106.060601 · Cited by 11 · see citing works
Thermodynamic Basis for the Emergence of Genomes during Prebiotic Evolution
Woo, H.-J., Vijaya Satya, R., & Reifman, J. (2012) · PLoS Computational Biology · doi:10.1371/journal.pcbi.1002534 · Cited by 6 · see citing works
“We introduce the reduced distribution [32]”
BackgroundInfluential
- Authors
- Andrieux, D., & Gaspard, P.
- Affiliations
- Université Libre de Bruxelles (BE)
- Venue
- Proceedings of the National Academy of Sciences
- Publisher
- National Academy of Sciences
- Published
- 2008-07-15
- Volume
- 105
- Issue
- 28
- Pages
- 9516-9521
- ISSN
- 0027-8424 (ISSN-L)
- 1091-6490
- PMC
- PMC2474480
- OpenAlex
- W2019080025
- Cited by
- 182
- References
- 1
- Citations by year
- 2026: 8 · 2025: 11 · 2024: 6 · 2023: 6 · 2022: 10 · 2021: 15 · 2020: 5 · 2019: 11 · 2018: 7 · 2017: 25 · 2016: 15 · 2015: 18 · 2014: 15 · 2013: 13 · 2012: 6
- FWCI
- 2.84
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- Proceedings of the National Academy of Sciences (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- Dépôt institutionnel de l'Université libre de Bruxelles (Université Libre de Bruxelles) (submittedVersion)
- Topics
- Physical Sciences › Physics and Astronomy › Statistical and Nonlinear Physics › Advanced Thermodynamics and Statistical Mechanics
- Physical Sciences › Computer Science › Computational Theory and Mathematics › Cellular Automata and Applications
- Physical Sciences › Physics and Astronomy › Astronomy and Astrophysics › Origins and Evolution of Life
- Keywords
- copolymerization, information generation, nonequilibrium processes, energy dissipation, template synthesis, DNA replication, information acquisition
- MeSH terms
- DNA Replication, Genetic Code, Stochastic Processes, Templates, Genetic, Thermodynamics, Models, Statistical, Entropy
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