Niche of harmful alga Aureococcus anophagefferens revealed through ecogenomics
Open accessAbstract
Harmful algal blooms (HABs) cause significant economic and ecological damage worldwide. Despite considerable efforts, a comprehensive understanding of the factors that promote these blooms has been lacking, because the biochemical pathways that facilitate their dominance relative to other phytoplankton within specific environments have not been identified. Here, biogeochemical measurements showed that the harmful alga Aureococcus anophagefferens outcompeted co-occurring phytoplankton in estuaries with elevated levels of dissolved organic matter and turbidity and low levels of dissolved inorganic nitrogen. We subsequently sequenced the genome of A. anophagefferens and compared its gene complement with those of six competing phytoplankton species identified through metaproteomics. Using an ecogenomic approach, we specifically focused on gene sets that may facilitate dominance within the environmental conditions present during blooms. A. anophagefferens possesses a larger genome (56 Mbp) and has more genes involved in light harvesting, organic carbon and nitrogen use, and encoding selenium- and metal-requiring enzymes than competing phytoplankton. Genes for the synthesis of microbial deterrents likely permit the proliferation of this species, with reduced mortality losses during blooms. Collectively, these findings suggest that anthropogenic activities resulting in elevated levels of turbidity, organic matter, and metals have opened a niche within coastal ecosystems that ideally suits the unique genetic capacity of A. anophagefferens and thus, has facilitated the proliferation of this and potentially other HABs.
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
Selenium is an essential metal in metazoans and some algae for the production of Se-requiring glutathione peroxidase, used to metabolize hydrogen peroxide and lipid hydroperoxides.
“Selenium is an essential metal in metazoans and some algae for the production of Se-requiring glutathione peroxidase, used to metabolize hydrogen peroxide and lipid hydroperoxides (Halliwell and Gutteridge 2007; Perez et al. 2007; Gobler et al. 2011).”
From Algae as nutritional and functional food sources: revisiting our understanding. (2017) · cites this paper as Gobler et al. 2011
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Cites
Basic local alignment search tool
Altschul, S. F., Gish, W., Miller, W., Myers, E. W., & Lipman, D. J. (1990) · Journal of Molecular Biology · doi:10.1006/jmbi.1990.9999 · Cited by 98,669 · see citing works
Gene Ontology: tool for the unification of biology
Ashburner, M., Ball, C. A., Blake, J. A., Botstein, D., Butler, H., Cherry, J. M., Davis, A. P., Dolinski, K., Dwight, S. S., Eppig, J. T., et al. (2000) · Nature Genetics · doi:10.1038/75556 · Cited by 43,206 · see citing works
Hall, T. A. (1999) · Nucleic Acids Symposium Series · doi:10.14601/phytopathol_mediterr-14998u1.29 · Cited by 38,373 · see citing works
MEGA4: Molecular Evolutionary Genetics Analysis (MEGA) Software Version 4.0
Tamura, K., Dudley, J. T., Nei, M., & Kumar, S. (2007) · Molecular Biology and Evolution · doi:10.1093/molbev/msm092 · Cited by 28,734 · see citing works
The Pfam Protein Families Database
Bateman, A. G. (2002) · Nucleic Acids Research · doi:10.1093/nar/30.1.276 · Cited by 14,062 · see citing works
Eng, J. K., McCormack, A. L., & Yates, J. R. (1994) · Journal of the American Society for Mass Spectrometry · doi:10.1016/1044-0305(94)80016-2 · Cited by 6,484 · see citing works
A Manual of Chemical and Biological Methods for Seawater Analysis.
PARSONS, T. R., Maita, Y., & LALLI, C. M. (1984) · doi:10.25607/obp-1830 · Cited by 5,744 · see citing works
The KEGG resource for deciphering the genome
Kanehisa, M. (2003) · Nucleic Acids Research · doi:10.1093/nar/gkh063 · Cited by 5,121 · see citing works
The COG database: a tool for genome-scale analysis of protein functions and evolution
Tatusov, R. L. (2000) · Nucleic Acids Research · doi:10.1093/nar/28.1.33 · Cited by 4,480 · see citing works
The SWISS-PROT protein knowledgebase and its supplement TrEMBL in 2003
Boeckmann, B. (2003) · Nucleic Acids Research · doi:10.1093/nar/gkg095 · Cited by 3,894 · see citing works
A genomic perspective on protein families.
Tatusov, R., Koonin, E., & Lipman, D. (1997) · Science · doi:10.1126/science.278.5338.631 · Cited by 3,777 · see citing works
Depletion, degradation, and recovery potential of estuaries and coastal seas
Lotze, H. K., Lenihan, H. S., Bourque, B. J., Bradbury, R. H., Cooke, R. G., Kay, M. C., Kidwell, S. M., Kirby, M. X., Peterson, C. H., & Jackson, J. B. C. (2006) · Science · doi:10.1126/science.1128035 · Cited by 3,402 · see citing works
InterProScan – an integration platform for the signature-recognition methods in InterPro
Zdobnov, E. M., & Apweiler, R. (2001) · Bioinformatics · doi:10.1093/bioinformatics/17.9.847 · Cited by 2,915 · see citing works
The Pfam protein families database
Finn, R. D., Mistry, J., Tate, J., Coggill, P., Heger, A., Pollington, J. E., Gavin, O. L., Gunasekaran, P., Ceric, G., Forslund, K., et al. (2010) · Nucleic Acids Research · doi:10.1093/nar/gkp985 · Cited by 2,694 · see citing works
Eutrophication and harmful algal blooms: a scientific consensus
Heisler, J., Glibert, P. M., Burkholder, J. M., Anderson, D. M., Cochlan, W., Dennison, W. C., Dortch, Q., Gobler, C. J., Heil, C. A., Humphries, E., et al. (2008) · Harmful Algae · doi:10.1016/j.hal.2008.08.006 · Cited by 2,090 · see citing works
Self-citationThe Genome of the Diatom Thalassiosira Pseudonana : Ecology, Evolution, and Metabolism
Armbrust, E. V., Berges, J. A., Bowler, C., Green, B. R., Martínez, D., Putnam, N. H., Zhou, S., Allen, A. E., Apt, K. E., Bechner, M., et al. (2004) · Science · doi:10.1126/science.1101156 · Cited by 2,029 · see citing works
Self-citationThe Phaeodactylum genome reveals the evolutionary history of diatom genomes
Bowler, C., Allen, A. E., Badger, J., Grimwood, J., Jabbari, K., Kuo, A., Maheswari, U., Martens, C., Maumus, F., Otillar, R., et al. (2008) · Nature · doi:10.1038/nature07410 · Cited by 1,656 · see citing works
Self-citationWhole-Genome Shotgun Assembly and Analysis of the Genome of <i>Fugu rubripes</i>
Aparicio, S., Chapman, J., Stupka, E., Putnam, N., Chia, J.-M., Dehal, P., Christoffels, A., Rash, S., Hoon, S., Smit, A., et al. (2002) · Science · doi:10.1126/science.1072104 · Cited by 1,591 · see citing works
Self-citationThe ancient regulatory-protein family of WD-repeat proteins
Neer, E. J., Schmidt, C. J., Nambudripad, R., & Smith, T. F. (1994) · Nature · doi:10.1038/371297a0 · Cited by 1,491 · see citing works
The simultaneous analysis of total nitrogen and total phosphorus in natural waters
Valderrama, J. (1981) · Marine Chemistry · doi:10.1016/0304-4203(81)90027-x · Cited by 1,455 · see citing works
Tabb, D. L., McDonald, W. H., & Yates, J. R. (2002) · Journal of Proteome Research · doi:10.1021/pr015504q · Cited by 1,369 · see citing works
Harmful algal blooms: Their ecophysiology and general relevance to phytoplankton blooms in the sea
Smayda, T. J. (1997) · Limnology and Oceanography · doi:10.4319/lo.1997.42.5_part_2.1137 · Cited by 1,286 · see citing works
Polyphenol oxidases in plants and fungi: Going places? A review
Mayer, A. M. (2006) · Phytochemistry · doi:10.1016/j.phytochem.2006.08.006 · Cited by 1,177 · see citing works
Ab initio Gene Finding in Drosophila Genomic DNAPreprint
Salamov, A. A., & Solovyev, V. V. (2000) · Genome Research · doi:10.1101/gr.10.4.516 · Cited by 1,112 · see citing works
Self-citationA comprehensive evolutionary classification of proteins encoded in complete eukaryotic genomes
Koonin, E. V., Fedorova, N. D., Jackson, J. D., Jacobs, A. R., Krylov, D. M., Makarova, K. S., Mazumder, R., Mekhedov, S., Nikolskaya, A. N., Rao, B. S., et al. (2004) · Genome biology · doi:10.1186/gb-2004-5-2-r7 · Cited by 1,092 · see citing works
ABC Multidrug Transporters: Structure, Function and Role in Chemoresistance
Sharom, F. J. (2007) · Pharmacogenomics · doi:10.2217/14622416.9.1.105 · Cited by 973 · see citing works
The Ectocarpus genome and the independent evolution of multicellularity in brown algae
Cock, J., Sterck, L., Rouzé, P., Scornet, D., Allen, A., Amoutzias, G., Anthouard, V., Artiguenave, F., Aury, J., Badger, J. H., et al. (2010) · Nature · doi:10.1038/nature09016 · Cited by 933 · see citing works
Stadtman, T. C. (1996) · Annual Review of Biochemistry · doi:10.1146/annurev.bi.65.070196.000503 · Cited by 827 · see citing works
THE CHLOROPHYLL-CAROTENOID PROTEINS OF OXYGENIC PHOTOSYNTHESIS
Green, B. R., & Durnford, D. G. (1996) · Annual Review of Plant Physiology and Plant Molecular Biology · doi:10.1146/annurev.arplant.47.1.685 · Cited by 749 · see citing works
How Selenium Has Altered Our Understanding of the Genetic Code
Hatfield, D. L., & Gladyshev, V. N. (2002) · Molecular and Cellular Biology · doi:10.1128/mcb.22.11.3565-3576.2002 · Cited by 681 · see citing works
Self-citationAnderson, D. M., Burkholder, J. M., Cochlan, W. P., Glibert, P. M., Gobler, C. J., Heil, C. A., Kudela, R. M., Parsons, M. L., Rensel, J. E., Townsend, D. W., et al. (2008) · Harmful Algae · doi:10.1016/j.hal.2008.08.017 · Cited by 671 · see citing works
Self-citationCommunity Proteomics of a Natural Microbial Biofilm
Ram, R. J., VerBerkmoes, N. C., Thelen, M. P., Tyson, G. W., Baker, B. J., Blake, R. C., Shah, M. B., Hettich, R. L., & Banfield, J. F. (2005) · Science · doi:10.1126/science.1109070 · Cited by 659 · see citing works
Self-citationPalenik, B., Grimwood, J., Aerts, A., Rouzé, P., Salamov, A., Putnam, N., Dupont, C., Jorgensen, R., Derelle, E., Rombauts, S., et al. (2007) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0611046104 · Cited by 625 · see citing works
Self-citationFacchini, P. J. (2001) · Annual Review of Plant Physiology and Plant Molecular Biology · doi:10.1146/annurev.arplant.52.1.29 · Cited by 623 · see citing works
The Nucleobase‐Cation‐Symport‐1 Family of Membrane Transport Proteins
Weyand, S. N., Ma, P., Saidijam, M., Baldwin, J. M., Beckstein, O., Jackson, S. M., Suzuki, S., Patching, S. G., Shimamura, T., Sansom, M. S. P., et al. (2004) · Handbook of Metalloproteins · doi:10.1002/0470028637.met268 · Cited by 619 · see citing works
The evolutionary inheritance of elemental stoichiometry in marine phytoplankton
Quigg, A. S., Finkel, Z. V., Irwin, A. J., Rosenthal, Y., Ho, T., Reinfelder, J. R., Schofield, O., Morel, F. M. M., & Falkowski, P. G. (2003) · Nature · doi:10.1038/nature01953 · Cited by 538 · see citing works
Paerl, H., Pinckney, J. L., Fear, J. M., & Peierls, B. L. (1998) · Marine Ecology Progress Series · doi:10.3354/meps166017 · Cited by 537 · see citing works
Granéli, E., & Turner, J. T. (2006) · Ecological studies · doi:10.1007/978-3-540-32210-8 · Cited by 515 · see citing works
Schmeller, T., Latz-Brüning, B., & Wink, M. (1997) · Phytochemistry · doi:10.1016/s0031-9422(96)00545-6 · Cited by 413 · see citing works
Using GeneWise in the Drosophila Annotation ExperimentPreprint
Birney, E., & Durbin, R. M. (2000) · Genome Research · doi:10.1101/gr.10.4.547 · Cited by 396 · see citing works
Ren, Q., Chen, K., & Paulsen, I. T. (2006) · Nucleic Acids Research · doi:10.1093/nar/gkl925 · Cited by 373 · see citing works
Self-citationA Common Fold Mediates Vertebrate Defense and Bacterial Attack
Rosado, C. J., Buckle, A. M., Law, R. H. P., Butcher, R. E., Kan, W., Bird, C. H., Ung, K. S., Browne, K. A., Baran, K., Bashtannyk-Puhalovich, T. A., et al. (2007) · Science · doi:10.1126/science.1144706 · Cited by 278 · see citing works
Genome sequence of Synechococcus CC9311: Insights into adaptation to a coastal environment
Palenik, B. P., Ren, Q., Dupont, C. L., Myers, G. S. A., Heidelberg, J. F., Badger, J. H., Madupu, R., Nelson, W. C., Brinkac, L. M., Dodson, R. J., et al. (2006) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0602963103 · Cited by 266 · see citing works
Self-citationSunda, W. G., Graneli, E., & Gobler, C. J. (2006) · Journal of Phycology · doi:10.1111/j.1529-8817.2006.00261.x · Cited by 265 · see citing works
Self-citationBordo, D., Pesce, A., Bolognesi, M., Stroppolo, M., FALCONI, M., & DESIDERI, A. (2006) · Wiley eBooks · doi:10.1002/0470028637 · Cited by 264 · see citing works
TRACE ELEMENT CONTENT OF SELECTED FERTILIZERS AND DAIRY MANURES AS DETERMINED BY ICP–MS
McBride, M. B., & Spiers, G. (2001) · Communications in Soil Science and Plant Analysis · doi:10.1081/css-100102999 · Cited by 263 · see citing works
The Economic Effects of Harmful Algal Blooms
Hoagland, P., & Scatasta, S. (2006) · Springer eBooks · doi:10.1007/978-3-540-32210-8_30 · Cited by 258 · see citing works
LaRoche, J., Nuzzi, R., WATERS, R., Wyman, K. D., Falkowski, P. G., & Wallace, D. W. R. (1997) · Global Change Biology · doi:10.1046/j.1365-2486.1997.00117.x · Cited by 241 · see citing works
Durnford, D. G., Deane, J. A., Tan, S. Y., McFadden, G. I., Gantt, E., & Green, B. R. (1999) · Journal of Molecular Evolution · doi:10.1007/pl00006445 · Cited by 235 · see citing works
Lobanov, A. V., Fomenko, D. E., Zhang, Y., Sengupta, A., Hatfield, D. L., & Gladyshev, V. N. (2007) · Genome biology · doi:10.1186/gb-2007-8-9-r198 · Cited by 204 · see citing works
Self-citationMolecular Dynamics of the Shewanella oneidensis Response to Chromate Stress
Brown, S. D., Thompson, M. R., VerBerkmoes, N. C., Chourey, K., Shah, M. B., Zhou, J. Z., Hettich, R. L., & Thompson, D. K. (2006) · Molecular & Cellular Proteomics · doi:10.1074/mcp.m500394-mcp200 · Cited by 195 · see citing works
Self-citationGenome streamlining and the elemental costs of growth
Hessen, D. O., Jeyasingh, P. D., Neiman, M., et al. (2009) · Trends in Ecology & Evolution · doi:10.1016/j.tree.2009.08.004 · Cited by 183 · see citing works
Kim, H., & Gladyshev, V. N. (2005) · PLoS Biology · doi:10.1371/journal.pbio.0030375 · Cited by 182 · see citing works
Self-citationGobler, C. J., Lonsdale, D. J., & Boyer, G. L. (2005) · Estuaries · doi:10.1007/bf02732911 · Cited by 176 · see citing works
Self-citationSel1-like repeat proteins in signal transduction
Mittl, P. R. E., & Schneider‐Brachert, W. (2006) · Cellular Signalling · doi:10.1016/j.cellsig.2006.05.034 · Cited by 164 · see citing works
Particle Analysis in Oceanography
(1991) · Springer eBooks · doi:10.1007/978-3-642-75121-9 · Cited by 163 · see citing works
The ABC family of multidrug transporters in microorganisms
van Veen, H. W., & Konings, W. N. (1998) · Biochimica et Biophysica Acta (BBA) - Bioenergetics · doi:10.1016/s0005-2728(98)00039-5 · Cited by 162 · see citing works
Mulholland, M. R., Gobler, C. J., & Lee, C. (2002) · Limnology and Oceanography · doi:10.4319/lo.2002.47.4.1094 · Cited by 157 · see citing works
Self-citationEffects of major nutrient additions on metal uptake in phytoplankton
Wang, W., & Dei, R. C. H. (2001) · Environmental Pollution · doi:10.1016/s0269-7491(00)00071-3 · Cited by 146 · see citing works
NEW LIGHT ON THE SCALING OF METABOLIC RATE WITH THE SIZE OF ALGAE
Raven, J. A., & Kübler, J. E. (2002) · Journal of Phycology · doi:10.1046/j.1529-8817.2002.01125.x · Cited by 134 · see citing works
Pierson, L. S., Gaffney, T. D., Lam, S., et al. (1995) · FEMS Microbiology Letters · doi:10.1111/j.1574-6968.1995.tb07954.x · Cited by 130 · see citing works
Doblin, M. A., Blackburn, S. I., & Hallegraeff, G. M. (1999) · Journal of Experimental Marine Biology and Ecology · doi:10.1016/s0022-0981(98)00193-2 · Cited by 123 · see citing works
Photophysiology of the marine cyanobacterium Synechococcus sp. WH8102, a new model organism
Six, C., Thomas, J., Brahamsha, B., Lemoine, Y., & Partensky, F. (2004) · Aquatic Microbial Ecology · doi:10.3354/ame035017 · Cited by 111 · see citing works
Fan, C., Glibert, P. M., Alexander, J., & Lomas, M. W. (2003) · Marine Biology · doi:10.1007/s00227-003-1017-8 · Cited by 103 · see citing works
Survey of selenium requirements in marine phytoplankton
Harrison, P. J. H., Yu, P., THOMPSON, P. A., Price, N. M., & Phillips, D. (1988) · Marine Ecology Progress Series · doi:10.3354/meps047089 · Cited by 102 · see citing works
Doblin, M. A., Blackburn, S. I., & Hallegraeff, G. M. (1999) · Journal of Plankton Research · doi:10.1093/plankt/21.6.1153 · Cited by 98 · see citing works
Score, A. J., Palfreyman, J. W., & White, N. A. (1997) · International Biodeterioration & Biodegradation · doi:10.1016/s0964-8305(97)00012-7 · Cited by 87 · see citing works
Contrasting photoacclimation costs in ecotypes of the marine eukaryotic picoplankter Ostreococcus
Six, C., Finkel, Z. V., Rodríguez, F., et al. (2008) · Limnology and Oceanography · doi:10.4319/lo.2008.53.1.0255 · Cited by 81 · see citing works
VerBerkmoes, N. C., Shah, M. B., Lankford, P. K., Pelletier, D. A., Strader, M. B., Tabb, D. L., McDonald, W. H., Barton, J. W., Hurst, G. B., Hauser, L., et al. (2006) · Journal of Proteome Research · doi:10.1021/pr0503230 · Cited by 79 · see citing works
Self-citationMacIntyre, H. L., Lomas, M. W., Cornwell, J. C., Suggett, D. J., Gobler, C. J., Koch, E. W., & Kana, T. M. (2004) · Harmful Algae · doi:10.1016/j.hal.2004.05.005 · Cited by 78 · see citing works
Self-citationThe Alcaligenes eutrophus protein HoxN mediates nickel transport in Escherichia coli
Wolfram, L., Friedrich, B., & Eitinger, T. (1995) · Journal of Bacteriology · doi:10.1128/jb.177.7.1840-1843.1995 · Cited by 76 · see citing works
Eppard, M., & Rhiel, E. (1998) · Molecular and General Genetics MGG · doi:10.1007/s004380050902 · Cited by 69 · see citing works
Flegal, A. R., & Sañudo‐Wilhelmy, S. A. (1993) · Environmental Science & Technology · doi:10.1021/es00046a025 · Cited by 69 · see citing works
CORRELATED EVOLUTION OF GENOME SIZE AND CELL VOLUME IN DIATOMS (BACILLARIOPHYCEAE)1
Connolly, J. A., Oliver, M. J., Beaulieu, J. M., Knight, C. A., Tomanek, L., & Moline, M. A. (2008) · Journal of Phycology · doi:10.1111/j.1529-8817.2007.00452.x · Cited by 68 · see citing works
Wurch, L. L., Haley, S. T., Orchard, E. D., Gobler, C. J., & Dyhrman, S. T. (2010) · Environmental Microbiology · doi:10.1111/j.1462-2920.2010.02351.x · Cited by 64 · see citing works
Self-citationO’Kelly, C. J., Sieracki, M. E., Thier, E. C., et al. (2003) · Journal of Phycology · doi:10.1046/j.1529-8817.2003.02201.x · Cited by 64 · see citing works
Selenium biogeochemistry in the San Francisco Bay estuary: changes in water column behavior
Cutter, G. A., & Cutter, L. S. (2004) · Estuarine Coastal and Shelf Science · doi:10.1016/j.ecss.2004.06.011 · Cited by 58 · see citing works
Berg, G. M., Shrager, J., Glöckner, G., Arrigo, K. R., & Grossman, A. R. (2008) · Journal of Phycology · doi:10.1111/j.1529-8817.2008.00571.x · Cited by 55 · see citing works
Self-citationPierson, L. S. (1995) · FEMS Microbiology Letters · doi:10.1016/0378-1097(95)00423-x · Cited by 50 · see citing works
Eppard, M., Krumbein, W. E., von Haeseler, A., et al. (2000) · Plant Biology · doi:10.1055/s-2000-3702 · Cited by 47 · see citing works
Breuer, E., Sañudo‐Wilhelmy, S. A., Aller, R. C., & Sañudo‐Wilhelmy, S. A. (1999) · Estuaries · doi:10.2307/1353048 · Cited by 44 · see citing works
Signal transduction in the sexual life of Chlamydomonas
Quarmby, L. M. (1994) · Plant Molecular Biology · doi:10.1007/bf00016474 · Cited by 41 · see citing works
Pico- and nanoplankton dynamics during bloom initiation of Aureococcus in a Long Island, NY bay
Sieracki, M. E., Gobler, C. J., Cucci, T. L., Thier, E. C., Gilg, I. C., & Keller, M. D. (2004) · Harmful Algae · doi:10.1016/j.hal.2004.06.012 · Cited by 39 · see citing works
Self-citationPopels, L. C., MacIntyre, H. L., Warner, M. E., et al. (2007) · Journal of Phycology · doi:10.1111/j.1529-8817.2006.00303.x · Cited by 38 · see citing works
Stauffer, B., Schaffner, R. A., Wazniak, C. E., & Caron, D. A. (2008) · Applied and Environmental Microbiology · doi:10.1128/aem.00996-08 · Cited by 25 · see citing works
Lefebvre, S. C., Harris, G. N., Webster, R., et al. (2009) · Journal of Phycology · doi:10.1111/j.1529-8817.2009.00793.x · Cited by 23 · see citing works
Flagged first, then by citations
Research works printed but not linked: 1
- Gobler CJ, Lonsdale DJ, Boyer GL (2005) A synthesis and review of causes and impact of harmful brown tide blooms caused by the alga, Aureococcus anophagefferens. Estuaries 28:726-749.
Cited by
Sorted by citations
Algae as nutritional and functional food sources: revisiting our understanding.
Wells, M. L., Potin, P., Craigie, J. S., Raven, J. A., Merchant, S. S., Helliwell, K. E., Smith, A. G., Camire, M. E., & Brawley, S. H. (2017) · Journal of Applied Phycology · doi:10.1007/s10811-016-0974-5 · Cited by 1,562 · see citing works
Keeling, P. J., Burki, F., Wilcox, H. M., Allam, B., Allen, E. E., Amaral-Zettler, L. A., Armbrust, E. V., Archibald, J. M., Bharti, A. K., Bell, C. J., et al. (2014) · PLoS Biology · doi:10.1371/journal.pbio.1001889 · Cited by 1,042 · see citing works
Self-citationGenome editing of model oleaginous microalgae <i>Nannochloropsis</i> spp. by <scp>CRISPR</scp> /Cas9
Wang, Q., Lu, Y., Xin, Y., Wei, L., Huang, S., & Xu, J. (2016) · The Plant Journal · doi:10.1111/tpj.13307 · Cited by 312 · see citing works
Overcoming biological constraints to enable the exploitation of microalgae for biofuels
Day, J. G., Slocombe, S. P., & Stanley, M. S. (2012) · Bioresource Technology · doi:10.1016/j.biortech.2011.05.033 · Cited by 162 · see citing works
Mulholland, M. R., Morse, R., Egerton, T., Bernhardt, P. W., & Filippino, K. C. (2018) · Estuaries and Coasts · doi:10.1007/s12237-018-0388-5 · Cited by 64 · see citing works
A family of diatom-like silicon transporters in the siliceous loricate choanoflagellates
Marron, A. O., Alston, M. J., Heavens, D., Akam, M., Caccamo, M., Holland, P. W. H., & Walker, G. (2013) · Proceedings of the Royal Society B: Biological Sciences · doi:10.1098/rspb.2012.2543 · Cited by 54 · see citing works
- Authors
- Gobler, C. J., Berry, D. L., Dyhrman, S. T., Wilhelm, S. W., Salamov, A., Lobanov, A. V., Zhang, Y., Collier, J. L., Wurch, L. L., Kustka, A. B., Dill, B. D., Shah, M., VerBerkmoes, N. C., Kuo, A., Terry, A., Pangilinan, J., Lindquist, E. A., Lucas, S., Paulsen, I. T., Hattenrath-Lehmann, T. K., Talmage, S. C., Walker, E. A., Koch, F., Burson, A. M., Marcoval, M. A., Tang, Y.-Z., LeCleir, G. R., Coyne, K. J., Berg, G. M., Bertrand, E. M., Saito, M. A., Gladyshev, V. N., & Grigoriev, I. V.
- Affiliations
- Stony Brook University (US)
- Woods Hole Oceanographic Institution (US)
- University of Tennessee at Knoxville (US)
- Joint Genome Institute (US)
- Brigham and Women's Hospital (US)
- Rutgers, The State University of New Jersey (US)
- Chemical Sciences and
- Oak Ridge National Laboratory (US)
- Macquarie University (AU)
- University of Delaware (US)
- Stanford University (US)
- Massachusetts Institute of Technology (US)
- ORCID
- Gobler, Christopher J.
- Dyhrman, Sonya T.
- Wilhelm, Steven W.
- Salamov, Asaf
- Lobanov, Alexei V.
- Zhang, Yan
- Collier, Jackie L.
- Wurch, Louie L.
- Kustka, Adam B.
- Dill, Brian D.
- Shah, Manesh
- Kuo, Alan
- Terry, Astrid
- Pangilinan, Jasmyn
- Lindquist, Erika A.
- Lucas, Susan
- Paulsen, Ian T.
- Koch, Florian
- Burson, Amanda M.
- Marcoval, Maria Alejandra
- Tang, Ying-Zhong
- LeCleir, Gary R.
- Coyne, Kathryn J.
- Bertrand, Erin M.
- Saito, Mak A.
- Gladyshev, Vadim N.
- Grigoriev, Igor V.
- Venue
- Proceedings of the National Academy of Sciences
- Publisher
- National Academy of Sciences
- Published
- 2011-02-23
- Volume
- 108
- Issue
- 11
- Pages
- 4352-4357
- ISSN
- 0027-8424 (ISSN-L)
- 1091-6490
- PMC
- PMC3060233
- OpenAlex
- W1984643266
- Cited by
- 285
- References
- 86
- Citations by year
- 2026: 5 · 2025: 12 · 2024: 20 · 2023: 15 · 2022: 14 · 2021: 19 · 2020: 17 · 2019: 24 · 2018: 21 · 2017: 20 · 2016: 22 · 2015: 18 · 2014: 16 · 2013: 18 · 2012: 25
- FWCI
- 17.59
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- Proceedings of the National Academy of Sciences (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- OSTI OAI (U.S. Department of Energy Office of Scientific and Technical Information) (submittedVersion)
- University of North Texas Digital Library (University of North Texas) (submittedVersion)
- Open Access Server of the Woods Hole Scientific Community (Woods Hole Scientific Community) (submittedVersion)
- DSpace@MIT (Massachusetts Institute of Technology) (submittedVersion, cc-by-nc)
- eScholarship (California Digital Library) (submittedVersion)
- Funders
- National Science Foundation (DEAC02-05CH11231, 0841918)
- U.S. Department of Energy (-AC02-05CH11231, 05CH11231, DE-AC02-)
- Harvard University
- Joint Genome Institute (AC02-05CH11231, DE–AC02–05CH11231)
- Stony Brook University
- National Institutes of Health (DE-AC02–05CH11231)
- National Oceanic and Atmospheric Administration (DE-AC02-05CH11231, NA07OAR4170010, NA10OAR4170064, NA09NOS4780206)
- Office of Science (AC02-05CH11231, DE-AC02, 05CH11231)
- National Institute of General Medical Sciences (R01GM061603, GM061603)
- New York Sea Grant, State University of New York (NA07OAR4170010, NA10OAR4170064)
- Center for Sponsored Coastal Ocean Research
- Lawrence Livermore National Laboratory (DE-AC02-05CH11231)
- Topics
- Physical Sciences › Earth and Planetary Sciences › Oceanography › Marine and coastal ecosystems
- Physical Sciences › Environmental Science › Environmental Chemistry › Aquatic Ecosystems and Phytoplankton Dynamics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Protist diversity and phylogeny
- Keywords
- Aureococcus anophagefferens, harmful algal blooms, ecogenomics, phytoplankton competition, estuaries, dissolved organic matter, turbidity, dissolved inorganic nitrogen, genome size, anthropogenic impacts, coastal ecosystems
- MeSH terms
- Amino Acid Sequence, Bacteria, Biodegradation, Environmental, Enzymes, Light, Phylogeny, Phytoplankton, Proteins, Species Specificity, Genome, Ecosystem, Genomics, Eukaryota
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
