The DOI matches its Crossref record; 32 of the 32 references it cites were found in a registry or an index.
Brassinosteroid control of sex determination in maize
Open accessAbstract
Brassinosteroids (BRs) are plant hormones that regulate growth and development. They share structural similarities with animal steroids, which are decisive factors of sex determination. BRs are known to regulate morphogenesis and environmental stress responses, but their involvement in sex determination in plants has been only speculative. We show that BRs control sex determination in maize revealed through characterization of the classical dwarf mutant nana plant1 ( na1 ), which also feminizes male flowers. na1 plants carry a loss-of-function mutation in a DET2 homolog—a gene in the BR biosynthetic pathway. The mutant accumulates the DET2-specific substrate ( 24R )-24-methylcholest-4-en-3-one with a concomitant decrease of downstream BR metabolites. Treatment of wild-type maize plants with BR biosynthesis inhibitors completely mimicked both dwarf and tasselseed phenotypes of na1 mutants. Tissue-specific na1 expression in anthers throughout their development supports the hypothesis that BRs promote masculinity of the male inflorescence. These findings suggest that, in the monoecious plant maize, BRs have been coopted to perform a sex determination function not found in plants with bisexual flowers.
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Cited by
Brassinosteroid Signaling Network and Regulation of Photomorphogenesis
Wang, Z.-Y., Bai, M.-Y., Oh, E., & Zhu, J.-Y. (2012) · Annual Review of Genetics · doi:10.1146/annurev-genet-102209-163450 · Cited by 490
Metabolomics for Plant Improvement: Status and Prospects
Kumar, R., Bohra, A., Pandey, A. K., Pandey, M. K., & Kumar, A. (2017) · Frontiers in Plant Science · doi:10.3389/fpls.2017.01302 · Cited by 328
Ghesmati, Z., Rashid, M., Fayezi, S., Gieseler, F., Alizadeh, E., & Darabi, M. (2024) · Reviews in Endocrine and Metabolic Disorders · doi:10.1007/s11154-023-09850-0 · Cited by 139
Brassinosteroid action in flowering plants: A Darwinian perspective
Kutschera, U., & Wang, Z.-Y. (2012) · Journal of Experimental Botany · doi:10.1093/jxb/ers065 · Cited by 77
Metadata
- Authors
- Hartwig, T., Chuck, G. S., Fujioka, S., Klempien, A., Weizbauer, R., Potluri, D. P. V., Choe, S., Johal, G. S., & Schulz, B.
- Venue
- Proceedings of the National Academy of Sciences
- Published
- 2011-11-21
- Volume
- 108
- Issue
- 49
- Pages
- 19814-19819
- ISSN
- 0027-8424 (ISSN-L)
- 1091-6490
- OpenAlex
- W2159729657
- Cited by
- 265
- References
- 32
- FWCI
- 11.99
- Type
- journal article
- Language
- en
- Open access
- green
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- Hartwig, T., Chuck, G. S., Fujioka, S., Klempien, A., Weizbauer, R., Potluri, D. P. V., Choe, S., Johal, G. S., & Schulz, B. (2011). Brassinosteroid control of sex determination in maize. Proceedings of the National Academy of Sciences. https://doi.org/10.1073/pnas.1108359108
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