The DOI matches its Crossref record; 59 of the 59 references it cites were found in a registry or an index.
Brassinosteroids inhibit pathogen-associated molecular pattern–triggered immune signaling independent of the receptor kinase BAK1
Open accessAbstract
Plants and animals use innate immunity as a first defense against pathogens, a costly yet necessary tradeoff between growth and immunity. In Arabidopsis , the regulatory leucine-rich repeat receptor-like kinase (LRR-RLK) BAK1 combines with the LRR-RLKs FLS2 and EFR in pathogen-associated molecular pattern (PAMP)-triggered immunity (PTI) and the LRR-RLK BRI1 in brassinosteroid (BR)-mediated growth. Therefore, a potential tradeoff between these pathways mediated by BAK1 is often postulated. Here, we show a unidirectional inhibition of FLS2-mediated immune signaling by BR perception. Unexpectedly, this effect occurred downstream or independently of complex formation with BAK1 and associated downstream phosphorylation. Thus, BAK1 is not rate-limiting in these pathways. BRs also inhibited signaling triggered by the BAK1-independent recognition of the fungal PAMP chitin. Our results suggest a general mechanism operative in plants in which BR-mediated growth directly antagonizes innate immune signaling.
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A Plant miRNA Contributes to Antibacterial Resistance by Repressing Auxin Signaling
Navarro, L., Dunoyer, P., Jay, F., Arnold, B., Dharmasiri, N., Estelle, M., Voinnet, O., & Jones, J. D. G. (2006) · Science · doi:10.1126/science.1126088 · Cited by 1,971
A flagellin-induced complex of the receptor FLS2 and BAK1 initiates plant defence
Chinchilla, D., Zipfel, C., Robatzek, S., Kemmerling, B., Nürnberger, T., Jones, J. D. G., Felix, G., & Boller, T. (2007) · Nature · doi:10.1038/nature05999 · Cited by 1,923
Self-citationBacterial disease resistance in Arabidopsis through flagellin perception
Zipfel, C., Robatzek, S., Navarro, L., Oakeley, E. J., Jones, J. D. G., Felix, G., & Boller, T. (2004) · Nature · doi:10.1038/nature02485 · Cited by 1,790
Self-citationIntegration of Plant Responses to Environmentally Activated Phytohormonal Signals
Achard, P., Cheng, H., De Grauwe, L., Decat, J., Schoutteten, H., Moritz, T., Van Der Straeten, D., Peng, J., & Harberd, N. P. (2006) · Science · doi:10.1126/science.1118642 · Cited by 1,552
Li, J., Wen, J., Lease, K. A., Doke, J. T., Tax, F. E., & Walker, J. C. (2002) · Cell · doi:10.1016/s0092-8674(02)00812-7 · Cited by 1,446
CERK1, a LysM receptor kinase, is essential for chitin elicitor signaling in Arabidopsis
Miya, A., Albert, P., Shinya, T., Desaki, Y., Ichimura, K., Shirasu, K., Narusaka, Y., Kawakami, N., Kaku, H., & Shibuya, N. (2007) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0705147104 · Cited by 1,427
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BRI1/BAK1, a Receptor Kinase Pair Mediating Brassinosteroid Signaling
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The receptor-like kinase SERK3/BAK1 is a central regulator of innate immunity in plants
Heese, A., Hann, D. R., Gimenez-Ibanez, S., Jones, A. M. E., He, K., Li, J., Schroeder, J. I., Peck, S. C., & Rathjen, J. P. (2007) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0705306104 · Cited by 1,146
Self-citation
Cited by
Plant PRRs and the Activation of Innate Immune Signaling
Macho, A. P., & Zipfel, C. (2014) · Molecular Cell · doi:10.1016/j.molcel.2014.03.028 · Cited by 989
Self-citationThirty years of resistance: Zig-zag through the plant immune system
Ngou, B. P. M., Ding, P., & Jones, J. D. G. (2022) · The Plant Cell · doi:10.1093/plcell/koac041 · Cited by 961
Xia, X.-J., Zhou, Y.-H., Shi, K., Zhou, J., Foyer, C. H., & Yu, J.-Q. (2015) · Journal of Experimental Botany · doi:10.1093/jxb/erv089 · Cited by 709
Light Regulation of Plant Defense
Ballaré, C. L. (2014) · Annual Review of Plant Biology · doi:10.1146/annurev-arplant-050213-040145 · Cited by 560
Brassinosteroid Signaling Network and Regulation of Photomorphogenesis
Wang, Z.-Y., Bai, M.-Y., Oh, E., & Zhu, J.-Y. (2012) · Annual Review of Genetics · doi:10.1146/annurev-genet-102209-163450 · Cited by 490
Metadata
- Authors
- Albrecht, C., Boutrot, F., Segonzac, C., Schwessinger, B., Gimenez-Ibanez, S., Chinchilla, D., Rathjen, J. P., de Vries, S. C., & Zipfel, C.
- Venue
- Proceedings of the National Academy of Sciences
- Published
- 2011-10-27
- Volume
- 109
- Issue
- 1
- Pages
- 303-308
- ISSN
- 0027-8424 (ISSN-L)
- 1091-6490
- OpenAlex
- W2158612914
- Cited by
- 339
- References
- 59
- FWCI
- 38.51
- Type
- journal article
- Language
- en
- Open access
- green
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- Albrecht, C., Boutrot, F., Segonzac, C., Schwessinger, B., Gimenez-Ibanez, S., Chinchilla, D., Rathjen, J. P., de Vries, S. C., & Zipfel, C. (2012). Brassinosteroids inhibit pathogen-associated molecular pattern–triggered immune signaling independent of the receptor kinase BAK1. Proceedings of the National Academy of Sciences. https://doi.org/10.1073/pnas.1109921108
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