The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.
Human NAIP and mouse NAIP1 recognize bacterial type III secretion needle protein for inflammasome activation
Open accessAbstract
Significance: Our analyses uncover general immunogenic activity of bacterial T3SS needle protein and identify human NAIP and mouse NAIP1 as cytosolic innate immune sensors of bacterial T3SS needle protein. These results, together with our previous studies, establish a complete framework for understanding NLRC4-mediated detection of bacterial virulence products by the NAIP family inflammasome receptors. The inflammasome-stimulating activity of bacterial T3SS needle proteins and the difference between mouse and human NAIP inflammasome also may provide guidance in vaccine development.
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Franchi, L., Amer, A., Body-Malapel, M., Kanneganti, T.-D., Özören, N., Jagirdar, R., Inohara, N., Vandenabeele, P., Bertin, J., Coyle, A., et al. (2006) · Nature Immunology · doi:10.1038/ni1346 · Cited by 1,131
Cytoplasmic flagellin activates caspase-1 and secretion of interleukin 1β via Ipaf
Miao, E. A., Alpuche-Aranda, C. M., Dors, M., Clark, A. E., Bader, M. W., Miller, S. I., & Aderem, A. (2006) · Nature Immunology · doi:10.1038/ni1344 · Cited by 1,127
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Self-citationInflammasomes: mechanism of action, role in disease, and therapeutics
Guo, H., Callaway, J. B., & Ting, J. P.-Y. (2015) · Nature Medicine · doi:10.1038/nm.3893 · Cited by 3,340
Inflammatory caspases are innate immune receptors for intracellular LPS
Shi, J., Zhao, Y., Wang, Y., Gao, W., Ding, J., Li, P., Hu, L., & Shao, F. (2014) · Nature · doi:10.1038/nature13683 · Cited by 2,285
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Salmonellae interactions with host processes
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Metadata
- Authors
- Yang, J., Zhao, Y., Shi, J., & Shao, F.
- Venue
- Proceedings of the National Academy of Sciences
- Published
- 2013-08-12
- Volume
- 110
- Issue
- 35
- Pages
- 14408-14413
- ISSN
- 0027-8424 (ISSN-L)
- 1091-6490
- OpenAlex
- W1975145629
- Cited by
- 414
- References
- 2
- FWCI
- 15.06
- Type
- journal article
- Language
- en
- Open access
- green
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