The DOI matches its Crossref record; 39 of the 39 references it cites were found in a registry or an index.
Prenatal undernutrition and cognitive function in late adulthood
Open accessAbstract
At the end of World War II, a severe 5-mo famine struck the cities in the western part of The Netherlands. At its peak, the rations dropped to as low as 400 calories per day. In 1972, cognitive performance in 19-y-old male conscripts was reported not to have been affected by exposure to the famine before birth. In the present study, we show that cognitive function in later life does seem affected by prenatal undernutrition. We found that at age 56 to 59, men and women exposed to famine during the early stage of gestation performed worse on a selective attention task, a cognitive ability that usually declines with increasing age. We hypothesize that this decline may be an early manifestation of an accelerated cognitive aging process.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
In the citing paper
“In addition, the pancreas has fewer insulin-producing beta cells and reduced vascularization (159, 340, 473), and the structure and maturation of the brain (142), lungs (358, 359, 424, 460) and liver (209, 474) are compromised.”
From Placental Origins of Chronic Disease (2016) · cites this paper as [142]
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
The Hospital Anxiety and Depression Scale
Zigmond, A. S., & Snaith, R. P. (1983) · Acta Psychiatrica Scandinavica · doi:10.1111/j.1600-0447.1983.tb09716.x · Cited by 47,139
Studies of interference in serial verbal reactions
Stroop, J. R. (1935) · Journal of Experimental Psychology · doi:10.1037/h0054651 · Cited by 18,622
Half a century of research on the Stroop effect: An integrative review.
MacLeod, C. M. (1991) · Psychological Bulletin · doi:10.1037/0033-2909.109.2.163 · Cited by 5,500
Extending Healthy Life Span—From Yeast to Humans
Fontana, L., Partridge, L., & Longo, V. D. (2010) · Science · doi:10.1126/science.1172539 · Cited by 3,023
Glucose tolerance in adults after prenatal exposure to famine
Ravelli, A., van der Meulen, J., Michels, R., Osmond, C., Barker, D., Hales, C., & Bleker, O. (1998) · The Lancet · doi:10.1016/s0140-6736(97)07244-9 · Cited by 1,606
Obesity at the age of 50 y in men and women exposed to famine prenatally
Ravelli, A. C. J., van der Meulen, J., Osmond, C., Barker, D. J. P., & Bleker, O. P. (1999) · American Journal of Clinical Nutrition · doi:10.1093/ajcn/70.5.811 · Cited by 1,165
The Dutch Famine and Its Long-Term Consequences for Adult Health
Roseboom, T., de Rooij, S., & Painter, R. (2006) · Early Human Development · doi:10.1016/j.earlhumdev.2006.07.001 · Cited by 1,137
Self-citationBreteler, M. M. B., Swieten, J. C. V., Bots, M. L., Grobbee, D. E., Claus, J. J., Hout, J. H. W. V. D., van Harskamp, F., Tanghe, H. L. J., de Jong, P. T. V. M., van Gijn, J., et al. (1994) · Neurology · doi:10.1212/wnl.44.7.1246 · Cited by 1,006
Hibbeln, J. R., Davis, J. M., Steer, C., Emmett, P., Rogers, I., Williams, C., & Golding, J. (2007) · The Lancet · doi:10.1016/s0140-6736(07)60277-3 · Cited by 987
Alzheimer Disease as a Vascular Disorder
de la Torre, J. C. (2002) · Stroke · doi:10.1161/01.str.0000014421.15948.67 · Cited by 852
Research works printed but not linked: 4
- ; National Bureau of Food Distribution in Wartime Rations per day period 1 Oct 1944– 22 July 1945 for the western Netherlands, (Translated from the Dutch). (1945).
- GCE Burger, HR Sandstead, JC Drummond Malnutrition and Starvation in Western Netherlands, September 1944 to July 1945. Part I and II (General State Printing Office, The Hague, 1948).
- B Bakker, I Sieben, International Socio-Economic Index of occupational status (1992). Soc Wetenschappen 40, 1–22, (Translated from the Dutch). (1997).
- A Heim AH4 Group Test of General Intelligence (NFER-Nelson Publishing Company Ltd, Windsor, United Kingdom, 1970).
Cited by
Sorted by citations
Items 301–361 of 361
Human Vulnerability for Brain and Cognitive Traits
Geary, D. C. (2015) · Elsevier eBooks · doi:10.1016/b978-0-12-801562-9.00007-7
Çamsarı, Ç. (2015) · Michigan State University Libraries · doi:10.25335/hxap-mr94
DNA methylation changes in allergic airway disease
Eyring, K. R. (2015) · doi:10.25677/pdc3-g562
Economic conditions at the time of birth and cognitive abilities late in life
Doblhammer, G., van den Berg, G. J., & Fritze, T. (2013) · PLoS ONE
Prenatal maternal stress and child ADHD symptoms in early childhood
Huhtala, E. (2015) · Työväentutkimus Vuosikirja
Perinatal self-care could alter outcomes for children
Williams, E. (2017) · Journal of Health Visiting · doi:10.12968/johv.2017.5.8.414
Prenatal Undernutrition and Ageing and Longevity
de Rooij, S. R. (2019) · Healthy ageing and longevity · doi:10.1007/978-3-030-24958-8_10
Immunological Basis of In Utero Programming of Adult Disease
Golden, T., & Simmons, R. A. (2019) · Healthy ageing and longevity · doi:10.1007/978-3-030-24958-8_4
Nutrition in Neurocognition and Mental Health
Katrinak, M., Irani, F., Armstrong, C. L., & Kerr, S. (2019) · Springer eBooks · doi:10.1007/978-3-030-14895-9_28
SOMATO-SEXUAL DEVELOPMENT OF DESCENDANTS BORN FROM MOTHERS WITH FETOPLACENTARY INSUFFICIENCY
Seliukova, N. Y., Misyura, K. V., Стороженко, Г. В., & Волохов, І. В. (2020) · Bulletin of Problems Biology and Medicine · doi:10.29254/2077-4214-2020-3-157-142-145
Seliukova, N. (2020) · Ukraïnsʹkij žurnal medicini bìologìï ta sportu · doi:10.26693/jmbs05.06.362
Seliukova, N. Y. (2021) · Scientific Bulletin of Natural Sciences (Biological Sciences) · doi:10.32999/ksu2524-0838/2020-29-6
Comparação de redes de regulação gênica da placenta em resposta à exposição ao estresse entre sexos
Barbosa, A. D. L. (2020) · Digital Library of Theses and Dissertations (Universidade de São Paulo) · doi:10.11606/t.95.2020.tde-09122020-200928
The Politics and Practices of Allied Relief
de Zwarte, I. J. J. (2020) · Cambridge University Press eBooks · doi:10.1017/9781108872515.007
de Zwarte, I. J. J. (2020) · Cambridge University Press eBooks · doi:10.1017/9781108872515.010
de Zwarte, I. J. J. (2020) · Cambridge University Press eBooks · doi:10.1017/9781108872515.004
de Zwarte, I. J. J. (2020) · Cambridge University Press eBooks · doi:10.1017/9781108872515.011
de Zwarte, I. J. J. (2020) · Cambridge University Press eBooks · doi:10.1017/9781108872515.009
de Zwarte, I. J. J. (2020) · Cambridge University Press eBooks · doi:10.1017/9781108872515.013
de Zwarte, I. J. J. (2020) · Cambridge University Press eBooks · doi:10.1017/9781108872515.002
de Zwarte, I. J. J. (2020) · Cambridge University Press eBooks · doi:10.1017/9781108872515.003
Central Government and Food Administration
de Zwarte, I. J. J. (2020) · Cambridge University Press eBooks · doi:10.1017/9781108872515.006
Appendix: Timeline of Important Events
de Zwarte, I. J. J. (2020) · doi:10.1017/9781108872515.012
Effects on Mortality, Fertility, and Health in Later Life
de Zwarte, I. J. J. (2020) · Cambridge University Press eBooks · doi:10.1017/9781108872515.005
Coping at Household and Individual Levels
de Zwarte, I. J. J. (2020) · Cambridge University Press eBooks · doi:10.1017/9781108872515.008
On the Empirical Study of Atrocity Crimes
Bijleveld, C. C. J. H. (2022) · Oxford University Press eBooks · doi:10.1093/oxfordhb/9780190915629.013.2
de Zwarte, I. J. J. (2020) · doi:10.1017/9781108872515.001
(2016) · Elsevier eBooks · doi:10.1016/b978-0-12-804538-1.00036-5
The Effects of Prenatal Exposure to the Dutch Famine 1944–1945 on Health Across the Lifecourse
Roseboom, T. J. (2017) · Springer eBooks · doi:10.1007/978-3-319-40007-5_24-1
Self-citationde Zwarte, I. J. J. (2020) · Cambridge University Press eBooks · doi:10.1017/9781108872515.014
(2015) · Elsevier eBooks · doi:10.1016/b978-0-12-801562-9.09998-1
Sadler, M., Said, K., Chuma, E., Kaminyoge, S. M., Mussa, B., Kuhoga, E., Walker, R. W., Livingston, G., Gray, W. K., Paddick, S., et al. (2022) · Research Square · doi:10.21203/rs.3.rs-1941126/v1
Holla, A. (2023) · World Bank, Washington, DC eBooks · doi:10.1596/978-1-4648-1901-8_ch2
He, H., Xu, M., Li, F. R., Zhao, Y., Wang, J., & Ma, J. (2023) · Springer eBooks · doi:10.1007/978-981-19-9538-5_8
Kim, B., Efird, J. T., & Hu, J. (2023) · Diabetology · doi:10.3390/diabetology4030028
Tomihara, K. (2023) · Japanese Journal of Animal Psychology · doi:10.2502/janip.73.2.7
Boots, A., Schrantee, A., Wiegersma, A. M., Aflalo, S., Groot, P. F. C., Roseboom, T. J., & de Rooij, S. R. (2024) · Brain and Cognition · doi:10.1016/j.bandc.2024.106162
Self-citationWiegersma, A. M., Boots, A., van Bussel, E. F., Lissenberg-Witte, B. I., Nielen, M. M. J., Roseboom, T. J., & de Rooij, S. R. (2024) · Current Alzheimer Research · doi:10.2174/0115672050290699240422050036
Self-citationAdult Physical Function Has Roots in Early Childhood Brain Function: A Five-Decade Cohort Study
Xie, J., Caspi, A., Harrington, H., Houts, R., Pietrosimone, B., Whitman, E. T., McKinney, L. W., & Moffitt, T. E. (2024) · The Journals of Gerontology Series B · doi:10.1093/geronb/gbae119
A Life-Span Perspective on the Effects of Early-Life Adversity on Cognitive Aging
Manavbasi, I. E., & Stine‐Morrow, E. A. L. (2024) · Oxford University Press eBooks · doi:10.1093/oxfordhb/9780197677131.013.25
Vasile, A., Martiniuc, C., SC AUTEUR SRL, B., Dăscălescu, G., Ciobica, A. S., & Mavroudis, I. A. (2024) · Annals of the Academy of Romanian Scientists Series on Biological Sciences · doi:10.56082/annalsarscibio.2024.2.91
Slopen, N. B., & Shonkoff, J. P. (2025) · doi:10.1093/oso/9780198895961.003.0017
Kumari, A. (2025) · Springer transactions in civil and environmental engineering · doi:10.1007/978-981-96-4047-8_2
Longitudinal changes in late-life brain health after prenatal exposure to the Dutch famine
Boots, A., Schrantee, A., Padrela, B. E., Wiegersma, A. M., Damoiseaux, J. S., Mutsaerts, H. J. M. M., Lorenzini, L., Roseboom, T. J., & de Rooij, S. R. (2025) · NeuroImage · doi:10.1016/j.neuroimage.2025.121505
Self-citationMaternal Nutrition for Healthy Pregnancy, Including the Conception, Antenatal, and Postnatal Periods
Agroia, H. K. (2025) · Nutrition and health · doi:10.1007/978-3-031-95373-6_11
Origen neonatal de la síndrome metabòlica en l'adult
Pentinat, T. (2013) · LA Referencia (Red Federada de Repositorios Institucionales de Publicaciones Científicas)
Abate, K. H., Abdullahi, M., Abdulhay, F., Arage, G., Mecha, M., Yenuss, M., Hassen, H., & Belachew, T. (2021) · Figshare · doi:10.6084/m9.figshare.14538758
Wiegersma, A. M., Boots, A., Roseboom, T. J., & de Rooij, S. R. (2022) · Figshare · doi:10.6084/m9.figshare.19298381
Self-citationAbate, K. H., Abdullahi, M., Abdulhay, F., Arage, G., Mecha, M., Yenuss, M., Hassen, H., & Belachew, T. (2021) · Figshare · doi:10.6084/m9.figshare.14538755
Using facial cues to produce social decisions. A cognitive and evolutionary approach
Safra, L. (2017) · theses.fr (ABES) · doi:10.70675/47319474zdbe9z43fdzaf6ezc6d9d29319c0 · Cited by 1
Lemaire, M. (2018) · theses.fr (ABES) · doi:10.70675/d4a3481fzc7f5z40b0zba41z08905cdd9ce8 · Cited by 1
1178 Siege Warfare: Epidemiological and Humanitarian Aspects
Pintor, M. P. (2025) · De Gruyter eBooks · doi:10.1515/9783111250144-009
Vasiljevic, E., Schmitz, L., & Maenner, M. J. (2026) · medRxiv · doi:10.64898/2026.06.11.26355481
The consequences of food and flight efficiency for the timing of natal dispersal in golden eagles
Hatzl, J. S., Tschumi, M., Bassi, E., Cruickshank, S. S., Jenny, D., Pellissier, L., Safi, K., Scharf, A. K., Sumasgutner, P., & Grüebler, M. U. (2026) · Animal Behaviour · doi:10.1016/j.anbehav.2026.123712
Childbirth Effects of the 2004 Indian Ocean Tsunami
Hur, E. K., & Lee, S.-H. (2026) · Oxford Bulletin of Economics and Statistics · doi:10.1111/obes.70141
Pre- and Perinatal Influences on Female Mental Health
Axness, M., & Evans, J. (2014) · Springer eBooks · doi:10.1007/978-3-319-05116-1_1
Mparmpakas, D. (2011) · Brunel University Research Archive (BURA) (Brunel University London)
Metadata
- Authors
- de Rooij, S. R., Wouters, H., Yonker, J. E., Painter, R. C., & Roseboom, T. J.
- Affiliations
- Departments of aClinical Epidemiology Biostatistics and Bioinformatics, and
- Calvin University (US)
- Amsterdam UMC Location University of Amsterdam (NL)
- University of Missouri (US)
- Venue
- Proceedings of the National Academy of Sciences
- Publisher
- National Academy of Sciences
- Published
- 2010-09-13
- Volume
- 107
- Issue
- 39
- Pages
- 16881-16886
- ISSN
- 0027-8424 (ISSN-L)
- 1091-6490
- PMC
- PMC2947913
- OpenAlex
- W2010036492
- Cited by
- 364
- References
- 38
- Citations by year
- 2026: 5 · 2025: 13 · 2024: 16 · 2023: 18 · 2022: 27 · 2021: 29 · 2020: 42 · 2019: 32 · 2018: 18 · 2017: 22 · 2016: 21 · 2015: 26 · 2014: 24 · 2013: 32 · 2012: 24
- FWCI
- 20.70
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- Proceedings of the National Academy of Sciences (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- Pure Amsterdam UMC (publishedVersion)
- Data Archiving and Networked Services (DANS) (submittedVersion)
- University of Groningen research database (University of Groningen / Centre for Information Technology) (submittedVersion)
- Funders
- European Science Foundation
- Medical Research Council
- Topics
- Health Sciences › Medicine › Pediatrics, Perinatology and Child Health › Birth, Development, and Health
- Social Sciences › Psychology › Experimental and Cognitive Psychology › Cognitive Abilities and Testing
- Health Sciences › Medicine › Psychiatry and Mental health › Dementia and Cognitive Impairment Research
- Keywords
- prenatal malnutrition, Dutch famine, cognitive aging, old age, selective attention, cognitive decline, prenatal exposure
- MeSH terms
- Adult, Attention, Cognition, Cognition Disorders, Female, Humans, Male, Netherlands, Pregnancy, Starvation, Maternal Exposure, Prenatal Nutritional Physiological Phenomena, Malnutrition
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
