The DOI matches its Crossref record; 3 of the 3 references it cites were found in a registry or an index.
RNA tertiary interactions in the large ribosomal subunit: The A-minor motif
Open accessAbstract
Analysis of the 2.4-Å resolution crystal structure of the large ribosomal subunit from Haloarcula marismortui reveals the existence of an abundant and ubiquitous structural motif that stabilizes RNA tertiary and quaternary structures. This motif is termed the A-minor motif, because it involves the insertion of the smooth, minor groove edges of adenines into the minor groove of neighboring helices, preferentially at C-G base pairs, where they form hydrogen bonds with one or both of the 2′ OHs of those pairs. A-minor motifs stabilize contacts between RNA helices, interactions between loops and helices, and the conformations of junctions and tight turns. The interactions between the 3′ terminal adenine of tRNAs bound in either the A site or the P site with 23S rRNA are examples of functionally significant A-minor interactions. The A-minor motif is by far the most abundant tertiary structure interaction in the large ribosomal subunit; 186 adenines in 23S and 5S rRNA participate, 68 of which are conserved. It may prove to be the universally most important long-range interaction in large RNA structures.
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Cites
Structure of the 30S ribosomal subunit
Wimberly, B. T., Brodersen, D. E., Clemons, W. M., Morgan-Warren, R. J., Carter, A. P., Vonrhein, C., Hartsch, T., & Ramakrishnan, V. (2000) · Nature · doi:10.1038/35030006 · Cited by 2,035
Control of memory formation through regulated expression of a CaMKII transgene
Mayford, M., Bach, M. E., Huang, Y.-Y., Wang, L., Hawkins, R. D., & Kandel, E. R. (1996) · Science · doi:10.1126/science.274.5293.1678 · Cited by 1,550
Structure of Functionally Activated Small Ribosomal Subunit at 3.3 Å Resolution
Schluenzen, F., Tocilj, A., Zarivach, R., Harms, J., Gluehmann, M., Janell, D., Bashan, A., Bartels, H., Agmon, I., Franceschi, F., et al. (2000) · Cell · doi:10.1016/s0092-8674(00)00084-2 · Cited by 979
Cited by
Ribosome Structure and the Mechanism of Translation
Ramakrishnan, V. (2002) · Cell · doi:10.1016/s0092-8674(02)00619-0 · Cited by 938
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Leontis, N. B. (2002) · Nucleic Acids Research · doi:10.1093/nar/gkf481 · Cited by 796
Selection of tRNA by the Ribosome Requires a Transition from an Open to a Closed Form
Ogle, J. M., Murphy, F. V., Tarry, M. J., & Ramakrishnan, V. (2002) · Cell · doi:10.1016/s0092-8674(02)01086-3 · Cited by 663
Initiation of Protein Synthesis in Bacteria
Laursen, B. S., Sørensen, H. P., Mortensen, K. K., & Sperling-Petersen, H. U. (2005) · Microbiology and Molecular Biology Reviews · doi:10.1128/mmbr.69.1.101-123.2005 · Cited by 616
Nucleic Acid Based Molecular Devices
Krishnan, Y., & Simmel, F. C. (2011) · Angewandte Chemie International Edition · doi:10.1002/anie.200907223 · Cited by 572
Metadata
- Authors
- Nissen, P., Ippolito, J. A., Ban, N., Moore, P. B., & Steitz, T. A.
- Venue
- Proceedings of the National Academy of Sciences
- Published
- 2001-04-10
- Volume
- 98
- Issue
- 9
- Pages
- 4899-4903
- ISSN
- 0027-8424 (ISSN-L)
- 1091-6490
- OpenAlex
- W2013902881
- Cited by
- 662
- References
- 3
- FWCI
- 10.75
- Type
- journal article
- Language
- en
- Open access
- green
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- Nissen, P., Ippolito, J. A., Ban, N., Moore, P. B., & Steitz, T. A. (2001). RNA tertiary interactions in the large ribosomal subunit: The A-minor motif. Proceedings of the National Academy of Sciences. https://doi.org/10.1073/pnas.081082398
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