The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
An alternative polyadenylation mechanism coopted to the Arabidopsis RPP7 gene through intronic retrotransposon domestication
Open accessAbstract
Significance: We show the histone mark H3K9me2, which is known to mediate transposon silencing, to determine the choice between alternative polyadenylation sites within the Arabidopsis thaliana disease resistance gene RPP7 . High H3K9me2 levels recruited to the first RPP7 intron by the COPIA-R7 retrotransposon suppress use of a promoter-proximal polyadenylation site. Modulating H3K9me2 levels at this site shifts the balance between full-length and incomplete RPP7 transcripts. By recruiting H3K9me2-dependent polyadenylation control to RPP7 , the COPIA-R7 insertion provided a new switch to fine-tune RPP7 expression. Selective advantages resulting from this mechanism likely contributed to the domestication of COPIA-R7 at RPP7 .
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Cites
Mechanisms and Consequences of Alternative Polyadenylation
Di Giammartino, D. C., Nishida, K., & Manley, J. L. (2011) · Molecular Cell · doi:10.1016/j.molcel.2011.08.017 · Cited by 737
Cited by
Transcriptional networks in plant immunity
Tsuda, K., & Somssich, I. E. (2015) · New Phytologist · doi:10.1111/nph.13286 · Cited by 552
Disease Resistance Mechanisms in Plants
Andersen, E. J., Ali, S., Byamukama, E., Yen, Y., & Nepal, M. P. (2018) · Genes · doi:10.3390/genes9070339 · Cited by 434
A Truncated Singleton NLR Causes Hybrid Necrosis in Arabidopsis thaliana
Barragan, A. C., Collenberg, M., Wang, J., Lee, R. R. Q., Cher, W. Y., Rabanal, F. A., Ashkenazy, H., Weigel, D., & Chae, E. (2021) · Molecular Biology and Evolution · doi:10.1093/molbev/msaa245 · Cited by 46
Metadata
- Authors
- Tsuchiya, T., & Eulgem, T.
- Venue
- Proceedings of the National Academy of Sciences
- Published
- 2013-08-12
- Volume
- 110
- Issue
- 37
- Pages
- E3535-43
- ISSN
- 0027-8424 (ISSN-L)
- 1091-6490
- OpenAlex
- W2000365513
- Cited by
- 167
- References
- 1
- FWCI
- 17.20
- Type
- journal article
- Language
- en
- Open access
- green
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- Tsuchiya, T., & Eulgem, T. (2013). An alternative polyadenylation mechanism coopted to the Arabidopsis RPP7 gene through intronic retrotransposon domestication. Proceedings of the National Academy of Sciences. https://doi.org/10.1073/pnas.1312545110
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