Molecular mechanism of strigolactone perception by DWARF14
Open accessAbstract
Strigolactones (SLs) are phytohormones that inhibit shoot branching and function in the rhizospheric communication with symbiotic fungi and parasitic weeds. An α/β-hydrolase protein, DWARF14 (D14), has been recognized to be an essential component of plant SL signalling, although its precise function remains unknown. Here we present the SL-dependent interaction of D14 with a gibberellin signalling repressor SLR1 and a possible mechanism of phytohormone perception in D14-mediated SL signalling. D14 functions as a cleavage enzyme of SLs, and the cleavage reaction induces the interaction with SLR1. The crystal structure of D14 shows that 5-hydroxy-3-methylbutenolide (D-OH), which is a reaction product of SLs, is trapped in the catalytic cavity of D14 to form an altered surface. The D14 residues recognizing D-OH are critical for the SL-dependent D14-SLR1 interaction. These results provide new insight into crosstalk between gibberellin and SL signalling pathways.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
Three different candidate repressors for the strigolactone signaling pathway have been identified: DELLA proteins, BES1, and D53.
“Indeed, three different candidate repressors for the strigoalactone signaling pathway have been identified: DELLA proteins (Nakamura et al., 2013), BES1 (Wang et al., 2013), and D53 in rice (Jiang et al., 2013; Zhou et al., 2013).”
From Shaping plant architecture (2015) · cites this paper as Nakamura et al., 2013
Cites
<i>Coot</i> : model-building tools for molecular graphics
Emsley, P., & Cowtan, K. (2004) · Acta Crystallographica Section D Biological Crystallography · doi:10.1107/s0907444904019158 · Cited by 30,571 · see citing works
PROCHECK: a program to check the stereochemical quality of protein structures
Laskowski, R. A., MacArthur, M. W., Moss, D. S., & Thornton, J. M. (1993) · Journal of Applied Crystallography · doi:10.1107/s0021889892009944 · Cited by 24,581 · see citing works
Refinement of Macromolecular Structures by the Maximum-Likelihood Method
Murshudov, G. N., Vagin, A. A., & Dodson, E. J. (1997) · Acta Crystallographica Section D Biological Crystallography · doi:10.1107/s0907444996012255 · Cited by 14,671 · see citing works
Kabsch, W. (1993) · Journal of Applied Crystallography · doi:10.1107/s0021889893005588 · Cited by 3,562 · see citing works
Plant sesquiterpenes induce hyphal branching in arbuscular mycorrhizal fungi
Akiyama, K., Matsuzaki, K.-I., & Hayashi, H. (2005) · Nature · doi:10.1038/nature03608 · Cited by 2,429 · see citing works
Strigolactone inhibition of shoot branching
Gomez-Roldan, V., Fermas, S., Brewer, P. B., Puech-Pagès, V., Dun, E. A., Pillot, J.-P., Letisse, F., Matusova, R., Danoun, S., Portais, J.-C., et al. (2008) · Nature · doi:10.1038/nature07271 · Cited by 2,281 · see citing works
Inhibition of shoot branching by new terpenoid plant hormones
Umehara, M., Hanada, A., Yoshida, S., Akiyama, K., Arite, T., Takeda-Kamiya, N., Magome, H., Kamiya, Y., Shirasu, K., Yoneyama, K., et al. (2008) · Nature · doi:10.1038/nature07272 · Cited by 2,105 · see citing works
Nakagawa, T., Kurose, T., Hino, T., Tanaka, K., Kawamukai, M., Niwa, Y., Toyooka, K., Matsuoka, K., Jinbo, T., & Kimura, T. (2007) · Journal of Bioscience and Bioengineering · doi:10.1263/jbb.104.34 · Cited by 1,644 · see citing works
GIBBERELLIN INSENSITIVE DWARF1 encodes a soluble receptor for gibberellin
Ueguchi‐Tanaka, M., Ashikari, M., Nakajima, M., Itoh, H., Katoh, E., Kobayashi, M., Chow, T., Hsing, Y.-I. C., Kitano, H., Yamaguchi, I., et al. (2005) · Nature · doi:10.1038/nature04028 · Cited by 1,313 · see citing works
Germination of Witchweed ( Striga lutea Lour.): Isolation and Properties of a Potent Stimulant
Cook, C. E., Whichard, L. P., Turner, B., Wall, M. E., & Egley, G. H. (1966) · Science · doi:10.1126/science.154.3753.1189 · Cited by 1,040 · see citing works
The Path from β-Carotene to Carlactone, a Strigolactone-Like Plant Hormone
Alder, A., Jamil, M., Marzorati, M., Bruno, M., Vermathen, M., Bigler, P., Ghisla, S., Bouwmeester, H. J., Beyer, P., & Al‐Babili, S. (2012) · Science · doi:10.1126/science.1218094 · Cited by 930 · see citing works
Yang, D., Yao, J., Mei, C.-S., et al. (2012) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1201616109 · Cited by 876 · see citing works
DELLAs Modulate Jasmonate Signaling via Competitive Binding to JAZs
Hou, X., Lee, L. Y. C., Xia, K., et al. (2010) · Developmental Cell · doi:10.1016/j.devcel.2010.10.024 · Cited by 814 · see citing works
Silverstone, A. L., Ciampaglio, C. N., & Sun, T. (1998) · The Plant Cell · doi:10.1105/tpc.10.2.155 · Cited by 807 · see citing works
<i>MAX1</i> and <i>MAX2</i> control shoot lateral branching in <i>Arabidopsis</i>
Stirnberg, P., van de Sande, K., & Leyser, H. M. O. (2002) · Development · doi:10.1242/dev.129.5.1131 · Cited by 692 · see citing works
Brassinosteroid, gibberellin and phytochrome impinge on a common transcription module in Arabidopsis
Bai, M., Shang, J., Oh, E., Fan, M., Bai, Y., Zentella, R., Sun, T., & Wang, Z. (2012) · Nature Cell Biology · doi:10.1038/ncb2546 · Cited by 684 · see citing works
d14, a Strigolactone-Insensitive Mutant of Rice, Shows an Accelerated Outgrowth of Tillers
Arite, T., Umehara, M., Ishikawa, S., Hanada, A., Maekawa, M., Yamaguchi, S., & Kyozuka, J. (2009) · Plant and Cell Physiology · doi:10.1093/pcp/pcp091 · Cited by 647 · see citing works
Hamiaux, C., Drummond, R. S. M., Janssen, B. J., Ledger, S. E., Cooney, J. M., Newcomb, R. D., & Snowden, K. C. (2012) · Current Biology · doi:10.1016/j.cub.2012.08.007 · Cited by 623 · see citing works
Observations on the current status of Orobanche and Striga problems worldwide
Parker, C. (2009) · Pest Management Science · doi:10.1002/ps.1713 · Cited by 546 · see citing works
ORE9, an F-Box Protein That Regulates Leaf Senescence in Arabidopsis
Woo, H. R., Chung, K. M., Park, J., Oh, S. A., Ahn, T., Hong, S. H., Jang, S. K., & Nam, H. G. (2001) · The Plant Cell · doi:10.1105/tpc.010061 · Cited by 535 · see citing works
Waters, M. T., Nelson, D. C., Scaffidi, A., Flematti, G. R., Sun, Y. K., Dixon, K. W., & Smith, S. M. (2012) · Development · doi:10.1242/dev.074567 · Cited by 530 · see citing works
Suppression of Tiller Bud Activity in Tillering Dwarf Mutants of Rice
Ishikawa, S., Maekawa, M., Arite, T., Onishi, K., Takamure, I., & Kyozuka, J. (2005) · Plant and Cell Physiology · doi:10.1093/pcp/pci022 · Cited by 526 · see citing works
Lo, S., Yang, S.-Y., Chen, K., Hsing, Y.-I. C., Zeevaart, J. A. D., Chen, L., & Yu, S. (2008) · The Plant Cell · doi:10.1105/tpc.108.060913 · Cited by 523 · see citing works
Strigolactones affect lateral root formation and root-hair elongation in Arabidopsis
Kapulnik, Y., Delaux, P.-M., Resnick, N., Mayzlish-Gati, E., Wininger, S., Bhattacharya, C., Séjalon-Delmas, N., Combier, J.-P., Bécard, G., Belausov, E., et al. (2011) · Planta · doi:10.1007/s00425-010-1310-y · Cited by 502 · see citing works
Ueda, T., Yamaguchi, M., Uchimiya, H., et al. (2001) · The EMBO Journal · doi:10.1093/emboj/20.17.4730 · Cited by 492 · see citing works
Self-citationF-box protein MAX2 has dual roles in karrikin and strigolactone signaling in Arabidopsis thaliana
Nelson, D. C., Scaffidi, A., Dun, E. A., Waters, M. T., Flematti, G. R., Dixon, K. W., Beveridge, C. A., Ghisalberti, E. L., & Smith, S. M. (2011) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1100987108 · Cited by 456 · see citing works
MAX2 participates in an SCF complex which acts locally at the node to suppress shoot branching
Stirnberg, P., Furner, I. J., & Ottoline Leyser, H. M. (2007) · The Plant Journal · doi:10.1111/j.1365-313x.2007.03032.x · Cited by 429 · see citing works
Strigolactones: Chemical Signals for Fungal Symbionts and Parasitic Weeds in Plant Roots
Akiyama, K., & Hayashi, H. (2006) · Annals of Botany · doi:10.1093/aob/mcl063 · Cited by 406 · see citing works
Gallego‐Bartolomé, J., Minguet, E. G., Enguix, F. G., Abbas, M., Locascio, A., Thomas, S. G., Alabadı́, D., & Blázquez, M. A. (2012) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1119992109 · Cited by 374 · see citing works
Hormonal control of shoot branching
Ongaro, V., & Leyser, O. (2007) · Journal of Experimental Botany · doi:10.1093/jxb/erm134 · Cited by 373 · see citing works
Structural Requirements of Strigolactones for Hyphal Branching in AM Fungi
Akiyama, K., Ogasawara, S., Ito, S., et al. (2010) · Plant and Cell Physiology · doi:10.1093/pcp/pcq058 · Cited by 355 · see citing works
Self-citationStrigolactones Suppress Adventitious Rooting in Arabidopsis and Pea
Rasmussen, A., Mason, M. G., Cuyper, C. D., Brewer, P. B., Herold, S., Agustí, J., Geelen, D., Greb, T., Goormachtig, S., Beeckman, T., et al. (2012) · PLANT PHYSIOLOGY · doi:10.1104/pp.111.187104 · Cited by 328 · see citing works
Johnson, X., Brcich, T., Dun, E. A., Goussot, M., Haurogné, K., Beveridge, C. A., & Rameau, C. (2006) · Plant Physiology · doi:10.1104/pp.106.087676 · Cited by 319 · see citing works
Strigolactones as Germination Stimulants for Root Parasitic Plants
Yoneyama, K., Yoneyama, K., Awad, A., et al. (2010) · Plant and Cell Physiology · doi:10.1093/pcp/pcq055 · Cited by 282 · see citing works
Wang, Y., & Li, J. (2010) · Current Opinion in Plant Biology · doi:10.1016/j.pbi.2010.11.002 · Cited by 265 · see citing works
Thermoinhibition Uncovers a Role for Strigolactones in Arabidopsis Seed Germination
Toh, S., Kamiya, Y., Kawakami, N., et al. (2011) · Plant and Cell Physiology · doi:10.1093/pcp/pcr176 · Cited by 248 · see citing works
Zhao, L., Zhou, X. E., Wu, Z., Yi, W., Xu, Y., Li, S., Xu, T.-H., Liu, Y., Chen, R.-Z., Kovach, A., et al. (2013) · Cell Research · doi:10.1038/cr.2013.19 · Cited by 243 · see citing works
Kagiyama, M., Hirano, Y., Mori, T., Kim, S., Kyozuka, J., Seto, Y., Yamaguchi, S., & Hakoshima, T. (2013) · Genes to Cells · doi:10.1111/gtc.12025 · Cited by 240 · see citing works
A small-molecule screen identifies new functions for the plant hormone strigolactone
Tsuchiya, Y., Vidaurre, D. P., Toh, S., Hanada, A., Nambara, E., Kamiya, Y., Yamaguchi, S., & McCourt, P. (2010) · Nature Chemical Biology · doi:10.1038/nchembio.435 · Cited by 238 · see citing works
The F-Box Protein MAX2 Functions as a Positive Regulator of Photomorphogenesis in Arabidopsis
Shen, H., Luong, P., & Huq, E. (2007) · PLANT PHYSIOLOGY · doi:10.1104/pp.107.107227 · Cited by 207 · see citing works
Boyer, F., Germain, A. D. S., Pillot, J.-P., Pouvreau, J., Chen, V. X., Ramos, S., Stévenin, A., Simier, P., Delavault, P. M., Beau, J., et al. (2012) · PLANT PHYSIOLOGY · doi:10.1104/pp.112.195826 · Cited by 188 · see citing works
ORE9, an F-Box Protein That Regulates Leaf Senescence in Arabidopsis
Woo, H. R. (2001) · The Plant Cell · doi:10.1105/tpc.13.8.1779 · Cited by 183 · see citing works
Liu, W., Wu, C., Fu, Y., Hu, G., Si, H., Zhu, L., Luan, W., He, Z., & Sun, Z. (2009) · Planta · doi:10.1007/s00425-009-0975-6 · Cited by 174 · see citing works
Dwarf 88, a novel putative esterase gene affecting architecture of rice plant
Gao, Z., Qian, Q., Liu, X., Yan, M., Feng, Q., Dong, G., Liu, J., & Han, B. (2009) · Plant Molecular Biology · doi:10.1007/s11103-009-9522-x · Cited by 173 · see citing works
Axillary bud outgrowth: sending a message
Beveridge, C. A. (2006) · Current Opinion in Plant Biology · doi:10.1016/j.pbi.2005.11.006 · Cited by 168 · see citing works
Mangnus, E. M., Dommerholt, F. J., Jong, R. L. P. D., et al. (1992) · Journal of Agricultural and Food Chemistry · doi:10.1021/jf00019a031 · Cited by 154 · see citing works
Goh, T., Uchida, W., Arakawa, S., Ito, E., Dainobu, T., Ebine, K., Takeuchi, M., Sato, K., Ueda, T., & Nakano, A. (2007) · The Plant Cell · doi:10.1105/tpc.107.053876 · Cited by 138 · see citing works
Self-citationDynamic behavior of clathrin in Arabidopsis thaliana unveiled by live imaging
Ito, E., Fujimoto, M., Ebine, K., et al. (2011) · The Plant Journal · doi:10.1111/j.1365-313x.2011.04782.x · Cited by 125 · see citing works
Self-citationMAX2 Affects Multiple Hormones to Promote Photomorphogenesis
Shen, H., Zhu, L. Q., Bu, Q.-Y., & Huq, E. (2012) · Molecular Plant · doi:10.1093/mp/sss029 · Cited by 124 · see citing works
Plant ubiquitin-proteasome pathway and its role in gibberellin signaling
Wang, F., & Deng, X. W. (2011) · Cell Research · doi:10.1038/cr.2011.118 · Cited by 116 · see citing works
New branching inhibitors and their potential as strigolactone mimics in rice
Fukui, K., Ito, S., Ueno, K., et al. (2011) · Bioorganic & Medicinal Chemistry Letters · doi:10.1016/j.bmcl.2011.06.019 · Cited by 112 · see citing works
Self-citationHu, Z., Yan, H., Yang, J., Yamaguchi, S., Maekawa, M., Takamure, I., Tsutsumi, N., Kyozuka, J., & Nakazono, M. (2010) · Plant and Cell Physiology · doi:10.1093/pcp/pcq075 · Cited by 102 · see citing works
Exploring the molecular mechanism of karrikins and strigolactones
Scaffidi, A., Waters, M. T., Bond, C. S., Dixon, K. W., Smith, S. M., Ghisalberti, E. L., & Flematti, G. R. (2012) · Bioorganic & Medicinal Chemistry Letters · doi:10.1016/j.bmcl.2012.04.016 · Cited by 75 · see citing works
A New Lead Chemical for Strigolactone Biosynthesis Inhibitors
Ito, S., Kitahata, N., Umehara, M., et al. (2010) · Plant and Cell Physiology · doi:10.1093/pcp/pcq077 · Cited by 53 · see citing works
Self-citationCrystal structures of RsbQ, a stress‐response regulator in Bacillus subtilis
Kaneko, T., Tanaka, N., & Kumasaka, T. (2005) · Protein Science · doi:10.1110/ps.041170005 · Cited by 51 · see citing works
Flagged first, then by citations
Cited by
Sorted by citations
Strigolactones, a Novel Carotenoid-Derived Plant Hormone
Al‐Babili, S., & Bouwmeester, H. J. (2015) · Annual Review of Plant Biology · doi:10.1146/annurev-arplant-043014-114759 · Cited by 836 · see citing works
D14–SCFD3-dependent degradation of D53 regulates strigolactone signalling
Zhou, F., Lin, Q., Zhu, L., Ren, Y., Zhou, K., Shabek, N., Wu, F., Mao, H., Dong, W., Gan, L., et al. (2013) · Nature · doi:10.1038/nature12878 · Cited by 891 · see citing works
Self-citationStrigolactone Signaling and Evolution
Waters, M. T., Gutjahr, C., Bennett, T., & Nelson, D. C. (2017) · Annual Review of Plant Biology · doi:10.1146/annurev-arplant-042916-040925 · Cited by 655 · see citing works
DWARF14 is a non-canonical hormone receptor for strigolactone
Yao, R., Ming, Z., Yan, L., Li, S., Wang, F., Ma, S., Yu, C., Yang, M., Chen, L., Chen, L., et al. (2016) · Nature · doi:10.1038/nature19073 · Cited by 535 · see citing works
A Pivotal Role of DELLAs in Regulating Multiple Hormone Signals
Davière, J., & Achard, P. (2015) · Molecular Plant · doi:10.1016/j.molp.2015.09.011 · Cited by 459 · see citing works
Abe, S., Sado, A., Tanaka, K., Kisugi, T., Asami, K., Ota, S., Kim, H. I., Yoneyama, K., Xie, X., Ohnishi, T., et al. (2014) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1410801111 · Cited by 425 · see citing works
Soundappan, I., Bennett, T., Morffy, N., Liang, Y., Stanga, J. P., Abbas, A., Leyser, O., & Nelson, D. C. (2015) · The Plant Cell · doi:10.1105/tpc.15.00562 · Cited by 424 · see citing works
Song, X., Lu, Z., Yu, H. J., Shao, G., Xiong, J., Meng, X., Jing, Y., Liu, G., Xiong, G., Duan, J., et al. (2017) · Cell Research · doi:10.1038/cr.2017.102 · Cited by 315 · see citing works
Scaffidi, A., Waters, M. T., Sun, Y. K., Skelton, B. W., Dixon, K. W., Ghisalberti, E. L., Flematti, G. R., & Smith, S. M. (2014) · PLANT PHYSIOLOGY · doi:10.1104/pp.114.240036 · Cited by 302 · see citing works
Convergent evolution of strigolactone perception enabled host detection in parasitic plants
Conn, C. E., Bythell‐Douglas, R., Neumann, D. A., Yoshida, S., Whittington, B., Westwood, J. H., Shirasu, K., Bond, C. S., Dyer, K. A., & Nelson, D. C. (2015) · Science · doi:10.1126/science.aab1140 · Cited by 300 · see citing works
An histidine covalent receptor and butenolide complex mediates strigolactone perception
Germain, A. D. S., Clavé, G., Badet‐Denisot, M., Pillot, J.-P., Cornu, D., Caër, J. L., Bürger, M., Pélissier, F., Retailleau, P., Turnbull, C. G. N., et al. (2016) · Nature Chemical Biology · doi:10.1038/nchembio.2147 · Cited by 276 · see citing works
Antagonistic Regulation of ABA and GA in Metabolism and Signaling Pathways
Liu, X., & Hou, X. (2018) · Frontiers in Plant Science · doi:10.3389/fpls.2018.00251 · Cited by 263 · see citing works
Strigolactone Regulates Leaf Senescence in Concert with Ethylene in Arabidopsis
Ueda, H., & Kusaba, M. (2015) · PLANT PHYSIOLOGY · doi:10.1104/pp.15.00325 · Cited by 253 · see citing works
Strigolactone perception and deactivation by a hydrolase receptor DWARF14
Seto, Y., Yasui, R., Kameoka, H., et al. (2019) · Nature Communications · doi:10.1038/s41467-018-08124-7 · Cited by 248 · see citing works
Strigolactones and the control of plant development: lessons from shoot branching
Waldie, T., McCulloch, H., & Leyser, O. (2014) · The Plant Journal · doi:10.1111/tpj.12488 · Cited by 242 · see citing works
Chevalier, F., Nieminen, K. M., Sánchez-Ferrero, J. C., Rodríguez, M. L., Chagoyen, M., Hardtke, C. S., & Cubas, P. (2014) · The Plant Cell · doi:10.1105/tpc.114.122903 · Cited by 239 · see citing works
Teichmann, T., & Muhr, M. (2015) · Frontiers in Plant Science · doi:10.3389/fpls.2015.00233 · Cited by 228 · see citing works
“Indeed, three different candidate repressors for the strigoalactone signaling pathway have been identified: DELLA proteins (Nakamura et al., 2013), BES1 (Wang et al., 2013), and D53 in rice (Jiang et al., 2013; Zhou et al., 2013).”
BackgroundSLR1 inhibits MOC1 degradation to coordinate tiller number and plant height in rice
Liao, Z., Yu, H. J., Duan, J., et al. (2019) · Nature Communications · doi:10.1038/s41467-019-10667-2 · Cited by 236 · see citing works
Liu, J., Cheng, X., Liu, P., & Sun, J. (2017) · PLANT PHYSIOLOGY · doi:10.1104/pp.17.00445 · Cited by 234 · see citing works
Strigolactone biosynthesis, transport and perception
Mashiguchi, K., Seto, Y., & Yamaguchi, S. (2020) · The Plant Journal · doi:10.1111/tpj.15059 · Cited by 226 · see citing works
Fang, Z., Ji, Y., Hu, J., Guo, R., Sun, S., & Wang, X. (2019) · Molecular Plant · doi:10.1016/j.molp.2019.12.005 · Cited by 228 · see citing works
Phytohormone signaling in arbuscular mycorhiza development
Gutjahr, C. (2014) · Current Opinion in Plant Biology · doi:10.1016/j.pbi.2014.04.003 · Cited by 218 · see citing works
Strigolactones in Plant Interactions with Beneficial and Detrimental Organisms: The Yin and Yang
Lopez-Raez, J. A., Shirasu, K., & Foo, E. (2017) · Trends in Plant Science · doi:10.1016/j.tplants.2017.03.011 · Cited by 211 · see citing works
Structural plasticity of D3–D14 ubiquitin ligase in strigolactone signalling
Shabek, N., Ticchiarelli, F., Mao, H., Hinds, T. R., Leyser, O., & Zheng, N. (2018) · Nature · doi:10.1038/s41586-018-0743-5 · Cited by 199 · see citing works
Regulation of Strigolactone Biosynthesis by Gibberellin Signaling
Ito, S., Yamagami, D., Umehara, M., Hanada, A., Yoshida, S., Sasaki, Y., Yajima, S., Kyozuka, J., Ueguchi‐Tanaka, M., Matsuoka, M., et al. (2017) · PLANT PHYSIOLOGY · doi:10.1104/pp.17.00301 · Cited by 188 · see citing works
Self-citationZhao, L., Zhou, X. E., Yi, W., Wu, Z., Liu, Y., Kang, Y., Hou, L., de Waal, P. W., Li, S., Jiang, Y., et al. (2015) · Cell Research · doi:10.1038/cr.2015.122 · Cited by 183 · see citing works
Gibberellin in plant height control: old player, new story
Wang, Y., Zhao, J., Lu, W., & Deng, D. (2017) · Plant Cell Reports · doi:10.1007/s00299-017-2104-5 · Cited by 181 · see citing works
Sang, D., Chen, D., Liu, G., Liang, Y. Q., Huang, L., Meng, X., Chu, J., Sun, X., Dong, G., Yuan, Y., et al. (2014) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1411859111 · Cited by 180 · see citing works
Unveiling the functional diversity of the alpha/beta hydrolase superfamily in the plant kingdom
Mindrebo, J. T., Nartey, C. M., Seto, Y., et al. (2016) · Current Opinion in Structural Biology · doi:10.1016/j.sbi.2016.08.005 · Cited by 180 · see citing works
Lanfranco, L., Fiorilli, V., Venice, F., & Bonfante, P. (2017) · Journal of Experimental Botany · doi:10.1093/jxb/erx432 · Cited by 180 · see citing works
Gibberellin Promotes Shoot Branching in the Perennial Woody PlantJatropha curcas
Ni, J., Gao, C., Chen, M.-S., Pan, B.-Z., Ye, K., & Xu, Z. (2015) · Plant and Cell Physiology · doi:10.1093/pcp/pcv089 · Cited by 179 · see citing works
Gibberellic Acid: A Versatile Regulator of Plant Growth, Development and Stress Responses
Shah, S. H., Islam, S., Mohammad, F., & Siddiqui, M. H. (2023) · Journal of Plant Growth Regulation · doi:10.1007/s00344-023-11035-7 · Cited by 191 · see citing works
Apocarotenoids Involved in Plant Development and Stress Response
Felemban, A., Braguy, J., Zurbriggen, M. D., & Al‐Babili, S. (2019) · Frontiers in Plant Science · doi:10.3389/fpls.2019.01168 · Cited by 173 · see citing works
Lv, S., Zhang, Y., Li, C., Liu, Z., Yang, N., Pan, L., Wu, J., Wang, J., Yang, J., Lv, Y., et al. (2017) · New Phytologist · doi:10.1111/nph.14813 · Cited by 173 · see citing works
Chemical regulators of plant hormones and their applications in basic research and agriculture*
Jiang, K., & Asami, T. (2018) · Bioscience Biotechnology and Biochemistry · doi:10.1080/09168451.2018.1462693 · Cited by 170 · see citing works
Self-citationConn, C. E., & Nelson, D. C. (2016) · Frontiers in Plant Science · doi:10.3389/fpls.2015.01219 · Cited by 166 · see citing works
Exploiting DELLA Signaling in Cereals
Velde, K. V. D., Ruelens, P., Geuten, K. P., et al. (2017) · Trends in Plant Science · doi:10.1016/j.tplants.2017.07.010 · Cited by 156 · see citing works
Strigolactone regulates shoot development through a core signalling pathway
Bennett, T., Liang, Y., Seale, M., Ward, S. P., Müller, D., & Leyser, O. (2016) · Biology Open · doi:10.1242/bio.021402 · Cited by 155 · see citing works
The interaction of strigolactones with abscisic acid during the drought response in rice
Haider, I., Andreo‐Jiménez, B., Bruno, M., Bimbó, A., Floková, K., Abuauf, H. W., Ntui, V. O., Guo, X., Charnikhova, T. V., Al‐Babili, S., et al. (2018) · Journal of Experimental Botany · doi:10.1093/jxb/ery089 · Cited by 147 · see citing works
Genetics of Tillering in Rice and Barley
Hussien, A., Tavakol, E., Horner, D. S., Muñoz‐Amatriaín, M., Muehlbauer, G. J., & Rossini, L. (2014) · The Plant Genome · doi:10.3835/plantgenome2013.10.0032 · Cited by 148 · see citing works
What is going on with the hormonal control of flowering in plants?
Izawa, T. (2020) · The Plant Journal · doi:10.1111/tpj.15036 · Cited by 147 · see citing works
Takeda, N., Handa, Y., Tsuzuki, S., et al. (2014) · PLANT PHYSIOLOGY · doi:10.1104/pp.114.247700 · Cited by 144 · see citing works
Strigolactones Biosynthesis and Their Role in Abiotic Stress Resilience in Plants: A Critical Review
Saeed, W., Naseem, S., & Ali, Z. (2017) · Frontiers in Plant Science · doi:10.3389/fpls.2017.01487 · Cited by 145 · see citing works
Structural diversity in the strigolactones
Wang, Y., & Bouwmeester, H. J. (2018) · Journal of Experimental Botany · doi:10.1093/jxb/ery091 · Cited by 138 · see citing works
Waters, M. T., Scaffidi, A., Moulin, S., et al. (2015) · The Plant Cell · doi:10.1105/tpc.15.00146 · Cited by 140 · see citing works
Kapulnik, Y., & Koltai, H. (2014) · PLANT PHYSIOLOGY · doi:10.1104/pp.114.244939 · Cited by 140 · see citing works
Pearce, S. P., Huttly, A. K., Prosser, I. M., Li, Y., Vaughan, S. P., Gallova, B., Patil, A., Coghill, J. A., Dubcovsky, J., Hedden, P., et al. (2015) · BMC Plant Biology · doi:10.1186/s12870-015-0520-7 · Cited by 138 · see citing works
Functional redundancy in the control of seedling growth by the karrikin signaling pathway
Stanga, J. P., Morffy, N., & Nelson, D. C. (2016) · Planta · doi:10.1007/s00425-015-2458-2 · Cited by 136 · see citing works
The Many Models of Strigolactone Signaling
Bürger, M., & Chory, J. (2020) · Trends in Plant Science · doi:10.1016/j.tplants.2019.12.009 · Cited by 136 · see citing works
Emerging Roles of Strigolactones in Plant Responses to Stress and Development
Pandey, A., Sharma, M., & Pandey, G. K. (2016) · Frontiers in Plant Science · doi:10.3389/fpls.2016.00434 · Cited by 135 · see citing works
E3 Ubiquitin Ligases: Key Regulators of Hormone Signaling in Plants
Kelley, D. R. (2018) · Molecular & Cellular Proteomics · doi:10.1074/mcp.mr117.000476 · Cited by 134 · see citing works
Evolution of strigolactone receptors by gradual neo-functionalization of KAI2 paralogues
Bythell‐Douglas, R., Rothfels, C. J., Stevenson, D. W., Graham, S. W., Wong, G. K., Nelson, D. C., & Bennett, T. (2017) · BMC Biology · doi:10.1186/s12915-017-0397-z · Cited by 132 · see citing works
Wu, J., Yan, G., Duan, Z., Wang, Z., Kang, C., Guo, L., Liu, K., Tu, J., Shen, J., Yi, B., et al. (2020) · Frontiers in Plant Science · doi:10.3389/fpls.2020.00577 · Cited by 133 · see citing works
Strigolactones: new plant hormones in action
Zwanenburg, B., Pospíšil, T., & Zeljkovıć, S. Ć. (2016) · Planta · doi:10.1007/s00425-015-2455-5 · Cited by 131 · see citing works
Signalling and responses to strigolactones and karrikins
Smith, S. M., & Li, J. (2014) · Current Opinion in Plant Biology · doi:10.1016/j.pbi.2014.06.003 · Cited by 130 · see citing works
Shedding light on integrative GA signaling
Xu, H., Liu, Q., Yao, T., et al. (2014) · Current Opinion in Plant Biology · doi:10.1016/j.pbi.2014.06.010 · Cited by 129 · see citing works
Regulation of axillary shoot development
Janssen, B. J., Drummond, R., & Snowden, K. C. (2013) · Current Opinion in Plant Biology · doi:10.1016/j.pbi.2013.11.004 · Cited by 126 · see citing works
Strigolactone biosynthesis and signaling in plant development
Lopez‐Obando, M., Ligerot, Y., Bonhomme, S., Boyer, F., & Rameau, C. (2015) · Development · doi:10.1242/dev.120006 · Cited by 124 · see citing works
Contribution of strigolactone in plant physiology, hormonal interaction and abiotic stresses
Bhoi, A., Yadu, B., Chandra, J., & Keshavkant, S. (2021) · Planta · doi:10.1007/s00425-021-03678-1 · Cited by 124 · see citing works
Strigolactone biosynthesis and perception
Seto, Y., & Yamaguchi, S. (2014) · Current Opinion in Plant Biology · doi:10.1016/j.pbi.2014.06.001 · Cited by 120 · see citing works
Smoke and Hormone Mirrors: Action and Evolution of Karrikin and Strigolactone Signaling
Morffy, N., Faure, L., & Nelson, D. C. (2016) · Trends in Genetics · doi:10.1016/j.tig.2016.01.002 · Cited by 118 · see citing works
Chesterfield, R. J., Vickers, C. E., & Beveridge, C. A. (2020) · Trends in Plant Science · doi:10.1016/j.tplants.2020.06.005 · Cited by 118 · see citing works
Highlights in gibberellin research: A tale of the dwarf and the slender
Shani, E., Hedden, P., & Sun, T. (2024) · PLANT PHYSIOLOGY · doi:10.1093/plphys/kiae044 · Cited by 120 · see citing works
The karrikin response system of A rabidopsis
Waters, M. T., Scaffidi, A., Sun, Y. K., Flematti, G. R., & Smith, S. M. (2014) · The Plant Journal · doi:10.1111/tpj.12430 · Cited by 117 · see citing works
Structural Requirements of Strigolactones for Shoot Branching Inhibition in Rice and Arabidopsis
Umehara, M., Cao, M., Akiyama, K., Akatsu, T., Seto, Y., Hanada, A., Li, W., Takeda‐Kamiya, N., Morimoto, Y., & Yamaguchi, S. (2015) · Plant and Cell Physiology · doi:10.1093/pcp/pcv028 · Cited by 115 · see citing works
DWARF3 Participates in an SCF Complex and Associates with DWARF14 to Suppress Rice Shoot Branching
Zhao, J., Wang, T., Wang, M., Liu, Y., Yuan, S., Gao, Y., Yin, L., Sun, W., Peng, L., Zhang, W., et al. (2014) · Plant and Cell Physiology · doi:10.1093/pcp/pcu045 · Cited by 113 · see citing works
Xu, L., Yuan, K., Yuan, M., et al. (2020) · Molecular Plant · doi:10.1016/j.molp.2020.02.009 · Cited by 114 · see citing works
Toh, S., Holbrook‐Smith, D., Stokes, M. E., Tsuchiya, Y., & McCourt, P. (2014) · Chemistry & Biology · doi:10.1016/j.chembiol.2014.07.005 · Cited by 111 · see citing works
Strigolactones and their crosstalk with other phytohormones
Omoarelojie, L. O., Kulkarni, M. G., Finnie, J. F., & Staden, J. V. (2019) · Annals of Botany · doi:10.1093/aob/mcz100 · Cited by 110 · see citing works
Stereospecificity in strigolactone biosynthesis and perception
Flematti, G. R., Scaffidi, A., Waters, M. T., et al. (2016) · Planta · doi:10.1007/s00425-016-2523-5 · Cited by 107 · see citing works
The molecular and genetic regulation of shoot branching
Luo, Z., Janssen, B. J., & Snowden, K. C. (2021) · PLANT PHYSIOLOGY · doi:10.1093/plphys/kiab071 · Cited by 104 · see citing works
Martínez-Bello, L., Möritz, T., & López‐Díaz, I. (2015) · Journal of Experimental Botany · doi:10.1093/jxb/erv300 · Cited by 103 · see citing works
Strigolactones positively regulate chilling tolerance in pea and in Arabidopsis
Cooper, J. W., Hu, Y., Beyyoudh, L., et al. (2018) · Plant Cell & Environment · doi:10.1111/pce.13147 · Cited by 102 · see citing works
Interactions of Gibberellins with Phytohormones and Their Role in Stress Responses
Castro-Camba, R., Sánchez, C., Vidal, N., et al. (2022) · Horticulturae · doi:10.3390/horticulturae8030241 · Cited by 100 · see citing works
Strigolactone signalling: standing on the shoulders of DWARFs
Bennett, T., & Leyser, O. (2014) · Current Opinion in Plant Biology · doi:10.1016/j.pbi.2014.08.001 · Cited by 95 · see citing works
Fellowship of the rings: a saga of strigolactones and other small signals
Machin, D. C., Hamon‐Josse, M., & Bennett, T. (2019) · New Phytologist · doi:10.1111/nph.16135 · Cited by 87 · see citing works
Strigolactones, karrikins and beyond
Cuyper, C. D., Struk, S., Braem, L., Gevaert, K., Jaeger, G. D., & Goormachtig, S. (2017) · Plant Cell & Environment · doi:10.1111/pce.12996 · Cited by 87 · see citing works
Possible Roles of Strigolactones during Leaf Senescence
Yamada, Y., & Umehara, M. (2015) · Plants · doi:10.3390/plants4030664 · Cited by 86 · see citing works
Apocarotenoids: A New Carotenoid-Derived Pathway
Moreno, J. C., & Stange, C. (2016) · Sub-cellular biochemistry/Subcellular biochemistry · doi:10.1007/978-3-319-39126-7_9 · Cited by 84 · see citing works
Biological Functions of Strigolactones and Their Crosstalk With Other Phytohormones
Wu, F., Gao, Y., Yang, W., Sui, N., & Zhu, J. (2022) · Frontiers in Plant Science · doi:10.3389/fpls.2022.821563 · Cited by 86 · see citing works
Bouwmeester, H. J., Li, C., Thiombiano, B., Rahimi, M., & Dong, L. (2020) · PLANT PHYSIOLOGY · doi:10.1093/plphys/kiaa066 · Cited by 83 · see citing works
Strigolactone: An Emerging Growth Regulator for Developing Resilience in Plants
Alvi, A. F., Sehar, Z., Fatma, M., Masood, A., & Khan, N. A. (2022) · Plants · doi:10.3390/plants11192604 · Cited by 86 · see citing works
Structural analysis of HTL and D14 proteins reveals the basis for ligand selectivity in Striga
Xu, Y., Miyakawa, T., Nosaki, S., Nakamura, A., Lyu, Y., Nakamura, H., Ohto, U., Ishida, H., Shimizu, T., Asami, T., et al. (2018) · Nature Communications · doi:10.1038/s41467-018-06452-2 · Cited by 83 · see citing works
Self-citationHu, J., Ji, Y., Hu, X., Sun, S., & Wang, X. (2019) · Plant Communications · doi:10.1016/j.xplc.2019.100014 · Cited by 83 · see citing works
Sun, H., Guo, X., Zhu, X., et al. (2023) · Molecular Plant · doi:10.1016/j.molp.2023.01.009 · Cited by 82 · see citing works
Salicylic acid inhibits gibberellin signaling through receptor interactions
Xiao-dong, Y., Cui, X., Wu, C., Shi, S., & Yan, S. (2022) · Molecular Plant · doi:10.1016/j.molp.2022.10.001 · Cited by 82 · see citing works
Regulatory mechanisms of strigolactone perception in rice
Hu, Q., Liu, H., He, Y., Hao, Y., Yan, J., Liu, S., Huang, X., Yan, Z., Zhang, D., Ban, X., et al. (2024) · Cell · doi:10.1016/j.cell.2024.10.009 · Cited by 81 · see citing works
The importance of strigolactone transport regulation for symbiotic signaling and shoot branching
Borghi, L., Liu, G., Emonet, A., Kretzschmar, T., & Martinoia, E. (2016) · Planta · doi:10.1007/s00425-016-2503-9 · Cited by 76 · see citing works
Lessons from a century of apical dominance research
Beveridge, C. A., Rameau, C., & Yapa, A. W. (2023) · Journal of Experimental Botany · doi:10.1093/jxb/erad137 · Cited by 80 · see citing works
The Role of Dwarfing Traits in Historical and Modern Agriculture with a Focus on RicePreprint
Ferrero‐Serrano, Á., Cantos, C. F., & Assmann, S. M. (2019) · Cold Spring Harbor Perspectives in Biology · doi:10.1101/cshperspect.a034645 · Cited by 77 · see citing works
Zhuang, L., Ge, Y., Wang, J., Yu, J., Yang, Z., & Huang, B. (2019) · Plant Science · doi:10.1016/j.plantsci.2019.110168 · Cited by 70 · see citing works
Ito, S., Nozoye, T., Sasaki, E., Imai, M., Shiwa, Y., Shibata-Hatta, M., Ishige, T., Fukui, K., Ito, K., Nakanishi, H., et al. (2015) · PLoS ONE · doi:10.1371/journal.pone.0119724 · Cited by 70 · see citing works
Self-citationTian, Z., Zhang, Y., Zhu, L., Jiang, B., Wang, H., Gao, R., Friml, J., & Xiao, G. (2022) · The Plant Cell · doi:10.1093/plcell/koac270 · Cited by 67 · see citing works
Signaling network regulating plant branching: Recent advances and new challenges
Kotov, A. A., Kotova, L. M., & Romanov, G. A. (2021) · Plant Science · doi:10.1016/j.plantsci.2021.110880 · Cited by 66 · see citing works
Ligand–receptor interactions in plant hormone signaling
Takeuchi, J., Fukui, K., Seto, Y., Takaoka, Y., & Okamoto, M. (2020) · The Plant Journal · doi:10.1111/tpj.15115 · Cited by 65 · see citing works
Self-citationOrigins of strigolactone and karrikin signaling in plants
Qia, W., Smith, S. M., & Huang, J. (2021) · Trends in Plant Science · doi:10.1016/j.tplants.2021.11.009 · Cited by 66 · see citing works
Potential of rice tillering for sustainable food production
Takai, T. (2023) · Journal of Experimental Botany · doi:10.1093/jxb/erad422 · Cited by 68 · see citing works
Cellular events of strigolactone signalling and their crosstalk with auxin in roots: Fig. 1.
Koltai, H. (2015) · Journal of Experimental Botany · doi:10.1093/jxb/erv178 · Cited by 65 · see citing works
Stes, E., Depuydt, S., Keyser, A. D., Matthys, C., Audenaert, K., Yoneyama, K., Werbrouck, S., Goormachtig, S., & Vereecke, D. (2015) · Journal of Experimental Botany · doi:10.1093/jxb/erv309 · Cited by 65 · see citing works
Strigolactone derivatives for potential crop enhancement applications
Screpanti, C., Fonné‐Pfister, R., Lumbroso, A., Rendine, S., Lachia, M., & Mesmaeker, A. D. (2016) · Bioorganic & Medicinal Chemistry Letters · doi:10.1016/j.bmcl.2016.03.072 · Cited by 64 · see citing works
- Authors
- Nakamura, H., Xue, Y.-L., Miyakawa, T., Hou, F., Qin, H.-M., Fukui, K., Shi, X., Ito, E., Ito, S., Park, S.-H., Miyauchi, Y., Asano, A., Totsuka, N., Ueda, T., Tanokura, M., & Asami, T.
- Affiliations
- The University of Tokyo (JP)
- Japan Science and Technology Agency (JP)
- Corresponding author
- Asami, Tadao
- ORCID
- Venue
- Nature Communications
- Published
- 2013-10-17
- Volume
- 4
- Issue
- 1
- Pages
- 2613-2613
- ISSN
- 2041-1723 (ISSN-L)
- OpenAlex
- W2013437585
- Semantic Scholar
- 517d693439f7c37658d8c5832dcb0dfd918e7ec5
- Cited by
- 378
- References
- 55
- Citations by year
- 2026: 18 · 2025: 15 · 2024: 23 · 2023: 31 · 2022: 29 · 2021: 28 · 2020: 31 · 2019: 32 · 2018: 32 · 2017: 39 · 2016: 39 · 2015: 22 · 2014: 35 · 2013: 4
- FWCI
- 40.18
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Licence
- Locations
- Nature Communications (publishedVersion)
- PubMed (publishedVersion)
- RePEc: Research Papers in Economics (submittedVersion)
- Funders
- Ministry of Education, Culture, Sports, Science and Technology (CREST)
- Shimane University
- University of Tokyo
- Japan Society for the Promotion of Science (23228003, 20001009, 23248018, CREST, 24370019, 24114003)
- Japan Science and Technology Agency (CREST)
- Core Research for Evolutional Science and Technology
- Topics
- Life Sciences › Agricultural and Biological Sciences › Plant Science › Plant Parasitism and Resistance
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Plant biochemistry and biosynthesis
- Life Sciences › Agricultural and Biological Sciences › Plant Science › Plant Molecular Biology Research
- Keywords
- strigolactone perception, DWARF14, SLR1, DELLA proteins, shoot branching, plant hormone signaling, protein crystal structure, alpha/beta hydrolase, plant-fungal symbiosis, parasitic weeds
- MeSH terms
- Escherichia coli, Gibberellins, Hydrolases, Plant Growth Regulators, Plant Proteins, Recombinant Proteins, Oryza, 4-Butyrolactone, Signal Transduction, Crystallography, X-Ray, Gene Expression Regulation, Plant, Two-Hybrid System Techniques, Plants, Genetically Modified, Rhizosphere
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review