The DOI matches its Crossref record; 53 of the 53 references it cites were found in a registry or an index.
Plant hormone jasmonate prioritizes defense over growth by interfering with gibberellin signaling cascade
Open accessAbstract
Plants must effectively defend against biotic and abiotic stresses to survive in nature. However, this defense is costly and is often accompanied by significant growth inhibition. How plants coordinate the fluctuating growth-defense dynamics is not well understood and remains a fundamental question. Jasmonate (JA) and gibberellic acid (GA) are important plant hormones that mediate defense and growth, respectively. Binding of bioactive JA or GA ligands to cognate receptors leads to proteasome-dependent degradation of specific transcriptional repressors (the JAZ or DELLA family of proteins), which, at the resting state, represses cognate transcription factors involved in defense (e.g., MYCs) or growth [e.g. phytochrome interacting factors (PIFs)]. In this study, we found that the coi1 JA receptor mutants of rice (a domesticated monocot crop) and Arabidopsis (a model dicot plant) both exhibit hallmark phenotypes of GA-hypersensitive mutants. JA delays GA-mediated DELLA protein degradation, and the della mutant is less sensitive to JA for growth inhibition. Overexpression of a selected group of JAZ repressors in Arabidopsis plants partially phenocopies GA-associated phenotypes of the coi1 mutant, and JAZ9 inhibits RGA (a DELLA protein) interaction with transcription factor PIF3. Importantly, the pif quadruple ( pifq ) mutant no longer responds to JA-induced growth inhibition, and overexpression of PIF3 could partially overcome JA-induced growth inhibition. Thus, a molecular cascade involving the COI1–JAZ–DELLA–PIF signaling module, by which angiosperm plants prioritize JA-mediated defense over growth, has been elucidated.
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JAZ repressor proteins are targets of the SCFCOI1 complex during jasmonate signalling
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Self-citationThe JAZ family of repressors is the missing link in jasmonate signalling
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Gibberellin Metabolism and its Regulation
Yamaguchi, S. (2008) · Annual Review of Plant Biology · doi:10.1146/annurev.arplant.59.032607.092804 · Cited by 2,194
COI1 : An Arabidopsis Gene Required for Jasmonate-Regulated Defense and Fertility
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A molecular framework for light and gibberellin control of cell elongation
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The Arabidopsis GAI gene defines a signaling pathway that negatively regulates gibberellin responses
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Cited by
Wasternack, C., & Hause, B. (2013) · Annals of Botany · doi:10.1093/aob/mct067 · Cited by 2,629
Züst, T., & Agrawal, A. A. (2017) · Annual Review of Plant Biology · doi:10.1146/annurev-arplant-042916-040856 · Cited by 624
Brassinosteroid Signaling Network and Regulation of Photomorphogenesis
Wang, Z.-Y., Bai, M.-Y., Oh, E., & Zhu, J.-Y. (2012) · Annual Review of Genetics · doi:10.1146/annurev-genet-102209-163450 · Cited by 490
Molecular mechanism of strigolactone perception by DWARF14
Nakamura, H., Xue, Y.-L., Miyakawa, T., Hou, F., Qin, H.-M., Fukui, K., Shi, X., Ito, E., Ito, S., Park, S.-H., et al. (2013) · Nature Communications · doi:10.1038/ncomms3613 · Cited by 378
Resolution of growth–defense conflict: mechanistic insights from jasmonate signaling
Guo, Q., Major, I. T., & Howe, G. A. (2018) · Current Opinion in Plant Biology · doi:10.1016/j.pbi.2018.02.009 · Cited by 292
Metadata
- Authors
- Yang, D.-L., Yao, J., Mei, C.-S., Tong, X.-H., Zeng, L.-J., Li, Q., Xiao, L.-T., Sun, T.-P., Li, J., Deng, X.-W., Lee, C. M., Thomashow, M. F., Yang, Y., He, Z., & He, S. Y.
- Venue
- Proceedings of the National Academy of Sciences
- Published
- 2012-04-23
- Volume
- 109
- Issue
- 19
- Pages
- E1192-200
- ISSN
- 0027-8424 (ISSN-L)
- 1091-6490
- OpenAlex
- W2065813460
- Cited by
- 873
- References
- 53
- FWCI
- 61.58
- Type
- journal article
- Language
- en
- Open access
- green
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- Yang, D.-L., Yao, J., Mei, C.-S., Tong, X.-H., Zeng, L.-J., Li, Q., Xiao, L.-T., Sun, T.-P., Li, J., Deng, X.-W., Lee, C. M., Thomashow, M. F., Yang, Y., He, Z., & He, S. Y. (2012). Plant hormone jasmonate prioritizes defense over growth by interfering with gibberellin signaling cascade. Proceedings of the National Academy of Sciences. https://doi.org/10.1073/pnas.1201616109
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