The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
How allosteric control of Staphylococcus aureus penicillin binding protein 2a enables methicillin resistance and physiological function
Open accessAbstract
Significance: Penicillin binding protein 2a imparts to the human pathogen Staphylococcus aureus resistance to β-lactam antibiotics. Our structural characterization of the allosteric basis governing its resistance mechanism identifies a basis for the design of new antibacterials that can both activate and inhibit this key resistance enzyme.
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Citations
Cites
Tipper, D. J., & Strominger, J. L. (1965) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.54.4.1133 · Cited by 1,008 · cited 3×
“Tipper DJ, Strominger JL (1965) Mechanism of action of penicillins: A proposal based on their structural similarity to acyl-D-alanyl-D-alanine.”
Background
Cited by
Methicillin-Resistant Staphylococcus aureus: Molecular Characterization, Evolution, and Epidemiology
Lakhundi, S., & Zhang, K. (2018) · Clinical Microbiology Reviews · doi:10.1128/cmr.00020-18 · Cited by 1,637
β-Lactams and β-Lactamase Inhibitors: An Overview
Bush, K., & Bradford, P. A. (2016) · Cold Spring Harbor Perspectives in Medicine · doi:10.1101/cshperspect.a025247 · Cited by 1,412
Mechanisms of Methicillin Resistance in Staphylococcus aureus
Peacock, S. J., & Paterson, G. K. (2015) · Annual Review of Biochemistry · doi:10.1146/annurev-biochem-060614-034516 · Cited by 656
Antibiotic Resistance and the MRSA Problem
Vestergaard, M., Frees, D., & Ingmer, H. (2019) · Microbiology Spectrum · doi:10.1128/microbiolspec.gpp3-0057-2018 · Cited by 490
Penicillin‐binding protein 2a of methicillin‐resistant Staphylococcus aureus
Fishovitz, J., Hermoso, J. A., Chang, M., & Mobashery, S. (2014) · IUBMB Life · doi:10.1002/iub.1289 · Cited by 279
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Metadata
- Authors
- Otero, L. H., Rojas-Altuve, A., Llarrull, L. I., Carrasco-López, C., Kumarasiri, M., Lastochkin, E., Fishovitz, J., Dawley, M., Hesek, D., Lee, M., Johnson, J. W., Fisher, J. F., Chang, M., Mobashery, S., & Hermoso, J. A.
- Venue
- Proceedings of the National Academy of Sciences
- Published
- 2013-10
- Volume
- 110
- Issue
- 42
- Pages
- 16808-16813
- ISSN
- 0027-8424 (ISSN-L)
- 1091-6490
- OpenAlex
- W2119877522
- Cited by
- 281
- References
- 1
- FWCI
- 15.93
- Type
- journal article
- Language
- en
- Open access
- bronze
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- The paper
- Otero, L. H., Rojas-Altuve, A., Llarrull, L. I., Carrasco-López, C., Kumarasiri, M., Lastochkin, E., Fishovitz, J., Dawley, M., Hesek, D., Lee, M., Johnson, J. W., Fisher, J. F., Chang, M., Mobashery, S., & Hermoso, J. A. (2013). How allosteric control of Staphylococcus aureus penicillin binding protein 2a enables methicillin resistance and physiological function. Proceedings of the National Academy of Sciences. https://doi.org/10.1073/pnas.1300118110
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
