Cited by 364Birth, Development, and HealthCognitive Abilities and TestingDementia and Cognitive Impairment Research

The DOI matches its Crossref record; 39 of the 39 references it cites were found in a registry or an index.

Prenatal undernutrition and cognitive function in late adulthood

Open access

de Rooij, Susanne R., Wouters, Hans, Yonker, Julie E., Painter, Rebecca C., Roseboom, Tessa J.·2010·Proceedings of the National Academy of Sciences

DOI 10.1073/pnas.1009459107PMC PMC2947913

Open this paper in CoChat — free account

Abstract

At the end of World War II, a severe 5-mo famine struck the cities in the western part of The Netherlands. At its peak, the rations dropped to as low as 400 calories per day. In 1972, cognitive performance in 19-y-old male conscripts was reported not to have been affected by exposure to the famine before birth. In the present study, we show that cognitive function in later life does seem affected by prenatal undernutrition. We found that at age 56 to 59, men and women exposed to famine during the early stage of gestation performed worse on a selective attention task, a cognitive ability that usually declines with increasing age. We hypothesize that this decline may be an early manifestation of an accelerated cognitive aging process.

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

Integrity signals

Registry

Crossref · 10.1073/pnas.1009459107

Cites

39 of 39 references verified0 citation errors · 0 not checkable

Statistics

Claims the paper makes

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Self-check

Percentages, sums and reported differences re-computed from the paper’s own numbers.

The self-check needs the paper’s full text.

The Hospital Anxiety and Depression Scale
Zigmond, A. S., & Snaith, R. P. (1983) · Acta Psychiatrica Scandinavica · doi:10.1111/j.1600-0447.1983.tb09716.x · Cited by 47,139
Studies of interference in serial verbal reactions
Stroop, J. R. (1935) · Journal of Experimental Psychology · doi:10.1037/h0054651 · Cited by 18,622
Half a century of research on the Stroop effect: An integrative review.
MacLeod, C. M. (1991) · Psychological Bulletin · doi:10.1037/0033-2909.109.2.163 · Cited by 5,500
Extending Healthy Life Span—From Yeast to Humans
Fontana, L., Partridge, L., & Longo, V. D. (2010) · Science · doi:10.1126/science.1172539 · Cited by 3,023
Glucose tolerance in adults after prenatal exposure to famine
Ravelli, A., van der Meulen, J., Michels, R., Osmond, C., Barker, D., Hales, C., & Bleker, O. (1998) · The Lancet · doi:10.1016/s0140-6736(97)07244-9 · Cited by 1,606
Obesity at the age of 50 y in men and women exposed to famine prenatally
Ravelli, A. C. J., van der Meulen, J., Osmond, C., Barker, D. J. P., & Bleker, O. P. (1999) · American Journal of Clinical Nutrition · doi:10.1093/ajcn/70.5.811 · Cited by 1,165
The Dutch Famine and Its Long-Term Consequences for Adult Health
Roseboom, T., de Rooij, S., & Painter, R. (2006) · Early Human Development · doi:10.1016/j.earlhumdev.2006.07.001 · Cited by 1,137
Self-citation
Cerebral white matter lesions, vascular risk factors, and cognitive function in a population‐based study
Breteler, M. M. B., Swieten, J. C. V., Bots, M. L., Grobbee, D. E., Claus, J. J., Hout, J. H. W. V. D., van Harskamp, F., Tanghe, H. L. J., de Jong, P. T. V. M., van Gijn, J., et al. (1994) · Neurology · doi:10.1212/wnl.44.7.1246 · Cited by 1,006
Maternal seafood consumption in pregnancy and neurodevelopmental outcomes in childhood (ALSPAC study): an observational cohort study
Hibbeln, J. R., Davis, J. M., Steer, C., Emmett, P., Rogers, I., Williams, C., & Golding, J. (2007) · The Lancet · doi:10.1016/s0140-6736(07)60277-3 · Cited by 987
Alzheimer Disease as a Vascular Disorder
de la Torre, J. C. (2002) · Stroke · doi:10.1161/01.str.0000014421.15948.67 · Cited by 852

Flagged first, then by citations

Show all 38 references

Research works printed but not linked: 4

; National Bureau of Food Distribution in Wartime Rations per day period 1 Oct 1944– 22 July 1945 for the western Netherlands, (Translated from the Dutch). (1945).
GCE Burger, HR Sandstead, JC Drummond Malnutrition and Starvation in Western Netherlands, September 1944 to July 1945. Part I and II (General State Printing Office, The Hague, 1948).
B Bakker, I Sieben, International Socio-Economic Index of occupational status (1992). Soc Wetenschappen 40, 1–22, (Translated from the Dutch). (1997).
A Heim AH4 Group Test of General Intelligence (NFER-Nelson Publishing Company Ltd, Windsor, United Kingdom, 1970).

Sorted by citations

Items 101–200 of 361

Prenatal famine exposure and mental health in later midlife
van den Broek, T., & Fleischmann, M. S. (2017) · Aging & Mental Health · doi:10.1080/13607863.2017.1402293 · Cited by 35
Prenatal malnutrition and adult cognitive impairment: a natural experiment from the 1959–1961 Chinese famine
He, P., Liu, L., Salas, J. M. I., Guo, C., Cheng, Y., Chen, G., & Zheng, X. (2018) · British Journal Of Nutrition · doi:10.1017/s0007114518000958 · Cited by 35
Early-Life Exposure to the Chinese Famine and Risk of Cognitive Decline
Rong, H., Lai, X., Mahmoudi, E., & Fang, H. (2019) · Journal of Clinical Medicine · doi:10.3390/jcm8040484 · Cited by 35
Prenatal Undernutrition and Physical Function and Frailty at the Age of 68 Years: The Dutch Famine Birth Cohort Study
Bleker, L. S., de Rooij, S. R., Painter, R. C., van der Velde, N., & Roseboom, T. J. (2016) · The Journals of Gerontology Series A · doi:10.1093/gerona/glw081 · Cited by 34
Self-citation
Nutritional Regulation of Embryonic Survival, Growth, and Development
Reynolds, L. P., McLean, K. J., McCarthy, K. L., Diniz, W. J. S., Menezes, A. C. B., Forcherio, J. C., Scott, R. R., Borowicz, P. P., Ward, A. K. K., Dahlen, C. R., et al. (2021) · Advances in experimental medicine and biology · doi:10.1007/978-3-030-85686-1_4 · Cited by 34
Epigenetics and Early Life Stress: Experimental Brood Size Affects DNA Methylation in Great Tits (Parus major)
Sepers, B., Erven, J. A. M., Gawehns, F., Laine, V. N., & van Oers, K. (2021) · Frontiers in Ecology and Evolution · doi:10.3389/fevo.2021.609061 · Cited by 33
Environmental Exposures around Conception: Developmental Pathways Leading to Lifetime Disease Risk
Fleming, T. P., Sun, C., Denisenko, O. N., Caetano, L., Aljahdali, A. R., Gould, J. M., & Khurana, P. (2021) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph18179380 · Cited by 31
Disposable Soma Theory and the Evolution of Maternal Effects on Ageing
van den Heuvel, J., English, S., & Uller, T. (2016) · PLoS ONE · doi:10.1371/journal.pone.0145544 · Cited by 33
Childhood Adversity and Adult Physical Health
Ehrlich, K. B., Miller, G. E., & Chen, E. (2016) · Wiley eBooks · doi:10.1002/9781119125556.devpsy401 · Cited by 32
Cerebral Small Vessel Disease: Early-Life Antecedents and Long-Term Implications for the Brain, Aging, Stroke, and Dementia
Backhouse, E. V., Boardman, J. P., & Wardlaw, J. M. (2023) · Hypertension · doi:10.1161/hypertensionaha.122.19940 · Cited by 31
Enhanced Deficits in Long-Term Potentiation in the Adult Dentate Gyrus with 2nd Trimester Ethanol Consumption
Helfer, J. L., White, E. R., & Christie, B. R. (2012) · PLoS ONE · doi:10.1371/journal.pone.0051344 · Cited by 31
The Barker Hypothesis
Edwards, M. J. (2017) · Springer eBooks · doi:10.1007/978-3-319-40007-5_71-1 · Cited by 36
Examining developmental plasticity in the skeletal system through a sensitive developmental windows framework
McPherson, C. B. (2021) · American Journal of Physical Anthropology · doi:10.1002/ajpa.24338 · Cited by 31
Nutritional Programming: History, Hypotheses, and the Role of Prenatal Factors in the Prevention of Metabolic Diseases—A Narrative Review
Michońska, I., Łuszczki, E., Zielińska, M., Oleksy, Ł., Stolarczyk, A., & Dereń, K. (2022) · Nutrients · doi:10.3390/nu14204422 · Cited by 32
Epigenetic vulnerability and the environmental influence on health
Gomes, M. V., & Pelosi, G. G. (2013) · Experimental Biology and Medicine · doi:10.1177/1535370213490630 · Cited by 29
In vivo biomarkers of structural and functional brain development and aging in humans
Franke, K., Bublak, P., Hoyer, D., Billiet, T., Gaser, C., Witte, O. W., & Schwab, M. G. (2020) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2017.11.002 · Cited by 29
Competition for Materno-Fetal Resource Partitioning in a Rabbit Model of Undernourished Pregnancy
López‐Tello, J., Arias‐Álvarez, M., Martínez, M. D. L. Á. J., García-García, R. M., Rodríguez, M., Lorenzo, P. L., Bermejo‐Poza, R., Gonzalez‐Bulnes, A., & Rebollar, P. G. (2017) · PLoS ONE · doi:10.1371/journal.pone.0169194 · Cited by 28
Charting Alzheimer’s Disease and Dementia: Epidemiological Insights, Risk Factors and Prevention Pathways
Contador, I., Buch-Vicente, B., del Ser, T., Velasco, S. L., Villarejo‐Galende, A., Benito‐León, J., & Bermejo‐Pareja, F. (2024) · Journal of Clinical Medicine · doi:10.3390/jcm13144100 · Cited by 31
Birth weight and cognitive ability in adulthood: A systematic review and meta-analysis
Grove, B. J., Lim, S. J., Galé, C. R., & Shenkin, S. D. (2017) · Intelligence · doi:10.1016/j.intell.2017.02.001 · Cited by 28
Comparison of cricket diet with peanut-based and milk-based diets in the recovery from protein malnutrition in mice and the impact on growth, metabolism and immune function
Bergmans, R. S., Nikodémová, M., Stull, V. J., Redding, A., & Malecki, K. M. C. (2020) · PLoS ONE · doi:10.1371/journal.pone.0234559 · Cited by 28
Late-life brain perfusion after prenatal famine exposure
de Rooij, S. R., Mutsaerts, H. J. M. M., Petr, J., Asllani, I., Caan, M. W. A., Groot, P. F. C., Nederveen, A. J., Schwab, M. G., & Roseboom, T. J. (2019) · Neurobiology of Aging · doi:10.1016/j.neurobiolaging.2019.06.012 · Cited by 27
Self-citation
Identification of epigenetic memory candidates associated with gestational age at birth through analysis of methylome and transcriptional data
Kashima, K., Kawai, T., Nishimura, R., Shiwa, Y., Urayama, K. Y., Kamura, H., Takeda, K., Aoto, S., Ito, A. M., Matsubara, K., et al. (2021) · Scientific Reports · doi:10.1038/s41598-021-83016-3 · Cited by 26
The Response of Child Nutrition to Changes in Income: Linking Biology with Economics
Alderman, H. (2012) · CESifo Economic Studies · doi:10.1093/cesifo/ifs012 · Cited by 26
Effects of Nutrition on Maternal Health, Fetal Development, and Perinatal Outcomes
Apostolopoulou, A., Tranidou, A., Tsakiridis, I. G., Magriplis, E., Dagklis, T., & Chourdakis, M. (2024) · Nutrients · doi:10.3390/nu16030375 · Cited by 26
The role of nutrition and gut microbiome in childhood brain development and behavior
Jiang, Y., & Li, Y. (2025) · Frontiers in Nutrition · doi:10.3389/fnut.2025.1590172 · Cited by 35
The developmental origins of ageing: study protocol for the Dutch famine birth cohort study on ageing
de Rooij, S. R., & Roseboom, T. J. (2013) · BMJ Open · doi:10.1136/bmjopen-2013-003167 · Cited by 24
Self-citation
Maternal PTSD following Exposure to the Wenchuan Earthquake Is Associated with Impaired Mental Development of Children
Cai, D., Zhu, Z., Sun, H., Qi, Y., Xing, L., Zhao, X., Wan, Q., Su, Q., & Li, H. (2017) · PLoS ONE · doi:10.1371/journal.pone.0168747 · Cited by 22
Human Capital and Shocks: Evidence on Education, Health and Nutrition
Frankenberg, E., & Thomas, D. (2017) · National Bureau of Economic Research · doi:10.3386/w23347 · Cited by 22
The Origins of Cognitive Skills and Non-Cognitive Skills: The Long-Term Effect of In-Utero Rainfall Shocks in India
Chang, G., Favara, M., & Novella, R. (2020) · Economics & Human Biology · doi:10.1016/j.ehb.2021.101089 · Cited by 21
Shaping the risk for late-life neurodegenerative disease: A systematic review on prenatal risk factors for Alzheimer’s disease-related volumetric brain biomarkers
Boots, A., Wiegersma, A. M., Vali, Y., den Hof, M. V., Langendam, M. W., Limpens, J., Backhouse, E. V., Shenkin, S. D., Wardlaw, J. M., Roseboom, T. J., et al. (2023) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2022.105019 · Cited by 22
Self-citation
Epigenetic mechanisms linking early-life adversities and mental health
Cánepa, E. T., & Berardino, B. G. (2024) · Biochemical Journal · doi:10.1042/bcj20230306 · Cited by 22
The Correlation between Early Stages of Life Exposed to Chinese Famine and Cognitive Decline in Adulthood: Nutrition of Adulthood Plays an Important Role in the Link?
Rong, H., Xi, Y., An, Y., Tao, L., Zhang, X., Yu, H., Wang, Y., Qin, Z., & Xiao, R. (2018) · Frontiers in Aging Neuroscience · doi:10.3389/fnagi.2017.00444 · Cited by 21
Prenatal Exposure to Famine and Risk for Development of Psychopathology in Adulthood: A Meta-Analysis
Dana, K., Koenig, S., Motter, J. N., Zhang, W., Linaris, M., Brumberg, J. C., & Nomura, Y. (2019) · Journal of Psychiatry and Psychiatric Disorders · doi:10.26502/jppd.2572-519x0077 · Cited by 20
Prenatal exposure to the Dutch famine is associated with more self-perceived cognitive problems at 72 years of age
Wiegersma, A. M., Boots, A., Roseboom, T. J., & de Rooij, S. R. (2022) · BMC Geriatrics · doi:10.1186/s12877-022-02820-2 · Cited by 20
Self-citation
Evaluating the association between placenta DNA methylation and cognitive functions in the offspring
Cosín‐Tomás, M., Díez-Ahijado, L., Cilleros‐Portet, A., Fernández, M. F., Fernández, M. F., Guxens, M., Júlvez, J., Llop, S., López-Espinosa, M.-J., Subiza, M., et al. (2024) · Translational Psychiatry · doi:10.1038/s41398-024-03094-5 · Cited by 20
On the relationship between economic conditions around the time of birth and late life cognitive abilities: Evidence from Taiwan
Chen, W. (2016) · Economics & Human Biology · doi:10.1016/j.ehb.2016.04.001 · Cited by 20
The educational impact of shocks in utero: Evidence from Rwanda
Bundervoet, T., & Fransen, S. (2018) · Economics & Human Biology · doi:10.1016/j.ehb.2018.01.005 · Cited by 20
Demographic Impact of Disasters
Frankenberg, E., Laurito, M. M., & Thomas, D. (2015) · Elsevier eBooks · doi:10.1016/b978-0-08-097086-8.31059-5 · Cited by 20
Evolution of Human Sex-Specific Cognitive Vulnerabilities
Geary, D. C. (2017) · The Quarterly Review of Biology · doi:10.1086/694934 · Cited by 19
Cohort and Period Effects as Explanations for Declining Dementia Trends and Cognitive Aging
Clouston, S., Terrera, G. M., Rodgers, J. L., O’Keefe, P., Mann, F. D., Lewis, N. A., Wänström, L., Kaye, J. A., & Hofer, S. M. (2021) · Population and Development Review · doi:10.1111/padr.12409 · Cited by 21
Do prenatal factors shape the risk for dementia?: A systematic review of the epidemiological evidence for the prenatal origins of dementia
Wiegersma, A. M., Boots, A., Langendam, M. W., Limpens, J., Shenkin, S. D., Kőrösi, A., Roseboom, T. J., & de Rooij, S. R. (2023) · Social Psychiatry and Psychiatric Epidemiology · doi:10.1007/s00127-023-02471-7 · Cited by 19
Self-citation
Babies of the War: The Effect of War Exposure Early in Life on Mortality Throughout Life
Lindeboom, M., & van Ewijk, R. J. G. (2015) · Biodemography and Social Biology · doi:10.1080/19485565.2015.1047489 · Cited by 19
Perinatal protein malnutrition alters expression of miRNA biogenesis genes Xpo5 and Ago2 in mice brain
Berardino, B. G., Fesser, E. A., & Cánepa, E. T. (2017) · Neuroscience Letters · doi:10.1016/j.neulet.2017.03.012 · Cited by 20
The Demography of Disasters
Karácsonyi, D., Taylor, A., & Bird, D. (2020) · Springer eBooks · doi:10.1007/978-3-030-49920-4 · Cited by 19
Association of maternal gestational weight gain with intellectual developmental disorder in the offspring: a nationwide follow‐up study in Sweden
Lee, P., Tse, L. F., László, K., Wei, D., Yu, Y., & Li, J. (2021) · BJOG An International Journal of Obstetrics & Gynaecology · doi:10.1111/1471-0528.16887 · Cited by 19
Size at birth and cognitive ability in late life: A systematic review
Krishna, M., Jones, S., Maden, M., Du, B., Ramya, M. C., Kumaran, K., Karat, S. C., & Fall, C. H. D. (2019) · International Journal of Geriatric Psychiatry · doi:10.1002/gps.5138 · Cited by 19
Out of Africa: Human Capital Consequences of In Utero Conditions
Lavy, V., Schlosser, A., & Shany, A. (2016) · National Bureau of Economic Research · doi:10.3386/w21894 · Cited by 18
Long-Term Outcomes of in Utero Ramadan Exposure: A Systematic Literature Review
Mahanani, M. R., Abderbwih, E., Wendt, A. S., Deckert, A., Antia, K., Horstick, O., Dambach, P., Kohler, S., & Winkler, V. F. (2021) · Nutrients · doi:10.3390/nu13124511 · Cited by 17
Exposure to enriched environment rescues anxiety-like behavior and miRNA deregulated expression induced by perinatal malnutrition while altering oligodendrocyte morphology
Berardino, B. G., Chertoff, M., Gianatiempo, O., Alberca, C. D., Priegue, R., Fiszbein, A., Long, P. T., Corfas, G., & Cánepa, E. T. (2019) · Neuroscience · doi:10.1016/j.neuroscience.2019.03.027 · Cited by 17
Prenatal maternal stress effects on the development of primate social behavior
Schülke, O., Ostner, J., & Berghänel, A. (2019) · Behavioral Ecology and Sociobiology · doi:10.1007/s00265-019-2729-1 · Cited by 17
IVF, from the past to the future: the inheritance of the Capri Workshop Group
The Annual Capri Workshop Group, Albertini, D. F., Crosignani, P., Dumoulin, J. C. M., Evers, J. L. H., Léridon, H., Mastenbroek, S., Painter, R. C., Pinborg, A., Somigliana, E., et al. (2020) · Human Reproduction Open · doi:10.1093/hropen/hoaa040 · Cited by 18
Self-citation
Developmental Conditioning of the Vasculature
Clough, G. F. (2014) · Comprehensive physiology · doi:10.1002/cphy.c140037 · Cited by 22
Long-Run Effects of Gestation During the Dutch Hunger Winter Famine on Labor Market and Hospitalization OutcomesPreprint
Scholte, R. S., van den Berg, G. J., & Lindeboom, M. (2012) · SSRN Electronic Journal · doi:10.2139/ssrn.2005114 · Cited by 17
Consequences of early life exposure to the 1983–1985 Ethiopian Great Famine on cognitive function in adults: a historical cohort study
Arage, G., Belachew, T., Abera, M., Abdulhay, F., Abdulahi, M., & Abate, K. H. (2020) · BMJ Open · doi:10.1136/bmjopen-2020-038977 · Cited by 18
Late-life brain volume: a life-course approach. The AGES-Reykjavik study
Muller, M., Sigurdsson, S. O., Kjartansson, Ó., Gunnarsdóttir, I., Þórsdóttir, I., Harris, T. B., van Buchem, M. A., Gudnason, V. G., & Launer, L. J. (2016) · Neurobiology of Aging · doi:10.1016/j.neurobiolaging.2016.02.012 · Cited by 16
The Importance of the Prenatal Environment in Behavioral Genetics: Introduction to Special Issue
Knopik, V. S., Neiderhiser, J. M., de Geus, E. J. C., & Boomsma, D. I. (2016) · Behavior Genetics · doi:10.1007/s10519-016-9790-6 · Cited by 16
Effects on Transcriptional Regulation and Lipid Droplet Characteristics in the Liver of Female Juvenile Pigs after Early Postnatal Feed Restriction and Refeeding Are Dependent on Birth Weight
Nebendahl, C., Krüger, R., Görs, S., Albrecht, E., Martens, K., Hennig, S., Storm, N., Höppner, W., Pfuhl, R., Metzler-Zebeli, B. U., et al. (2013) · PLoS ONE · doi:10.1371/journal.pone.0076705 · Cited by 16
Collateral Damage: Educational Attainment and Labor Market Outcomes Among German War and Post-War CohortsPreprint
Jürges, H. (2012) · SSRN Electronic Journal · doi:10.2139/ssrn.2014662 · Cited by 16
Hunting for Darwin's gemmules and Lamarck's fluid: Transgenerational signaling and histone methylation
Choi, Y., & Mango, S. E. (2014) · Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms · doi:10.1016/j.bbagrm.2014.05.011 · Cited by 15
Blastocyst-Derived Stem Cell Populations under Stress: Impact of Nutrition and Metabolism on Stem Cell Potency Loss and Miscarriage
Yang, Y., Bolnick, A. D., Shamir, A. M., Abdulhasan, M. A., Li, Q., Parker, G. C., Puscheck, E. E., & Rappolee, D. A. (2017) · Stem Cell Reviews and Reports · doi:10.1007/s12015-017-9734-4 · Cited by 15
Resource Signaling via Blood Glucose in Embodied Decision Making
Wang, X. (2018) · Frontiers in Psychology · doi:10.3389/fpsyg.2018.01965 · Cited by 15
Adult body height as a mediator between early-life conditions and socio-economic status: the case of the Dutch Potato Famine, 1846–1847
Thompson, K., Lindeboom, M., & Portrait, F. R. M. (2019) · Economics & Human Biology · doi:10.1016/j.ehb.2019.04.006 · Cited by 15
Effects of Prenatal Stress on Structural Brain Development and Aging in HumansPreprint
Franke, K., den Bergh, B. R. H. V., de Rooij, S. R., Roseboom, T. J., Nathanielsz, P. W., Witte, O. W., & Schwab, M. G. (2017) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/148916 · Cited by 15
Self-citation
The early life exposome and autism risk: a role for the maternal microbiome?
Gesù, C. M. D., & Buffington, S. A. (2024) · Gut Microbes · doi:10.1080/19490976.2024.2385117 · Cited by 16
No increased risk of psychological/behavioral disorders in siblings of women with hyperemesis gravidarum (HG) unless their mother had HG
Mullin, P., Bray, A., Vu, V., Schoenberg, F. P., MacGibbon, K., Romero, R. J., Goodwin, T. M., & Fejzo, M. S. (2012) · Journal of Developmental Origins of Health and Disease · doi:10.1017/s2040174412000220 · Cited by 14
The enduring effect of prenatal protein malnutrition on brain anatomy, physiology and behavior
Rushmore, J., McGaughy, J. A., Mokler, D. J., & Rosene, D. L. (2020) · Nutritional Neuroscience · doi:10.1080/1028415x.2020.1859730 · Cited by 14
Exposure to the Amino Acids Histidine, Lysine, and Threonine Reduces mTOR Activity and Affects Neurodevelopment in a Human Cerebral Organoid Model
van Berlekom, A. B., Kübler, R., Hoogeboom, J. W., Vonk, D., Sluijs, J. A., Pasterkamp, R. J., Middeldorp, J., Kraneveld, A. D., Garssen, J., Kahn, R. S., et al. (2022) · Nutrients · doi:10.3390/nu14102175 · Cited by 17
The effect of consuming milk and related products during human pregnancy over birth weight and perinatal outcomes: A systematic review and meta-analysis
Pérez‐Roncero, G. R., López-Baena, M. T., Chedraui, P. A., & Pérez-López, F. R. (2020) · European Journal of Obstetrics & Gynecology and Reproductive Biology · doi:10.1016/j.ejogrb.2020.05.061 · Cited by 14
Maternal stress programs a demasculinization of glutamatergic transmission in stress-related brain regions of aged rats
Verhaeghe, R., Gao, V., Morley‐Fletcher, S., Bouwalerh, H., Camp, G. V., Cisani, F., Nicoletti, F., & Maccari, S. (2021) · GeroScience · doi:10.1007/s11357-021-00375-5 · Cited by 14
The political implications of epigenetics
Robison, S. K. (2016) · Politics and the Life Sciences · doi:10.1017/pls.2016.14 · Cited by 14
Sex-specific effects of prenatal undernutrition on resting-state functional connectivity in the human brain at age 68
Boots, A., Thomason, M. E., Espinoza‐Heredia, C., Pruitt, P. J., Damoiseaux, J. S., Roseboom, T. J., & de Rooij, S. R. (2022) · Neurobiology of Aging · doi:10.1016/j.neurobiolaging.2022.01.003 · Cited by 15
Self-citation
Prenatal hypoxia–ischemia decreases spatial memory and increases aggression during adolescence
Indriawati, R., Aswin, S., Susilowati, R., & Partadiredja, G. (2018) · Physiology International · doi:10.1556/2060.105.2018.3.21 · Cited by 13
Programming social behavior by the maternal fragile X protein
Zupan, B., Sharma, A., Frazier, A., Klein, S. L., & Tóth, M. (2016) · Genes Brain & Behavior · doi:10.1111/gbb.12298 · Cited by 14
The effect of birth weight on hospitalizations and sickness absences: a longitudinal study of Swedish siblings
Helgertz, J., & Nilsson, A. (2018) · Journal of Population Economics · doi:10.1007/s00148-018-0706-z · Cited by 12
Diet-Induced Metabolic Dysregulation in Female Mice Causes Osteopenia in Adult Offspring
Shi, Y., Saben, J. L., He, G., Moley, K. H., & Long, F. (2020) · Journal of the Endocrine Society · doi:10.1210/jendso/bvaa028 · Cited by 12
Evolutionary adaptation to juvenile malnutrition impacts adult metabolism and impairs adult fitness in Drosophila
Erkoşar, B., Dupuis, C., Cavigliasso, F., Savary, L., Kremmer, L., Gallart‐Ayala, H., Ivanišević, J., & Kawecki, T. J. (2023) · eLife · doi:10.7554/elife.92465 · Cited by 15
Effect of Fetal and Infant Malnutrition on Metabolism in Older Age
Klimek, P., Leitner, M., Kautzky‐Willer, A., & Stefan Thurner, A. (2014) · Gerontology · doi:10.1159/000358874 · Cited by 12
EARLY LIFE OR EARLY DEATH: SUPPORT FOR CHILD HEALTH LASTS A LIFETIME
Bezruchka, S. (2015) · International Journal of Child Youth and Family Studies · doi:10.18357/ijcyfs.62201513499 · Cited by 13
What doesn’t kill her, will make her depressed
Li, Y., & Sunder, N. (2021) · Economics & Human Biology · doi:10.1016/j.ehb.2021.101064 · Cited by 12
Severe prenatal shocks and adolescent health: Evidence from the Dutch Hunger Winter
Conti, G., Poupakis, S., Ekamper, P., Bijwaard, G. E., & Lumey, L. H. (2024) · Economics & Human Biology · doi:10.1016/j.ehb.2024.101372 · Cited by 12
Birth weight and cognition in children with epilepsy
Jackson, D. C., Lin, J. J., Chambers, K. L., Kessler-Jones, A. M., Jones, J. E., Hsu, D., Stafstrom, C. E., Seidenberg, M., & Hermann, B. P. (2014) · Epilepsia · doi:10.1111/epi.12622 · Cited by 12
Prolonged Febrile Seizures Impair Synaptic Plasticity and Alter Developmental Pattern of Glial Fibrillary Acidic Protein (GFAP)-Immunoreactive Astrocytes in the Hippocampus of Young Rats
Griflyuk, A. V., Postnikova, T. Y., & Zaitsev, A. V. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms232012224 · Cited by 11
Low-nutrient diet in Drosophila larvae stage causes enhancement in dopamine modulation in adult brain due epigenetic imprinting
Zúñiga-Hernández, J. M., Olivares, G. H., Olguı́n, P., & Glavic, Á. (2023) · Open Biology · doi:10.1098/rsob.230049 · Cited by 11
The Hunger Winter: Fighting Famine in the Occupied Netherlands, 1944–1945
de Zwarte, I. J. J. (2020) · Socio-Environmental Systems Modeling · doi:10.1017/9781108872515 · Cited by 10
The long-term effects of superovulation on fertility and sexual behavior of male offspring in mice
Wei, Z.-T., Lu, X., Zhang, G., Yu, J., Li, H., Jia, G.-H., Li, J.-T., & Zhang, J. (2014) · Journal of Assisted Reproduction and Genetics · doi:10.1007/s10815-014-0191-6 · Cited by 10
Postnatal delayed growth impacts cognition but rescues programmed impaired pulmonary vascular development in an IUGR rat model
Yan, L., Wang, Y., Zhang, Z., Xu, S., Ullah, R., Luo, X., Xu, X., Ma, X., Chen, Z., Zhang, L., et al. (2019) · Nutrition Metabolism and Cardiovascular Diseases · doi:10.1016/j.numecd.2019.08.016 · Cited by 10
The neural basis of attentional alterations in prenatally protein malnourished rats
Rushmore, J., McGaughy, J. A., Amaral, A. C. S., Mokler, D. J., Morgane, P. J., Galler, J. R., & Rosene, D. L. (2020) · Cerebral Cortex · doi:10.1093/cercor/bhaa239 · Cited by 10
Ancient Epigenomics
Hanghøj, K., & Orlando, L. (2018) · Population genomics · doi:10.1007/13836_2018_18 · Cited by 10
Association of Parental Famine Exposure With Offspring Depression and Cognition Function
Liu, Y., Liu, Y., Lu, Y., Li, J., & He, S. (2022) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2022.812805 · Cited by 10
Déterminants sociaux des inégalités de santé : une priorité absolue pour la recherche en santé publique
Moatti, J. (2013) · Revue d Épidémiologie et de Santé Publique · doi:10.1016/j.respe.2013.05.012 · Cited by 10
Undernutrition During Fetal Life and the Risk of Cardiovascular Disease in Adulthood
Roseboom, T. J. (2011) · Future Cardiology · doi:10.2217/fca.11.86 · Cited by 10
Self-citation
Instrumental Variable Estimation of the Causal Effect of Hunger Early in Life on Health Later in LifePreprint
van den Berg, G. J., Pinger, P., & Schoch, J. (2012) · SSRN Electronic Journal · doi:10.2139/ssrn.2018771 · Cited by 11
The Effect of Prenatal Exposure to Climate Anomaly on Adulthood Cognitive Function and Job Reputation
Tang, H., & Di, Q. (2022) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph19052523 · Cited by 9
Physiological Slowing and Upregulation of Inhibition in Cortex Are Correlated with Behavioral Deficits in Protein Malnourished Rats
Chaudhary, R., Chugh, M., Darokhan, Z., Katreddi, R. R., Ramachandra, R., & Rema, V. (2013) · PLoS ONE · doi:10.1371/journal.pone.0076556 · Cited by 9
Month of Birth and Dementia Late in Life
Doblhammer, G., & Fritze, T. (2015) · KZfSS Kölner Zeitschrift für Soziologie und Sozialpsychologie · doi:10.1007/s11577-015-0328-3 · Cited by 9
Pigs as Model Species to Investigate Effects of Early Life Events on Later Behavioral and Neurological Functions
Nordquist, R. E., Meijer, E., van der Staay, F. J., & Arndt, S. S. (2017) · Elsevier eBooks · doi:10.1016/b978-0-12-809468-6.00039-5 · Cited by 11
Caloric restriction can affect one-carbon metabolism during pregnancy in the rat: A transgenerational model
Chmurzyńska, A., Młodzik-Czyżewska, M. A., Radziejewska, A., Szwengiel, A., Malinowska, A. M., & Nowacka‐Woszuk, J. (2018) · Biochimie · doi:10.1016/j.biochi.2018.07.007 · Cited by 9
Prenatal Protein Malnutrition Produces Resistance to Distraction Similar to Noradrenergic Deafferentation of the Prelimbic Cortex in a Sustained Attention Task
Newman, L. A., Baraiolo, J., Mokler, D. J., Rabinowitz, A. G., Galler, J. R., & McGaughy, J. A. (2019) · Frontiers in Neuroscience · doi:10.3389/fnins.2019.00123 · Cited by 10
Association between early-life famine exposure and cognitive function trajectories from midlife to late-life: The mediating role of depressive symptoms
He, H., Li, F., Zhu, Z., Liao, Y., Li, H., Zou, Y., & Peng, Y. (2025) · Clinical Nutrition · doi:10.1016/j.clnu.2025.04.026 · Cited by 8
Developmental Effects of Endocrine-Disrupting Chemicals in the Ovary and on Female Fertility
Uzumcu, M., & Zama, A. (2016) · Elsevier eBooks · doi:10.1016/b978-0-12-801383-0.00009-8 · Cited by 5

Authors: de Rooij, S. R., Wouters, H., Yonker, J. E., Painter, R. C., & Roseboom, T. J.
Affiliations: Departments of aClinical Epidemiology Biostatistics and Bioinformatics, and
Calvin University (US)
Amsterdam UMC Location University of Amsterdam (NL)
University of Missouri (US)
ORCID: Wouters, Hans
Yonker, Julie E.
Painter, Rebecca C.
Roseboom, Tessa J.
Venue: Proceedings of the National Academy of Sciences
Publisher: National Academy of Sciences
Published: 2010-09-13
Volume: 107
Issue: 39
Pages: 16881-16886
ISSN: 0027-8424 (ISSN-L)
1091-6490
DOI: 10.1073/pnas.1009459107
PMC: PMC2947913
OpenAlex: W2010036492
Cited by: 364
References: 38
Citations by year: 2026: 5 · 2025: 13 · 2024: 16 · 2023: 18 · 2022: 27 · 2021: 29 · 2020: 42 · 2019: 32 · 2018: 18 · 2017: 22 · 2016: 21 · 2015: 26 · 2014: 24 · 2013: 32 · 2012: 24
FWCI: 20.70
Type: journal article
Language: en
Open access: green
www.ncbi.nlm.nih.gov
Locations: Proceedings of the National Academy of Sciences (publishedVersion)
PubMed Central (publishedVersion)
PubMed (publishedVersion)
Pure Amsterdam UMC (publishedVersion)
Data Archiving and Networked Services (DANS) (submittedVersion)
University of Groningen research database (University of Groningen / Centre for Information Technology) (submittedVersion)
Funders: European Science Foundation
Medical Research Council
Topics: Health Sciences › Medicine › Pediatrics, Perinatology and Child Health › Birth, Development, and Health
Social Sciences › Psychology › Experimental and Cognitive Psychology › Cognitive Abilities and Testing
Health Sciences › Medicine › Psychiatry and Mental health › Dementia and Cognitive Impairment Research
Keywords: prenatal malnutrition, Dutch famine, cognitive aging, old age, selective attention, cognitive decline, prenatal exposure
MeSH terms: Adult, Attention, Cognition, Cognition Disorders, Female, Humans, Male, Netherlands, Pregnancy, Starvation, Maternal Exposure, Prenatal Nutritional Physiological Phenomena, Malnutrition

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

Prenatal undernutrition and cognitive function in late adulthood

Abstract

Overview

Integrity signals

Verification

Claims the paper makes

Claims other papers make about this one

Self-check

Citations

Cites

Cited by

Related

Metadata

Record

About these checks