The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.
Selective interaction of plant homeodomain proteins mediates high DNA-binding affinity
Open accessAbstract
Understanding molecular mechanisms that control cell fate in the shoot apical meristem is a fundamental question in plant development. Genetic and molecular studies demonstrate that maize KNOTTED1 (KN1) of the TALE (3-aa acid loop extension) class of homeodomain (HD) proteins is involved in shoot apical meristem function. We show that KN1 interacts with knotted interacting protein (KIP), a BEL1-like TALE HD protein. Interaction between KN1 and KIP is mediated by conserved domains in the N termini of both proteins. The KN1 DNA-binding sequence, TGACAG(G/C)T, was biochemically identified, and in vitro DNA-binding assays show that individually KN1 and the HD of KIP bind specifically to this motif with low affinity. The KN1–KIP complex, however, binds specifically to this DNA-binding motif with high affinity, indicating that the association of KN1 and KIP may function in transcriptional regulation.
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Cites
A member of the KNOTTED class of homeodomain proteins encoded by the STM gene of Arabidopsis
Long, J. A., Moan, E. I., Medford, J. I., & Barton, M. K. (1996) · Nature · doi:10.1038/379066a0 · Cited by 1,537
A regulatory hierarchy for cell specialization in yeast
Herskowitz, I. (1989) · Nature · doi:10.1038/342749a0 · Cited by 590
Cited by
Tian, F., Bradbury, P. J., Brown, P. J., Hung, H., Sun, Q., Flint-Garcia, S., Rocheford, T. R., McMullen, M. D., Holland, J. B., & Buckler, E. S. (2011) · Nature Genetics · doi:10.1038/ng.746 · Cited by 1,043
KNOX genes: versatile regulators of plant development and diversity
Hay, A., & Tsiantis, M. (2010) · Development · doi:10.1242/dev.030049 · Cited by 592
THE ROLE OF KNOX GENES IN PLANT DEVELOPMENT
Hake, S., Smith, H. M. S., Holtan, H., Magnani, E., Mele, G., & Ramirez, J. (2004) · Annual Review of Cell and Developmental Biology · doi:10.1146/annurev.cellbio.20.031803.093824 · Cited by 458
Self-citationA Comprehensive Classification and Evolutionary Analysis of Plant Homeobox Genes
Mukherjee, K., Brocchieri, L., & Burglin, T. R. (2009) · Molecular Biology and Evolution · doi:10.1093/molbev/msp201 · Cited by 448
Rosin, F. M., Hart, J. K., Horner, H. T., Davies, P. J., & Hannapel, D. J. (2003) · Plant Physiology · doi:10.1104/pp.102.015560 · Cited by 179
Metadata
- Authors
- Smith, H. M. S., Boschke, I., & Hake, S.
- Venue
- Proceedings of the National Academy of Sciences
- Published
- 2002-07
- Volume
- 99
- Issue
- 14
- Pages
- 9579-9584
- ISSN
- 0027-8424 (ISSN-L)
- 1091-6490
- OpenAlex
- W2095050389
- Cited by
- 174
- References
- 2
- FWCI
- 13.08
- Type
- journal article
- Language
- en
- Open access
- green
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- Smith, H. M. S., Boschke, I., & Hake, S. (2002). Selective interaction of plant homeodomain proteins mediates high DNA-binding affinity. Proceedings of the National Academy of Sciences. https://doi.org/10.1073/pnas.092271599
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