The DOI matches its Crossref record; 27 of the 27 references it cites were found in a registry or an index.
Control of salicylic acid synthesis and systemic acquired resistance by two members of a plant-specific family of transcription factors
Open accessAbstract
Salicylic acid (SA) is a defense hormone required for both local and systemic acquired resistance (SAR) in plants. Pathogen infections induce SA synthesis through up-regulating the expression of Isochorismate Synthase 1 ( ICS1 ), which encodes a key enzyme in SA production. Here we report that both SAR Deficient 1 (SARD1) and CBP60g are key regulators for ICS1 induction and SA synthesis. Whereas knocking out SARD1 compromises basal resistance and SAR, overexpression of SARD1 constitutively activates defense responses. In the sard1-1 cbp60g-1 double mutant, pathogen-induced ICS1 up-regulation and SA synthesis are blocked in both local and systemic leaves, resulting in compromised basal resistance and loss of SAR. Electrophoretic mobility shift assays showed that SARD1 and CBP60g represent a plant-specific family of DNA-binding proteins. Both proteins are recruited to the promoter of ICS1 in response to pathogen infections, suggesting that they control SA synthesis by regulating ICS1 at the transcriptional level.
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Cites
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Salicylic acid, a multifaceted hormone to combat disease
Vlot, A. C., Dempsey, D. A., & Klessig, D. F. (2009) · Annual Review of Phytopathology · doi:10.1146/annurev.phyto.050908.135202 · Cited by 2,568
Isochorismate synthase is required to synthesize salicylic acid for plant defence
Wildermuth, M. C., Dewdney, J., Wu, G., & Ausubel, F. M. (2001) · Nature · doi:10.1038/35107108 · Cited by 2,357
Requirement of Salicylic Acid for the Induction of Systemic Acquired Resistance
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Inducers of Plant Systemic Acquired Resistance Regulate NPR1 Function through Redox Changes
Mou, Z., Fan, W., & Dong, X. (2003) · Cell · doi:10.1016/s0092-8674(03)00429-x · Cited by 1,568
Salicylic Acid: A Likely Endogenous Signal in the Resistance Response of Tobacco to Viral Infection
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Cited by
Systemic Acquired Resistance: Turning Local Infection into Global Defense
Fu, Z. Q., & Dong, X. (2013) · Annual Review of Plant Biology · doi:10.1146/annurev-arplant-042811-105606 · Cited by 1,524
Thirty years of resistance: Zig-zag through the plant immune system
Ngou, B. P. M., Ding, P., & Jones, J. D. G. (2022) · The Plant Cell · doi:10.1093/plcell/koac041 · Cited by 961
Self-citationCoping with Stresses: Roles of Calcium- and Calcium/Calmodulin-Regulated Gene Expression
Reddy, A. S. N., Ali, G. S., Celesnik, H., & Day, I. S. (2011) · The Plant Cell · doi:10.1105/tpc.111.084988 · Cited by 784
Salicylic Acid: Biosynthesis and Signaling
Peng, Y., Yang, J., Li, X., & Zhang, Y. (2021) · Annual Review of Plant Biology · doi:10.1146/annurev-arplant-081320-092855 · Cited by 560
Self-citationNgou, B. P. M., Jones, J. D. G., & Ding, P. (2022) · Trends in Plant Science · doi:10.1016/j.tplants.2021.08.012 · Cited by 384
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Metadata
- Authors
- Zhang, Y., Xu, S., Ding, P., Wang, D., Cheng, Y. T., He, J., Gao, M., Xu, F., Li, Y., Zhu, Z., Li, X., & Zhang, Y.
- Venue
- Proceedings of the National Academy of Sciences
- Published
- 2010-10-04
- Volume
- 107
- Issue
- 42
- Pages
- 18220-18225
- ISSN
- 0027-8424 (ISSN-L)
- 1091-6490
- OpenAlex
- W2079671481
- Cited by
- 454
- References
- 27
- FWCI
- 12.73
- Type
- journal article
- Language
- en
- Open access
- green
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