The DOI matches its Crossref record; 3 of the 3 references it cites were found in a registry or an index.
Age-related top-down suppression deficit in the early stages of cortical visual memory processing
Open accessAbstract
In this study, electroencephalography (EEG) was used to examine the relationship between two leading hypotheses of cognitive aging, the inhibitory deficit and the processing speed hypothesis. We show that older adults exhibit a selective deficit in suppressing task-irrelevant information during visual working memory encoding, but only in the early stages of visual processing. Thus, the employment of suppressive mechanisms are not abolished with aging but rather delayed in time, revealing a decline in processing speed that is selective for the inhibition of irrelevant information. EEG spectral analysis of signals from frontal regions suggests that this results from excessive attention to distracting information early in the time course of viewing irrelevant stimuli. Subdividing the older population based on working memory performance revealed that impaired suppression of distracting information early in the visual processing stream is associated with poorer memory of task-relevant information. Thus, these data reconcile two cognitive aging hypotheses by revealing that an interaction of deficits in inhibition and processing speed contributes to age-related cognitive impairment.
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Cites
The processing-speed theory of adult age differences in cognition
Salthouse, T. A. (1996) · Psychological Review · doi:10.1037/0033-295x.103.3.403 · Cited by 5,902 · cited 1×
“Two of the leading cognitive aging hypotheses are the ‘‘processing speed hypothesis,’’ in which performance deficits are attributed to a decline in processing speed (2), and the ‘‘inhibitory deficit hypothesis,’’ which proposes that impairment in diverse cognitive abilities are the result of an inability to reduce int…”
BackgroundTop-down suppression deficit underlies working memory impairment in normal aging
Gazzaley, A., Cooney, J. W., Rissman, J., & D'Esposito, M. (2005) · Nature Neuroscience · doi:10.1038/nn1543 · Cited by 934
Self-citationPrefrontal modulation of visual processing in humans
Barceló, F., Suwazono, S., & Knight, R. T. (2000) · Nature Neuroscience · doi:10.1038/73975 · Cited by 374
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Self-citationTop-down modulation: bridging selective attention and working memory
Gazzaley, A., & Nobre, A. C. (2012) · Trends in Cognitive Sciences · doi:10.1016/j.tics.2011.11.014 · Cited by 1,404
The role of default network deactivation in cognition and disease
Anticevic, A., Cole, M. W., Murray, J. D., Corlett, P. R., Wang, X.-J., & Krystal, J. H. (2012) · Trends in Cognitive Sciences · doi:10.1016/j.tics.2012.10.008 · Cited by 978
Intelligence and neural efficiency
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Metadata
- Authors
- Gazzaley, A., Clapp, W., Kelley, J., McEvoy, K., Knight, R. T., & D'Esposito, M.
- Venue
- Proceedings of the National Academy of Sciences
- Published
- 2008-09-02
- Volume
- 105
- Issue
- 35
- Pages
- 13122-13126
- ISSN
- 0027-8424 (ISSN-L)
- 1091-6490
- OpenAlex
- W2078377691
- Cited by
- 452
- References
- 3
- FWCI
- 12.99
- Type
- journal article
- Language
- en
- Open access
- green
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